FI963004A0 - Vasta-aineen muodostumista kiihottavia monoklonaalivasta-aineita - Google Patents

Vasta-aineen muodostumista kiihottavia monoklonaalivasta-aineita

Info

Publication number: FI963004A0
Authority: FI; Finland
Prior art keywords: monoclonal antibodies; immunostimulatory activity; tumor; elicts; immuno
Prior art date: 1994-01-31

Application number

FI963004A

Other languages

English (en)

Swedish (sv)

Other versions

FI963004A7 (fi

FI963004L (fi

Inventor

Britta Hardy

Avraham Novogrodsky

Original Assignee

Mor Research Applic Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1994-01-31

Filing date

1995-01-30

Publication date

1996-07-29

1995-01-30 Application filed by Mor Research Applic Ltd filed Critical Mor Research Applic Ltd

1996-07-29 Publication of FI963004A0 publication Critical patent/FI963004A0/fi

1996-09-27 Publication of FI963004A7 publication Critical patent/FI963004A7/fi

1996-09-27 Publication of FI963004L publication Critical patent/FI963004L/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Immunology (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Cell Biology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Animal Behavior & Ethology (AREA)
Toxicology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)
Detergent Compositions (AREA)

FI963004A 1994-01-31 1995-01-30 Vasta-aineen muodostumista kiihottavia monoklonaalivasta-aineita FI963004L (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
IL10850194A IL108501A (en)	1994-01-31	1994-01-31	Antibodies and pharmaceutical compositions containing them
PCT/US1995/001137 WO1995020605A1 (en)	1994-01-31	1995-01-30	Immuno-stimulatory monoclonal antibodies

Publications (3)

Publication Number	Publication Date
FI963004A0 true FI963004A0 (fi)	1996-07-29
FI963004A7 FI963004A7 (fi)	1996-09-27
FI963004L FI963004L (fi)	1996-09-27

Family

ID=11065761

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI963004A FI963004L (fi)	1994-01-31	1995-01-30	Vasta-aineen muodostumista kiihottavia monoklonaalivasta-aineita

Country Status (20)

