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FR2666741B1 - Composition therapeutique pour inhiber l'agregation plaquettaire. - Google Patents

Composition therapeutique pour inhiber l'agregation plaquettaire.

Info

Publication number
FR2666741B1
FR2666741B1 FR9111435A FR9111435A FR2666741B1 FR 2666741 B1 FR2666741 B1 FR 2666741B1 FR 9111435 A FR9111435 A FR 9111435A FR 9111435 A FR9111435 A FR 9111435A FR 2666741 B1 FR2666741 B1 FR 2666741B1
Authority
FR
France
Prior art keywords
alkyl group
lower alkyl
platelet aggregation
therapeutic composition
inhibiting platelet
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9111435A
Other languages
English (en)
Other versions
FR2666741A1 (fr
Inventor
Akio Odawara
Odawara Akio
Yasuhiko Sasaki
Sasaki Yasuhiko
Sakae Murata
Murata Sakae
Hiroshi Narita
Narita Hiroshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2243728A external-priority patent/JPH078798B2/ja
Priority claimed from JP2243729A external-priority patent/JPH078799B2/ja
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Publication of FR2666741A1 publication Critical patent/FR2666741A1/fr
Application granted granted Critical
Publication of FR2666741B1 publication Critical patent/FR2666741B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)

Abstract

L'invention concerne une composition thérapeutique pour inhiber l'agrégation plaquettaire, qui comprend de l'acide acétylsalicylique ou un de ses sels pharmaceutiquement acceptables et un dérivé de 1,5-benzothiazépine de formule: (CF DESSIN DANS BOPI) dans laquelle R1 est un groupe alcoyle inférieur ou un groupe alcoxy inférieur, R2 est un atome d'hydrogène ou un groupe alcanoyle inférieur, R3 est un groupe alcoyle inférieur, R4 est un atome d'hydrogène ou un groupe alcoyle inférieur et R5 est un groupe alcoyle inférieur ou un atome d'halogène, ou un de ses sels pharmaceutiquement acceptables.
FR9111435A 1990-09-17 1991-09-17 Composition therapeutique pour inhiber l'agregation plaquettaire. Expired - Fee Related FR2666741B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2243728A JPH078798B2 (ja) 1990-09-17 1990-09-17 血小板凝集抑制組成物
JP2243729A JPH078799B2 (ja) 1990-09-17 1990-09-17 血小板凝集抑制組成物

Publications (2)

Publication Number Publication Date
FR2666741A1 FR2666741A1 (fr) 1992-03-20
FR2666741B1 true FR2666741B1 (fr) 1993-01-08

Family

ID=26536403

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9111435A Expired - Fee Related FR2666741B1 (fr) 1990-09-17 1991-09-17 Composition therapeutique pour inhiber l'agregation plaquettaire.

Country Status (9)

Country Link
US (1) US5387581A (fr)
EP (1) EP0476854B1 (fr)
KR (1) KR0145689B1 (fr)
AT (1) ATE106734T1 (fr)
CA (1) CA2049655C (fr)
DE (1) DE69102379T2 (fr)
DK (1) DK0476854T3 (fr)
ES (1) ES2057777T3 (fr)
FR (1) FR2666741B1 (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5637582A (en) * 1992-10-23 1997-06-10 Tanabe Seiyaku Co., Ltd. Peripheral circulation improving agent
DK0595526T3 (da) * 1992-10-23 1997-10-13 Tanabe Seiyaku Co Middel til at forbedre perifær cirkulation
MA24512A1 (fr) 1996-01-17 1998-12-31 Univ Vermont And State Agrienl Procede pour la preparation d'agents anticoagulants utiles dans le traitement de la thrombose
US20070190059A1 (en) * 1996-01-17 2007-08-16 Smithkline Beecham Corporation Antithrombotic agents
US20030235587A1 (en) * 1998-08-07 2003-12-25 Feuerstein Giora Z. Anticoagulant agents useful in treatment of thrombosis
US6010911A (en) * 1997-04-30 2000-01-04 Medtronic, Inc. Apparatus for performing a heparin-independent high sensitivity platelet function evaluation technique
WO2001087339A1 (fr) * 2000-05-15 2001-11-22 Smithkline Beecham Corporation Agents antitrhombotiques
AU2005248772B2 (en) * 2004-05-17 2010-11-25 Medtronic, Inc. Point of care heparin determination system

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4567175A (en) * 1983-06-03 1986-01-28 Tanabe Seiyaku Co., Ltd. 8-Chloro-1,5-benzothiazepine derivatives
US4590188A (en) * 1984-02-18 1986-05-20 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivatives and their pharmaceutical use
US4594342A (en) * 1984-04-10 1986-06-10 Tanabe Seiyaku Co., Ltd. 1,5-benzothiazepine derivative
FR2589358B1 (fr) * 1985-07-30 1987-12-04 Synthelabo Compositions pharmaceutiques a base de diltiazem et d'aspirine
DE3626097A1 (de) * 1986-07-31 1988-02-11 Goedecke Ag Wirkstoffkombination enthaltend diltiazem und acetylsalicylsaeure

Also Published As

Publication number Publication date
DE69102379T2 (de) 1994-09-29
DK0476854T3 (da) 1994-07-11
ES2057777T3 (es) 1994-10-16
EP0476854B1 (fr) 1994-06-08
ATE106734T1 (de) 1994-06-15
DE69102379D1 (de) 1994-07-14
EP0476854A1 (fr) 1992-03-25
KR920005986A (ko) 1992-04-27
CA2049655C (fr) 1996-11-12
KR0145689B1 (ko) 1998-08-17
CA2049655A1 (fr) 1992-03-18
US5387581A (en) 1995-02-07
FR2666741A1 (fr) 1992-03-20

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Legal Events

Date Code Title Description
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