FI932518L - Antagonister av angiotensin ii - Google Patents
Antagonister av angiotensin ii Download PDFInfo
- Publication number
- FI932518L FI932518L FI932518A FI932518A FI932518L FI 932518 L FI932518 L FI 932518L FI 932518 A FI932518 A FI 932518A FI 932518 A FI932518 A FI 932518A FI 932518 L FI932518 L FI 932518L
- Authority
- FI
- Finland
- Prior art keywords
- antagonister
- angiotensin
- Prior art date
Links
- 102000005862 Angiotensin II Human genes 0.000 title 1
- 101800000733 Angiotensin-2 Proteins 0.000 title 1
- CZGUSIXMZVURDU-JZXHSEFVSA-N Ile(5)-angiotensin II Chemical compound C([C@@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC=1NC=NC=1)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC=1C=CC=CC=1)C([O-])=O)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=[NH2+])NC(=O)[C@@H]([NH3+])CC([O-])=O)C(C)C)C1=CC=C(O)C=C1 CZGUSIXMZVURDU-JZXHSEFVSA-N 0.000 title 1
- 229950006323 angiotensin ii Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06191—Dipeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US89285492A | 1992-06-03 | 1992-06-03 | |
| US08/049,916 US5612360A (en) | 1992-06-03 | 1993-04-20 | Angiotensin II antagonists |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI932518A0 FI932518A0 (fi) | 1993-06-02 |
| FI932518A7 FI932518A7 (fi) | 1993-12-04 |
| FI932518L true FI932518L (fi) | 1993-12-04 |
Family
ID=26727699
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI932518A FI932518L (fi) | 1992-06-03 | 1993-06-02 | Antagonister av angiotensin ii |
Country Status (21)
| Country | Link |
|---|---|
| US (4) | US5612360A (fi) |
| EP (1) | EP0574174B1 (fi) |
| JP (1) | JPH0680666A (fi) |
| KR (1) | KR940005617A (fi) |
| CN (1) | CN1101908A (fi) |
| AT (1) | ATE247107T1 (fi) |
| AU (1) | AU661396B2 (fi) |
| CA (1) | CA2097460A1 (fi) |
| CZ (1) | CZ104593A3 (fi) |
| DE (1) | DE69333138T2 (fi) |
| DK (1) | DK0574174T3 (fi) |
| ES (1) | ES2204898T3 (fi) |
| FI (1) | FI932518L (fi) |
| HU (1) | HUT64330A (fi) |
| IL (1) | IL105878A0 (fi) |
| MX (1) | MX9303263A (fi) |
| NO (1) | NO932004L (fi) |
| NZ (1) | NZ247770A (fi) |
| PL (1) | PL299177A1 (fi) |
| PT (1) | PT574174E (fi) |
| TW (1) | TW252109B (fi) |
Families Citing this family (114)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5612360A (en) * | 1992-06-03 | 1997-03-18 | Eli Lilly And Company | Angiotensin II antagonists |
| ATE208933T1 (de) * | 1994-04-29 | 2001-11-15 | Infineon Technologies Ag | Verfahren zur fuzzifizierung von an eingängen eines fuzzy-prozessors anliegenden eingangssignalen unter verwendung von eingangszugehörigkeitsfunktionen |
| FR2728570B1 (fr) * | 1994-12-23 | 1997-04-11 | Synthelabo | Derives de 1-oxo-2-(phenylsulfonylamino)pentylpiperidine, leur preparation et leur application en therapeutique |
| EP0758097B1 (en) * | 1995-01-25 | 2002-08-21 | Mitsubishi Chemical Corporation | Polymerizable composition for color filter |
| GB9518552D0 (en) * | 1995-09-11 | 1995-11-08 | Fujisawa Pharmaceutical Co | New heterocyclic compounds |
| ES2201299T3 (es) * | 1996-06-25 | 2004-03-16 | Pfizer Inc. | Derivados sustituidos de indazol y su uso como inhibidores de fosfodiesterasa (pde) de tipo iv y factor de necrosis tumoral (tnf)`. |
| US5977134A (en) * | 1996-12-05 | 1999-11-02 | Merck & Co., Inc. | Inhibitors of farnesyl-protein transferase |
| WO1998031363A1 (en) * | 1997-01-22 | 1998-07-23 | Eli Lilly And Company | Anti-viral compounds |
| ES2241151T3 (es) | 1997-06-26 | 2005-10-16 | Eli Lilly And Company | Agentes antitromboticos. |
| IL133800A0 (en) | 1997-07-03 | 2001-04-30 | Du Pont Pharm Co | Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders |
