FI962937L - Kefuroksiimiaksetiilin biohyödynnettävä kidemuoto - Google Patents

Kefuroksiimiaksetiilin biohyödynnettävä kidemuoto Download PDF

Info

Publication number: FI962937L
Authority: FI; Finland
Prior art keywords: crystalline form; cefuroxime axetil; bioavailable; bioavailable crystalline; axetil
Prior art date: 1995-08-03

Application number

FI962937A

Other languages

English (en)

Swedish (sv)

Other versions

FI962937A0 (fi

FI962937A7 (fi

Inventor

Maurizio Zenoni

Mario Leone

Angelo Cattaneo

Leonardo Marsili

Original Assignee

Acs Dobfar Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-08-03

Filing date

1996-07-23

Publication date

1997-02-04

1996-07-23 Application filed by Acs Dobfar Spa filed Critical Acs Dobfar Spa

1996-07-23 Publication of FI962937A0 publication Critical patent/FI962937A0/fi

1997-02-04 Publication of FI962937L publication Critical patent/FI962937L/fi

1997-02-04 Publication of FI962937A7 publication Critical patent/FI962937A7/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/26—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group
- C07D501/34—Methylene radicals, substituted by oxygen atoms; Lactones thereof with the 2-carboxyl group with the 7-amino radical acylated by carboxylic acids containing hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/22—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

FI962937A 1995-08-03 1996-07-23 Kefuroksiimiaksetiilin biohyödynnettävä kidemuoto FI962937A7 (fi)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
IT95MI001716A IT1277426B1 (it)	1995-08-03	1995-08-03	Forma cristallina biodisponibile del cefuroxima axetil

Publications (3)

Publication Number	Publication Date
FI962937A0 FI962937A0 (fi)	1996-07-23
FI962937L true FI962937L (fi)	1997-02-04
FI962937A7 FI962937A7 (fi)	1997-02-04

Family

ID=11372130

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI962937A FI962937A7 (fi)	1995-08-03	1996-07-23	Kefuroksiimiaksetiilin biohyödynnettävä kidemuoto

Country Status (24)

