EE03878B1 - 5-O-desosaminüül-6-O-metüülerütronoliid A derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete ühendite valmistamiseks - Google Patents

5-O-desosaminüül-6-O-metüülerütronoliid A derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete ühendite valmistamiseks

Info

Publication number: EE03878B1
Authority: EE; Estonia
Prior art keywords: preparation; methylerythronolide; desosaminyl; derivatives; bioactive compounds
Prior art date: 1995-10-09

Application number

EE9800109A

Other languages

English (en)

Other versions

EE9800109A (et

Inventor

Bonnet Alain

Chappert Bernadette

Lagouardat Jacques

Original Assignee

Hoechst Marion Roussel

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-10-09

Filing date

1996-10-08

Publication date

2002-10-15

1996-10-08 Application filed by Hoechst Marion Roussel filed Critical Hoechst Marion Roussel

1998-10-15 Publication of EE9800109A publication Critical patent/EE9800109A/et

2002-10-15 Publication of EE03878B1 publication Critical patent/EE03878B1/et

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
- C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
- C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

EE9800109A 1995-10-09 1996-10-08 5-O-desosaminüül-6-O-metüülerütronoliid A derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete ühendite valmistamiseks EE03878B1 (et)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR9511861A FR2739620B1 (fr)	1995-10-09	1995-10-09	Nouveaux derives de la 5-0-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs
PCT/FR1996/001567 WO1997013774A2 (fr)	1995-10-09	1996-10-08	Nouveaux derives de la 5-o-desosaminyl 6-o-methyl erythronolide a, leur procede de preparation et leur application a la preparation de produits biologiquement actifs

Publications (2)

Publication Number	Publication Date
EE9800109A EE9800109A (et)	1998-10-15
EE03878B1 true EE03878B1 (et)	2002-10-15

Family

ID=9483377

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
EE9800109A EE03878B1 (et)	1995-10-09	1996-10-08	5-O-desosaminüül-6-O-metüülerütronoliid A derivaadid, nende valmistamismeetod ja kasutamine bioaktiivsete ühendite valmistamiseks

Country Status (33)

