FI945313L - Parannetun biokäytettävyyden omaavat tabletit, jotka sisältävät dikloorimetyleenifosfonihappoa vaikuttavana aineena - Google Patents

Parannetun biokäytettävyyden omaavat tabletit, jotka sisältävät dikloorimetyleenifosfonihappoa vaikuttavana aineena Download PDF

Info

Publication number: FI945313L
Authority: FI; Finland
Prior art keywords: dichloromethylenephosphonic; tablets; acid; active ingredient; improved bioavailability
Prior art date: 1993-05-15

Application number

FI945313A

Other languages

English (en)

Swedish (sv)

Other versions

FI111519B (fi

FI945313A0 (fi

Inventor

Walter Preis

Bernd Muesel

Guenter Neugebauer

Rolf-Dieter Gabel

Original Assignee

Boehringer Mannheim Gmbh

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-05-15

Filing date

1994-11-11

Publication date

1994-12-13

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25927331&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI945313(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1993-05-15 Priority claimed from DE9307393U external-priority patent/DE9307393U1/de

1993-07-02 Priority claimed from DE19934322057 external-priority patent/DE4322057A1/de

1994-11-11 Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh

1994-11-11 Publication of FI945313A0 publication Critical patent/FI945313A0/fi

1994-12-13 Publication of FI945313L publication Critical patent/FI945313L/fi

2003-08-15 Application granted granted Critical

2003-08-15 Publication of FI111519B publication Critical patent/FI111519B/fi

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
- A61K47/38—Cellulose; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Chemistry (AREA)
Physical Education & Sports Medicine (AREA)
Hematology (AREA)
Obesity (AREA)
Orthopedic Medicine & Surgery (AREA)
Diabetes (AREA)
Rheumatology (AREA)
Inorganic Chemistry (AREA)
Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

FI945313A 1993-05-15 1994-11-11 Menetelmä sellaisen tabletin valmistamiseksi, joka sisältävää vaikuttavana aineena dikloorimetyleenifosfonihappoa FI111519B (fi)

Applications Claiming Priority (6)

Application Number	Priority Date	Filing Date	Title
DE9307393		1993-05-15
DE9307393U DE9307393U1 (de)	1993-05-15	1993-05-15	Tablette mit verbesserter Bioverfügbarkeit, enthaltend Dichlormethylendiphosphonsäure als Wirkstoff
DE4322057		1993-07-02
DE19934322057 DE4322057A1 (de)	1993-07-02	1993-07-02	Tablette mit verbesserter Bioverfügbarkeit enthaltend Dichlormethylendiphosphonsäure als Wirkstoff
EP9301967		1993-07-24
PCT/EP1993/001967 WO1994026310A1 (de)	1993-05-15	1993-07-24	Tablette mit verbesserter bioverfügbarkeit enthaltend dichlormethylendiphosphonsäure als wirkstoff

Publications (3)

Publication Number	Publication Date
FI945313A0 FI945313A0 (fi)	1994-11-11
FI945313L true FI945313L (fi)	1994-12-13
FI111519B FI111519B (fi)	2003-08-15

Family

ID=25927331

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI945313A FI111519B (fi)	1993-05-15	1994-11-11	Menetelmä sellaisen tabletin valmistamiseksi, joka sisältävää vaikuttavana aineena dikloorimetyleenifosfonihappoa

Country Status (25)

