GB1058258A - Alkyl derivatives of imidazo[1,2-a]pyridines - Google Patents
Alkyl derivatives of imidazo[1,2-a]pyridinesInfo
- Publication number
- GB1058258A GB1058258A GB4822465A GB4822465A GB1058258A GB 1058258 A GB1058258 A GB 1058258A GB 4822465 A GB4822465 A GB 4822465A GB 4822465 A GB4822465 A GB 4822465A GB 1058258 A GB1058258 A GB 1058258A
- Authority
- GB
- United Kingdom
- Prior art keywords
- pyridines
- imidazo
- alkyl derivatives
- alkyl
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 125000000217 alkyl group Chemical group 0.000 title abstract 3
- ICSNLGPSRYBMBD-UHFFFAOYSA-N 2-aminopyridine Chemical compound NC1=CC=CC=N1 ICSNLGPSRYBMBD-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000005283 haloketone group Chemical group 0.000 abstract 1
- 230000001631 hypertensive effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- -1 where R is H Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Compounds of the formula <FORM:1058258/C2/1> and their acid addition salts, where R is H, halogen or C1- 5 alkyl and R1 and R11 represent H or C1- 5 alkyl, are prepared by reacting an appropriate 2-aminopyridine with a haloaldehyde or haloketone. 1 - (21,21 - Dimethoxyethyl) - 2 - imino - 4 - methyl-pyridine is prepared as an intermediate. Pharmaceutical compositions comprise the compounds of the invention and a carrier. The compositions show hypertensive activity and may be administered either orally or parenterally.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT2014865 | 1965-09-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB1058258A true GB1058258A (en) | 1967-02-08 |
Family
ID=11164189
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB4822465A Expired GB1058258A (en) | 1965-09-10 | 1965-11-12 | Alkyl derivatives of imidazo[1,2-a]pyridines |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB1058258A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4727145A (en) * | 1986-09-22 | 1988-02-23 | Ortho Pharmaceutical Corporation | 2- Or 3- aryl substituted imidazo [1,2-a]pyridines |
-
1965
- 1965-11-12 GB GB4822465A patent/GB1058258A/en not_active Expired
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4727145A (en) * | 1986-09-22 | 1988-02-23 | Ortho Pharmaceutical Corporation | 2- Or 3- aryl substituted imidazo [1,2-a]pyridines |
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