Country	Link
US (1)	US5677443A (fi)
EP (1)	EP0757991B1 (fi)
JP (1)	JPH09104685A (fi)
KR (1)	KR970010776A (fi)
CN (1)	CN1055693C (fi)
AR (1)	AR003973A1 (fi)
AT (1)	ATE195126T1 (fi)
BR (1)	BR9603270A (fi)
CA (1)	CA2179359A1 (fi)
DE (1)	DE69609576T2 (fi)
DK (1)	DK0757991T3 (fi)
ES (1)	ES2150052T3 (fi)
FI (1)	FI962937A7 (fi)
GR (1)	GR3034663T3 (fi)
IL (1)	IL118822A (fi)
IT (1)	IT1277426B1 (fi)
MX (1)	MX9603110A (fi)
PT (1)	PT757991E (fi)
RU (1)	RU2155767C2 (fi)
SI (1)	SI0757991T1 (fi)
TR (1)	TR199600691A2 (fi)
TW (1)	TW413635B (fi)
UA (1)	UA46727C2 (fi)
ZA (1)	ZA965234B (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2725382B1 (fr) *	1994-10-05	1997-01-03	Commissariat Energie Atomique	Polyazacycloalcanes, complexes tri-, tetra- ou pentaazamacrocycliques, procede de fabrication de ces polyazacycloalcanes substitues ou non et greffes sur un support et utilisations des polyazacycloalcanes
NZ299077A (en) *	1996-07-26	1998-06-26	Apotex Inc	Preparation of amorphous cefuroxime axetil (a cephalosporin derivative) by dissolving crystalline cefuroxim axetil in a highly polar solvent, typically dmso and/or dmf
KR100401284B1 (ko) *	1997-06-03	2004-01-31	주식회사유한양행	1-브로모에틸 아세테이트의 제조방법
CA2209868C (en) *	1997-08-15	2001-08-14	Bernard Charles Sherman	Pharmaceutical compositions comprising cefuroxime axetil
IN186539B (fi) *	1997-09-29	2001-09-29	Ranbaxy Lab Ltd
ES2171056T3 (es) *	1998-02-20	2002-08-16	Fako Ilaclari A S	Procedimiento para la fabricacion de cefuroxima axetil cristalina soluble.
US6384213B1 (en)	1998-10-23	2002-05-07	Ranbaxy Laboratories Limited	Process for preparing a pure, pharmacopoeial grade amorphous form of cefuroxime axetil
IN190849B (fi) *	2000-07-17	2003-08-23	Ranbaxy Lab Ltd
ITMI20011763A1 (it) *	2001-08-10	2003-02-10	Antibioticos Spa	Processo di preparazione di cefuroxime axelite ad elevata purezza
ITMI20011925A1 (it) *	2001-09-14	2003-03-14	Antibioticos Spa	Metodo applicabile su scala industriale per la preparazione di cefuroxime axetile cristallino
CZ12993U1 (cs) *	2001-11-23	2003-02-10	Glaxo Group Limited	Farmaceutický prostředek
US20090175952A1 (en) *	2004-01-09	2009-07-09	Jong Soo Woo	Cefuroxime axetil granule and process for the preparation thereof
CN100448879C (zh) *	2004-07-22	2009-01-07	北京化工大学	一种无定型头孢呋辛酯的制备方法
DE102005019458A1 (de)	2005-04-25	2006-10-26	Grünenthal GmbH	Darreichungsform mit verbesserter Freisetzung von Cefuroximaxetil
US8900637B2 (en) *	2005-12-02	2014-12-02	Lupin Limited	Stable taste masked formulations of cephalosporins
DE102006019619A1 (de) *	2006-04-25	2007-10-31	Grünenthal GmbH	Kristalline Modifikation von Cefuroximaxetil
CN102417451B (zh) *	2011-12-20	2013-12-04	浙江国邦药业有限公司	一种合成（r，s）1-溴代乙基乙酸酯的制备方法
CN103717607A (zh) *	2012-09-12	2014-04-09	海南卫康制药(潜山)有限公司	头孢呋辛钠新晶型化合物及其组合物粉针
CN106554361B (zh) *	2016-09-30	2018-10-09	华北制药河北华民药业有限责任公司	一种头孢呋辛酯口服制剂的制备方法
CN115594583A (zh) *	2022-10-13	2023-01-13	浙江东盈药业有限公司（Cn）	一种1-溴乙基乙酸酯的合成方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1571683A (en) *	1976-02-16	1980-07-16	Glaxo Operations Ltd	Ester derivatives of cefuroxime
CA1094545A (en) *	1976-02-16	1981-01-27	Michael Gregson	Cephalosporin antibiotics
YU44680B (en) *	1982-07-30	1990-12-31	Glaxo Lab Ltd	Process for obtaining very pure amorphous form of cephuroxim axetile
GB8320521D0 (en) *	1983-07-29	1983-09-01	Glaxo Group Ltd	Chemical process
US5063224A (en) *	1990-07-09	1991-11-05	Eli Lilly And Company	R-cefuroxime axetil

1995
- 1995-08-03 IT IT95MI001716A patent/IT1277426B1/it active IP Right Grant
1996
- 1996-06-17 DK DK96109665T patent/DK0757991T3/da active
- 1996-06-17 DE DE69609576T patent/DE69609576T2/de not_active Expired - Fee Related
- 1996-06-17 SI SI9630229T patent/SI0757991T1/xx unknown
- 1996-06-17 ES ES96109665T patent/ES2150052T3/es not_active Expired - Lifetime
- 1996-06-17 EP EP96109665A patent/EP0757991B1/en not_active Expired - Lifetime
- 1996-06-17 PT PT96109665T patent/PT757991E/pt unknown
- 1996-06-17 AT AT96109665T patent/ATE195126T1/de not_active IP Right Cessation
- 1996-06-17 US US08/664,552 patent/US5677443A/en not_active Expired - Fee Related
- 1996-06-18 CA CA002179359A patent/CA2179359A1/en not_active Abandoned
- 1996-06-20 ZA ZA965234A patent/ZA965234B/xx unknown
- 1996-06-25 TW TW085107604A patent/TW413635B/zh not_active IP Right Cessation
- 1996-07-09 IL IL11882296A patent/IL118822A/xx not_active IP Right Cessation
- 1996-07-23 FI FI962937A patent/FI962937A7/fi unknown
- 1996-07-30 KR KR1019960031374A patent/KR970010776A/ko not_active Ceased
- 1996-07-31 MX MX9603110A patent/MX9603110A/es unknown
- 1996-08-01 AR ARP960103834A patent/AR003973A1/es unknown
- 1996-08-01 CN CN96109271A patent/CN1055693C/zh not_active Expired - Fee Related
- 1996-08-02 RU RU96115329/04A patent/RU2155767C2/ru active
- 1996-08-02 UA UA96083116A patent/UA46727C2/uk unknown
- 1996-08-02 JP JP8205098A patent/JPH09104685A/ja active Pending
- 1996-08-02 BR BR9603270A patent/BR9603270A/pt not_active Application Discontinuation
- 1996-08-28 TR TR96/00691A patent/TR199600691A2/xx unknown
2000
- 2000-10-23 GR GR20000402353T patent/GR3034663T3/el not_active IP Right Cessation

