[go: up one dir, main page]

FI946127A7 - Menetelmä alukkeen pidentämiseksi yhdellä nukleotidilla spesifisten al leelien detektoimiseksi, ja testipakkaus näiden menetelmien suorittami seksi - Google Patents

Menetelmä alukkeen pidentämiseksi yhdellä nukleotidilla spesifisten al leelien detektoimiseksi, ja testipakkaus näiden menetelmien suorittami seksi Download PDF

Info

Publication number
FI946127A7
FI946127A7 FI946127A FI946127A FI946127A7 FI 946127 A7 FI946127 A7 FI 946127A7 FI 946127 A FI946127 A FI 946127A FI 946127 A FI946127 A FI 946127A FI 946127 A7 FI946127 A7 FI 946127A7
Authority
FI
Finland
Prior art keywords
nucleotide
primer
detection
extending
methods
Prior art date
Application number
FI946127A
Other languages
English (en)
Swedish (sv)
Other versions
FI946127L (fi
FI946127A0 (fi
Inventor
Nurit Eyal
Original Assignee
Diagenetics Gamidor Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL10238292A external-priority patent/IL102382A/en
Application filed by Diagenetics Gamidor Ltd filed Critical Diagenetics Gamidor Ltd
Publication of FI946127A0 publication Critical patent/FI946127A0/fi
Publication of FI946127L publication Critical patent/FI946127L/fi
Publication of FI946127A7 publication Critical patent/FI946127A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4712—Cystic fibrosis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/102—Mutagenizing nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6853—Nucleic acid amplification reactions using modified primers or templates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6858—Allele-specific amplification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/686—Polymerase chain reaction [PCR]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6869—Methods for sequencing
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Pulmonology (AREA)
  • Plant Pathology (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
FI946127A 1992-07-02 1993-07-01 Menetelmä alukkeen pidentämiseksi yhdellä nukleotidilla spesifisten al leelien detektoimiseksi, ja testipakkaus näiden menetelmien suorittami seksi FI946127A7 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IL10238292A IL102382A (en) 1992-07-02 1992-07-02 Method for detecting nucleotide sequences and test kit therefor
US91987292A 1992-07-27 1992-07-27
PCT/US1993/006364 WO1994001447A1 (en) 1992-07-02 1993-07-01 Methods of single nucleotide primer extension to detect specific alleles and kits therefor

Publications (3)

Publication Number Publication Date
FI946127A0 FI946127A0 (fi) 1994-12-28
FI946127L FI946127L (fi) 1995-02-20
FI946127A7 true FI946127A7 (fi) 1995-02-20

Family

ID=26322472

Family Applications (1)

Application Number Title Priority Date Filing Date
FI946127A FI946127A7 (fi) 1992-07-02 1993-07-01 Menetelmä alukkeen pidentämiseksi yhdellä nukleotidilla spesifisten al leelien detektoimiseksi, ja testipakkaus näiden menetelmien suorittami seksi

Country Status (9)

Country Link
EP (1) EP0648222B1 (fi)
JP (1) JPH08507198A (fi)
AT (1) ATE231881T1 (fi)
AU (1) AU4770393A (fi)
CA (1) CA2139433A1 (fi)
DE (1) DE69332666T2 (fi)
ES (1) ES2191666T3 (fi)
FI (1) FI946127A7 (fi)
WO (1) WO1994001447A1 (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19515552A1 (de) * 1995-04-27 1996-10-31 Europ Lab Molekularbiolog Simultane Sequenzierung von Nukleinsäuren
US5882867A (en) * 1995-06-07 1999-03-16 Dade Behring Marburg Gmbh Detection of nucleic acids by formation of template-dependent product
US5876936A (en) * 1997-01-15 1999-03-02 Incyte Pharmaceuticals, Inc. Nucleic acid sequencing with solid phase capturable terminators
US6073209A (en) * 1997-03-31 2000-06-06 Ark Research Corporation Data storage controller providing multiple hosts with access to multiple storage subsystems
US6268136B1 (en) 1997-06-16 2001-07-31 Exact Science Corporation Methods for stool sample preparation
CA2245039A1 (en) 1998-08-13 2000-02-13 Vito Scalia Primer-specific and mispair extension assay for identifying gene variation
AU1479200A (en) * 1998-11-23 2000-06-13 Exact Laboratories, Inc. Methods for detecting lower-frequency molecules
EP1131468A2 (en) * 1998-11-23 2001-09-12 Exact Sciences Corporation Primer extension methods utilizing donor and acceptor molecules for detecting nucleic acids
US6964846B1 (en) 1999-04-09 2005-11-15 Exact Sciences Corporation Methods for detecting nucleic acids indicative of cancer
US6586177B1 (en) 1999-09-08 2003-07-01 Exact Sciences Corporation Methods for disease detection
US6849403B1 (en) 1999-09-08 2005-02-01 Exact Sciences Corporation Apparatus and method for drug screening
JP3565752B2 (ja) * 1999-11-02 2004-09-15 株式会社海洋バイオテクノロジー研究所 Ｄｎａジャイレース遺伝子中に存在する特徴的な塩基配列を用いた遅発育性マイコバクテリアの同定法及び特異的検出法
US6919174B1 (en) 1999-12-07 2005-07-19 Exact Sciences Corporation Methods for disease detection
AU4714201A (en) 1999-12-07 2001-06-18 Exact Sciences Corporation Supracolonic aerodigestive neoplasm detection
AU785211B2 (en) * 1999-12-10 2006-11-02 Johannes Dapprich Method for selectively isolating a nucleic acid
ATE399882T1 (de) * 2002-11-07 2008-07-15 Yoichi Matsubara Verfahren zum genmutationsnachweis
GB0406864D0 (en) 2004-03-26 2004-04-28 Qiagen As Nucleic acid sequencing
US20060040300A1 (en) 2004-08-09 2006-02-23 Generation Biotech, Llc Method for nucleic acid isolation and amplification
WO2006047787A2 (en) 2004-10-27 2006-05-04 Exact Sciences Corporation Method for monitoring disease progression or recurrence
US9777314B2 (en) 2005-04-21 2017-10-03 Esoterix Genetic Laboratories, Llc Analysis of heterogeneous nucleic acid samples

