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FI964879A7 - Uusia, 1,1-bis(heteroazolyyli)alkaanijohdoksia ja niiden käyttö hermos toa suojelevina aineina - Google Patents

Uusia, 1,1-bis(heteroazolyyli)alkaanijohdoksia ja niiden käyttö hermos toa suojelevina aineina Download PDF

Info

Publication number
FI964879A7
FI964879A7 FI964879A FI964879A FI964879A7 FI 964879 A7 FI964879 A7 FI 964879A7 FI 964879 A FI964879 A FI 964879A FI 964879 A FI964879 A FI 964879A FI 964879 A7 FI964879 A7 FI 964879A7
Authority
FI
Finland
Prior art keywords
heteroazolyl
bis
new
neuroprotective agents
alkane derivatives
Prior art date
Application number
FI964879A
Other languages
English (en)
Swedish (sv)
Other versions
FI964879L (fi
FI964879A0 (fi
Inventor
Bernard Robin Boar
Duncan Alastair Gray
Dennis Mark O'shea
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of FI964879L publication Critical patent/FI964879L/fi
Publication of FI964879A7 publication Critical patent/FI964879A7/fi
Publication of FI964879A0 publication Critical patent/FI964879A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/24—Radicals substituted by oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Epidemiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Urology & Nephrology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI964879A 1994-06-07 1995-05-29 Uusia, 1,1-bis(heteroazolyyli)alkaanijohdoksia ja niiden käyttö hermostoa suojelevina aineina FI964879A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9401965A SE9401965D0 (sv) 1994-06-07 1994-06-07 New compounds
PCT/SE1995/000604 WO1995033747A1 (en) 1994-06-07 1995-05-29 Novel 1,1-bis(heteroazolyl)alkane derivatives and their use as neuroprotective agents

Publications (3)

Publication Number Publication Date
FI964879L FI964879L (fi) 1996-12-05
FI964879A7 true FI964879A7 (fi) 1996-12-05
FI964879A0 FI964879A0 (fi) 1996-12-05

Family

ID=20394274

Family Applications (1)

Application Number Title Priority Date Filing Date
FI964879A FI964879A0 (fi) 1994-06-07 1995-05-29 Uusia, 1,1-bis(heteroazolyyli)alkaanijohdoksia ja niiden käyttö hermostoa suojelevina aineina

Country Status (26)

Country Link
US (2) US5843971A (fi)
EP (1) EP0765325A1 (fi)
JP (1) JPH10503172A (fi)
CN (1) CN1051546C (fi)
AU (1) AU691303B2 (fi)
BR (1) BR9507923A (fi)
CA (1) CA2190128A1 (fi)
CZ (1) CZ357796A3 (fi)
DZ (1) DZ1895A1 (fi)
EE (1) EE9600197A (fi)
FI (1) FI964879A0 (fi)
HR (1) HRP950302A2 (fi)
HU (1) HUT76050A (fi)
IL (1) IL113773A (fi)
IS (1) IS4383A (fi)
MA (1) MA23574A1 (fi)
NO (1) NO307421B1 (fi)
NZ (1) NZ287973A (fi)
PL (1) PL318470A1 (fi)
RU (1) RU2155763C2 (fi)
SE (1) SE9401965D0 (fi)
SK (1) SK155696A3 (fi)
TN (1) TNSN95065A1 (fi)
WO (1) WO1995033747A1 (fi)
YU (1) YU38695A (fi)
ZA (1) ZA954145B (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9401965D0 (sv) * 1994-06-07 1994-06-07 Astra Ab New compounds
US6921538B2 (en) * 2002-05-10 2005-07-26 Allergan, Inc. Therapeutic treatments for neuropsychiatric disorders
US7649098B2 (en) * 2006-02-24 2010-01-19 Lexicon Pharmaceuticals, Inc. Imidazole-based compounds, compositions comprising them and methods of their use
TW200920355A (en) * 2007-09-06 2009-05-16 Lexicon Pharmaceuticals Inc Compositions and methods for treating immunological and inflammatory diseases and disorders

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2801794A1 (de) * 1978-01-17 1979-07-19 Basf Ag Verfahren zur herstellung von thiazolderivaten und neue thiazole
US5554620A (en) * 1993-09-14 1996-09-10 Sterling Winthrop Inc. Substituted 6,11-ethano-6,11-dihydrobenzo[b] quinolizinium salts and compositions and methods of use thereof
SE9401965D0 (sv) * 1994-06-07 1994-06-07 Astra Ab New compounds

Also Published As

Publication number Publication date
HRP950302A2 (en) 1997-08-31
US5665747A (en) 1997-09-09
EE9600197A (et) 1997-06-16
IL113773A (en) 2000-02-29
US5843971A (en) 1998-12-01
FI964879L (fi) 1996-12-05
AU691303B2 (en) 1998-05-14
FI964879A0 (fi) 1996-12-05
SE9401965D0 (sv) 1994-06-07
NO307421B1 (no) 2000-04-03
YU38695A (sh) 1998-12-23
PL318470A1 (en) 1997-06-23
SK155696A3 (en) 1997-05-07
WO1995033747A1 (en) 1995-12-14
HU9603386D0 (en) 1997-01-28
ZA954145B (en) 1995-12-07
AU2685995A (en) 1996-01-04
NO965182L (no) 1996-12-04
MA23574A1 (fr) 1995-12-31
BR9507923A (pt) 1997-09-23
IS4383A (is) 1996-11-12
JPH10503172A (ja) 1998-03-24
IL113773A0 (en) 1995-08-31
EP0765325A1 (en) 1997-04-02
CN1150426A (zh) 1997-05-21
CA2190128A1 (en) 1995-12-14
CN1051546C (zh) 2000-04-19
DZ1895A1 (fr) 2002-02-17
CZ357796A3 (en) 1997-06-11
HUT76050A (en) 1997-06-30
RU2155763C2 (ru) 2000-09-10
NZ287973A (en) 1998-04-27
NO965182D0 (no) 1996-12-04
TNSN95065A1 (fr) 1996-02-06

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