FI98814B - Menetelmä puhtaan kaptopriilin valmistamiseksi - Google Patents

Menetelmä puhtaan kaptopriilin valmistamiseksi

Info

Publication number: FI98814B
Authority: FI; Finland
Prior art keywords: substrate; captopril; alkali metal; metal hydroxide; pure
Prior art date: 1989-11-06

Application number

FI905467A

Other languages

English (en)

Swedish (sv)

Other versions

FI98814C (fi

FI905467A0 (fi

Inventor

Neal G Anderson

David A Lust

Barbara J Bennett

Alan F Feldman

Robert E Polomski

Original Assignee

Squibb & Sons Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-11-06

Filing date

1990-11-05

Publication date

1997-05-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23714462&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI98814(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1990-11-05 Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc

1990-11-05 Publication of FI905467A0 publication Critical patent/FI905467A0/fi

1997-05-15 Application granted granted Critical

1997-05-15 Publication of FI98814B publication Critical patent/FI98814B/fi

1997-08-25 Publication of FI98814C publication Critical patent/FI98814C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Cardiology (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Heart & Thoracic Surgery (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Compounds Of Unknown Constitution (AREA)
Pyrrole Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Semiconductor Lasers (AREA)

FI905467A 1989-11-06 1990-11-05 Menetelmä puhtaan kaptopriilin valmistamiseksi FI98814C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US07/432,028 US5026873A (en)	1989-11-06	1989-11-06	Process for direct isolation of captopril
US43202889		1989-11-06

Publications (3)

Publication Number	Publication Date
FI905467A0 FI905467A0 (fi)	1990-11-05
FI98814B true FI98814B (fi)	1997-05-15
FI98814C FI98814C (fi)	1997-08-25

Family

ID=23714462

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI905467A FI98814C (fi)	1989-11-06	1990-11-05	Menetelmä puhtaan kaptopriilin valmistamiseksi

Country Status (29)

Country	Link
US (1)	US5026873A (fi)
EP (1)	EP0427435B1 (fi)
JP (1)	JPH03169856A (fi)
KR (1)	KR0163956B1 (fi)
CN (1)	CN1028169C (fi)
AT (1)	ATE119148T1 (fi)
AU (1)	AU635341B2 (fi)
CA (1)	CA2027377A1 (fi)
CY (1)	CY1852A (fi)
CZ (1)	CZ277714B6 (fi)
DE (1)	DE69017355T2 (fi)
DK (1)	DK0427435T3 (fi)
EG (1)	EG18964A (fi)
ES (1)	ES2068349T3 (fi)
FI (1)	FI98814C (fi)
HK (1)	HK109895A (fi)
HU (1)	HU208525B (fi)
IE (1)	IE67284B1 (fi)
IL (1)	IL96018A (fi)
MX (1)	MX166721B (fi)
MY (1)	MY106445A (fi)
NO (1)	NO904796L (fi)
NZ (1)	NZ235958A (fi)
PH (1)	PH26962A (fi)
PL (1)	PL287642A1 (fi)
PT (1)	PT95781B (fi)
RU (1)	RU2001909C1 (fi)
SK (1)	SK278604B6 (fi)
ZA (1)	ZA908523B (fi)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU208954B (en) *	1990-09-21	1994-02-28	Egyt Gyogyszervegyeszeti Gyar	Process for producing 1-(3-mercapto-(2s)-methyl-1-oxo-propyl)-l-prolyn
US5387697A (en) *	1994-06-13	1995-02-07	Merck & Co., Inc.	Process for the preparation of 1-[3-acetylthio-2(s)-methylpropanoyl]-l-proline
JP3980684B2 (ja) *	1996-10-11	2007-09-26	株式会社カネカ	高品質カプトプリルの簡便な製造方法
CN107652215A (zh) *	2017-09-19	2018-02-02	重庆西南制药二厂有限责任公司	一种卡托普利的制备方法
CN110146624B (zh) *	2019-06-14	2022-02-22	湖南汉森制药股份有限公司	一种卡托普利有关物质的检测方法
CN110950792A (zh) *	2019-12-11	2020-04-03	华中药业股份有限公司	一种卡托普利的改进制备方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4105776A (en) *	1976-06-21	1978-08-08	E. R. Squibb & Sons, Inc.	Proline derivatives and related compounds
AU509899B2 (en) *	1976-02-13	1980-05-29	E.R. Squibb & Sons, Inc.	Proline derivatives and related compounds
US4241076A (en) *	1978-02-21	1980-12-23	E. R. Squibb & Sons, Inc.	Halogenated substituted mercaptoacylamino acids
NL7809120A (nl) *	1978-09-07	1980-03-11	Oce Andeno B V Grubbenvorsterw	Werkwijze voor de bereiding van proline-derivaten.
US4297282A (en) *	1979-03-02	1981-10-27	Sumitomo Chemical Company, Limited	Resolution of mercaptopropionic acids
HU184082B (en) *	1979-12-29	1984-06-28	Egyt Gyogyszervegyeszeti Gyar	Process for preparing 1-3-/3mercapto-/2s/-methyl-propinyl/-pyrrolidine-/2s/-carboxylic acid
US4332726A (en) *	1980-08-25	1982-06-01	E. R. Squibb & Sons, Inc.	Purification of mercaptoacyl amino acids
JPS58124764A (ja) *	1982-01-20	1983-07-25	Kanegafuchi Chem Ind Co Ltd	光学活性チオ−ル化合物の製造法
KR870001570B1 (ko) *	1984-12-19	1987-09-04	보령제약 주식회사	피롤리딘 유도체의 제조방법
IL91581A (en) *	1988-09-13	1993-07-08	Sepracor Inc	Methods for preparing optically active captopril and its analogues

