FI940075L - Menetelmä bakkatiini-III- ja 10-desasetyylibakkatiini-III-johdannaisten valmistamiseksi - Google Patents

Menetelmä bakkatiini-III- ja 10-desasetyylibakkatiini-III-johdannaisten valmistamiseksi Download PDF

Info

Publication number: FI940075L
Authority: FI; Finland
Prior art keywords: iii; preparation; desacetylbaccatin; derivatives; baccatin
Prior art date: 1991-07-10

Application number

FI940075A

Other languages

English (en)

Swedish (sv)

Other versions

FI940075A0 (fi

FI109792B (fi

Inventor

Augustin Hittinger

Original Assignee

Rhone Poulenc Rorer Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-07-10

Filing date

1994-01-07

Publication date

1994-01-07

1994-01-07 Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa

1994-01-07 Publication of FI940075A0 publication Critical patent/FI940075A0/fi

1994-01-07 Publication of FI940075L publication Critical patent/FI940075L/fi

2002-10-15 Application granted granted Critical

2002-10-15 Publication of FI109792B publication Critical patent/FI109792B/fi

Links

OVMSOCFBDVBLFW-VHLOTGQHSA-N 5beta,20-epoxy-1,7beta,13alpha-trihydroxy-9-oxotax-11-ene-2alpha,4alpha,10beta-triyl 4,10-diacetate 2-benzoate Chemical compound O([C@@H]1[C@@]2(C[C@H](O)C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)O)C(=O)C1=CC=CC=C1 OVMSOCFBDVBLFW-VHLOTGQHSA-N 0.000 title 2
YWLXLRUDGLRYDR-SKXCCXORSA-N 10-dab iii Chemical class O([C@H]1C2[C@@](C([C@H](O)C3=C(C)[C@@H](O)C[C@]1(O)C3(C)C)=O)(C)[C@@H](O)C[C@H]1OC[C@]12OC(=O)C)C(=O)C1=CC=CC=C1 YWLXLRUDGLRYDR-SKXCCXORSA-N 0.000 title 1
229930014667 baccatin III Natural products 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Epoxy Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Peptides Or Proteins (AREA)
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Cephalosporin Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Saccharide Compounds (AREA)
Steroid Compounds (AREA)

FI940075A 1991-07-10 1994-01-07 Menetelmä bakkatiini-III- ja 10-desasetyylibakkatiini-III-johdannaisten valmistamiseksi FI109792B (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
FR9108673		1991-07-10
FR9108673A FR2678930B1 (fr)	1991-07-10	1991-07-10	Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.
PCT/FR1992/000649 WO1993001179A1 (fr)	1991-07-10	1992-07-08	Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR9200649		1992-07-08

Publications (3)

Publication Number	Publication Date
FI940075A0 FI940075A0 (fi)	1994-01-07
FI940075L true FI940075L (fi)	1994-01-07
FI109792B FI109792B (fi)	2002-10-15

Family

ID=9414931

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI940075A FI109792B (fi)	1991-07-10	1994-01-07	Menetelmä bakkatiini-III- ja 10-desasetyylibakkatiini-III-johdannaisten valmistamiseksi

Country Status (25)

