FI952302L - Pyran-2-onit ja 5,6-dihydropyranonit, jotka ovat käyttökelpoisia HIV:n ja muiden retrovirusten hoidossa - Google Patents

Pyran-2-onit ja 5,6-dihydropyranonit, jotka ovat käyttökelpoisia HIV:n ja muiden retrovirusten hoidossa Download PDF

Info

Publication number: FI952302L
Authority: FI; Finland
Prior art keywords: dihydropyranones; retroviruses; pyran; hiv; ones
Prior art date: 1992-11-13

Application number

FI952302A

Other languages

English (en)

Swedish (sv)

Other versions

FI120399B (fi

FI952302A0 (fi

Inventor

Suvit Thaisrivongs

Chih-Ping Yang

Joseph Walter Strohbach

Steven Ronald Turner

Donna Lee Romero

Louis L Skaletzki

Paul Andrian Aristoff

Ronald B Gammill

Paul D Johnson

Harvey Irving Skulnick

Richard C Piper

Ruben A Tommasi

Qingwei Zhang

Original Assignee

Upjohn Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-11-13

Filing date

1995-05-11

Publication date

1995-05-11

1995-05-11 Application filed by Upjohn Co filed Critical Upjohn Co

1995-05-11 Publication of FI952302L publication Critical patent/FI952302L/fi

1995-05-11 Publication of FI952302A0 publication Critical patent/FI952302A0/fi

2009-10-15 Application granted granted Critical

2009-10-15 Publication of FI120399B publication Critical patent/FI120399B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/26—Androgens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/32—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Animal Behavior & Ethology (AREA)
Virology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Molecular Biology (AREA)
Endocrinology (AREA)
Urology & Nephrology (AREA)
Reproductive Health (AREA)
Diabetes (AREA)
Pulmonology (AREA)
AIDS & HIV (AREA)
Tropical Medicine & Parasitology (AREA)
Dermatology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Plural Heterocyclic Compounds (AREA)
Pyrane Compounds (AREA)
Cosmetics (AREA)
Medicines Containing Plant Substances (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

FI952302A 1992-11-13 1995-05-11 Menetelmä pyran-2-onien ja 5,6-dihydropyranonien valmistamiseksi, jotka ovat käyttökelpoisia HIV:n ja muiden retrovirusten hoidossa FI120399B (fi)

Applications Claiming Priority (8)

Application Number	Priority Date	Filing Date	Title
US97534392A	1992-11-13	1992-11-13
US97534392		1992-11-13
US9087693A	1993-07-13	1993-07-13
US9087693		1993-07-13
US13064193A	1993-10-01	1993-10-01
US13064193		1993-10-01
PCT/US1993/010645 WO1994011361A1 (en)	1992-11-13	1993-11-09	Pyran-2-ones and 5,6-dihydropyran-2-ones useful for treating hiv and other retroviruses
US9310645		1993-11-09

Publications (3)

Publication Number	Publication Date
FI952302L true FI952302L (fi)	1995-05-11
FI952302A0 FI952302A0 (fi)	1995-05-11
FI120399B FI120399B (fi)	2009-10-15

Family

ID=27376682

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI952302A FI120399B (fi)	1992-11-13	1995-05-11	Menetelmä pyran-2-onien ja 5,6-dihydropyranonien valmistamiseksi, jotka ovat käyttökelpoisia HIV:n ja muiden retrovirusten hoidossa

Country Status (26)

Country	Link
EP (2)	EP1203770B1 (fi)
JP (1)	JP3583127B2 (fi)
KR (1)	KR100314975B1 (fi)
CN (1)	CN1040321C (fi)
AT (2)	ATE290531T1 (fi)
AU (1)	AU687368B2 (fi)
BR (1)	BR9307451A (fi)
CA (1)	CA2145661C (fi)
CZ (1)	CZ291853B6 (fi)
DE (2)	DE69332292T2 (fi)
DK (2)	DK0668860T3 (fi)
ES (2)	ES2182837T3 (fi)
FI (1)	FI120399B (fi)
GE (1)	GEP20094660B (fi)
HU (1)	HU228126B1 (fi)
IL (1)	IL107556A (fi)
LV (1)	LV13088B (fi)
MY (1)	MY119031A (fi)
NO (1)	NO319914B1 (fi)
NZ (1)	NZ258013A (fi)
PL (1)	PL178653B1 (fi)
PT (2)	PT1203770E (fi)
RU (1)	RU2134691C1 (fi)
SK (1)	SK285001B6 (fi)
WO (1)	WO1994011361A1 (fi)
ZA (1)	ZA938019B (fi)

