FI971711L - Levobupivakaiinin ja sen analogien kiteyttäminen - Google Patents

Levobupivakaiinin ja sen analogien kiteyttäminen Download PDF

Info

Publication number: FI971711L
Authority: FI; Finland
Prior art keywords: levobupivacaine; analogues; crystallization
Prior art date: 1994-10-25

Application number

FI971711A

Other languages

English (en)

Swedish (sv)

Other versions

FI971711A0 (fi

FI117438B (fi

Inventor

Marianne Langston

Benjamin Mark Skead

Original Assignee

Chiroscience Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-10-25

Filing date

1997-04-22

Publication date

1997-04-22

1994-10-25 Priority claimed from GB9421476A external-priority patent/GB9421476D0/en

1995-03-10 Priority claimed from GBGB9504926.8A external-priority patent/GB9504926D0/en

1997-04-22 Application filed by Chiroscience Ltd filed Critical Chiroscience Ltd

1997-04-22 Publication of FI971711L publication Critical patent/FI971711L/fi

1997-04-22 Publication of FI971711A0 publication Critical patent/FI971711A0/fi

2006-10-13 Application granted granted Critical

2006-10-13 Publication of FI117438B publication Critical patent/FI117438B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Hydrogenated Pyridines (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Epoxy Compounds (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Saccharide Compounds (AREA)
Non-Silver Salt Photosensitive Materials And Non-Silver Salt Photography (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Compounds Of Unknown Constitution (AREA)
Investigating Or Analysing Biological Materials (AREA)

FI971711A 1994-10-25 1997-04-22 Menetelmä optisesti rikastetun bupivakaiinin valmistamiseksi FI117438B (fi)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
GB9421476		1994-10-25
GB9421476A GB9421476D0 (en)	1994-10-25	1994-10-25	Process and salt
GBGB9504926.8A GB9504926D0 (en)	1995-03-10	1995-03-10	Crystallisation
GB9504926		1995-03-10
GB9502513		1995-10-23
PCT/GB1995/002513 WO1996012699A1 (en)	1994-10-25	1995-10-23	Crystallisation of levobupivacaine and analogues thereof

Publications (3)

Publication Number	Publication Date
FI971711L true FI971711L (fi)	1997-04-22
FI971711A0 FI971711A0 (fi)	1997-04-22
FI117438B FI117438B (fi)	2006-10-13

Family

ID=26305863

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI971711A FI117438B (fi)	1994-10-25	1997-04-22	Menetelmä optisesti rikastetun bupivakaiinin valmistamiseksi

Country Status (16)