Country	Link
US (1)	US5578739A (fi)
EP (2)	EP0522958A1 (fi)
JP (1)	JP3085710B2 (fi)
KR (1)	KR100206458B1 (fi)
AT (1)	ATE132145T1 (fi)
AU (1)	AU662346B2 (fi)
CA (1)	CA2111319C (fi)
CZ (1)	CZ281288B6 (fi)
DE (1)	DE69207194T2 (fi)
DK (1)	DK0593641T3 (fi)
ES (1)	ES2081120T3 (fi)
FI (1)	FI109792B (fi)
FR (1)	FR2678930B1 (fi)
GR (1)	GR3018543T3 (fi)
HU (1)	HU217115B (fi)
IE (1)	IE73637B1 (fi)
MX (1)	MX9204029A (fi)
NO (2)	NO302521B1 (fi)
NZ (1)	NZ243491A (fi)
PL (1)	PL169780B1 (fi)
RU (1)	RU2088578C1 (fi)
SK (1)	SK281560B6 (fi)
WO (1)	WO1993001179A1 (fi)
YU (1)	YU49175B (fi)
ZA (1)	ZA925098B (fi)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6794523B2 (en)	1991-09-23	2004-09-21	Florida State University	Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US5272171A (en) *	1992-02-13	1993-12-21	Bristol-Myers Squibb Company	Phosphonooxy and carbonate derivatives of taxol
US5294637A (en) *	1992-07-01	1994-03-15	Bristol-Myers Squibb Company	Fluoro taxols
US5380751A (en) *	1992-12-04	1995-01-10	Bristol-Myers Squibb Company	6,7-modified paclitaxels
CA2111527C (en) *	1992-12-24	2000-07-18	Jerzy Golik	Phosphonooxymethyl ethers of taxane derivatives
US5646176A (en) *	1992-12-24	1997-07-08	Bristol-Myers Squibb Company	Phosphonooxymethyl ethers of taxane derivatives
FR2703049B1 (fr) *	1993-03-22	1995-04-21	Rhone Poulenc Rorer Sa	Procédé de purification des taxoïdes.
CA2129288C (en) *	1993-08-17	2000-05-16	Jerzy Golik	Phosphonooxymethyl esters of taxane derivatives
FR2718135B1 (fr) *	1994-04-05	1996-04-26	Rhone Poulenc Rorer Sa	Procédé de préparation d'hydroxy-7 taxanes.
US5580899A (en) *	1995-01-09	1996-12-03	The Liposome Company, Inc.	Hydrophobic taxane derivatives
US6107332A (en)	1995-09-12	2000-08-22	The Liposome Company, Inc.	Hydrolysis-promoting hydrophobic taxane derivatives
US6051600A (en) *	1995-09-12	2000-04-18	Mayhew; Eric	Liposomal hydrolysis-promoting hydrophobic taxane derivatives
FR2740451B1 (fr) *	1995-10-27	1998-01-16	Seripharm	Nouveaux intermediaires pour l'hemisynthese de taxanes, leurs procedes de preparation et leur utilisation dans la synthese generale des taxanes
FR2742751B1 (fr) *	1995-12-22	1998-01-30	Rhone Poulenc Rorer Sa	Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
US7288665B1 (en) *	1997-08-18	2007-10-30	Florida State University	Process for selective derivatization of taxanes
EP1019347B1 (en) *	1997-08-21	2003-03-19	Florida State University	Method for the synthesis of taxanes
US5917062A (en) *	1997-11-21	1999-06-29	Indena S.P.A	Intermediates and methods useful in the semisynthesis of paclitaxel and analogs
DK1068192T3 (da) *	1998-01-14	2002-10-14	Bristol Myers Squibb Co	Hidtil ukendte krystallinske komplekser af baccatin III med imidazol, 2-methylimidazol eller isopropanol
IL139316A0 (en) *	1998-05-01	2001-11-25	Napro Biotherapeutics Inc	Methods and intermediate compounds for preparing paclitaxel
EP1229934B1 (en)	1999-10-01	2014-03-05	Immunogen, Inc.	Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
IT1319168B1 (it) *	2000-03-17	2003-09-26	Indena Spa	Derivati di condensazione ad attivita' antitumorale, loro metodo dipreparazione e formulazioni che li contengono.
AU2007227224A1 (en)	2006-03-23	2007-09-27	Novartis Ag	Anti-tumor cell antigen antibody therapeutics
DE102008013929B3 (de) *	2008-03-12	2009-04-09	Wieland-Werke Ag	Verdampferrohr mit optimierten Hinterschneidungen am Nutengrund
CN101531645B (zh) *	2009-04-29	2012-08-22	深圳万乐药业有限公司	一种多西他赛的合成方法
JP6427097B2 (ja)	2012-06-15	2018-11-21	ザブリガムアンドウィメンズホスピタルインコーポレイテッドＴｈｅＢｒｉｇｈａｍａｎｄＷｏｍｅｎ’ｓＨｏｓｐｉｔａｌ，Ｉｎｃ．	癌を処置するための組成物および該組成物を製造するための方法
US10426753B2 (en)	2014-04-03	2019-10-01	Invictus Oncology Pvt. Ltd.	Supramolecular combinatorial therapeutics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2601675B1 (fr) *	1986-07-17	1988-09-23	Rhone Poulenc Sante	Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2629818B1 (fr) *	1988-04-06	1990-11-16	Centre Nat Rech Scient	Procede de preparation du taxol
FR2629819B1 (fr) *	1988-04-06	1990-11-16	Rhone Poulenc Sante	Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii