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FI962019L (fi) *	1993-11-19	1996-05-20	Parke Davis & Co	Pyronijohdannaiset proteaasi-inhibiittoreina ja antiviraalisina aineina
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CN1284763C (zh) *	1997-09-11	2006-11-15	法玛西雅厄普约翰美国公司	用于制备蛋白酶抑制剂的化合物
CN1170827C (zh)	1998-03-12	2004-10-13	帝人株式会社	苯并呋喃基吡喃酮衍生物
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FI113942B (fi) *	2000-08-18	2004-07-15	Control Ox Oy	Kasviperäisten fenolisten yhdisteiden käyttö valmistettaessa klamydiainfektion hoidossa ja ennaltaehkäisyssä käyttökelpoista farmaseuttista valmistetta, terveyteen myönteisesti vaikuttavaa ravintoainekoostumusta tai koostumusta lisättäväksi tällaisiin elintarvikkeisiin
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DOP2003000641A (es)	2002-05-10	2003-11-15	Pfizer	Inhibidores de las arn polimerasa dependiente de arn del virus de las hepatitis c y composiciones y tratamiento que los usan
RU2236852C1 (ru) *	2003-06-23	2004-09-27	Закрытое акционерное общество "ДЕСКО"	Средство для ингибирования репродукции оболоченных вирусов, способ его получения, фармацевтическая композиция и способ ингибирования вирусных инфекций
JP4638441B2 (ja)	2003-10-24	2011-02-23	ロンザアーゲー	６，６，６−トリハロ−３，５−ジオキソヘキサン酸エステルの生産方法
KR101474031B1 (ko) *	2006-06-16	2014-12-17	파르마 마르 에스.에이.	항종양성 다이하이드로피란-2-온 화합물
ES2384420T3 (es)	2007-12-20	2012-07-04	Pharma Mar S.A.	Compuestos antitumorales
DE102008055914A1 (de)	2008-11-05	2010-05-06	Clariant International Limited	Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Acroleinen und ihre Verwendung
EP2346885B1 (de)	2008-11-05	2013-08-28	Clariant International Ltd.	Verfahren zur herstellung von monocarboxyfunktionaslisierten dialkylphosphinsäuren, -estern und -salzen mittels allylalkoholen/acroleinen und ihre verwendung
DE102008055916A1 (de)	2008-11-05	2010-05-06	Clariant International Limited	Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Allylalkoholen und ihre Verwendung
JP5570518B2 (ja)	2008-11-07	2014-08-13	クラリアント・ファイナンス・（ビーブイアイ）・リミテッド	アクリル酸誘導体を用いたジアルキルホスフィン酸、−エステル及び−塩の製造方法及びそれらの使用
DE102008056341A1 (de)	2008-11-07	2010-05-12	Clariant International Limited	Verfahren zur Herstellung von monoaminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Acrylnitrilen und ihre Verwendung
DE102008056342A1 (de)	2008-11-07	2010-05-12	Clariant International Limited	Verfahren zur Herstellung von Dialkylphosphinsäuren, -estern und -salzen mittels Acrylnitrilen und ihre Verwendung
DE102008056339A1 (de)	2008-11-07	2010-05-12	Clariant International Limited	Verfahren zur Herstellung von mono-aminofunktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung
JP5743219B2 (ja)	2008-11-11	2015-07-01	クラリアント・ファイナンス・（ビーブイアイ）・リミテッド	アリル化合物を用いる、モノアリル官能性ジアルキルホスフィン酸、それらの塩およびエステルの製造方法およびそれらの使用
DE102008060035A1 (de)	2008-12-02	2010-06-10	Clariant International Limited	Verfahren zur Herstellung von mono-hydroxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylester einer Carbonsäure und ihre Verwendung
DE102008060036A1 (de)	2008-12-02	2010-06-10	Clariant International Limited	Verfahren zur Herstellung von mono-carboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylester einer Carbonsäure und ihre Verwendung
DE102008060535A1 (de) *	2008-12-04	2010-06-10	Clariant International Limited	Verfahren zur Herstellung von mono-carboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Vinylether und ihre Verwendung
DE102008063668A1 (de)	2008-12-18	2010-07-01	Clariant International Limited	Verfahren zur Herstellung von Alkylphosponsäuren, -estern und -salzen mittels Oxidation von Alkylphosphonigsäuren und ihre Verwendung
DE102008063627A1 (de)	2008-12-18	2010-06-24	Clariant International Limited	Verfahren zur Herstellung von monohydroxyfunktionalisierten Dialkylphosphinsäuren,-estern und -salzen mittels Ethylenoxid und ihre Verwendung
EP2379573B1 (de)	2008-12-18	2013-12-11	Clariant Finance (BVI) Limited	Verfahren zur herstellung von ethylendialkylphosphinsäuren, -estern und -salzen mittels acetylen und ihre verwendung
DE102008063642A1 (de) *	2008-12-18	2010-06-24	Clariant International Limited	Verfahren zur Herstellung von monocarboxyfunktionalisierten Dialkylphosphinsäuren, -estern und -salzen mittels Alkylenoxiden und ihre Verwendung
DE102008064012A1 (de)	2008-12-19	2010-06-24	Clariant International Limited	Halogenfreie Addukte von Alkylphosphonigsäurederivaten und diesterbildenden Olefinen, halogenfreie Verfahren zu deren Herstellung und ihre Verwendung
DE102008064003A1 (de)	2008-12-19	2010-06-24	Clariant International Limited	Verfahren zur Herstellung von mono-funktionalisierten Dialkylphosphinsäuren, -estern und -salzen und ihre Verwendung
WO2011039735A2 (en) *	2009-10-02	2011-04-07	Consiglio Nazionale Delle Ricerche	Compounds with ddx3 inhibitory activity and uses thereof
CN102690275A (zh) *	2011-03-25	2012-09-26	中国人民解放军第二军医大学	四氢呋喃并[3,4-c]吡喃酮类化合物及其制备方法和用途
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FR1276645A (fr) *	1959-12-28	1961-11-17	Wild Heerbrugg Ag	Objectif de microscope
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JPH03503635A (ja) *	1988-03-01	1991-08-15	ジ・アップジョン・カンパニー	ヒトにおいて逆転写酵素を抑制するクマリン類
JPH05503073A (ja) *	1989-09-26	1993-05-27	オクタマー，インコーポレイテッド	ウイルス性疾患の治療に有用な６―アミノ―１，２―ベンゾピロン
WO1991006561A1 (en) *	1989-10-27	1991-05-16	The Upjohn Company	Method for treating hiv and other retroviruses and compounds useful therefor
DE4103904C2 (de) *	1991-02-08	1995-06-14	Analyticon Ges Fuer Chemische	Neue Arzneimittel aus Gamma-Pyronen, Gamma-Pyridonen sowie Gamma-Thiopyronen

