FI973040L - Rasemointimenetelmä käytettäväksi levobupivakaiinin ja siihen läheisesti liittyvien piperidiinikarboksanilidipuudutusaineiden valmistuksessa - Google Patents
Rasemointimenetelmä käytettäväksi levobupivakaiinin ja siihen läheisesti liittyvien piperidiinikarboksanilidipuudutusaineiden valmistuksessa Download PDFInfo
- Publication number
- FI973040L FI973040L FI973040A FI973040A FI973040L FI 973040 L FI973040 L FI 973040L FI 973040 A FI973040 A FI 973040A FI 973040 A FI973040 A FI 973040A FI 973040 L FI973040 L FI 973040L
- Authority
- FI
- Finland
- Prior art keywords
- piperidinecarboxanilide
- levobupivacaine
- anesthetics
- preparation
- closely related
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Rolling Contact Bearings (AREA)
- Optical Head (AREA)
- Beans For Foods Or Fodder (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9501071.6A GB9501071D0 (en) | 1995-01-18 | 1995-01-18 | Racemisation |
| GB9501071 | 1995-01-18 | ||
| GB9600067 | 1996-01-12 | ||
| PCT/GB1996/000067 WO1996022281A1 (en) | 1995-01-18 | 1996-01-12 | Racemisation process for use in the manufacture of levobupivacaine and related piperidinecarboxanilide anaesthetic agents |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI973040L true FI973040L (fi) | 1997-07-17 |
| FI973040A0 FI973040A0 (fi) | 1997-07-17 |
| FI117437B FI117437B (fi) | 2006-10-13 |
Family
ID=10768271
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI973040A FI117437B (fi) | 1995-01-18 | 1997-07-17 | Menetelmä optisesti rikastetun levobupivakaiinin ja siihen läheisesti liittyvien piperidiinikarboksanilidiyhdisteiden rasemisoimiseksi |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0804417B1 (fi) |
| JP (1) | JP4015696B2 (fi) |
| KR (1) | KR100404390B1 (fi) |
| CN (1) | CN1172912C (fi) |
| AT (1) | ATE242214T1 (fi) |
| AU (1) | AU701221B2 (fi) |
| BR (1) | BR9606821A (fi) |
| CA (1) | CA2208522C (fi) |
| DE (1) | DE69628540T2 (fi) |
| DK (1) | DK0804417T3 (fi) |
| ES (1) | ES2201166T3 (fi) |
| FI (1) | FI117437B (fi) |
| GB (1) | GB9501071D0 (fi) |
| HU (1) | HU227426B1 (fi) |
| MX (1) | MX9705428A (fi) |
| NO (1) | NO308843B1 (fi) |
| PL (1) | PL184091B1 (fi) |
| PT (1) | PT804417E (fi) |
| WO (1) | WO1996022281A1 (fi) |
| ZA (1) | ZA96403B (fi) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BR0002246A (pt) * | 2000-04-06 | 2003-04-15 | Cristalia Prod Quimicos Farm | Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis |
| US20040001889A1 (en) | 2002-06-25 | 2004-01-01 | Guohua Chen | Short duration depot formulations |
| CN101797221B (zh) | 2002-12-13 | 2013-06-12 | 杜雷科特公司 | 包含高粘度液体载体材料的口服递药系统 |
| HUE032040T2 (en) | 2004-09-17 | 2017-09-28 | Durect Corp | Saib-containing (sucrose acetate-isobutyrate) sustained-release local anesthetic composition |
| US20070027105A1 (en) | 2005-07-26 | 2007-02-01 | Alza Corporation | Peroxide removal from drug delivery vehicle |
| US8337883B2 (en) | 2006-11-03 | 2012-12-25 | Durect Corporation | Transdermal delivery systems |
| AU2008335809A1 (en) | 2007-12-06 | 2009-06-18 | Durect Corporation | Methods useful for the treatment of pain, arthritic conditions, or inflammation associated with a chronic condition |
| US20100260844A1 (en) | 2008-11-03 | 2010-10-14 | Scicinski Jan J | Oral pharmaceutical dosage forms |
| CN102093284B (zh) * | 2010-12-29 | 2013-05-08 | 宜昌人福药业有限责任公司 | 富集哌啶-2-甲酰苯胺类旋光化合物的方法 |
| WO2014144975A1 (en) | 2013-03-15 | 2014-09-18 | Durect Corporation | Compositions with a rheological modifier to reduce dissolution variability |
