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FR2597865B1 - NOVEL DERIVATIVES OF A BENZYL ALKYL CARBOXYLIC ACID SUBSTITUTED BY A RADICAL 4-PYRIDINYL AMINOCARBONYL, THEIR PREPARATION PROCESS, THE NEW INTERMEDIATES OBTAINED, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS - Google Patents

NOVEL DERIVATIVES OF A BENZYL ALKYL CARBOXYLIC ACID SUBSTITUTED BY A RADICAL 4-PYRIDINYL AMINOCARBONYL, THEIR PREPARATION PROCESS, THE NEW INTERMEDIATES OBTAINED, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS

Info

Publication number
FR2597865B1
FR2597865B1 FR8606179A FR8606179A FR2597865B1 FR 2597865 B1 FR2597865 B1 FR 2597865B1 FR 8606179 A FR8606179 A FR 8606179A FR 8606179 A FR8606179 A FR 8606179A FR 2597865 B1 FR2597865 B1 FR 2597865B1
Authority
FR
France
Prior art keywords
aminocarbonyl
pyridinyl
medicaments
radical
carboxylic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR8606179A
Other languages
French (fr)
Other versions
FR2597865A1 (en
Inventor
Francoise Delevallee
Jean-Paul Vevert
Jean-Claude Gasc
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis France
Original Assignee
Roussel Uclaf SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf SA filed Critical Roussel Uclaf SA
Priority to FR8606179A priority Critical patent/FR2597865B1/en
Publication of FR2597865A1 publication Critical patent/FR2597865A1/en
Application granted granted Critical
Publication of FR2597865B1 publication Critical patent/FR2597865B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FR8606179A 1986-04-29 1986-04-29 NOVEL DERIVATIVES OF A BENZYL ALKYL CARBOXYLIC ACID SUBSTITUTED BY A RADICAL 4-PYRIDINYL AMINOCARBONYL, THEIR PREPARATION PROCESS, THE NEW INTERMEDIATES OBTAINED, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS Expired - Fee Related FR2597865B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR8606179A FR2597865B1 (en) 1986-04-29 1986-04-29 NOVEL DERIVATIVES OF A BENZYL ALKYL CARBOXYLIC ACID SUBSTITUTED BY A RADICAL 4-PYRIDINYL AMINOCARBONYL, THEIR PREPARATION PROCESS, THE NEW INTERMEDIATES OBTAINED, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8606179A FR2597865B1 (en) 1986-04-29 1986-04-29 NOVEL DERIVATIVES OF A BENZYL ALKYL CARBOXYLIC ACID SUBSTITUTED BY A RADICAL 4-PYRIDINYL AMINOCARBONYL, THEIR PREPARATION PROCESS, THE NEW INTERMEDIATES OBTAINED, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS

Publications (2)

Publication Number Publication Date
FR2597865A1 FR2597865A1 (en) 1987-10-30
FR2597865B1 true FR2597865B1 (en) 1990-11-09

Family

ID=9334724

Family Applications (1)

Application Number Title Priority Date Filing Date
FR8606179A Expired - Fee Related FR2597865B1 (en) 1986-04-29 1986-04-29 NOVEL DERIVATIVES OF A BENZYL ALKYL CARBOXYLIC ACID SUBSTITUTED BY A RADICAL 4-PYRIDINYL AMINOCARBONYL, THEIR PREPARATION PROCESS, THE NEW INTERMEDIATES OBTAINED, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS

Country Status (1)

Country Link
FR (1) FR2597865B1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2683817B1 (en) * 1991-11-18 1994-02-25 Upsa Laboratoires NOVEL ALPHA-AMINO N-PYRIDYL BENZENE PROPANAMIDE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
US6350763B1 (en) * 1999-07-21 2002-02-26 Boehringer Ingelheim Pharmaceuticals, Inc. Small molecules useful in the treatment of inflammation disease
GB9929979D0 (en) 1999-12-17 2000-02-09 Darwin Discovery Ltd Hydroxamic acid derivatives
SI2435409T1 (en) 2009-05-28 2014-12-31 Novartis Ag Substituted aminopropionic derivatives as neprilysin inhibitors
EA201101672A1 (en) 2009-05-28 2012-06-29 Новартис Аг SUBSTITUTED DERIVATIVES OF AMINOISAL ACID AS NEPRILISIN INHIBITORS
JO2967B1 (en) 2009-11-20 2016-03-15 نوفارتس ايه جي Substituted carbamoylmethylamino acetic acid derivatives as novel NEP inhibitors
AU2014216417B2 (en) 2013-02-14 2016-05-12 Novartis Ag Substituted bisphenyl butanoic acid derivatives as NEP inhibitors with improved in vivo efficacy
JP6295277B2 (en) 2013-02-14 2018-03-14 ノバルティス アーゲー Substituted bisphenylbutanoic acid phosphonic acid derivatives as NEP (neutral endopeptidase) inhibitors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB901312A (en) * 1958-11-04 1962-07-18 Irwin Neisler & Co Pyridylcarbamyl lower alkane derivatives and processes for preparing them

Also Published As

Publication number Publication date
FR2597865A1 (en) 1987-10-30

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Legal Events

Date Code Title Description
CA Change of address
CD Change of name or company name
TP Transmission of property
ST Notification of lapse