1991
- 1991-07-10 FR FR9108673A patent/FR2678930B1/fr not_active Expired - Fee Related
1992
- 1992-07-08 PL PL92302030A patent/PL169780B1/pl unknown
- 1992-07-08 EP EP92401958A patent/EP0522958A1/fr active Pending
- 1992-07-08 DE DE69207194T patent/DE69207194T2/de not_active Expired - Lifetime
- 1992-07-08 ES ES92915477T patent/ES2081120T3/es not_active Expired - Lifetime
- 1992-07-08 JP JP05502037A patent/JP3085710B2/ja not_active Expired - Lifetime
- 1992-07-08 AU AU23280/92A patent/AU662346B2/en not_active Expired
- 1992-07-08 SK SK17-94A patent/SK281560B6/sk not_active IP Right Cessation
- 1992-07-08 KR KR1019940700046A patent/KR100206458B1/ko not_active Expired - Lifetime
- 1992-07-08 DK DK92915477.1T patent/DK0593641T3/da active
- 1992-07-08 WO PCT/FR1992/000649 patent/WO1993001179A1/fr not_active Ceased
- 1992-07-08 CA CA002111319A patent/CA2111319C/fr not_active Expired - Lifetime
- 1992-07-08 EP EP92915477A patent/EP0593641B1/fr not_active Expired - Lifetime
- 1992-07-08 AT AT92915477T patent/ATE132145T1/de active
- 1992-07-08 RU RU9294016161A patent/RU2088578C1/ru active
- 1992-07-08 CZ CZ9431A patent/CZ281288B6/cs not_active IP Right Cessation
- 1992-07-08 ZA ZA925098A patent/ZA925098B/xx unknown
- 1992-07-08 HU HU9400062A patent/HU217115B/hu unknown
- 1992-07-09 IE IE922234A patent/IE73637B1/en not_active IP Right Cessation
- 1992-07-09 NZ NZ243491A patent/NZ243491A/en not_active IP Right Cessation
- 1992-07-09 MX MX9204029A patent/MX9204029A/es unknown
- 1992-07-10 YU YU68792A patent/YU49175B/sh unknown
1993
- 1993-12-08 NO NO934485A patent/NO302521B1/no not_active IP Right Cessation
- 1993-12-08 NO NO934485D patent/NO934485D0/no unknown
1994
- 1994-01-07 FI FI940075A patent/FI109792B/fi not_active IP Right Cessation
1995
- 1995-07-06 US US08/498,613 patent/US5578739A/en not_active Expired - Lifetime
- 1995-12-28 GR GR950402328T patent/GR3018543T3/el unknown

Also Published As

Publication number	Publication date
RU2088578C1 (ru)	1997-08-27
US5578739A (en)	1996-11-26
NO934485D0 (no)	1993-12-08
JP3085710B2 (ja)	2000-09-11
GR3018543T3 (en)	1996-03-31
DE69207194T2 (de)	1996-09-05
SK281560B6 (sk)	2001-05-10
HUT66018A (en)	1994-08-29
FI940075A0 (fi)	1994-01-07
DE69207194D1 (de)	1996-02-08
DK0593641T3 (da)	1996-01-29
AU662346B2 (en)	1995-08-31
FI109792B (fi)	2002-10-15
MX9204029A (es)	1993-01-01
WO1993001179A1 (fr)	1993-01-21
ES2081120T3 (es)	1996-02-16
CZ281288B6 (cs)	1996-08-14
YU68792A (sh)	1995-10-03
FR2678930B1 (fr)	1995-01-13
SK1794A3 (en)	1994-11-09
PL169780B1 (pl)	1996-08-30
CA2111319A1 (fr)	1993-01-21
ZA925098B (en)	1993-04-28
EP0593641B1 (fr)	1995-12-27
EP0593641A1 (fr)	1994-04-27
EP0522958A1 (fr)	1993-01-13
IE73637B1 (en)	1997-06-18
HU217115B (hu)	1999-11-29
NO934485L (no)	1993-12-08
CA2111319C (fr)	2003-04-08
HU9400062D0 (en)	1994-05-30
NZ243491A (en)	1995-05-26
FR2678930A1 (fr)	1993-01-15
NO302521B1 (no)	1998-03-16
KR100206458B1 (ko)	1999-07-01
AU2328092A (en)	1993-02-11
YU49175B (sh)	2004-07-15
CZ3194A3 (en)	1994-04-13
JPH06509082A (ja)	1994-10-13
ATE132145T1 (de)	1996-01-15
IE922234A1 (en)	1993-01-13