Country	Link
US (1)	US6011142A (et)
EP (1)	EP0854879B1 (et)
JP (1)	JP4327248B2 (et)
KR (1)	KR100451063B1 (et)
CN (1)	CN1067401C (et)
AP (1)	AP888A (et)
AR (1)	AR004688A1 (et)
AT (1)	ATE212034T1 (et)
AU (1)	AU708351B2 (et)
BG (1)	BG63752B1 (et)
BR (1)	BR9610959A (et)
CA (1)	CA2231562C (et)
CZ (1)	CZ293430B6 (et)
DE (1)	DE69618607T2 (et)
DK (1)	DK0854879T3 (et)
EA (1)	EA000765B1 (et)
EE (1)	EE03878B1 (et)
ES (1)	ES2171722T3 (et)
FR (1)	FR2739620B1 (et)
GE (1)	GEP20032899B (et)
HU (1)	HUP9900136A3 (et)
IL (1)	IL123613A0 (et)
MX (1)	MX9802655A (et)
NO (1)	NO312592B1 (et)
PL (1)	PL183645B1 (et)
PT (1)	PT854879E (et)
RO (1)	RO118874B1 (et)
SI (1)	SI0854879T1 (et)
SK (1)	SK283619B6 (et)
TR (1)	TR199800624T1 (et)
UA (1)	UA52621C2 (et)
WO (1)	WO1997013774A2 (et)
ZA (1)	ZA966666B (et)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2777282B1 (fr) *	1998-04-08	2001-04-20	Hoechst Marion Roussel Inc	Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
US6590083B1 (en)	1999-04-16	2003-07-08	Ortho-Mcneil Pharmaceutical, Inc.	Ketolide antibacterials
NZ515027A (en) *	1999-04-16	2004-01-30	Kosan Biosciences Inc	Erythromycin derivatives as antibiotics
EP1171447A2 (en)	1999-04-16	2002-01-16	Ortho-McNeil Pharmaceutical, Inc.	Ketolide antibacterials
GB0031312D0 (en) *	2000-12-21	2001-02-07	Glaxo Group Ltd	Macrolides
EP3738591A3 (en) *	2003-03-10	2021-03-24	Merck Sharp & Dohme Corp.	Novel antibacterial agents
WO2009055557A1 (en) *	2007-10-25	2009-04-30	Cempra Pharmaceuticals, Inc.	Process for the preparation of macrolide antibacterial agents
DK2358379T3 (en)	2008-10-24	2016-03-07	Cempra Pharmaceuticals Inc	BIOFORSVAR USING TRIAZOLHOLDIGE macrolides
US9937194B1 (en)	2009-06-12	2018-04-10	Cempra Pharmaceuticals, Inc.	Compounds and methods for treating inflammatory diseases
EP2475253B1 (en)	2009-09-10	2016-10-26	Cempra Pharmaceuticals, Inc.	Methods for treating malaria, tuberculosis and mac diseases
JP5711352B2 (ja)	2010-03-22	2015-04-30	センプラファーマシューティカルズ，インコーポレイテッド	マクロライドの結晶形、およびその使用
WO2011146829A1 (en)	2010-05-20	2011-11-24	Cempra Pharmaceuticals, Inc.	Processes for preparing macrolides and ketolides and intermediates therefor
US9815863B2 (en)	2010-09-10	2017-11-14	Cempra Pharmaceuticals, Inc.	Hydrogen bond forming fluoro ketolides for treating diseases
US10188674B2 (en)	2012-03-27	2019-01-29	Cempra Pharmaceuticals, Inc.	Parenteral formulations for administering macrolide antibiotics
EP2968801B1 (en)	2013-03-14	2018-09-26	Cempra Pharmaceuticals, Inc.	Methods for treating respiratory diseases and formulations therefor
CN105188712A (zh)	2013-03-15	2015-12-23	森普拉制药公司	用于制备大环内酯抗菌剂的收敛方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3923784A (en) *	1973-09-10	1975-12-02	Hoffmann La Roche	Erythromycin a derivatives
US4518590A (en) *	1984-04-13	1985-05-21	Pfizer Inc.	9α-Aza-9α-homoerythromycin compounds, pharmaceutical compositions and therapeutic method
US4742049A (en) *	1986-06-04	1988-05-03	Abbott Laboratories	Semisynthetic erythromycin antibiotics
PT86800B (pt) *	1987-02-24	1992-05-29	Beecham Group Plc	Processo para a preparacao de derivados de eritromicina
US5523399A (en) *	1991-12-27	1996-06-04	Taisho Pharmaceutical Co., Ltd.	5-O-desosaminylerythronolide derivatives
AU662420B2 (en) *	1992-04-22	1995-08-31	Taisho Pharmaceutical Co., Ltd.	5-O-desosaminylerythronolide A derivative
FR2692579B1 (fr) *	1992-06-19	1995-06-02	Roussel Uclaf	Nouveaux dérivés de la picromycine, leur procédé de préparation et leur application comme médicaments.
US5602239A (en) *	1993-01-26	1997-02-11	Taisho Pharmaceutical Co., Ltd.	5-O-desosaminylerythronolide derivatives