1989
- 1989-11-06 US US07/432,028 patent/US5026873A/en not_active Expired - Lifetime
1990
- 1990-10-10 AU AU63977/90A patent/AU635341B2/en not_active Ceased
- 1990-10-11 CA CA002027377A patent/CA2027377A1/en not_active Abandoned
- 1990-10-11 MY MYPI90001775A patent/MY106445A/en unknown
- 1990-10-16 PH PH41385A patent/PH26962A/en unknown
- 1990-10-16 IL IL9601890A patent/IL96018A/en not_active IP Right Cessation
- 1990-10-19 IE IE375990A patent/IE67284B1/en not_active IP Right Cessation
- 1990-10-24 ZA ZA908523A patent/ZA908523B/xx unknown
- 1990-10-29 DK DK90311824.8T patent/DK0427435T3/da active
- 1990-10-29 ES ES90311824T patent/ES2068349T3/es not_active Expired - Lifetime
- 1990-10-29 AT AT90311824T patent/ATE119148T1/de not_active IP Right Cessation
- 1990-10-29 DE DE69017355T patent/DE69017355T2/de not_active Expired - Fee Related
- 1990-10-29 EP EP90311824A patent/EP0427435B1/en not_active Expired - Lifetime
- 1990-10-31 MX MX023131A patent/MX166721B/es unknown
- 1990-11-02 CZ CS905405A patent/CZ277714B6/cs not_active IP Right Cessation
- 1990-11-02 SK SK5405-90A patent/SK278604B6/sk not_active IP Right Cessation
- 1990-11-04 EG EG600690A patent/EG18964A/xx active
- 1990-11-05 NZ NZ235958A patent/NZ235958A/xx unknown
- 1990-11-05 RU SU904831477A patent/RU2001909C1/ru not_active IP Right Cessation
- 1990-11-05 NO NO90904796A patent/NO904796L/no unknown
- 1990-11-05 PT PT95781A patent/PT95781B/pt not_active IP Right Cessation
- 1990-11-05 HU HU907031A patent/HU208525B/hu not_active IP Right Cessation
- 1990-11-05 FI FI905467A patent/FI98814C/fi active IP Right Grant
- 1990-11-05 KR KR1019900017821A patent/KR0163956B1/ko not_active Expired - Fee Related
- 1990-11-06 PL PL28764290A patent/PL287642A1/xx unknown
- 1990-11-06 CN CN90108901A patent/CN1028169C/zh not_active Expired - Fee Related
- 1990-11-06 JP JP2302311A patent/JPH03169856A/ja active Pending
1995
- 1995-07-06 HK HK109895A patent/HK109895A/en not_active IP Right Cessation
1996
- 1996-03-08 CY CY185296A patent/CY1852A/xx unknown