Country	Link
US (1)	US5994548A (fi)
EP (1)	EP0788480B1 (fi)
JP (1)	JP3911545B2 (fi)
AT (1)	ATE245629T1 (fi)
AU (1)	AU698637B2 (fi)
CA (1)	CA2200355C (fi)
DE (1)	DE69531356T2 (fi)
DK (1)	DK0788480T3 (fi)
ES (1)	ES2202375T3 (fi)
FI (1)	FI117438B (fi)
HU (1)	HU227420B1 (fi)
MX (1)	MX9703024A (fi)
NO (1)	NO309266B1 (fi)
PL (1)	PL183210B1 (fi)
PT (1)	PT788480E (fi)
WO (1)	WO1996012699A1 (fi)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
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BR0002246A (pt) *	2000-04-06	2003-04-15	Cristalia Prod Quimicos Farm	Processo de obtenção dos enantiÈmeros da bupivacaìna racêmica, processo de obtenção de composições farmacêuticas a base de levobupivacaìna: composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis e utilização das composições farmacêuticas a base de levobupivacaìna formuladas nas formas básicas ou sais farmaceuticamente aceitáveis
BRPI0104491B8 (pt) *	2001-10-10	2021-05-25	Cristalia Produtos Quim Farmaceuticos Ltda	n-(2,6-dimetilfenil)-1-propil-2-piperidinocarboxamida; processo de obtenção dos enantiômeros; mistura não racêmica dos anantiômeros e seu processo de obtenção e composição farmacêutica.
US20040001889A1 (en)	2002-06-25	2004-01-01	Guohua Chen	Short duration depot formulations
CN101797221B (zh)	2002-12-13	2013-06-12	杜雷科特公司	包含高粘度液体载体材料的口服递药系统
US7094812B2 (en) *	2003-04-24	2006-08-22	Xerox Corporations	Colorant compositions
US6790267B1 (en) *	2003-04-24	2004-09-14	Xerox Corporation	Colorant compositions
HUE032040T2 (en)	2004-09-17	2017-09-28	Durect Corp	Saib-containing (sucrose acetate-isobutyrate) sustained-release local anesthetic composition
US20070027105A1 (en)	2005-07-26	2007-02-01	Alza Corporation	Peroxide removal from drug delivery vehicle
EP2010491A1 (en) *	2006-04-25	2009-01-07	Disham Pharmaceuticals and Chemicals Ltd.	Ropivacaine hydrochloride anhydrate and the preparation thereof
US8337883B2 (en)	2006-11-03	2012-12-25	Durect Corporation	Transdermal delivery systems
AU2008335809A1 (en)	2007-12-06	2009-06-18	Durect Corporation	Methods useful for the treatment of pain, arthritic conditions, or inflammation associated with a chronic condition
PL2234974T3 (pl) *	2008-01-15	2012-09-28	Pharmathen Sa	Sposób otrzymywania związku (s)-1-alkilo-2', 6'-pipekoloksylidydu
US20100260844A1 (en)	2008-11-03	2010-10-14	Scicinski Jan J	Oral pharmaceutical dosage forms
CN103073484B (zh) *	2013-01-28	2014-10-22	山东诚创医药技术开发有限公司	一种甲哌卡因及其光学对映体的制备方法
WO2014144975A1 (en)	2013-03-15	2014-09-18	Durect Corporation	Compositions with a rheological modifier to reduce dissolution variability
CA3028450A1 (en)	2016-07-06	2018-01-11	Durect Corporation	Oral dosage form with drug composition, barrier layer and drug layer
KR102422382B1 (ko) *	2016-12-26	2023-01-25	셀릭스 바이오 프라이빗 리미티드	통증 치료를 위한 조성물
WO2021146215A1 (en)	2020-01-13	2021-07-22	Durect Corporation	Sustained release drug delivery systems with reduced impurities and related methods
JP2024503402A (ja)	2021-01-12	2024-01-25	デュレクトコーポレーション	徐放性薬物送達システム及び関連の方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
SE341404B (fi) *	1967-05-18	1971-12-27	Sterling Drug Inc
US4695576A (en) *	1984-07-09	1987-09-22	Astra Lake Medel Aktiebolag	L-N-n-propylpipecolic acid-2,6-xylidide

1995
- 1995-10-23 MX MX9703024A patent/MX9703024A/es unknown
- 1995-10-23 HU HU9702372A patent/HU227420B1/hu unknown
- 1995-10-23 CA CA002200355A patent/CA2200355C/en not_active Expired - Lifetime
- 1995-10-23 DE DE69531356T patent/DE69531356T2/de not_active Expired - Lifetime
- 1995-10-23 WO PCT/GB1995/002513 patent/WO1996012699A1/en not_active Ceased
- 1995-10-23 AT AT95934738T patent/ATE245629T1/de active
- 1995-10-23 EP EP95934738A patent/EP0788480B1/en not_active Expired - Lifetime
- 1995-10-23 PL PL95319829A patent/PL183210B1/pl unknown
- 1995-10-23 ES ES95934738T patent/ES2202375T3/es not_active Expired - Lifetime
- 1995-10-23 US US08/849,418 patent/US5994548A/en not_active Expired - Lifetime
- 1995-10-23 AU AU37048/95A patent/AU698637B2/en not_active Expired
- 1995-10-23 DK DK95934738T patent/DK0788480T3/da active
- 1995-10-23 PT PT95934738T patent/PT788480E/pt unknown
- 1995-10-23 JP JP51373896A patent/JP3911545B2/ja not_active Expired - Lifetime
1997
- 1997-04-22 FI FI971711A patent/FI117438B/fi not_active IP Right Cessation
- 1997-04-24 NO NO971903A patent/NO309266B1/no not_active IP Right Cessation