1995
- 1995-10-09 FR FR9511861A patent/FR2739620B1/fr not_active Expired - Fee Related
1996
- 1996-08-06 ZA ZA9606666A patent/ZA966666B/xx unknown
- 1996-08-10 UA UA98041836A patent/UA52621C2/uk unknown
- 1996-10-07 AR ARP960104634A patent/AR004688A1/es not_active Application Discontinuation
- 1996-10-08 CN CN96197514A patent/CN1067401C/zh not_active Expired - Lifetime
- 1996-10-08 AT AT96933501T patent/ATE212034T1/de active
- 1996-10-08 TR TR1998/00624T patent/TR199800624T1/xx unknown
- 1996-10-08 KR KR10-1998-0702581A patent/KR100451063B1/ko not_active Expired - Lifetime
- 1996-10-08 EP EP96933501A patent/EP0854879B1/fr not_active Expired - Lifetime
- 1996-10-08 US US09/051,378 patent/US6011142A/en not_active Ceased
- 1996-10-08 PL PL96326001A patent/PL183645B1/pl not_active IP Right Cessation
- 1996-10-08 CA CA002231562A patent/CA2231562C/fr not_active Expired - Lifetime
- 1996-10-08 BR BR9610959A patent/BR9610959A/pt not_active Application Discontinuation
- 1996-10-08 SI SI9630452T patent/SI0854879T1/xx unknown
- 1996-10-08 CZ CZ19981055A patent/CZ293430B6/cs not_active IP Right Cessation
- 1996-10-08 DE DE69618607T patent/DE69618607T2/de not_active Expired - Lifetime
- 1996-10-08 AP APAP/P/1998/001216A patent/AP888A/en active
- 1996-10-08 AU AU72208/96A patent/AU708351B2/en not_active Expired
- 1996-10-08 WO PCT/FR1996/001567 patent/WO1997013774A2/fr not_active Ceased
- 1996-10-08 EE EE9800109A patent/EE03878B1/et not_active IP Right Cessation
- 1996-10-08 SK SK431-98A patent/SK283619B6/sk unknown
- 1996-10-08 EA EA199800280A patent/EA000765B1/ru not_active IP Right Cessation
- 1996-10-08 PT PT96933501T patent/PT854879E/pt unknown
- 1996-10-08 HU HU9900136A patent/HUP9900136A3/hu unknown
- 1996-10-08 GE GEAP19964227A patent/GEP20032899B/en unknown
- 1996-10-08 IL IL12361396A patent/IL123613A0/xx not_active IP Right Cessation
- 1996-10-08 DK DK96933501T patent/DK0854879T3/da active
- 1996-10-08 RO RO98-00826A patent/RO118874B1/ro unknown
- 1996-10-08 ES ES96933501T patent/ES2171722T3/es not_active Expired - Lifetime
- 1996-10-08 JP JP51476697A patent/JP4327248B2/ja not_active Expired - Lifetime
1998
- 1998-03-25 BG BG102350A patent/BG63752B1/bg unknown
- 1998-04-03 MX MX9802655A patent/MX9802655A/es unknown
- 1998-04-08 NO NO19981630A patent/NO312592B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
JPH11513401A (ja)	1999-11-16
SK283619B6 (sk)	2003-10-07
BG63752B1 (bg)	2002-11-29
DK0854879T3 (da)	2002-05-06
SI0854879T1 (en)	2002-08-31
CN1067401C (zh)	2001-06-20
GEP20032899B (en)	2003-02-25
HUP9900136A3 (en)	2000-04-28
PL183645B1 (pl)	2002-06-28
PL326001A1 (en)	1998-08-17
DE69618607T2 (de)	2002-08-14
SK43198A3 (en)	1998-11-04
FR2739620A1 (fr)	1997-04-11
HUP9900136A1 (hu)	1999-05-28
CZ293430B6 (cs)	2004-04-14
NO981630D0 (no)	1998-04-08
EA199800280A1 (ru)	1998-10-29
NO312592B1 (no)	2002-06-03
ZA966666B (en)	1997-08-06
AP888A (en)	2000-11-10
WO1997013774A3 (fr)	1997-05-29
IL123613A0 (en)	1998-10-30
ES2171722T3 (es)	2002-09-16
AU7220896A (en)	1997-04-30
EE9800109A (et)	1998-10-15
TR199800624T1 (xx)	1998-06-22
CA2231562C (fr)	2006-11-28
BG102350A (en)	1999-03-31
DE69618607D1 (de)	2002-02-21
EP0854879A2 (fr)	1998-07-29
CZ105598A3 (cs)	1998-07-15
US6011142A (en)	2000-01-04
WO1997013774A2 (fr)	1997-04-17
KR19990064100A (ko)	1999-07-26
AR004688A1 (es)	1999-03-10
MX9802655A (es)	1998-11-30
EP0854879B1 (fr)	2002-01-16
ATE212034T1 (de)	2002-02-15
PT854879E (pt)	2002-07-31
BR9610959A (pt)	1999-03-02
FR2739620B1 (fr)	1997-12-19
CA2231562A1 (fr)	1997-04-17
JP4327248B2 (ja)	2009-09-09
AU708351B2 (en)	1999-08-05
NO981630L (no)	1998-04-08
KR100451063B1 (ko)	2004-12-17
EA000765B1 (ru)	2000-04-24
CN1199403A (zh)	1998-11-18
RO118874B1 (ro)	2003-12-30
UA52621C2 (uk)	2003-01-15

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Legal Events

Date	Code	Title	Description
2003-02-17	KB4A	Valid patent at the end of a year	Effective date: 20021231
2004-02-16	KB4A	Valid patent at the end of a year	Effective date: 20031231
2004-12-15	GB1A	Change in the ownership or in the address of the owner
2005-02-15	KB4A	Valid patent at the end of a year	Effective date: 20041231
2006-02-15	KB4A	Valid patent at the end of a year	Effective date: 20051231
2007-02-15	KB4A	Valid patent at the end of a year	Effective date: 20061231
2007-06-15	MM4A	Lapsed by not paying the annual fees	Effective date: 20061008