Country	Link
US (1)	US5897862A (fi)
EP (1)	EP0742795B1 (fi)
JP (1)	JP3478398B2 (fi)
CN (1)	CN1052733C (fi)
AT (1)	ATE171461T1 (fi)
AU (1)	AU693526B2 (fi)
CA (1)	CA2182289C (fi)
DE (1)	DE69504955T2 (fi)
DK (1)	DK0742795T3 (fi)
EE (1)	EE03285B1 (fi)
ES (1)	ES2124533T3 (fi)
FI (1)	FI963004L (fi)
IL (1)	IL108501A (fi)
LT (1)	LT4225B (fi)
LV (1)	LV11624B (fi)
MD (1)	MD1374G2 (fi)
MX (1)	MX9603080A (fi)
NO (1)	NO317020B1 (fi)
RU (1)	RU2155190C2 (fi)
WO (1)	WO1995020605A1 (fi)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2145634C1 (ru) *	1998-03-12	2000-02-20	Булычева Татьяна Ивановна	Штамм культивируемых клеток мышиной гибридомы, используемый для получения моноклональных антител к ядрышковому антигену, ассоциированному с клеточной пролиферацией
IL129299A0 (en)	1999-03-31	2000-02-17	Mor Research Applic Ltd	Monoclonal antibodies antigens and diagnosis of malignant diseases
RU2192888C1 (ru) *	2001-02-15	2002-11-20	Эпштейн Олег Ильич	Лекарственное средство и способ лечения патологического синдрома
CN1294148C (zh) *	2001-04-11	2007-01-10	中国科学院遗传与发育生物学研究所	环状单链三特异抗体
IL145926A0 (en)	2001-10-15	2002-07-25	Mor Research Applic Ltd	Peptide epitopes of mimotopes useful in immunomodulation
IL149820A0 (en)	2002-05-23	2002-11-10	Curetech Ltd	Humanized immunomodulatory monoclonal antibodies for the treatment of neoplastic disease or immunodeficiency
EP2243493A1 (en)	2002-07-03	2010-10-27	Ono Pharmaceutical Co., Ltd.	Immunopotentiative composition
DE10311248A1 (de) *	2003-03-14	2004-09-30	Müller-Hermelink, Hans Konrad, Prof. Dr.	Humaner monoklonaler Antikörper
DK1673397T3 (da) *	2003-07-02	2011-03-07	Univ Genova	Fremgangsmåde til fremstilling og evaluering af cytotoksicitet af KIR2DL NK-receptorer antistoffer
US20090123413A1 (en) *	2004-08-23	2009-05-14	Britta Hardy	Use of bat monoclonal antibody for immunotherapy
MX2007013978A (es)	2005-05-09	2008-02-22	Ono Pharmaceutical Co	Anticuerpos monoclonales humanos a muerte programada 1 (pd-1) y metodos para tratamiento de cancer utilizando anticuerpos anti-pd-1 solos o en combinacion con otros inmunoterapeuticos.
CN105330741B (zh)	2005-07-01	2023-01-31	E.R.施贵宝&圣斯有限责任公司	抗程序性死亡配体1(pd-l1)的人单克隆抗体
KR101562580B1 (ko) *	2007-06-18	2015-10-22	머크 샤프 앤 도메 비.브이.	사람 프로그램된 사멸 수용체 ｐｄ-1에 대한 항체
ES2639857T3 (es) *	2008-02-11	2017-10-30	Cure Tech Ltd.	Anticuerpos monoclonales para el tratamiento del tumor
MD3972C2 (ro) *	2009-03-11	2010-07-31	Ион МЕРЕУЦЭ	Remediu şi metodă de tratament al stărilor precanceroase
BR112013032552A2 (pt)	2011-07-24	2017-12-12	Curetech Ltd	variantes de anticorpos monoclonais humanizados imunomoduladores
US10570204B2 (en)	2013-09-26	2020-02-25	The Medical College Of Wisconsin, Inc.	Methods for treating hematologic cancers
US9580504B1 (en)	2013-11-07	2017-02-28	Curetech Ltd.	Pidilizumab monoclonal antibody therapy following stem cell transplantation
JOP20200094A1 (ar)	2014-01-24	2017-06-16	Dana Farber Cancer Inst Inc	جزيئات جسم مضاد لـ pd-1 واستخداماتها
JOP20200096A1 (ar)	2014-01-31	2017-06-16	Children’S Medical Center Corp	جزيئات جسم مضاد لـ tim-3 واستخداماتها
PH12016501545B1 (en)	2014-03-14	2023-12-06	Immutep Sas	Antibody molecules to lag-3 and uses thereof
TWI693232B (zh)	2014-06-26	2020-05-11	美商宏觀基因股份有限公司	與pd-1和lag-3具有免疫反應性的共價結合的雙抗體和其使用方法
CN107206071A (zh)	2014-09-13	2017-09-26	诺华股份有限公司	Alk抑制剂的联合疗法
TWI773646B (zh)	2015-06-08	2022-08-11	美商宏觀基因股份有限公司	結合lag-3的分子和其使用方法
GEAP202215554A (en)	2015-07-30	2022-06-10	Macrogenics Inc	Pd-1-binding molecules and methods of use thereof
HK1257840A1 (zh)	2015-09-01	2019-11-01	Agenus Inc.	抗-pd-1抗体及其使用方法
AU2016332725A1 (en)	2015-09-29	2018-03-22	Celgene Corporation	PD-1 binding proteins and methods of use thereof
JP2019500893A (ja)	2015-11-03	2019-01-17	ヤンセンバイオテツク，インコーポレーテツド	Ｐｄ−１及びｔｉｍ−３に特異的に結合する抗体及びそれらの使用
MX2018007089A (es)	2015-12-14	2019-01-30	Macrogenics Inc	Moleculas biespecificas que tienen inmunorreactividad con pd-1 y ctla-4, y metodos de uso de las mismas.
BR112018076281A2 (pt)	2016-06-20	2019-03-26	Kymab Limited	imunocitocina, uso de uma imunocitocina, método, composição farmacêutica, método para tratar uma doença proliferativa em um animal, ácido nucleico, vetor, hospedeiro e anticorpo ou fragmento do mesmo
JP2019534859A (ja)	2016-09-19	2019-12-05	セルジーンコーポレイション	Ｐｄ−１結合タンパク質を使用して白斑を治療する方法
SG11201901950TA (en)	2016-09-19	2019-04-29	Celgene Corp	Methods of treating immune disorders using pd-1 binding proteins
CA3046082A1 (en)	2016-12-07	2018-06-14	Agenus Inc.	Antibodies and methods of use thereof
US12398209B2 (en)	2018-01-22	2025-08-26	Janssen Biotech, Inc.	Methods of treating cancers with antagonistic anti-PD-1 antibodies
GB202107994D0 (en)	2021-06-04	2021-07-21	Kymab Ltd	Treatment of cancer
WO2024160721A1 (en)	2023-01-30	2024-08-08	Kymab Limited	Antibodies