Publication	Publication Date	Title
FI940075L (fi)	1994-01-07	Menetelmä bakkatiini-III- ja 10-desasetyylibakkatiini-III-johdannaisten valmistamiseksi
FI943749L (fi)	1995-02-18	Taksaanijohdannaisten fosfono-oksimetyylieetterit
FI981590A7 (fi)	1998-07-10	Uudet taksaanijohdannaiset
FI935821L (fi)	1994-06-25	Taksaanijohdannaisten fosfonooksimetyyliestereitä
FI951595L (fi)	1995-04-04	Menetelmä taksaanijohdannaisten valmistamiseksi
FI951591L (fi)	1995-04-04	Menetelmä taksaanijohdannaisten valmistamiseksi
FI951592A7 (fi)	1995-04-04	Menetelmä taksaanijohdannaisten valmistamiseksi
FI924678A7 (fi)	1993-04-16	Taksolin vesiliukoiset johdannaiset
FI925737A7 (fi)	1993-06-20	Menetelmä uusien terapeuttisesti käyttökelpoisten indol-3-yylialkyylipiperatsiinijohdannaisten valmistamiseksi
FI930623A7 (fi)	1993-08-15	Roerpigg med genomskinlig kanyl och foerfarande foer anvaendning av densamma
FI945441A0 (fi)	1994-11-18	Uusi menetelmä 7beta-substituoitu-4-atsa-5alfa-androstan-3-onien valmistamiseksi
FI943643A7 (fi)	1994-08-05	Menetelmä taksaanijohdannaisten valmistamiseksi
FI933168L (fi)	1994-01-14	Foerfarande foer framstaellning av polyesterpolyuretanmjukskumplast med liten imbildning och anvaendning av dessa i fordon
FI953645A7 (fi)	1995-09-27	Menetelmä taksaanijohdannaisten valmistamiseksi sekä niiden B-laktaami nivälituotteet
FI952059A7 (fi)	1995-04-28	Menetelmä taksaanijohdannaisten valmistamiseksi
NO307967B1 (no)	2000-06-26	FremgangsmÕte og mellomprodukter for fremstilling av benzopyranforbindelser
FI933222L (fi)	1994-01-16	Foerfarande foer framstaellning av vaeteperoxid med direkt syntes fraon vaete och syre
FI933598A0 (fi)	1993-08-13	Anordning och foerfarande foer direkt fasdigitering
NO940027D0 (no)	1994-01-04	Fremgangsmaate for fremstilling av derivater av _fenylisoserin og derivatenes anvendelse
FI944190A7 (fi)	1994-09-12	Menetelmä taksaanijohdannaisten valmistamiseksi
NO179517C (no)	1996-10-23	Fremgangsmåte for fremstilling av 8-klorkinolonderivater
NO941056L (no)	1994-09-26	Fremgangsmåte for fremstilling av organoklorsilaner
FI913464A7 (fi)	1992-01-21	Menetelmä 1-hydroksimetyylipyratsolien valmistamiseksi
NO940247D0 (no)	1994-01-24	Fremgangsmaate for fremstilling av 13 -cinnamoyl baccatin III eller 10-deacetyl baccatin III
FI923866A7 (fi)	1992-08-28	Menetelmä 1-hydroksialkyyli-5-nitroimidatsolien valmistamiseksi

Legal Events

Date	Code	Title	Description
2012-08-10	MA	Patent expired