| CA3028450A1 (en) | 2016-07-06 | 2018-01-11 | Durect Corporation | Oral dosage form with drug composition, barrier layer and drug layer |
| CN106187864B (zh) * | 2016-07-11 | 2018-11-23 | 江苏天和制药有限公司 | 一种由盐酸布比卡因制备高纯度布比卡因碱的方法 |
| WO2021146215A1 (en) | 2020-01-13 | 2021-07-22 | Durect Corporation | Sustained release drug delivery systems with reduced impurities and related methods |
| JP2024503402A (ja) | 2021-01-12 | 2024-01-25 | デュレクト コーポレーション | 徐放性薬物送達システム及び関連の方法 |
| US20250236897A1 (en) * | 2022-02-16 | 2025-07-24 | Teva Pharmaceuticals International Gmbh | Processes for preparation of avacopan and intermediates thereof |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2301498A1 (fr) * | 1975-02-20 | 1976-09-17 | Maggioni & C Spa | Methode pour la racemisation d'une lysine optiquement active |
-
1995
- 1995-01-18 GB GBGB9501071.6A patent/GB9501071D0/en active Pending
-
1996
- 1996-01-12 CN CNB961915242A patent/CN1172912C/zh not_active Expired - Lifetime
- 1996-01-12 PL PL96321378A patent/PL184091B1/pl unknown
- 1996-01-12 AU AU43948/96A patent/AU701221B2/en not_active Expired
- 1996-01-12 DE DE69628540T patent/DE69628540T2/de not_active Expired - Lifetime
- 1996-01-12 AT AT96900349T patent/ATE242214T1/de active
- 1996-01-12 HU HU9901418A patent/HU227426B1/hu unknown
- 1996-01-12 CA CA002208522A patent/CA2208522C/en not_active Expired - Lifetime
- 1996-01-12 KR KR1019970704822A patent/KR100404390B1/ko not_active Expired - Lifetime
- 1996-01-12 DK DK96900349T patent/DK0804417T3/da active
- 1996-01-12 WO PCT/GB1996/000067 patent/WO1996022281A1/en not_active Ceased
- 1996-01-12 ES ES96900349T patent/ES2201166T3/es not_active Expired - Lifetime
- 1996-01-12 PT PT96900349T patent/PT804417E/pt unknown
- 1996-01-12 EP EP96900349A patent/EP0804417B1/en not_active Expired - Lifetime
- 1996-01-12 BR BR9606821A patent/BR9606821A/pt unknown
- 1996-01-12 MX MX9705428A patent/MX9705428A/es unknown
- 1996-01-12 JP JP52210296A patent/JP4015696B2/ja not_active Expired - Lifetime
- 1996-01-18 ZA ZA96403A patent/ZA96403B/xx unknown
-
1997
- 1997-07-17 FI FI973040A patent/FI117437B/fi not_active IP Right Cessation
- 1997-07-17 NO NO973312A patent/NO308843B1/no not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI117437B (fi) | 2006-10-13 |
| PL321378A1 (en) | 1997-12-08 |
| JPH11501905A (ja) | 1999-02-16 |
| HU227426B1 (en) | 2011-05-30 |
| CN1168134A (zh) | 1997-12-17 |
| PT804417E (pt) | 2003-09-30 |
| KR19980701432A (ko) | 1998-05-15 |
| KR100404390B1 (ko) | 2004-01-31 |
| EP0804417B1 (en) | 2003-06-04 |
| FI973040A0 (fi) | 1997-07-17 |
| JP4015696B2 (ja) | 2007-11-28 |
| CA2208522A1 (en) | 1996-07-25 |
| CN1172912C (zh) | 2004-10-27 |
| NO973312D0 (no) | 1997-07-17 |
| NO308843B1 (no) | 2000-11-06 |
| ES2201166T3 (es) | 2004-03-16 |
| DE69628540T2 (de) | 2004-01-08 |
| HUP9901418A2 (hu) | 1999-08-30 |
| NO973312L (no) | 1997-07-17 |
| EP0804417A1 (en) | 1997-11-05 |
| ZA96403B (en) | 1997-01-20 |
| DK0804417T3 (da) | 2003-10-06 |
| DE69628540D1 (de) | 2003-07-10 |
| CA2208522C (en) | 2007-03-13 |
| WO1996022281A1 (en) | 1996-07-25 |
| MX9705428A (es) | 1997-11-29 |
| GB9501071D0 (en) | 1995-03-08 |
| AU4394896A (en) | 1996-08-07 |
| ATE242214T1 (de) | 2003-06-15 |
| PL184091B1 (pl) | 2002-08-30 |
| BR9606821A (pt) | 1997-12-23 |
| HUP9901418A3 (en) | 2001-01-29 |
| AU701221B2 (en) | 1999-01-21 |
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