| FR2766822B1 (fr) * | 1997-07-30 | 2001-02-23 | Adir | Nouveaux derives de benzimidazole, de benzoxazole et de benzothiazole, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US6365589B1 (en) | 1998-07-02 | 2002-04-02 | Bristol-Myers Squibb Pharma Company | Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists |
| ITPD980169A1 (it) * | 1998-07-06 | 2000-01-06 | Fidia Advanced Biopolymers Srl | Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione. |
| ATE286511T1 (de) * | 1999-02-17 | 2005-01-15 | Pfizer Prod Inc | Fusionsproteine mit trägern welche eine doppelte immunantwort induzieren |
| EP1153613B1 (en) * | 1999-02-19 | 2010-11-10 | Takeda Pharmaceutical Company Limited | Percutaneous absorption preparations of compound having angiotensin ii receptor antagonism |
| AU777961B2 (en) * | 1999-06-22 | 2004-11-04 | Neurosearch A/S | Novel benzimidazole derivatives and pharmaceutical compositions comprising these compounds |
| US6534535B1 (en) | 1999-08-12 | 2003-03-18 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
| US6632815B2 (en) * | 1999-09-17 | 2003-10-14 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
| US6720317B1 (en) | 1999-09-17 | 2004-04-13 | Millennium Pharmaceuticals, Inc. | Inhibitors of factor Xa |
| US6844367B1 (en) * | 1999-09-17 | 2005-01-18 | Millennium Pharmaceuticals, Inc. | Benzamides and related inhibitors of factor Xa |
| YU54202A (sh) | 2000-01-18 | 2006-01-16 | Agouron Pharmaceuticals Inc. | Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije |
| HN2001000008A (es) | 2000-01-21 | 2003-12-11 | Inc Agouron Pharmaceuticals | Compuesto de amida y composiciones farmaceuticas para inhibir proteinquinasas, y su modo de empleo |
| AU2001245353A1 (en) | 2000-02-29 | 2001-09-12 | Cor Therapeutics, Inc. | Benzamides and related inhibitors of factor xa |
| EP1132381A1 (en) * | 2000-03-08 | 2001-09-12 | Cermol S.A. | Ester derivatives of dimethylpropionic acid and pharmaceutical compositions containing them |
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| DK1397130T3 (da) | 2001-06-20 | 2007-11-12 | Wyeth Corp | Substituerede indolsyrederivater som inhibitorer af plasminogenaktivatorinhibitor-1 (PAI-1) |
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| UA80453C2 (en) * | 2002-12-10 | 2007-09-25 | Derivatives of substituted dyhydropyranoindol-3,4-dion as inhibitors of plasminogen activator inhibitor-1 (pai-1) | |
| DK1569899T3 (da) * | 2002-12-10 | 2006-10-23 | Wyeth Corp | Substituerede 3-alkyl- og 3-arylalkyl-1H-indol-1-yl-eddikesyrederivater som inhibitorer af plasminogenaktivator-inhibitor-1 (PAI-1) |
| JP2006514637A (ja) * | 2002-12-10 | 2006-05-11 | ワイス | プラスミノーゲン活性化因子の阻害因子−1(pai−1)の阻害剤としての置換3−カルボニル−1h−インドール−1−イル酢酸誘導体 |
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| WO2005007627A1 (ja) * | 2003-07-18 | 2005-01-27 | Nihon Nohyaku Co., Ltd. | フェニルピリジン誘導体、その中間体及びこれを有効成分とする除草剤 |
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| US7163954B2 (en) * | 2003-09-25 | 2007-01-16 | Wyeth | Substituted naphthyl benzothiophene acids |
| US7411083B2 (en) * | 2003-09-25 | 2008-08-12 | Wyeth | Substituted acetic acid derivatives |
| US7420083B2 (en) * | 2003-09-25 | 2008-09-02 | Wyeth | Substituted aryloximes |
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| US7265148B2 (en) * | 2003-09-25 | 2007-09-04 | Wyeth | Substituted pyrrole-indoles |
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| JP2008513512A (ja) * | 2004-09-21 | 2008-05-01 | アサーシス, インク. | Crth2受容体拮抗作用を示すインドール酢酸およびこれらの使用 |
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| SE0402763D0 (sv) * | 2004-11-11 | 2004-11-11 | Astrazeneca Ab | Nitro indazole derivatives |
| SE0402762D0 (sv) * | 2004-11-11 | 2004-11-11 | Astrazeneca Ab | Indazole sulphonamide derivatives |
| ITPD20050056A1 (it) * | 2005-03-02 | 2006-09-03 | Fidia Farmaceutici | Derivati ammidici del'acido ialuronico in osteoartrosi |