Also Published As

Publication number	Publication date
FI962937A0 (fi)	1996-07-23
GR3034663T3 (en)	2001-01-31
DE69609576T2 (de)	2001-01-04
RU2155767C2 (ru)	2000-09-10
TR199600691A3 (tr)	1998-03-21
EP0757991B1 (en)	2000-08-02
TW413635B (en)	2000-12-01
MX9603110A (es)	1997-06-28
US5677443A (en)	1997-10-14
TR199600691A2 (xx)	1998-03-21
EP0757991A1 (en)	1997-02-12
IT1277426B1 (it)	1997-11-10
CA2179359A1 (en)	1997-02-04
UA46727C2 (uk)	2002-06-17
DE69609576D1 (de)	2000-09-07
ZA965234B (en)	1997-03-06
FI962937A7 (fi)	1997-02-04
AR003973A1 (es)	1998-09-30
BR9603270A (pt)	1998-04-28
ES2150052T3 (es)	2000-11-16
JPH09104685A (ja)	1997-04-22
IL118822A (en)	1999-11-30
AU6083396A (en)	1997-02-06
DK0757991T3 (da)	2000-09-04
PT757991E (pt)	2000-11-30
KR970010776A (ko)	1997-03-27
SI0757991T1 (en)	2000-12-31
ITMI951716A0 (it)	1995-08-03
CN1055693C (zh)	2000-08-23
AU700214B2 (en)	1998-12-24
ITMI951716A1 (it)	1997-02-03
ATE195126T1 (de)	2000-08-15
CN1147516A (zh)	1997-04-16
IL118822A0 (en)	1996-10-31

Publication	Publication Date	Title
FI962937L (fi)	1997-02-04	Kefuroksiimiaksetiilin biohyödynnettävä kidemuoto
NO921217L (no)	1992-10-02	Silyletere av rapamycin
NO921976L (no)	1992-11-23	Amidestere av rapamycin
BR9711151A (pt)	1999-08-17	Forma cristalina de 4-¬5-metil-3-fenilsoxazol-4-il¾benzenossulfonamida
BR9507267A (pt)	1997-09-23	Antibióticos de cefalosporina
MX9200148A (es)	1992-07-01	Fabricacion de cuerpos de cordierita
MX9200152A (es)	1992-08-01	Fabricacion de cuerpos de cordierita
ATE292637T1 (de)	2005-04-15	Antibakterielle cephalosporine
PT874854E (pt)	2002-06-28	Antibioticos de cefalosporina
NO940912L (no)	1994-09-16	Rensing av kuldemedium
MA23970A1 (fr)	1997-04-01	Derives de cephalosporine
FI924210A7 (fi)	1993-03-21	Kiteisen peneemin valmistus
NO954322D0 (no)	1995-10-27	Krystallins monohydrat av spirostanyl-glykosid
FI973500A0 (fi)	1997-08-26	3-pyrrolidylideeni-2-oni-kefalosporiinien johdannaiset
AU700214C (en)	2000-02-10	Bioavailable crystalline form of cefuroxime axetil
FI923310A7 (fi)	1993-02-01	Pradimisiiniantibioottien tuotanto
PT761766E (pt)	2002-09-30	Compostos assimetricos de trifenilenodioxazina
BR9603734A (pt)	1998-05-26	Derivados de cefalosporina
BR9610201A (pt)	1998-08-11	Forma cristalina alternativa de tazofelona
MA23677A1 (fr)	1996-07-01	Derives de la cephalosporine
LV10277A (lv)	1994-10-20	Cefalosporina atvasinajumi
HRP930890B1 (en)	2004-04-30	The production of crystalline l-sorbose
BR9102163A (pt)	1993-01-05	Eixo-guilherme de azevedo queiroz