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FI970598L - Nukeliinihappoihin sekvenssipesifisesti sitoutuvat oligomeerit ja niiden käyttö antisense-menetelmissä - Google Patents

Nukeliinihappoihin sekvenssipesifisesti sitoutuvat oligomeerit ja niiden käyttö antisense-menetelmissä Download PDF

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Publication number
FI970598L
FI970598L FI970598A FI970598A FI970598L FI 970598 L FI970598 L FI 970598L FI 970598 A FI970598 A FI 970598A FI 970598 A FI970598 A FI 970598A FI 970598 L FI970598 L FI 970598L
Authority
FI
Finland
Prior art keywords
oligomers
specifically
nucleic acids
antisense methods
bind sequence
Prior art date
Application number
FI970598A
Other languages
English (en)
Swedish (sv)
Other versions
FI970598A7 (fi
FI970598A0 (fi
Inventor
Piet Herdewijn
Aerschot Arthur Van
Original Assignee
Stichting Rega V Z W
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stichting Rega V Z W filed Critical Stichting Rega V Z W
Publication of FI970598A7 publication Critical patent/FI970598A7/fi
Publication of FI970598L publication Critical patent/FI970598L/fi
Publication of FI970598A0 publication Critical patent/FI970598A0/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C07F9/65586Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system at least one of the hetero rings does not contain nitrogen as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI970598A 1994-08-17 1995-08-14 Nukeliinihappoihin sekvenssipesifisesti sitoutuvat oligomeerit ja niiden käyttö antisense-menetelmissä FI970598A0 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP94202342 1994-08-17
US49515295A 1995-06-27 1995-06-27
PCT/EP1995/003248 WO1996005213A1 (en) 1994-08-17 1995-08-14 Sequence-specific binding oligomers for nucleic acids and their use in antisense strategies

Publications (3)

Publication Number Publication Date
FI970598A7 FI970598A7 (fi) 1997-02-12
FI970598L true FI970598L (fi) 1997-02-12
FI970598A0 FI970598A0 (fi) 1997-02-12

Family

ID=26136490

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970598A FI970598A0 (fi) 1994-08-17 1995-08-14 Nukeliinihappoihin sekvenssipesifisesti sitoutuvat oligomeerit ja niiden käyttö antisense-menetelmissä

Country Status (10)

Country Link
EP (1) EP0777676A1 (fi)
JP (1) JP2000505778A (fi)
CN (1) CN1158618A (fi)
AU (1) AU3384595A (fi)
CA (1) CA2196306A1 (fi)
FI (1) FI970598A0 (fi)
HU (1) HUT77509A (fi)
NO (1) NO970716L (fi)
NZ (1) NZ292140A (fi)
WO (1) WO1996005213A1 (fi)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1874397A (en) * 1996-02-16 1997-09-02 Stichting Rega Vzw Hexitol containing oligonucleotides and their use in antisense strategies
US7205106B1 (en) 2001-07-20 2007-04-17 Roche Molecular Systems, Inc. Association of polymorphisms in IL4-related genes with autoimmune disease
WO2003057910A2 (en) 2002-01-08 2003-07-17 Roche Diagnostics Gmbh Use of silica material in an amplification reaction
ATE319699T1 (de) * 2002-12-20 2006-03-15 Hoffmann La Roche Mannitol- und glucitolderivate
US7560231B2 (en) 2002-12-20 2009-07-14 Roche Molecular Systems, Inc. Mannitol and glucitol derivatives
EP1431297A1 (en) * 2002-12-20 2004-06-23 Boehringer Mannheim Gmbh Mannitol and glucitol derivatives
CA2463719A1 (en) 2003-04-05 2004-10-05 F. Hoffmann-La Roche Ag Nucleotide analogs with six membered rings
EP1466919A1 (en) * 2003-04-05 2004-10-13 Roche Diagnostics GmbH Nucleotide analogs with six membered rings
WO2006047842A2 (en) * 2004-11-08 2006-05-11 K.U. Leuven Research And Development Modified nucleosides for rna interference
EP2265627A2 (en) * 2008-02-07 2010-12-29 Isis Pharmaceuticals, Inc. Bicyclic cyclohexitol nucleic acid analogs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL9300058A (nl) * 1992-06-18 1994-01-17 Stichting Rega V Z W 1,5-anhydrohexitol nucleoside analoga en farmaceutisch gebruik daarvan.
US5314893A (en) * 1993-01-25 1994-05-24 Bristol-Myers Squibb Co. Antiviral tetrahydropyrans

Also Published As

Publication number Publication date
FI970598A7 (fi) 1997-02-12
CN1158618A (zh) 1997-09-03
WO1996005213A1 (en) 1996-02-22
JP2000505778A (ja) 2000-05-16
MX9701111A (es) 1998-03-31
HUT77509A (hu) 1998-05-28
CA2196306A1 (en) 1996-02-22
NO970716L (no) 1997-02-17
EP0777676A1 (en) 1997-06-11
FI970598A0 (fi) 1997-02-12
AU3384595A (en) 1996-03-07
NZ292140A (en) 1998-02-26

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