1993
- 1993-10-27 ZA ZA938019A patent/ZA938019B/xx unknown
- 1993-11-09 NZ NZ258013A patent/NZ258013A/en not_active IP Right Cessation
- 1993-11-09 SK SK616-95A patent/SK285001B6/sk not_active IP Right Cessation
- 1993-11-09 AU AU55493/94A patent/AU687368B2/en not_active Expired
- 1993-11-09 DE DE69332292T patent/DE69332292T2/de not_active Expired - Lifetime
- 1993-11-09 EP EP02002073A patent/EP1203770B1/en not_active Expired - Lifetime
- 1993-11-09 ES ES94900546T patent/ES2182837T3/es not_active Expired - Lifetime
- 1993-11-09 ES ES02002073T patent/ES2237624T3/es not_active Expired - Lifetime
- 1993-11-09 BR BR9307451-4A patent/BR9307451A/pt not_active IP Right Cessation
- 1993-11-09 CA CA002145661A patent/CA2145661C/en not_active Expired - Lifetime
- 1993-11-09 DE DE69333771T patent/DE69333771T2/de not_active Expired - Lifetime
- 1993-11-09 RU RU95112465A patent/RU2134691C1/ru active
- 1993-11-09 EP EP94900546A patent/EP0668860B1/en not_active Expired - Lifetime
- 1993-11-09 PT PT02002073T patent/PT1203770E/pt unknown
- 1993-11-09 JP JP51221794A patent/JP3583127B2/ja not_active Expired - Lifetime
- 1993-11-09 WO PCT/US1993/010645 patent/WO1994011361A1/en not_active Ceased
- 1993-11-09 MY MYPI93002343A patent/MY119031A/en unknown
- 1993-11-09 PL PL93308998A patent/PL178653B1/pl unknown
- 1993-11-09 CZ CZ19951078A patent/CZ291853B6/cs not_active IP Right Cessation
- 1993-11-09 PT PT94900546T patent/PT668860E/pt unknown
- 1993-11-09 DK DK94900546T patent/DK0668860T3/da active
- 1993-11-09 DK DK02002073T patent/DK1203770T3/da active
- 1993-11-09 HU HU9501411A patent/HU228126B1/hu unknown
- 1993-11-09 AT AT02002073T patent/ATE290531T1/de active
- 1993-11-09 KR KR1019950701926A patent/KR100314975B1/ko not_active Expired - Lifetime
- 1993-11-09 AT AT94900546T patent/ATE223910T1/de active
- 1993-11-10 IL IL10755693A patent/IL107556A/en not_active IP Right Cessation
- 1993-11-12 CN CN93114470A patent/CN1040321C/zh not_active Expired - Lifetime
1995
- 1995-05-11 FI FI952302A patent/FI120399B/fi not_active IP Right Cessation
- 1995-05-12 NO NO19951899A patent/NO319914B1/no not_active IP Right Cessation
2003
- 2003-09-11 LV LVP-03-101A patent/LV13088B/en unknown
2008
- 2008-05-06 GE GEAP200810686A patent/GEP20094660B/en unknown