Country	Link
US (1)	US5650168A (fi)
EP (2)	EP0625355B2 (fi)
JP (1)	JP3699110B2 (fi)
KR (1)	KR100263284B1 (fi)
CN (1)	CN1041797C (fi)
AT (2)	ATE128363T1 (fi)
AU (1)	AU687744B2 (fi)
BR (1)	BR9307859A (fi)
CA (1)	CA2162470C (fi)
CZ (1)	CZ287984B6 (fi)
DE (1)	DE59300688D1 (fi)
DK (1)	DK0625355T5 (fi)
ES (1)	ES2065313T5 (fi)
FI (1)	FI111519B (fi)
GR (2)	GR940300095T1 (fi)
HU (1)	HU220872B1 (fi)
IL (1)	IL106743A (fi)
NO (1)	NO307548B1 (fi)
NZ (1)	NZ254765A (fi)
PL (1)	PL173026B1 (fi)
RU (1)	RU2134103C1 (fi)
SK (1)	SK281193B6 (fi)
TW (1)	TW350772B (fi)
UA (1)	UA39884C2 (fi)
WO (1)	WO1994026310A1 (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FI94926C (fi)	1993-11-12	1995-11-27	Leiras Oy	Menetelmä klodronaattivalmisteen valmistamiseksi
DE19615812A1 (de) *	1996-04-20	1997-10-23	Boehringer Mannheim Gmbh	Pharmazeutische Zubereitung enthaltend Diphosphonsäuren zur oralen Applikation
DE19719680A1 (de)	1997-05-09	1998-11-19	Boehringer Mannheim Gmbh	Verwendung von Diphosphonsäuren zur präventiven Behandlung von Spätfolgen bei Harnblasenerweiterung oder Harnblasenersatz
FI109088B (fi) *	1997-09-19	2002-05-31	Leiras Oy	Tabletti ja menetelmä sen valmistamiseksi
EP0998932A1 (de)	1998-10-09	2000-05-10	Boehringer Mannheim Gmbh	Feste pharmazeutische Darreichungsform enthaltend Diphosphonsäure oder deren Salze und Verfahren zu ihrer Herstellung
SE9901272D0 (sv) *	1999-04-09	1999-04-09	Astra Ab	New improved formulation
CZ20002567A3 (cs) *	2000-07-11	2001-12-12	Léčiva, A.S.	Tableta vyrobitelná přímým tabletováním, obsahující aktivní látku kyselinu 4-amino-1-hydroxybutyliden-1,1-bisfosfonovou, a způsob její výroby
RU2192848C1 (ru) *	2001-10-30	2002-11-20	Закрытое акционерное общество "ВЕРОФАРМ"	Противорвотное средство
US10226428B2 (en)	2003-09-19	2019-03-12	Sun Pharma Advanced Research Company Ltd.	Oral drug delivery system
WO2005039481A2 (en) *	2003-09-19	2005-05-06	Sun Pharmaceutical Industries Limited	Oral drug delivery system
US10213387B2 (en)	2003-09-19	2019-02-26	Sun Pharma Advanced Research Company Ltd.	Oral drug delivery system
US7151400B2 (en) *	2004-07-13	2006-12-19	Taiwan Semiconductor Manufacturing Company, Ltd.	Boost-biased level shifter
CN100370972C (zh) *	2006-01-10	2008-02-27	北京申科联华科技有限公司	一种具有益气养阴、活血复脉功效的片剂及制备方法
KR20100045450A (ko) *	2007-08-02	2010-05-03	데이진 화-마 가부시키가이샤	골 대사 이상에서 기인하는 질환의 예방제 또는 치료제
BRPI0908114A2 (pt) *	2008-02-15	2015-10-06	Sun Pharma Advanced Res Co Ltd	tabuleta oral de liberação controlada
CN118370733B (zh) *	2024-06-21	2024-10-01	山东新时代药业有限公司	一种钙代谢调节药物氯膦酸二钠片及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PH9776A (en) *	1967-12-11	1976-03-17	M Francis	Compositions for inhibiting anomalous deposition and mobilization of calcium phosphate in animal tissue and method of use
DE2813121A1 (de) *	1977-03-29	1978-10-12	Procter & Gamble	Verwendung von dichlormethan-diphosphonatverbindungen bei der bekaempfung von collagen-erkrankungen und zur wundheilung
US4634691A (en) *	1980-10-07	1987-01-06	The Procter & Gamble Company	Method for inhibiting tumor metastasis
US4517179A (en) *	1983-04-29	1985-05-14	Pennwalt Corporation	Rapid dissolving, uniform drug compositions and their preparation
SU1437023A1 (ru) *	1986-01-02	1988-11-15	Всесоюзный научно-исследовательский институт химии и технологии лекарственных средств	Антацидное средство "Кальмагин
SE457326B (sv) *	1986-02-14	1988-12-19	Lejus Medical Ab	Foerfarande foer framstaellning av en snabbt soenderfallande kaerna innehaallande bl a mikrokristallin cellulosa
ATE60711T1 (de) *	1986-12-20	1991-02-15	Boehringer Mannheim Gmbh	Clodronat-haltige arzneimittel und verfahren zur herstellung derselben.
DE3804686A1 (de) *	1988-02-15	1989-08-24	Henkel Kgaa	Arzneimittel mit einer kombination von cytostatika bzw. hormontherapeutika und phosphonoderivaten
FR2629716B1 (fr) *	1988-04-07	1991-07-19	Sanofi Sa	Composition pharmaceutique pour administration orale a base d'un derive d'acide diphosphonique
FI83421C (fi) †	1989-06-21	1991-07-10	Huhtamaeki Oy	Foerfarande foer framstaellning av farmakologiskt anvaendbara metylenbisfosfonsyraderivat.
RU2113848C1 (ru) *	1991-02-26	1998-06-27	Норвич Итон Фармасьютикалз, Инк.	Способ лечения остеопороза, композиция для лечения остеопороза, применение активно действующего на кости фосфоната и эстрогенного гормона для лечения остеопороза
SE501389C2 (sv) *	1992-04-24	1995-01-30	Leiras Oy	Farmaceutiskt preparat och förfarande för dess framställning
JPH08505142A (ja) *	1992-12-23	1996-06-04	メルクエンドカンパニーインコーポレーテッド	骨損失を治療及び予防するためのビスホスホネート／エストロゲン療法