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5182368A (en) *	1986-06-13	1993-01-26	Ledbetter Jeffrey A	Ligands and methods for augmenting B-cell proliferation

1994
- 1994-01-31 IL IL10850194A patent/IL108501A/en not_active IP Right Cessation
1995
- 1995-01-30 WO PCT/US1995/001137 patent/WO1995020605A1/en not_active Ceased
- 1995-01-30 JP JP52021095A patent/JP3478398B2/ja not_active Expired - Lifetime
- 1995-01-30 CN CN95192406A patent/CN1052733C/zh not_active Expired - Lifetime
- 1995-01-30 AU AU18686/95A patent/AU693526B2/en not_active Expired
- 1995-01-30 DK DK95910891T patent/DK0742795T3/da active
- 1995-01-30 DE DE69504955T patent/DE69504955T2/de not_active Expired - Lifetime
- 1995-01-30 EE EE9600107A patent/EE03285B1/xx unknown
- 1995-01-30 FI FI963004A patent/FI963004L/fi unknown
- 1995-01-30 CA CA002182289A patent/CA2182289C/en not_active Expired - Lifetime
- 1995-01-30 RU RU96116984/13A patent/RU2155190C2/ru active
- 1995-01-30 ES ES95910891T patent/ES2124533T3/es not_active Expired - Lifetime
- 1995-01-30 US US08/380,857 patent/US5897862A/en not_active Expired - Lifetime
- 1995-01-30 MD MD96-0296A patent/MD1374G2/ro unknown
- 1995-01-30 EP EP95910891A patent/EP0742795B1/en not_active Expired - Lifetime
- 1995-01-30 AT AT95910891T patent/ATE171461T1/de active
1996
- 1996-07-29 NO NO19963168A patent/NO317020B1/no not_active IP Right Cessation
- 1996-07-29 MX MX9603080A patent/MX9603080A/es not_active IP Right Cessation
- 1996-07-30 LT LT96-115A patent/LT4225B/lt not_active IP Right Cessation
- 1996-09-06 LV LVP-96-317A patent/LV11624B/en unknown