Also Published As

Publication number	Publication date
EP0668860B1 (en)	2002-09-11
NZ258013A (en)	1997-02-24
KR950704290A (ko)	1995-11-17
GEP20094660B (en)	2009-03-25
DE69332292T2 (de)	2003-05-28
PT1203770E (pt)	2005-05-31
PT668860E (pt)	2003-01-31
CN1090279A (zh)	1994-08-03
DK0668860T3 (da)	2003-01-20
ATE223910T1 (de)	2002-09-15
WO1994011361A1 (en)	1994-05-26
PL308998A1 (en)	1995-09-18
JP3583127B2 (ja)	2004-10-27
HU9501411D0 (en)	1995-06-28
NO951899D0 (no)	1995-05-12
SK61695A3 (en)	1995-10-11
CA2145661C (en)	2008-04-01
JPH08503216A (ja)	1996-04-09
NO319914B1 (no)	2005-10-03
ES2237624T3 (es)	2005-08-01
DE69332292D1 (de)	2002-10-17
DE69333771D1 (de)	2005-04-14
IL107556A (en)	2001-08-08
LV13088B (en)	2004-01-20
KR100314975B1 (ko)	2002-02-28
PL178653B1 (pl)	2000-05-31
HU228126B1 (en)	2012-12-28
RU2134691C1 (ru)	1999-08-20
AU5549394A (en)	1994-06-08
SK285001B6 (sk)	2006-04-06
CN1040321C (zh)	1998-10-21
EP1203770A1 (en)	2002-05-08
CZ107895A3 (en)	1995-12-13
RU95112465A (ru)	1997-03-20
EP0668860A1 (en)	1995-08-30
ATE290531T1 (de)	2005-03-15
DK1203770T3 (da)	2005-05-23
NO951899L (no)	1995-07-12
CA2145661A1 (en)	1994-05-26
BR9307451A (pt)	1999-08-31
FI120399B (fi)	2009-10-15
AU687368B2 (en)	1998-02-26
HUT71558A (en)	1995-12-28
DE69333771T2 (de)	2006-04-06
IL107556A0 (en)	1994-02-27
FI952302A0 (fi)	1995-05-11
ZA938019B (en)	1995-04-28
EP1203770B1 (en)	2005-03-09
MY119031A (en)	2005-03-31
ES2182837T3 (es)	2003-03-16
CZ291853B6 (cs)	2003-06-18