Also Published As

Publication number	Publication date
NO309266B1 (no)	2001-01-08
HUT77631A (hu)	1998-06-29
DE69531356D1 (de)	2003-08-28
US5994548A (en)	1999-11-30
AU698637B2 (en)	1998-11-05
EP0788480B1 (en)	2003-07-23
FI971711A0 (fi)	1997-04-22
DE69531356T2 (de)	2004-05-27
JP3911545B2 (ja)	2007-05-09
PT788480E (pt)	2003-12-31
EP0788480A1 (en)	1997-08-13
CA2200355A1 (en)	1996-05-02
NO971903L (no)	1997-04-24
NO971903D0 (no)	1997-04-24
HU227420B1 (en)	2011-05-30
WO1996012699A1 (en)	1996-05-02
JPH10507464A (ja)	1998-07-21
PL319829A1 (en)	1997-09-01
AU3704895A (en)	1996-05-15
ES2202375T3 (es)	2004-04-01
ATE245629T1 (de)	2003-08-15
CA2200355C (en)	2007-03-06
DK0788480T3 (da)	2003-09-29
PL183210B1 (pl)	2002-06-28
FI117438B (fi)	2006-10-13
MX9703024A (es)	1997-10-31

Publication	Publication Date	Title
FI971711L (fi)	1997-04-22	Levobupivakaiinin ja sen analogien kiteyttäminen
FI973750A7 (fi)	1997-09-22	2-metyylitienobentsodiatsepiinin valmistus ja kiteiset muodot
EE200000725A (et)	2002-06-17	Uued 3-arüülpropaanhappe derivaadid ja nende analoogid
FI941787A7 (fi)	1994-10-20	Sähkökirurginen prosessori ja menetelmä sen käyttämiseksi
BR8901250A (pt)	1989-11-07	Composicao oral e processo de inibir calculo dental
FI961599A7 (fi)	1996-06-07	1N-alkyyli-N-aryylipyrimidiiniamiineja ja niiden johdannaisia
NO952357D0 (no)	1995-06-14	Formulering av insulinanaloger
FI944310A7 (fi)	1995-03-18	Heteroaryyliamino- ja heteroaryylisuolfonamidosubstituoituja 3-bentsyyliaminometyylipiperidiinejä ja vastaavia yhdisteitä
FI900412A7 (fi)	1990-01-25	Viruksen- tai bakteerinvastainen yhdiste ja menetelmä sen käyttämiseks i
FI960635A7 (fi)	1996-02-12	Elektrodi ja sen valmistus
FI945434L (fi)	1994-11-18	4-markatpoasetyyliamino/2/bentsatsepinoni (3) johdannaisia ja niiden käyttö enkefalinaasi-inhibiittoreina
FI950379L (fi)	1995-01-27	Omepratsolia ja sen analogeja sisältävä injektio ja injektiopakkaus
FI972865L (fi)	1997-09-03	Hydroksimetyyli-imidatsodiatseptiinejä ja niiden esterit
BR8804335A (pt)	1989-05-23	Implante oral e processo de fixar o mesmo
FI971495L (fi)	1997-06-10	Vaahdonestokoostumus ja sen käyttömenetelmä
FI971202L (fi)	1997-03-21	Levobupivakaiinin ja sen analogien valmistuksessa käytettäviä menetelmiä rasemisoinnin ja asymmetrisen muuntamisen tekemiseksi
FI935728L (fi)	1994-06-22	Substituoituja 4-fenyylipyridoneja ja 4-fenyyli-2-alkoksipyridiinejä
FI971750A0 (fi)	1997-04-24	Koostumuksia multippeliskleroosia varten ja sen hoito
FI934986A7 (fi)	1994-05-13	Lantaanin avulla stabiloitu alumiinioksidi ja sen valmistusmenetelmä
FI980246A0 (fi)	1998-02-04	Menetelmä keittimen käyttämiseksi ja keitin
FI954220L (fi)	1996-03-13	Yhdistelmä-mersasidiini ja sen valmistusmenetelmä
DE69324288D1 (de)	1999-05-12	Beschleunigung- und Winkelbeschleunigungsmesser
FI945427A7 (fi)	1995-01-18	Dynemisiinianalogien enantiomeerit, niiden valmistus ja käyttö
FI963325L (fi)	1996-10-21	Inhibiinikoostumukset ja menetelmät niiden käyttämiseksi
BR9306359A (pt)	1998-06-30	Azocorantes aplicação do azocorante e modificação cristalina

Legal Events

Date	Code	Title	Description
2006-10-13	FG	Patent granted	Ref document number: 117438 Country of ref document: FI
2015-11-18	MA	Patent expired

Date

Code

Title

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2006-10-13

Patent granted

Ref document number: 117438

Country of ref document: FI

2015-11-18

Patent expired