Also Published As

Publication number	Publication date
MD1374F2 (en)	1999-12-31
NO963168D0 (no)	1996-07-29
FI963004A7 (fi)	1996-09-27
LT96115A (en)	1997-05-26
DE69504955D1 (de)	1998-10-29
NO963168L (no)	1996-09-27
RU2155190C2 (ru)	2000-08-27
NO317020B1 (no)	2004-07-26
WO1995020605A1 (en)	1995-08-03
ATE171461T1 (de)	1998-10-15
CN1145077A (zh)	1997-03-12
LV11624B (en)	1997-06-20
MX9603080A (es)	1998-01-31
LV11624A (en)	1996-12-20
IL108501A (en)	1998-10-30
MD1374G2 (ro)	2000-09-30
CA2182289C (en)	2003-10-21
JPH09508390A (ja)	1997-08-26
CA2182289A1 (en)	1995-08-03
JP3478398B2 (ja)	2003-12-15
AU693526B2 (en)	1998-07-02
EP0742795A1 (en)	1996-11-20
US5897862A (en)	1999-04-27
AU1868695A (en)	1995-08-15
FI963004L (fi)	1996-09-27
DE69504955T2 (de)	1999-05-27
EE03285B1 (et)	2000-08-15
CN1052733C (zh)	2000-05-24
DK0742795T3 (da)	1999-06-14
ES2124533T3 (es)	1999-02-01
LT4225B (en)	1997-10-27
IL108501A0 (en)	1994-05-30
EP0742795B1 (en)	1998-09-23

Publication	Publication Date	Title
FI963004A0 (fi)	1996-07-29	Vasta-aineen muodostumista kiihottavia monoklonaalivasta-aineita
FI864037A7 (fi)	1987-04-08	Monoklonaaliset vasta-aineet ihmisen rintasyöpää vastaan.
DK69890D0 (da)	1990-03-16	Monoklonale antistoffer, der er reaktive med cachetin
DE69319662D1 (de)	1998-08-20	Monoklonale Antikörper gegen GP130-Protein
IL93840A0 (en)	1990-12-23	Novel monoclonal antibody to novel antigen associated with human tumors
DE69221147D1 (de)	1997-09-04	Nicht glycosylierter Anti-CD3-IgG-Antikörper
ATE71411T1 (de)	1992-01-15	Monoklonale antikoerper mit spezifitaet fuer membran-assoziierte antigene.
MY107079A (en)	1995-09-30	Method of reducing immunoglobulin e responses
DE3586216D1 (de)	1992-07-23	Brusttumorassoziiertes antigen und monoklonale antikoerper dazu.
NZ305083A (en)	1999-06-29	Use of cd40 binding proteins (a cd40 ligand or monoclonal antibody that specifically binds to cd40) for stimulating a immune response
DE3884646D1 (de)	1993-11-11	Humanes Karcinom-assoziertes Antigen und an dieses Antigen bindende Antikörper.
DE3585049D1 (de)	1992-02-13	Monoklonale antikoerper.
DK69690A (da)	1990-05-17	Humane anti-rh(d) monoklonale antistoffer
FI92716C (fi)	1994-12-27	Uudet monoklonaaliset vasta-aineet IFN-omegalle, niiden valmistusmenetelmät ja niiden käyttö IFN-omegan puhdistamiseen ja osoittamiseen
DE3580482D1 (de)	1990-12-13	Monoklonale antikoerper und immunisierung damit.
DE69129582D1 (de)	1998-07-16	Antikörper gegen menschlichen plasmin-alpha 2-plasmininhibitor-komplex, hybridoma und immunoassay
NO890116D0 (no)	1989-01-11	Monoklonale antistoffer.
DK49291D0 (da)	1991-03-19	Gramnegativ-bakterieendotoxinblokerende, monoklonale antistoffer
DE3785795D1 (de)	1993-06-17	Monoklonale anti-menschliche magenkrebs-antikoerper.
DE3687542D1 (de)	1993-03-04	Monoklonaler antikoerper gegen humanes protein c.
DK413389A (da)	1990-02-25	Monoklonale antistoffer
ATE58173T1 (de)	1990-11-15	Monoklonale antikoerper und immunisierung damit.
NO903788D0 (no)	1990-08-29	Monoklonalt antistoff mot protein c.
ATE99061T1 (de)	1994-01-15	Monoklonale human-antikoerper, spezifisch fuer rh(d).
FI875475A7 (fi)	1989-06-15	Hiiren hybridoma Lym-1 ja sillä tuotettu diagnostinen vasta-aine.