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69033179T3 (de) * 1989-02-13 2005-01-27 Geneco Pty. Ltd. Nachweis einer nukleinsäuresequenz oder einer änderung darin
FR2650840B1 (fr) * 1989-08-11 1991-11-29 Bertin & Cie Procede rapide de detection et/ou d'identification d'une seule base sur une sequence d'acide nucleique, et ses applications
US5137806A (en) * 1989-12-11 1992-08-11 Board Of Regents, The University Of Texas System Methods and compositions for the detection of sequences in selected DNA molecules
IL97222A (en) * 1990-02-16 1995-08-31 Orion Yhtymae Oy Method and reagent for determining specific nucleotide variations
US6004744A (en) * 1991-03-05 1999-12-21 Molecular Tool, Inc. Method for determining nucleotide identity through extension of immobilized primer
WO1992016657A1 (en) * 1991-03-13 1992-10-01 E.I. Du Pont De Nemours And Company Method of identifying a nucleotide present at a defined position in a nucleic acid

Also Published As

Publication number Publication date
FI946127L (fi) 1995-02-20
AU4770393A (en) 1994-01-31
ATE231881T1 (de) 2003-02-15
WO1994001447A1 (en) 1994-01-20
JPH08507198A (ja) 1996-08-06
FI946127A0 (fi) 1994-12-28
EP0648222B1 (en) 2003-01-29
EP0648222A1 (en) 1995-04-19
DE69332666T2 (de) 2003-12-18
EP0648222A4 (en) 1999-03-17
CA2139433A1 (en) 1994-01-20
DE69332666D1 (de) 2003-03-06
ES2191666T3 (es) 2003-09-16

Similar Documents

Publication Publication Date Title
FI946127A7 (fi) Menetelmä alukkeen pidentämiseksi yhdellä nukleotidilla spesifisten al leelien detektoimiseksi, ja testipakkaus näiden menetelmien suorittami seksi
FI950487L (fi) Menetelmä, reagenssi ja testipakkaus nukleiinihapposekvenssien totamiseksi ja monistamiseksi
DE68918657D1 (de) Verfahren zum Nachweis spezifischer Nukleinsäuresequenzen.
DK0701627T3 (da) Nukleinsyreanalogafprøvningsmetoder
BG87585A (bg) Метод за откриване на нуклеотидни последователности
DE69520330D1 (de) Verfahren zum Nachweis von spezifischen Nukleinsäuresequenzen
FI904200A7 (fi) Intronisekvenssianalyysimenetelmä vierekkäisten ja toisistaan kaukana olevien lokusalleellien tunnistamiseksi haplotyypeiksi
DE69434255D1 (de) Nukleinsäuresonde zum nachweis von lactobacillus
DE3775224D1 (de) Protonenleitergassensor und verfahren zum gasnachweis unter benutzung desselben.
AU5479599A (en) Methods and systems for sequencing dna by distinguishing the decay times of fluorescent probes
DE69422687D1 (de) Biosensor zur hämatokritbestimmung
DK0566751T3 (da) DNA-påvisningsmetode
NO971523D0 (no) Stålrörforbindelse med höy rivingsmotstand, samt fremgangsmåte for overflatebehandling av denne
DE3851951D1 (de) Amperometrische Messmethode Amperometrische Messmethode.
DE69411321D1 (de) Vorrichtung zum Nachweis von Fluoreszenz
FI973122L (fi) Menetelmä ja yhdisteitä analysoitavien aineiden detektoimiseksi magnetorelaksometrisesti ja niiden käyttö
FI915150A7 (fi) Menetelmät, reagenssit ja testikäyttöpakkaukset biologisten yksiköiden alapopulaatioiden määrittämiseksi
FI901916A7 (fi) Diagnostinen testipakkaus, alukekoostumus, ja näiden käyttö nukleiinihappojen replikaatioon tai havaitsemiseen
DE4403348B8 (de) Verfahren zur Detektion von Fehlzündungen
DE59204440D1 (de) Verfahren zur Erkennung von Verbrennungsaussetzern.
FI962340L (fi) Nukleiinihappojen suojaaminen ja analyysimenetelmät
DE3888653D1 (de) Verfahren und Testsatz zum Nachweis einer Nukleinsäure-Sequenz.
DE68924591D1 (de) DNS-Nachweis unter Verwendung ladungsneutraler Probenstränge.
DE69930404D1 (de) Methode zum nachweis von analyten
DE69018625D1 (de) Verfahren zum aufkonzentrieren von chlorgas.

Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: DIAGENETICS GAMIDOR LTD

FD Application lapsed