FI943376L - Fenyyli-imidatsolidinonijohdannaiset, menetelmä niiden valmistamiseksi ja niiden käyttö 5HT3-reseptoriantagonisteina - Google Patents
Fenyyli-imidatsolidinonijohdannaiset, menetelmä niiden valmistamiseksi ja niiden käyttö 5HT3-reseptoriantagonisteina Download PDFInfo
- Publication number
- FI943376L FI943376L FI943376A FI943376A FI943376L FI 943376 L FI943376 L FI 943376L FI 943376 A FI943376 A FI 943376A FI 943376 A FI943376 A FI 943376A FI 943376 L FI943376 L FI 943376L
- Authority
- FI
- Finland
- Prior art keywords
- phenylimidazolidinone
- derivatives
- preparation
- receptor antagonists
- antagonists
- Prior art date
Links
- QKKGTRSHKSWYAK-UHFFFAOYSA-N 1-phenylimidazolidin-2-one Chemical class O=C1NCCN1C1=CC=CC=C1 QKKGTRSHKSWYAK-UHFFFAOYSA-N 0.000 title 1
- 102000035037 5-HT3 receptors Human genes 0.000 title 1
- 108091005477 5-HT3 receptors Proteins 0.000 title 1
- 239000002464 receptor antagonist Substances 0.000 title 1
- 229940044551 receptor antagonist Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Anesthesiology (AREA)
- Addiction (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929224144A GB9224144D0 (en) | 1992-11-18 | 1992-11-18 | Phenyl-imidazolidinone derivatives and process for their preparation |
| PCT/EP1993/002924 WO1994011347A1 (en) | 1992-11-18 | 1993-10-22 | Phenyl-imidazolidinone derivatives, process for their preparation and their use as 5ht3 receptor antagonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI943376A0 FI943376A0 (fi) | 1994-07-15 |
| FI943376L true FI943376L (fi) | 1994-07-15 |
| FI943376A7 FI943376A7 (fi) | 1994-07-15 |
Family
ID=10725269
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI943376A FI943376A7 (fi) | 1992-11-18 | 1993-10-22 | Fenyyli-imidatsolidinonijohdannaiset, menetelmä niiden valmistamiseksi ja niiden käyttö 5HT3-reseptoriantagonisteina |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US5424328A (fi) |
| EP (1) | EP0623114B1 (fi) |
| JP (1) | JP3794696B2 (fi) |
| CN (1) | CN1093702A (fi) |
| AT (1) | ATE179701T1 (fi) |
| AU (1) | AU666793B2 (fi) |
| CA (1) | CA2127536C (fi) |
| DE (1) | DE69324794T2 (fi) |
| ES (1) | ES2133415T3 (fi) |
| FI (1) | FI943376A7 (fi) |
| GB (1) | GB9224144D0 (fi) |
| HU (1) | HUT70395A (fi) |
| IL (1) | IL107371A (fi) |
| NZ (1) | NZ257117A (fi) |
| PL (1) | PL174416B1 (fi) |
| RU (1) | RU2126403C1 (fi) |
| TW (1) | TW233297B (fi) |
| WO (1) | WO1994011347A1 (fi) |
| ZA (1) | ZA938206B (fi) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5780492A (en) * | 1996-04-03 | 1998-07-14 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| US6455424B1 (en) * | 2000-08-07 | 2002-09-24 | Micron Technology, Inc. | Selective cap layers over recessed polysilicon plugs |
| EP2858501A4 (en) * | 2012-05-22 | 2015-12-09 | Merck Sharp & Dohme | TRKA KINASE INHIBITORS, COMPOSITIONS AND METHOD THEREFOR |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3459757A (en) * | 1965-10-22 | 1969-08-05 | American Cyanamid Co | Imidazolidines |
| US3491098A (en) * | 1967-05-29 | 1970-01-20 | Sterling Drug Inc | 1-((imidazolyl)-lower-alkyl)-4-substituted-piperazines |
| US3702327A (en) * | 1970-12-28 | 1972-11-07 | Aldrich Chem Co Inc | N-beta-1-(3-phenylimidazolidin-2-one)ethyl 4,4-ethylene dioxypiperidines |
| JPS6133172A (ja) * | 1984-07-24 | 1986-02-17 | Kotobuki Seiyaku Kk | １，３−置換−２−イミダゾリジノン誘導体，胃腸運動亢進剤及びその製造方法 |
| US4600430A (en) * | 1985-02-22 | 1986-07-15 | Eli Lilly And Company | Pyridinylimidazolidinone compounds |
| JPS62135464A (ja) * | 1985-12-10 | 1987-06-18 | Nippon Kayaku Co Ltd | フエニルピペラジン誘導体 |
