[go: up one dir, main page]

FI931503L - Indolderivat som antiallergiska och antiinflammatoriska aemnen - Google Patents

Indolderivat som antiallergiska och antiinflammatoriska aemnen Download PDF

Info

Publication number
FI931503L
FI931503L FI931503A FI931503A FI931503L FI 931503 L FI931503 L FI 931503L FI 931503 A FI931503 A FI 931503A FI 931503 A FI931503 A FI 931503A FI 931503 L FI931503 L FI 931503L
Authority
FI
Finland
Prior art keywords
indolderivas
aemnen
som
allergic
inflammatory
Prior art date
Application number
FI931503A
Other languages
English (en)
Other versions
FI931503A7 (fi
FI931503A0 (fi
Inventor
Rodney William Stevens
Hiromasa Morita
Masami Nakane
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI931503A7 publication Critical patent/FI931503A7/fi
Publication of FI931503L publication Critical patent/FI931503L/fi
Publication of FI931503A0 publication Critical patent/FI931503A0/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/08Bronchodilators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/08Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI931503A 1990-10-03 1991-10-01 Indolderivat som antiallergiska och antiinflammatoriska aemnen FI931503A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2265687A JPH0764841B2 (ja) 1990-10-03 1990-10-03 インドール誘導体およびその用途
PCT/US1991/007045 WO1992006088A1 (en) 1990-10-03 1991-10-01 Indole derivatives as antiallergy and antiinflammatory agents

Publications (3)

Publication Number Publication Date
FI931503A7 FI931503A7 (fi) 1993-04-02
FI931503L true FI931503L (fi) 1993-04-02
FI931503A0 FI931503A0 (fi) 1993-04-02

Family

ID=17420610

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931503A FI931503A0 (fi) 1990-10-03 1991-10-01 Indolderivat som antiallergiska och antiinflammatoriska aemnen

Country Status (13)

Country Link
US (1) US5290788A (fi)
EP (1) EP0544821B1 (fi)
JP (1) JPH0764841B2 (fi)
AT (1) ATE116983T1 (fi)
CA (1) CA2092404A1 (fi)
DE (1) DE69106715T2 (fi)
DK (1) DK0544821T3 (fi)
ES (1) ES2067248T3 (fi)
FI (1) FI931503A0 (fi)
GR (1) GR3015313T3 (fi)
IE (1) IE64451B1 (fi)
PT (1) PT99154A (fi)
WO (1) WO1992006088A1 (fi)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5290798A (en) * 1991-09-30 1994-03-01 Merck Frosst Canada, Inc. (hetero-arylmethoxy)indoles as inhibitors of leukotriene biosynthesis
US5389650A (en) * 1991-09-30 1995-02-14 Merck Frosst Canada, Inc. (Azaarylmethoxy)indoles as inhibitors of leukotriene biosynthesis
US5374635A (en) * 1993-03-29 1994-12-20 Merck Frosst Canada, Inc. Furo[3,2-b]pyridines and thieno[3,2-b]pyridines as inhibitors of leukotriene biosynthesis
US5641800A (en) * 1994-07-21 1997-06-24 Eli Lilly And Company 1H-indole-1-functional sPLA2 inhibitors
KR100303662B1 (ko) * 1998-06-10 2001-12-12 황기준 N-아세틸-5-메톡시트립타민의 제조방법
JP4292742B2 (ja) * 2000-03-09 2009-07-08 小野薬品工業株式会社 インドール誘導体、その製造方法および用途
JP2004513076A (ja) 2000-07-25 2004-04-30 メルク エンド カムパニー インコーポレーテッド 糖尿病治療で有用なn−置換インドール類
US6503907B2 (en) * 2000-11-28 2003-01-07 Hoffmann-La Roche Inc. Indole and dihydroindole derivatives
ATE530183T1 (de) * 2001-01-29 2011-11-15 Ortho Mcneil Pharm Inc Substituierte indole und ihre verwendung als integrin-antagonisten
US6872730B2 (en) * 2001-04-27 2005-03-29 3-Dimensional Pharmaceuticals, Inc. Substituted benzofurans and benzothiophenes, methods of making and methods of use as integrin antagonists
ATE445838T1 (de) 2001-07-25 2009-10-15 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
US7153852B2 (en) * 2001-09-07 2006-12-26 Ono Pharmaceutical Co., Ltd. Indole compounds, process for producing the same and drugs containing the same as the active ingredient
US6933316B2 (en) 2001-12-13 2005-08-23 National Health Research Institutes Indole compounds
US7632955B2 (en) 2001-12-13 2009-12-15 National Health Research Institutes Indole compounds
US7528165B2 (en) 2001-12-13 2009-05-05 National Health Research Institutes Indole compounds
US7456289B2 (en) 2004-12-31 2008-11-25 National Health Research Institutes Anti-tumor compounds
CA2789097C (en) 2005-04-28 2017-02-21 Proteus Digital Health, Inc. Pharma-informatics system
US20070244128A1 (en) * 2005-11-04 2007-10-18 Amira Pharmaceuticals, Inc. 5-lipoxygenase-activating protein (flap) inhibitors
US20070225285A1 (en) * 2005-11-04 2007-09-27 Amira Pharmaceuticals, Inc. 5-lipoxygenase-activating protein (flap) inhibitors
US20070219206A1 (en) * 2005-11-04 2007-09-20 Amira Pharmaceuticals, Inc. 5-lipoxygenase-activating protein (flap) inhibitors
GB2431927B (en) * 2005-11-04 2010-03-17 Amira Pharmaceuticals Inc 5-Lipoxygenase-activating protein (FLAP) inhibitors
US7977359B2 (en) * 2005-11-04 2011-07-12 Amira Pharmaceuticals, Inc. 5-lipdxygenase-activating protein (FLAP) inhibitors
US8399666B2 (en) * 2005-11-04 2013-03-19 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質(rap)結合体の投与による肝障害の処置
TW200920369A (en) * 2007-10-26 2009-05-16 Amira Pharmaceuticals Inc 5-lipoxygenase activating protein (flap) inhibitor
MX2010012814A (es) * 2008-05-23 2010-12-20 Amira Pharmaceuticals Inc Inhibidor de proteina activadora de 5-lipoxigenasa.
US8546431B2 (en) 2008-10-01 2013-10-01 Panmira Pharmaceuticals, Llc 5-lipoxygenase-activating protein (FLAP) inhibitors
NZ616673A (en) 2009-02-20 2014-08-29 To Bbb Holding B V Glutathione-based drug delivery system
ES2942923T3 (es) 2009-05-06 2023-06-07 Laboratory Skin Care Inc Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK136033B (da) * 1967-12-27 1977-08-01 Lodzkie Zaklady Farma Fremgangsmåde til fremstilling af indolyl-3-eddikesyrer.
DE2058140A1 (de) * 1970-11-26 1972-05-31 Novo Terapeutisk Labor As Indol-Derivate
JPS6084281A (ja) * 1983-09-14 1985-05-13 Yoshitomi Pharmaceut Ind Ltd 3−インド−ルカルボキサミド類
JPS6160648A (ja) * 1984-08-31 1986-03-28 Teikoku Hormone Mfg Co Ltd 2−(3,5−ジアルキル−4−ヒドロキシフエニル)インド−ル誘導体
US4758586A (en) * 1985-02-01 1988-07-19 Usv Pharmaceutical Corp. Indolyl compounds and hyposensitivity use thereof
NZ234883A (en) * 1989-08-22 1995-01-27 Merck Frosst Canada Inc Quinolin-2-ylmethoxy indole derivatives, preparation and pharmaceutical compositions thereof

