FI954105A7 - New 4-aminopyridines, their preparation method and drugs containing these compounds - Google Patents
New 4-aminopyridines, their preparation method and drugs containing these compounds Download PDFInfo
- Publication number
- FI954105A7 FI954105A7 FI954105A FI954105A FI954105A7 FI 954105 A7 FI954105 A7 FI 954105A7 FI 954105 A FI954105 A FI 954105A FI 954105 A FI954105 A FI 954105A FI 954105 A7 FI954105 A7 FI 954105A7
- Authority
- FI
- Finland
- Prior art keywords
- aminopyridines
- compounds
- preparation
- new
- drugs containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE4306506A DE4306506A1 (en) | 1993-03-03 | 1993-03-03 | Novel 4-alkylaminopyridines - processes for their preparation and medicaments containing these compounds |
| DE19934312966 DE4312966A1 (en) | 1993-04-21 | 1993-04-21 | Novel 4-aminopyridines - process for their preparation and medicaments containing these compounds |
| PCT/EP1994/000608 WO1994020467A1 (en) | 1993-03-03 | 1994-03-02 | New 4-aminopyridines, process for preparing the same and medicaments containing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI954105A7 true FI954105A7 (en) | 1995-09-01 |
| FI954105A0 FI954105A0 (en) | 1995-09-01 |
Family
ID=25923593
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI954105A FI954105A0 (en) | 1993-03-03 | 1994-03-02 | Novel 4-aminopyridines, their method of preparation and drugs containing these compounds |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP0687253B1 (en) |
| JP (1) | JPH08507503A (en) |
| KR (1) | KR100252551B1 (en) |
| CN (1) | CN1046710C (en) |
| AT (1) | ATE174590T1 (en) |
| AU (1) | AU682026B2 (en) |
| CA (1) | CA2156729A1 (en) |
| CZ (1) | CZ225495A3 (en) |
| DE (1) | DE59407494D1 (en) |
| DK (1) | DK0687253T3 (en) |
| ES (1) | ES2127919T3 (en) |
| FI (1) | FI954105A0 (en) |
| GR (1) | GR3029691T3 (en) |
| HU (1) | HUT72898A (en) |
| IL (1) | IL108786A (en) |
| NO (1) | NO953447D0 (en) |
| NZ (1) | NZ262725A (en) |
| PL (1) | PL176455B1 (en) |
| RU (1) | RU2126388C1 (en) |
| SK (1) | SK108295A3 (en) |
| TW (1) | TW257757B (en) |
| WO (1) | WO1994020467A1 (en) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4430755A1 (en) * | 1994-08-30 | 1996-03-07 | Boehringer Mannheim Gmbh | New phosphine oxides, processes for their preparation and medicaments containing these compounds |
| IL115420A0 (en) | 1994-09-26 | 1995-12-31 | Zeneca Ltd | Aminoheterocyclic derivatives |
| US5792769A (en) * | 1995-09-29 | 1998-08-11 | 3-Dimensional Pharmaceuticals, Inc. | Guanidino protease inhibitors |
| GB9525620D0 (en) * | 1995-12-15 | 1996-02-14 | Glaxo Group Ltd | Chemical compounds |
| JP2000503010A (en) | 1995-12-29 | 2000-03-14 | スリー―ダイメンショナル・ファーマスーティカルス・インコーポレーテッド | Amidino protease inhibitor |
| US6313127B1 (en) | 1996-02-02 | 2001-11-06 | Zeneca Limited | Heterocyclic compounds useful as pharmaceutical agents |
| GB9602166D0 (en) | 1996-02-02 | 1996-04-03 | Zeneca Ltd | Aminoheterocyclic derivatives |
| SE9602646D0 (en) | 1996-07-04 | 1996-07-04 | Astra Ab | Pharmaceutically useful compounds |
| IL128428A0 (en) * | 1996-08-14 | 2000-01-31 | Zeneca Ltd | Substituted pyrimidine derivatives and their pharmaceutical use |
| CA2264037A1 (en) * | 1996-09-13 | 1998-03-19 | Merck & Co., Inc. | Thrombin inhibitors |
| GB9821483D0 (en) | 1998-10-03 | 1998-11-25 | Glaxo Group Ltd | Chemical compounds |
| UA56197C2 (en) | 1996-11-08 | 2003-05-15 | Зенека Лімітед | Heterocyclic derivatives |
| TW499412B (en) | 1996-11-26 | 2002-08-21 | Dimensional Pharm Inc | Aminoguanidines and alkoxyguanidines as protease inhibitors |
| US6127191A (en) * | 1996-12-03 | 2000-10-03 | 3-Dimensional Pharmaceuticals, Inc. | Aminobenzenedicarboxylic acid-based combinatorial libraries |
| EP0966462B1 (en) | 1997-02-13 | 2003-06-11 | AstraZeneca AB | Heterocyclic compounds useful as oxido-squalene cyclase inhibitors |
