FR2358156A1 - Nouvel analogue de la desoxystreptamine et ses sels, leur procede de preparation et leur application comme medicaments - Google Patents
Nouvel analogue de la desoxystreptamine et ses sels, leur procede de preparation et leur application comme medicamentsInfo
- Publication number
- FR2358156A1 FR2358156A1 FR7609334A FR7609334A FR2358156A1 FR 2358156 A1 FR2358156 A1 FR 2358156A1 FR 7609334 A FR7609334 A FR 7609334A FR 7609334 A FR7609334 A FR 7609334A FR 2358156 A1 FR2358156 A1 FR 2358156A1
- Authority
- FR
- France
- Prior art keywords
- desoxy
- prepd
- benzylidene
- methyl
- streptamine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- DTFAJAKTSMLKAT-JDCCYXBGSA-N 2-deoxystreptamine Chemical compound N[C@H]1C[C@@H](N)[C@H](O)[C@@H](O)[C@@H]1O DTFAJAKTSMLKAT-JDCCYXBGSA-N 0.000 title 1
- 230000000844 anti-bacterial effect Effects 0.000 title 1
- 125000006297 carbonyl amino group Chemical group [H]N([*:2])C([*:1])=O 0.000 title 1
- RYVMUASDIZQXAA-UHFFFAOYSA-N pyranoside Natural products O1C2(OCC(C)C(OC3C(C(O)C(O)C(CO)O3)O)C2)C(C)C(C2(CCC3C4(C)CC5O)C)C1CC2C3CC=C4CC5OC(C(C1O)O)OC(CO)C1OC(C1OC2C(C(OC3C(C(O)C(O)C(CO)O3)O)C(O)C(CO)O2)O)OC(CO)C(O)C1OC1OCC(O)C(O)C1O RYVMUASDIZQXAA-UHFFFAOYSA-N 0.000 title 1
- 241000588724 Escherichia coli Species 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
- C07H15/10—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical containing unsaturated carbon-to-carbon bonds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/02—Acyclic radicals, not substituted by cyclic structures
- C07H15/12—Acyclic radicals, not substituted by cyclic structures attached to a nitrogen atom of the saccharide radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/224—Cyclohexane rings substituted by at least two nitrogen atoms with only one saccharide radical directly attached to the cyclohexyl radical, e.g. destomycin, fortimicin, neamine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/22—Cyclohexane rings, substituted by nitrogen atoms
- C07H15/222—Cyclohexane rings substituted by at least two nitrogen atoms
- C07H15/226—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings
- C07H15/234—Cyclohexane rings substituted by at least two nitrogen atoms with at least two saccharide radicals directly attached to the cyclohexane rings attached to non-adjacent ring carbon atoms of the cyclohexane rings, e.g. kanamycins, tobramycin, nebramycin, gentamicin A2
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
L'invention a pour objet la 4-0/2',6'-diamino 2',3',6'- tridésoxy alpha ,D ribohexophyranostyl/6-0-/3''-N-méthylamino 3"-désoxy alpha ,D glucopyranosyl/2-désoxy streptamine, de formule :
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7609334A FR2358156A1 (fr) | 1976-03-31 | 1976-03-31 | Nouvel analogue de la desoxystreptamine et ses sels, leur procede de preparation et leur application comme medicaments |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7609334A FR2358156A1 (fr) | 1976-03-31 | 1976-03-31 | Nouvel analogue de la desoxystreptamine et ses sels, leur procede de preparation et leur application comme medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FR2358156A1 true FR2358156A1 (fr) | 1978-02-10 |
| FR2358156B1 FR2358156B1 (fr) | 1978-12-08 |
Family
ID=9171208
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FR7609334A Granted FR2358156A1 (fr) | 1976-03-31 | 1976-03-31 | Nouvel analogue de la desoxystreptamine et ses sels, leur procede de preparation et leur application comme medicaments |
Country Status (1)
| Country | Link |
|---|---|
| FR (1) | FR2358156A1 (fr) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0008965A3 (en) * | 1978-09-06 | 1980-04-02 | Roussel-Uclaf | Aminoglycosides derived from desoxystreptamin and their salts, their method of preparation and pharmaceutical compositions containing them |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2209745A1 (fr) * | 1972-12-08 | 1974-07-05 | Microbial Chem Res Found | |
| FR2263746A1 (en) * | 1974-03-12 | 1975-10-10 | Roussel Uclaf | N-methyl-kanamycin B - with broad-spectrum antibacterial activity, esp. against staphylococcal and coliform infections |
-
1976
- 1976-03-31 FR FR7609334A patent/FR2358156A1/fr active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2209745A1 (fr) * | 1972-12-08 | 1974-07-05 | Microbial Chem Res Found | |
| FR2263746A1 (en) * | 1974-03-12 | 1975-10-10 | Roussel Uclaf | N-methyl-kanamycin B - with broad-spectrum antibacterial activity, esp. against staphylococcal and coliform infections |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0008965A3 (en) * | 1978-09-06 | 1980-04-02 | Roussel-Uclaf | Aminoglycosides derived from desoxystreptamin and their salts, their method of preparation and pharmaceutical compositions containing them |
| FR2435481A1 (fr) * | 1978-09-06 | 1980-04-04 | Roussel Uclaf | Nouveaux aminoglycosides derives de la desoxystreptamine et leurs sels, procede de preparation et application a titre de medicaments |
Also Published As
| Publication number | Publication date |
|---|---|
| FR2358156B1 (fr) | 1978-12-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| ST | Notification of lapse |