| FI90869C (fi) * | 1986-11-14 | 1994-04-11 | Tanabe Seiyaku Co | Menetelmä lääkeaineena käyttökelpoisten imidatsolidinonijohdannaisten valmistamiseksi |
| GB8812002D0 (en) * | 1988-05-20 | 1988-06-22 | Glaxo Group Ltd | Chemical compounds |
| GB8720693D0 (en) * | 1987-09-03 | 1987-10-07 | Glaxo Group Ltd | Chemical compounds |
| AU611976B2 (en) * | 1987-12-24 | 1991-06-27 | John Wyeth & Brother Limited | Aroyl urea and carbamic acid derivatives of azabicyclo compounds |
| IT1230703B (it) * | 1989-01-26 | 1991-10-29 | Luso Farmaco Inst | Derivati imidazolonici ad attivita' antiipertensiva, loro metodi di preparazione e composizioni farmaceutiche che li contengono. |
| GB2248058B (en) * | 1990-09-21 | 1994-09-14 | Orion Yhtymae Oy | Aromatase inhibiting 4(5)-imidazoles |
| GB9106571D0 (en) * | 1991-03-27 | 1991-05-15 | Erba Carlo Spa | Derivatives of substituted imidazol-2-one and process for their preparation |
| GB9020889D0 (en) * | 1990-09-25 | 1990-11-07 | May & Baker Ltd | New compositions of matter |
| IT1255802B (it) * | 1992-08-07 | 1995-11-16 | Luso Farmaco Inst | Derivati imidazolici ad attivita' a ii antagonista |
-
1992
- 1992-11-18 GB GB929224144A patent/GB9224144D0/en active Pending
-
1993
- 1993-10-22 WO PCT/EP1993/002924 patent/WO1994011347A1/en not_active Ceased
- 1993-10-22 AT AT93923529T patent/ATE179701T1/de not_active IP Right Cessation
- 1993-10-22 HU HU9401948A patent/HUT70395A/hu unknown
- 1993-10-22 DE DE69324794T patent/DE69324794T2/de not_active Expired - Fee Related
- 1993-10-22 AU AU53364/94A patent/AU666793B2/en not_active Ceased
- 1993-10-22 ES ES93923529T patent/ES2133415T3/es not_active Expired - Lifetime
- 1993-10-22 CA CA002127536A patent/CA2127536C/en not_active Expired - Fee Related
- 1993-10-22 RU RU94036775A patent/RU2126403C1/ru active
- 1993-10-22 EP EP93923529A patent/EP0623114B1/en not_active Expired - Lifetime
- 1993-10-22 NZ NZ257117A patent/NZ257117A/en unknown
- 1993-10-22 JP JP51163994A patent/JP3794696B2/ja not_active Expired - Fee Related
- 1993-10-22 IL IL107371A patent/IL107371A/en not_active IP Right Cessation
- 1993-10-22 PL PL93304676A patent/PL174416B1/pl unknown
- 1993-10-22 FI FI943376A patent/FI943376A7/fi not_active Application Discontinuation
- 1993-10-28 TW TW082108991A patent/TW233297B/zh active
- 1993-11-02 US US08/144,514 patent/US5424328A/en not_active Expired - Lifetime
- 1993-11-03 ZA ZA938206A patent/ZA938206B/xx unknown
- 1993-11-17 CN CN93114768A patent/CN1093702A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| TW233297B (fi) | 1994-11-01 |
| IL107371A0 (en) | 1994-01-25 |
| AU5336494A (en) | 1994-06-08 |
| WO1994011347A1 (en) | 1994-05-26 |
| ES2133415T3 (es) | 1999-09-16 |
| HUT70395A (en) | 1995-10-30 |
| AU666793B2 (en) | 1996-02-22 |
| DE69324794T2 (de) | 1999-12-02 |
| FI943376A0 (fi) | 1994-07-15 |
| JP3794696B2 (ja) | 2006-07-05 |
| PL174416B1 (pl) | 1998-07-31 |
| ZA938206B (en) | 1994-06-10 |
| RU94036775A (ru) | 1996-05-27 |
| NZ257117A (en) | 1995-08-28 |
| RU2126403C1 (ru) | 1999-02-20 |
| EP0623114B1 (en) | 1999-05-06 |
| US5424328A (en) | 1995-06-13 |
| JPH07503256A (ja) | 1995-04-06 |
| HU9401948D0 (en) | 1994-09-28 |
| PL304676A1 (en) | 1995-01-09 |
| GB9224144D0 (en) | 1993-01-06 |
| DE69324794D1 (de) | 1999-06-10 |
| FI943376A7 (fi) | 1994-07-15 |
| EP0623114A1 (en) | 1994-11-09 |
| CA2127536C (en) | 2005-09-06 |
| CA2127536A1 (en) | 1994-05-26 |
| ATE179701T1 (de) | 1999-05-15 |
| CN1093702A (zh) | 1994-10-19 |
| IL107371A (en) | 1998-02-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| GB | Transfer or assigment of application |
Owner name: PHARMACIA & UPJOHN S.P.A. |
|
| FD | Application lapsed |