| JP2001511798A (en) | 1997-02-13 | 2001-08-14 | ゼネカ・リミテッド | Heterocyclic compounds useful as oxide-squalene cyclase inhibitors |
| GB9715895D0 (en) | 1997-07-29 | 1997-10-01 | Zeneca Ltd | Heterocyclic compounds |
| JP4327915B2 (en) * | 1998-03-30 | 2009-09-09 | 株式会社デ・ウエスタン・セラピテクス研究所 | Sulfonamide derivatives |
| DE69923467D1 (en) | 1998-10-06 | 2005-03-03 | Dainippon Pharmaceutical Co | 2,3-DISUBSTITUTED PYRIDINE DERIVATIVES, DERIVED PRODUCTION METHODS, ACTIVE INGREDIENT PREPARATIONS AND INTERMEDIATE PRODUCTS FOR THE PREPARATION THEREOF |
| GB9902989D0 (en) | 1999-02-11 | 1999-03-31 | Zeneca Ltd | Heterocyclic derivatives |
| AR023510A1 (en) | 1999-04-21 | 2002-09-04 | Astrazeneca Ab | A TEAM OF PARTS, PHARMACEUTICAL FORMULATION AND USE OF A THROMBIN INHIBITOR. |
| MXPA03000963A (en) | 2000-08-04 | 2004-04-05 | Dimensional Pharm Inc | Cyclic oxyguanidine protease inhibitors. |
| EP1331221B1 (en) * | 2000-10-04 | 2009-01-14 | Kissei Pharmaceutical Co., Ltd. | 5-amidino-2-hydroxybenzenesulfonamide derivatives, pharmaceutical compositions containing the same and intermediates for their preparation |
| US6849635B2 (en) * | 2001-05-07 | 2005-02-01 | Smithkline Beecham Corporation | Sulfonamides |
| WO2002089740A2 (en) * | 2001-05-07 | 2002-11-14 | Smithkline Beecham Corporation | Sulfonamides |
| CN1678314A (en) | 2002-08-27 | 2005-10-05 | 默克专利有限公司 | Glycine amide derivatives as raf-kinase inhibitors |
| BR0314126A (en) | 2002-09-20 | 2005-06-28 | Pfizer Prod Inc | Acyclic Amide and Sulphonamide Ligands for Estrogen Receptor |
| JP4745244B2 (en) | 2003-11-05 | 2011-08-10 | エフ．ホフマン−ラ ロシュ アーゲー | Phenyl derivatives as PPAR agonists |
| EP2125735B1 (en) * | 2007-02-28 | 2012-06-27 | Advinus Therapeutics Private Limited | 2,2,2-tri-substituted acetamide derivatives as glucokinase activators, their process and pharmaceutical application |
| RU2353619C2 (en) * | 2007-06-28 | 2009-04-27 | Общество С Ограниченной Ответственностью "Бионика" | Novel compounds possessing anticoagulant function, based on them pharmaceutical compositions for treatment of thrombotic conditions and plasma-substituting solution for correction of hypercoagulation disorders in hemodilution |
| RU2354647C2 (en) * | 2007-06-28 | 2009-05-10 | Общество С Ограниченной Ответственностью "Бионика" | New compounds with thrombin inhibiting function, and based pharmaceutical compositions |
| GB0815781D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB0815782D0 (en) | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| GB0815784D0 (en) * | 2008-08-29 | 2008-10-08 | Xention Ltd | Novel potassium channel blockers |
| US8265575B2 (en) * | 2009-06-16 | 2012-09-11 | Mediatek Inc. | Methods for handling a transmitting process and communication apparatuses utilizing the same |
| US8207639B2 (en) | 2009-10-23 | 2012-06-26 | Sunonwealth Electric Machine Industry Co., Ltd. | Motor and heating dissipating fan including motor having an annular balancing member |
| RU2685261C1 (en) * | 2018-04-05 | 2019-04-17 | Общество с ограниченной ответственностью "ФК ЛАБОРАТОРИЗ" | 4-amino-1-{2-[3-methyl-5-(benzenesulfonyloxy]phenoxy]ethyl}-pyridium chloride substance, having the biologically active agent properties, influencing the mammals blood coagulability naturally running processes, anticoagulant on its basis and its obtaining method by chemical synthesis |
| CN109172573B (en) * | 2018-09-12 | 2021-01-26 | 黑龙江中桂制药有限公司 | Oral antithrombotic drug and application thereof |
| CN110669337B (en) * | 2019-07-08 | 2020-09-25 | 中国科学院长春应用化学研究所 | Aromatic diamine monomer and preparation method thereof |
| AU2024275661A1 (en) * | 2023-05-23 | 2026-01-15 | Institute For Cancer Research D/B/A The Research Institute Of Fox Chase Cancer Center | Compounds that re-activate mutant p53 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU1097620A1 (en) * | 1983-02-16 | 1984-06-15 | Новокузнецкий научно-исследовательский химико-фармацевтический институт | Process for preparing diethyl-n-(6-methyl-pyridyl)-2-aminomethyl malonate |
