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FI971953L - Proteiinityrosiinikinaasin välittämää soluproliferaatiota inhiboivat 6-aryyli-pyrido(2,3-d)pyrimidiinit ja naftyridiinit - Google Patents

Proteiinityrosiinikinaasin välittämää soluproliferaatiota inhiboivat 6-aryyli-pyrido(2,3-d)pyrimidiinit ja naftyridiinit Download PDF

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Publication number
FI971953L
FI971953L FI971953A FI971953A FI971953L FI 971953 L FI971953 L FI 971953L FI 971953 A FI971953 A FI 971953A FI 971953 A FI971953 A FI 971953A FI 971953 L FI971953 L FI 971953L
Authority
FI
Finland
Prior art keywords
naphthyridines
pyrido
pyrimidines
inhibited
aryl
Prior art date
Application number
FI971953A
Other languages
English (en)
Swedish (sv)
Other versions
FI971953A7 (fi
FI971953A0 (fi
Inventor
Clifton John Blankley
Annette Marian Doherty
James Marino Hamby
Robert Lee Panek
Mel Conrad Schroeder
Howard Daniel Hollis Showalter
Cleo Connolly
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/539,410 external-priority patent/US5733913A/en
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of FI971953A0 publication Critical patent/FI971953A0/fi
Publication of FI971953L publication Critical patent/FI971953L/fi
Publication of FI971953A7 publication Critical patent/FI971953A7/fi

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/16Emollients or protectives, e.g. against radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Vascular Medicine (AREA)
  • Toxicology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyridine Compounds (AREA)
FI971953A 1994-11-14 1995-11-13 Proteiinityrosiinikinaasin välittämää soluproliferaatiota inhiboivat 6 -aryyli-pyrido(2,3-d)pyrimidiinit ja naftyridiinit FI971953A7 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US33905194A 1994-11-14 1994-11-14
US08/539,410 US5733913A (en) 1994-11-14 1995-11-06 6-Aryl pyrido 2,3-d! pyrimidines and naphthyridines for inhibiting protein tyrosine kinase mediated cellular proliferation
PCT/US1995/014700 WO1996015128A2 (en) 1994-11-14 1995-11-13 6-ARYL PYRIDO[2,3-d]PYRIMIDINES AND NAPHTHYRIDINES FOR INHIBITING PROTEIN TYROSINE KINASE MEDIATED CELLULAR PROLIFERATION

Publications (3)

Publication Number Publication Date
FI971953A0 FI971953A0 (fi) 1997-05-07
FI971953L true FI971953L (fi) 1997-05-12
FI971953A7 FI971953A7 (fi) 1997-05-12

Family

ID=26991470

Family Applications (1)

Application Number Title Priority Date Filing Date
FI971953A FI971953A7 (fi) 1994-11-14 1995-11-13 Proteiinityrosiinikinaasin välittämää soluproliferaatiota inhiboivat 6 -aryyli-pyrido(2,3-d)pyrimidiinit ja naftyridiinit

Country Status (25)

Country Link
US (1) US5952342A (fi)
EP (1) EP0790997B1 (fi)
CN (1) CN1085666C (fi)
AT (1) ATE190978T1 (fi)
AU (1) AU711426B2 (fi)
BG (1) BG63162B1 (fi)
CZ (1) CZ286160B6 (fi)
DE (1) DE69515898T2 (fi)
DK (1) DK0790997T3 (fi)
ES (1) ES2146782T3 (fi)
FI (1) FI971953A7 (fi)
GE (1) GEP20012444B (fi)
GR (1) GR3033439T3 (fi)
HU (1) HUT76853A (fi)
IL (1) IL115970A (fi)
MD (1) MD1861G2 (fi)
MX (1) MX9702245A (fi)
NO (1) NO308250B1 (fi)
NZ (1) NZ296456A (fi)
PL (1) PL181893B1 (fi)
PT (1) PT790997E (fi)
RU (1) RU2191188C2 (fi)
SK (1) SK281724B6 (fi)
TJ (1) TJ342B (fi)
WO (1) WO1996015128A2 (fi)

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DK172753B1 (da) * 1988-05-25 1999-06-28 Lilly Co Eli N-(5,6,7,8-tetrahydropyrido[2,3--d]pyrimidin-6-yl-alkanoyl)-glutaminsyrederivater, deres anvendelse, farmaceutiske præparat
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MX9702245A (es) 1997-06-28
CZ286160B6 (cs) 2000-01-12
DE69515898T2 (de) 2000-08-17
GR3033439T3 (en) 2000-09-29
NO308250B1 (no) 2000-08-21
ATE190978T1 (de) 2000-04-15
MD1861F2 (en) 2002-02-28
ES2146782T3 (es) 2000-08-16
HUT76853A (en) 1997-12-29
NO972198L (no) 1997-05-13
WO1996015128A3 (en) 1996-07-11
FI971953A7 (fi) 1997-05-12
PL181893B1 (pl) 2001-10-31
SK281724B6 (sk) 2001-07-10
MD1861G2 (ro) 2002-09-30
EP0790997B1 (en) 2000-03-22
GEP20012444B (en) 2001-05-25
BG101326A (bg) 1998-04-30
PT790997E (pt) 2000-06-30
CN1169726A (zh) 1998-01-07
WO1996015128A2 (en) 1996-05-23
CZ139097A3 (cs) 1998-02-18
TJ342B (en) 2002-10-06
RU2191188C2 (ru) 2002-10-20
NO972198D0 (no) 1997-05-13
PL320169A1 (en) 1997-09-15
AU4107896A (en) 1996-06-06
DK0790997T3 (da) 2000-08-21
IL115970A0 (en) 1996-01-31
SK60997A3 (en) 1998-05-06
AU711426B2 (en) 1999-10-14
EP0790997A2 (en) 1997-08-27
FI971953A0 (fi) 1997-05-07
CN1085666C (zh) 2002-05-29
US5952342A (en) 1999-09-14
NZ296456A (en) 1999-09-29
MD970187A (en) 1999-02-28
BG63162B1 (bg) 2001-05-31
IL115970A (en) 1999-06-20
DE69515898D1 (de) 2000-04-27

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