Also Published As

Publication number	Publication date
ATE119148T1 (de)	1995-03-15
FI98814C (fi)	1997-08-25
DE69017355D1 (de)	1995-04-06
NO904796D0 (no)	1990-11-05
ES2068349T3 (es)	1995-04-16
IE67284B1 (en)	1996-03-20
HUT55754A (en)	1991-06-28
IL96018A (en)	1996-05-14
IL96018A0 (en)	1991-07-18
HK109895A (en)	1995-07-14
RU2001909C1 (ru)	1993-10-30
CA2027377A1 (en)	1991-05-07
IE903759A1 (en)	1991-05-08
CS540590A3 (en)	1992-11-18
EG18964A (en)	1994-09-29
CN1051908A (zh)	1991-06-05
CN1028169C (zh)	1995-04-12
AU6397790A (en)	1991-05-09
PL287642A1 (en)	1991-05-20
HU208525B (en)	1993-11-29
SK278604B6 (en)	1997-11-05
AU635341B2 (en)	1993-03-18
PH26962A (en)	1992-12-28
MX166721B (es)	1993-01-29
NZ235958A (en)	1993-01-27
PT95781A (pt)	1991-09-13
MY106445A (en)	1995-05-30
EP0427435A1 (en)	1991-05-15
ZA908523B (en)	1991-08-28
JPH03169856A (ja)	1991-07-23
EP0427435B1 (en)	1995-03-01
NO904796L (no)	1991-05-07
DK0427435T3 (da)	1995-03-27
HU907031D0 (en)	1991-05-28
CY1852A (en)	1996-03-08
FI905467A0 (fi)	1990-11-05
CZ277714B6 (en)	1993-03-17
KR910009657A (ko)	1991-06-28
KR0163956B1 (ko)	1998-12-01
US5026873A (en)	1991-06-25
DE69017355T2 (de)	1995-06-29
PT95781B (pt)	1997-11-28

Publication	Publication Date	Title
EP1477514A4 (en)	2006-05-24	ETHYLENE VINYL ALCOHOL COPOLYMER RESIN COMPOSITIONS AND PRODUCTION METHOD THEREFOR
FI98814B (fi)	1997-05-15	Menetelmä puhtaan kaptopriilin valmistamiseksi
BR8703985A (pt)	1988-04-05	Processo para a recuperacao de rodio de solucoes aquosas contendo compostos de complexos de rodio
JPS5773143A (en)	1982-05-07	Extraction of cobalt (ii) from aqueous solution
CA2022187A1 (en)	1991-06-16	N,n-bis-phosphonomethyl taurine n-oxide and water-soluble salts thereof
DE69005984D1 (de)	1994-02-24	2-Hydroxy-3-phenoxypropylaminoverbindungen.
HUT53528A (en)	1990-11-28	Process for production of having antiviral effectg, well suluable in water stabil cristallic salts of 2',3' dideozoxiinozin- monohidrat, 2',3'-didezoxi-2'3'-didohydrotimidin monohydrate and 2',3' didezoxi-2'-fluor-inosine-hemihydrate and medical compositions containing these salts
BG47945A3 (bg)	1990-10-15	Метод за получаване на органичен цинков комплекс
FI910059A0 (fi)	1991-01-04	Kemiska foereningar.
PT81908B (pt)	1988-02-17	Processo para a fabricacao de carbonato de sodio anidro denso
AU7719587A (en)	1988-03-24	Process for preparing 2,3,5,6,-tetrachloropyridine
EP1065199A3 (en)	2003-11-05	"Process for the recovery of strong acids from aqueous solution"
GB1518549A (en)	1978-07-19	Filtration of titanium dioxide hydrolyzate sludge
FR2352069A1 (fr)	1977-12-16	Procede de phosphatation de metaux
GB1048907A (en)	1966-11-23	Penicillins
TH18762A (th)	1996-05-29	กรรมวิธีสำหรับเตรียมเกลือไอเซไธโอเนทเอสเทอร์
GEP19971039B (en)	1997-11-26	Method for production of acrylic acid
ES8300106A1 (es)	1982-11-01	Procedimiento para preparar compuesto de 2-(2-imidazolin-2-il)-piridina y quinolina.

Legal Events

Date	Code	Title	Description
1990-11-05	FG	Patent granted	Owner name: E.R. SQUIBB & SONS, INC.
1997-04-16	BB	Publication of examined application
2004-08-31	FG	Patent granted	Owner name: E.R. SQUIBB & SONS, INC.