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| CN102863432B (zh) | 2007-05-09 | 2016-09-07 | 沃泰克斯药物股份有限公司 | Cftr调节剂 |
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| SG186638A1 (en) | 2007-12-07 | 2013-01-30 | Vertex Pharma | Solid forms of 3-(6-(1-(2,2-difluorobenzo[d][1,3] dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl) benzoic acid |
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| PL2806859T3 (pl) | 2012-01-25 | 2019-11-29 | Vertex Pharma | Formulacje kwasu 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioksol-5- ilo)cyklopropanokarboksyamido)-3-metylopirydyn-2-ylo)benzoesowego |
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| PT3068392T (pt) | 2013-11-12 | 2021-05-14 | Vertex Pharma | Processo de preparação de composições farmacêuticas para o tratamento de doenças mediadas por condutância transmembrana da fibrose quística (cftr) |
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-
1993
- 1993-04-20 US US08/049,916 patent/US5612360A/en not_active Expired - Fee Related
- 1993-06-01 CZ CZ931045A patent/CZ104593A3/cs unknown
- 1993-06-01 HU HU9301602A patent/HUT64330A/hu unknown
- 1993-06-01 TW TW082104360A patent/TW252109B/zh active
- 1993-06-01 MX MX9303263A patent/MX9303263A/es unknown
- 1993-06-01 CA CA002097460A patent/CA2097460A1/en not_active Abandoned
- 1993-06-01 IL IL105878A patent/IL105878A0/xx unknown
- 1993-06-02 EP EP93304266A patent/EP0574174B1/en not_active Expired - Lifetime
- 1993-06-02 AU AU39986/93A patent/AU661396B2/en not_active Ceased
- 1993-06-02 NO NO932004A patent/NO932004L/no unknown
- 1993-06-02 DK DK93304266T patent/DK0574174T3/da active
- 1993-06-02 DE DE69333138T patent/DE69333138T2/de not_active Expired - Fee Related
- 1993-06-02 ES ES93304266T patent/ES2204898T3/es not_active Expired - Lifetime
- 1993-06-02 AT AT93304266T patent/ATE247107T1/de not_active IP Right Cessation
- 1993-06-02 NZ NZ247770A patent/NZ247770A/en unknown
- 1993-06-02 PT PT93304266T patent/PT574174E/pt unknown
- 1993-06-02 FI FI932518A patent/FI932518L/fi not_active Application Discontinuation
- 1993-06-02 KR KR1019930009916A patent/KR940005617A/ko not_active Withdrawn
- 1993-06-03 CN CN93108420A patent/CN1101908A/zh active Pending
- 1993-06-03 PL PL29917793A patent/PL299177A1/xx unknown
- 1993-06-03 JP JP5133314A patent/JPH0680666A/ja active Pending
-
1995
- 1995-05-30 US US08/453,591 patent/US5693633A/en not_active Expired - Fee Related
- 1995-05-30 US US08/453,532 patent/US5556981A/en not_active Expired - Fee Related
- 1995-05-31 US US08/455,239 patent/US5569768A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NZ247770A (en) | 1995-10-26 |
| NO932004D0 (no) | 1993-06-02 |
| TW252109B (fi) | 1995-07-21 |
| DE69333138D1 (de) | 2003-09-18 |
| MX9303263A (es) | 1993-12-01 |
| IL105878A0 (en) | 1993-10-20 |
| FI932518A7 (fi) | 1993-12-04 |
| DE69333138T2 (de) | 2004-06-09 |
| JPH0680666A (ja) | 1994-03-22 |
| CZ104593A3 (en) | 1994-01-19 |
| US5693633A (en) | 1997-12-02 |
| NO932004L (no) | 1993-12-06 |
| EP0574174A2 (en) | 1993-12-15 |
| AU661396B2 (en) | 1995-07-20 |
| ATE247107T1 (de) | 2003-08-15 |
| EP0574174B1 (en) | 2003-08-13 |
| ES2204898T3 (es) | 2004-05-01 |
| AU3998693A (en) | 1993-12-09 |
| HUT64330A (en) | 1993-12-28 |
| US5612360A (en) | 1997-03-18 |
| CN1101908A (zh) | 1995-04-26 |
| PL299177A1 (en) | 1994-02-07 |
| EP0574174A3 (en) | 1994-07-06 |
| CA2097460A1 (en) | 1993-12-04 |
| FI932518A0 (fi) | 1993-06-02 |
| PT574174E (pt) | 2003-12-31 |
| US5569768A (en) | 1996-10-29 |
| KR940005617A (ko) | 1994-03-21 |
| HU9301602D0 (en) | 1993-09-28 |
| DK0574174T3 (da) | 2003-12-08 |
| US5556981A (en) | 1996-09-17 |
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