1993
- 1993-07-24 SK SK48-95A patent/SK281193B6/sk not_active IP Right Cessation
- 1993-07-24 CZ CZ1995100A patent/CZ287984B6/cs not_active IP Right Cessation
- 1993-07-24 DK DK93111827T patent/DK0625355T5/da active
- 1993-07-24 HU HU9403160A patent/HU220872B1/hu unknown
- 1993-07-24 RU RU95121748A patent/RU2134103C1/ru active
- 1993-07-24 ES ES93111827T patent/ES2065313T5/es not_active Expired - Lifetime
- 1993-07-24 EP EP93111827A patent/EP0625355B2/de not_active Expired - Lifetime
- 1993-07-24 NZ NZ254765A patent/NZ254765A/en not_active IP Right Cessation
- 1993-07-24 EP EP93917636A patent/EP0697890A1/de not_active Withdrawn
- 1993-07-24 CA CA002162470A patent/CA2162470C/en not_active Expired - Lifetime
- 1993-07-24 PL PL93307133A patent/PL173026B1/pl unknown
- 1993-07-24 KR KR1019950705094A patent/KR100263284B1/ko not_active Expired - Lifetime
- 1993-07-24 BR BR9307859A patent/BR9307859A/pt not_active Application Discontinuation
- 1993-07-24 WO PCT/EP1993/001967 patent/WO1994026310A1/de not_active Ceased
- 1993-07-24 AU AU47020/93A patent/AU687744B2/en not_active Expired
- 1993-07-24 UA UA95114854A patent/UA39884C2/uk unknown
- 1993-07-24 JP JP51843194A patent/JP3699110B2/ja not_active Expired - Fee Related
- 1993-07-24 DE DE59300688T patent/DE59300688D1/de not_active Expired - Lifetime
- 1993-07-24 US US08/537,853 patent/US5650168A/en not_active Expired - Lifetime
- 1993-07-24 AT AT93111827T patent/ATE128363T1/de active
- 1993-08-19 IL IL10674393A patent/IL106743A/en not_active IP Right Cessation
- 1993-09-10 TW TW082106635A patent/TW350772B/zh not_active IP Right Cessation
- 1993-09-23 CN CN93118149A patent/CN1041797C/zh not_active Expired - Lifetime
1994
- 1994-05-13 AT AT0007494U patent/AT128U1/de not_active IP Right Cessation
- 1994-11-11 FI FI945313A patent/FI111519B/fi not_active IP Right Cessation
- 1994-11-17 NO NO944405A patent/NO307548B1/no not_active IP Right Cessation
1995
- 1995-01-31 GR GR940300095T patent/GR940300095T1/el unknown
- 1995-09-28 GR GR950402574T patent/GR3017547T3/el unknown