Publication	Publication Date	Title
FI952302L (fi)	1995-05-11	Pyran-2-onit ja 5,6-dihydropyranonit, jotka ovat käyttökelpoisia HIV:n ja muiden retrovirusten hoidossa
FI952179A7 (fi)	1995-05-05	Uusia 3,3-difenyylipropyyliamiineja, niiden käyttö ja valmistus
EP0831873A4 (en)	2002-07-17	COMBINATORY THERAPY FOR THE TREATMENT OF HIV AND OTHER VIRAL INFECTIONS
DE68919236D1 (de)	1994-12-15	Textilbehandlungszubereitung und deren Herstellung.
FI955315A0 (fi)	1995-11-06	HIV:n proteaasin inhibiittoreita, jotka ovat käyttökelpoisia AIDS'n hoitoon
FI891716A7 (fi)	1989-10-13	HIV-proteaasi-inhibiittoreita, jotka ovat käyttökelpoisia AIDS'in hoidossa
FI882742A7 (fi)	1988-12-11	Hoitavia aineita ja niitä sisältäviä koostumuksia.
FI953717L (fi)	1995-08-04	4-Hydroksibentsopyran-2-oneja ja 4-hydroksisykloalkyyli(b)pyran-2-oneja, joita voidaan käyttää retrovirusinfektioiden hoitamiseen
ES2130114T3 (es)	1999-07-01	5,11-dihidro-6h-dipirido(3,2-b:2',3'-e)(1,4)diazepinas y su uso en la prevencion o tratamiento de infeccion por hiv.
IT1229195B (it)	1991-07-25	Derivati xantinici ad attivita' broncodilatatrice e loro applicazioni terapeutiche.
ATE105297T1 (de)	1994-05-15	Derivate von 2'-halomethyliden, 2'-ethenyliden und 2'-ethynylcytidin, uridin und guanosin.
ATE100098T1 (de)	1994-01-15	Nukleoside, ihre herstellung und pharmazeutische zusammenstellungen.
DE68913739D1 (de)	1994-04-14	Kosmetische und hautbehandlungs-zusammensetzungen.
MX9203459A (es)	1992-08-01	Nuevos derivados de 2'-halometilideno, 2'-etenilideno y 2'-etinilcitidina, uridina y guanosina.
FI932847A0 (fi)	1993-06-18	HIV-proteasinhibitorer som aer anvaendbara foer behandling av aids
DE58902899D1 (de)	1993-01-14	2',3'-dideoxypurinnucleosid/purinnucleosid-phosphorylase-inhibitor kombinationstherapie und zusammensetzungen dafuer.
DE69002520D1 (de)	1993-09-09	Azeotropaehnliche zusammensetzungen von 1,1-dichlor-2,2,2-trifluoraethan und 1,1-dochlor-1-fluoraethan.
FI923458A7 (fi)	1992-07-31	4,5-sykloalkano-3-bentsatsepin-7-olijohdannaiset ja niiden käyttö
EP0437026A3 (en)	1991-10-02	Use of tandospirone in the treatment of depression
IL110967A0 (en)	1994-11-28	Substituted tetronic acids useful for treating hiv and other retroviruses
DE69012298D1 (de)	1994-10-13	Heizen von Lagern und dergleichen.
FI945562A7 (fi)	1995-05-27	1,3,4-oksadiatsol-2(3H)-onijohdannaiset, niiden valmistus ja terapeuttinen käyttö
FI895286A7 (fi)	1990-05-09	Fenyylioksipropanoliamineja, niiden valmistus ja terapeuttinen käyttö
FI893366A7 (fi)	1990-01-13	4-piperidyylimetyyli-2,3-dihydro-1H-isoindoli- ja 2,3,4,5-tetrahydro-1H-bentsatsepiinijohdannaiset, niiden valmistus ja terapeuttinen käyttö
FI933468A7 (fi)	1994-02-06	Tetrahydronaftaleenijohdannaiset, niiden valmistus ja niiden terapeuttinen käyttö

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Date	Code	Title	Description
1996-07-16	HC	Name/ company changed in application	Owner name: PHARMACIA & UPJOHN COMPANY
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