| SU1318599A1 (en) * | 1985-06-26 | 1987-06-23 | МГУ им.М.В.Ломоносова | Method for producing 1-alkyl-2-chlorine-2-alkoxyethenylalkyl (aryl)chlorphosphines |
| DE3529529A1 (en) * | 1985-08-17 | 1987-02-19 | Boehringer Mannheim Gmbh | METHOD FOR PRODUCING A STABLE MODIFICATION OF TORASEMIDE |
| GB8819307D0 (en) * | 1988-08-13 | 1988-09-14 | Pfizer Ltd | Antiarrhythmic agents |
| JPH0256465A (en) * | 1988-08-22 | 1990-02-26 | Hamari Yakuhin Kogyo Kk | Acetamide compound |
| US4885927A (en) * | 1988-09-12 | 1989-12-12 | General Motors Corporation | Method and apparatus for press forming intricate metallic shapes such as spool valve elements |
| US5539104A (en) * | 1991-10-31 | 1996-07-23 | Smithkline Beecham Corp. | 1,4 Diazocines as fibrinogen antagonists |
| AU2915892A (en) * | 1991-11-14 | 1993-06-15 | Glaxo Group Limited | Piperidine acetic acid derivatives as inhibitors of fibrinogen-dependent blood platelet aggregation |
| DE4212304A1 (en) * | 1992-04-13 | 1993-10-14 | Cassella Ag | Aspartic acid derivatives, their preparation and use |
-
1994
- 1994-02-22 TW TW083101504A patent/TW257757B/zh active
- 1994-02-28 IL IL10878694A patent/IL108786A/en not_active IP Right Cessation
- 1994-03-02 HU HU9502568A patent/HUT72898A/en unknown
- 1994-03-02 FI FI954105A patent/FI954105A0/en unknown
- 1994-03-02 KR KR1019950703694A patent/KR100252551B1/en not_active Expired - Fee Related
- 1994-03-02 SK SK1082-95A patent/SK108295A3/en unknown
- 1994-03-02 ES ES94909909T patent/ES2127919T3/en not_active Expired - Lifetime
- 1994-03-02 NZ NZ262725A patent/NZ262725A/en unknown
- 1994-03-02 AT AT94909909T patent/ATE174590T1/en not_active IP Right Cessation
- 1994-03-02 JP JP6519556A patent/JPH08507503A/en active Pending
- 1994-03-02 EP EP94909909A patent/EP0687253B1/en not_active Expired - Lifetime
- 1994-03-02 CN CN94191554A patent/CN1046710C/en not_active Expired - Fee Related
- 1994-03-02 AU AU62574/94A patent/AU682026B2/en not_active Ceased
- 1994-03-02 PL PL94310520A patent/PL176455B1/en unknown
- 1994-03-02 RU RU95122612A patent/RU2126388C1/en active
- 1994-03-02 WO PCT/EP1994/000608 patent/WO1994020467A1/en not_active Ceased
- 1994-03-02 CA CA002156729A patent/CA2156729A1/en not_active Abandoned
- 1994-03-02 DE DE59407494T patent/DE59407494D1/en not_active Expired - Fee Related
- 1994-03-02 DK DK94909909T patent/DK0687253T3/en active
- 1994-03-02 CZ CZ952254A patent/CZ225495A3/en unknown
-
1995
- 1995-09-01 NO NO953447A patent/NO953447D0/en unknown
-
1999
- 1999-03-16 GR GR990400775T patent/GR3029691T3/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| TW257757B (en) | 1995-09-21 |
| KR960701019A (en) | 1996-02-24 |
| ATE174590T1 (en) | 1999-01-15 |
| CA2156729A1 (en) | 1994-09-15 |
| GR3029691T3 (en) | 1999-06-30 |
| WO1994020467A1 (en) | 1994-09-15 |
| HUT72898A (en) | 1996-06-28 |
| NZ262725A (en) | 1997-05-26 |
| RU2126388C1 (en) | 1999-02-20 |
| CN1119858A (en) | 1996-04-03 |
| DK0687253T3 (en) | 1999-08-23 |
| CN1046710C (en) | 1999-11-24 |
| PL310520A1 (en) | 1995-12-27 |
| SK108295A3 (en) | 1996-06-05 |
| IL108786A (en) | 1999-04-11 |
| EP0687253A1 (en) | 1995-12-20 |
| HU9502568D0 (en) | 1995-11-28 |
| NO953447L (en) | 1995-09-01 |
| AU6257494A (en) | 1994-09-26 |
| ES2127919T3 (en) | 1999-05-01 |
| JPH08507503A (en) | 1996-08-13 |
| EP0687253B1 (en) | 1998-12-16 |
| FI954105A0 (en) | 1995-09-01 |
| NO953447D0 (en) | 1995-09-01 |
| CZ225495A3 (en) | 1996-01-17 |
| AU682026B2 (en) | 1997-09-18 |
| DE59407494D1 (en) | 1999-01-28 |
| PL176455B1 (en) | 1999-05-31 |
| IL108786A0 (en) | 1994-06-24 |
| KR100252551B1 (en) | 2000-05-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| HC | Name/ company changed in application |
Owner name: ROCHE DIAGNOSTICS GMBH |