Also Published As

Publication number	Publication date
DE59300688D1 (de)	1995-11-02
SK281193B6 (sk)	2001-01-18
CN1095267A (zh)	1994-11-23
PL307133A1 (en)	1995-05-02
FI111519B (fi)	2003-08-15
NO307548B1 (no)	2000-04-25
JPH08509697A (ja)	1996-10-15
JP3699110B2 (ja)	2005-09-28
GR3017547T3 (en)	1995-12-31
GR940300095T1 (en)	1995-01-31
DK0625355T4 (da)	2003-10-06
AU687744B2 (en)	1998-03-05
ATE128363T1 (de)	1995-10-15
NO944405L (no)	1994-11-24
WO1994026310A1 (de)	1994-11-24
KR960702322A (ko)	1996-04-27
DK0625355T5 (da)	2003-12-01
BR9307859A (pt)	1996-01-09
CN1041797C (zh)	1999-01-27
CZ10095A3 (en)	1995-10-18
TW350772B (en)	1999-01-21
UA39884C2 (uk)	2001-07-16
AT128U1 (de)	1995-03-27
DK0625355T3 (da)	1995-12-27
KR100263284B1 (ko)	2000-08-01
SK4895A3 (en)	1997-01-08
PL173026B1 (pl)	1998-01-30
ES2065313T1 (es)	1995-02-16
ES2065313T5 (es)	2004-01-01
NZ254765A (en)	1997-02-24
IL106743A (en)	1999-11-30
ES2065313T3 (es)	1995-12-01
HUT70214A (en)	1995-09-28
CA2162470C (en)	1998-06-16
HU9403160D0 (en)	1995-02-28
EP0625355B1 (de)	1995-09-27
EP0625355B2 (de)	2003-06-25
CZ287984B6 (cs)	2001-03-14
EP0697890A1 (de)	1996-02-28
AU4702093A (en)	1994-12-12
FI945313A0 (fi)	1994-11-11
US5650168A (en)	1997-07-22
HU220872B1 (en)	2002-06-29
NO944405D0 (no)	1994-11-17
IL106743A0 (en)	1993-12-08
RU2134103C1 (ru)	1999-08-10
EP0625355A1 (de)	1994-11-23
CA2162470A1 (en)	1994-11-24

Publication	Publication Date	Title
IT8921118A0 (it)	1989-07-07	Composizione per aerosol comprendente nitroglicerina come ingrediente attivo.
ITRM920361A1 (it)	1993-11-12	Composizioni farmaceutiche contenenti un composto allilamminico quale principio attivo.
FI903382A0 (fi)	1990-07-04	Topiskt anbringbara farmaceutiska preparat.
KR970006279A (ko)	1997-02-19	약제학적 활성 성분으로서의 6-디메틸아미노메틸-1-페닐-사이클로헥산 화합물
DE59402194D1 (de)	1997-04-30	Fungizide Wirkstoffkombinationen
FI954990L (fi)	1995-11-23	Aktiiviainetta sisältävä transdermaalinen valmiste
DE59408221D1 (de)	1999-06-17	Fungizide Wirkstoffkombinationen
DK175487D0 (da)	1987-04-06	Farmaceutisk aktive 2-thiomethyl-substitueret-1,4-dihydro-pyridiner
DE69014498D1 (de)	1995-01-12	Hyposensibilisierende wirksame Substanz.
FI904444A0 (fi)	1990-09-10	Aktiva limkompositioner.
FI945313L (fi)	1994-12-13	Parannetun biokäytettävyyden omaavat tabletit, jotka sisältävät dikloorimetyleenifosfonihappoa vaikuttavana aineena
FI873630A0 (fi)	1987-08-21	Stabilt farmaceutiskt preparat.
FI961282L (fi)	1996-05-17	Transdermaalinen terapeuttinen systeemi, jossa on asetyylisalisyylihappo vaikuttavana aineena
ITFI930083A1 (it)	1994-10-26	Composti pirrol-amidinici, processi di preparazione e composizioni farmaceutiche che li contengono.
TR28760A (tr)	1997-02-28	Dihalopropen bilesigi, adi gecen dihalopropen bilesigi aktif unsur olarak ihtiva eden böcek öldürücü/akar öldürücü ve adi gecen dihalopropen bilesigin üretiminde kullanilmak üzere olan ara bilesik.
FI874382A0 (fi)	1987-10-06	Farmaceutiska preparat.
FI900024A7 (fi)	1990-07-06	Pyrrolylfenyl-substituerade hydroxamsyraderivat.
FI941149L (fi)	1994-12-22	2,4-diamino-3-hydroksikarboksyylihapon johdannaisia
FI922720A0 (fi)	1992-06-12	Farmakologiskt aktiva amidkarboxylatderivat.
IT8920405A0 (it)	1989-05-08	Aminoimidazopiridine farmacologicamente attive.
DE59008309D1 (de)	1995-03-02	Fungizide Wirkstoffkombinationen.
FI906104L (fi)	1991-06-14	Naftylsulfonylalkansyraderivat.
FI923371A0 (fi)	1992-07-24	En farmaceutisk formulation.
FI883747A0 (fi)	1988-08-12	Topiskt anvaendbara farmaceutiska preparat.
ATE121078T1 (de)	1995-04-15	Propensäurederivate.

Legal Events

Date	Code	Title	Description
1999-05-30	HC	Name/ company changed in application	Owner name: ROCHE DIAGNOSTICS GMBH
2012-03-27	PC	Transfer of assignment of patent	Owner name: RIEMSER ARZNEIMITTEL AG
2013-08-16	MA	Patent expired