Also Published As

Publication number Publication date
FI931503A7 (fi) 1993-04-02
DE69106715T2 (de) 1995-05-11
US5290788A (en) 1994-03-01
EP0544821B1 (en) 1995-01-11
IE913477A1 (en) 1992-04-08
JPH04145079A (ja) 1992-05-19
EP0544821A1 (en) 1993-06-09
IE64451B1 (en) 1995-08-09
JPH0764841B2 (ja) 1995-07-12
ATE116983T1 (de) 1995-01-15
FI931503A0 (fi) 1993-04-02
CA2092404A1 (en) 1992-04-04
GR3015313T3 (en) 1995-06-30
DE69106715D1 (de) 1995-02-23
PT99154A (pt) 1993-12-31
WO1992006088A1 (en) 1992-04-16
DK0544821T3 (da) 1995-05-01
ES2067248T3 (es) 1995-03-16

Similar Documents

Publication Publication Date Title
FI931503L (fi) Indolderivat som antiallergiska och antiinflammatoriska aemnen
FI932082L (fi) Foerbaettringar i och angaoende fodrande av roerledningar
FI924382A7 (fi) Foerfarande och anordning foer jontoforetisk avgivning av laekemedel
FI924472L (fi) Foerfarande och komposition foer behandling av trombos
FI932762L (fi) Hydrogenperoxid foerstoerande kompositioner och foerfaranden foer framstaellning av desamma
FI932451A7 (fi) Anordning foer maskintvaettning av klaeder och foerfarande foer anvaendning av naemnda anordning
FI925480L (fi) Vattenloeslig pentacyklisk triterpenkomposition och foerfarande foer framstaellning av densamma
FI923747L (fi) Kompositioner och foerfaranden foer behandling av infektioner foerorsakade av organismer sensitiva foer b-laktamantibiotika
FI924272A7 (fi) Foerfarande och anordning foer maskinbearbetning av valsar och liknande arbetsstycken
FI923756L (fi) Polyolefinkompositioner som omfattar glycerolmonoestrar av c20-24-fettsyror och daerav framstaellda skumprodukter
FI924725L (fi) Antiinflammatoriska hydroxiaminsyror och n-hydroxiureor
FI931333L (fi) Foerfarande foer framstaellning av formoterol och liknande foereningar
FI930905L (fi) Foerfarande foer uppsamling och behandling av icke-vattenhaltiga droppvaetskor
FI923814L (fi) Foerfarande foer oevervakning och reglering av primaer kaernbildning av jaernsmaeltor
FI925052L (fi) Foerfarande foer kontinuerlig framstaellning av sanitetsprodukter saosom bloejbyxor och saolunda framstaelld sanitetsprodukt
FI933136A0 (fi) Antiallergiska och antiinflammatoriska n-hydroxiureaderivat
FI872555L (fi) Antiallergiska och antiinflammatoriska aemnen.
FI925327A7 (fi) Foerfarande foer vaord av inflammation och i dessa anvaendbara foereningar och kompositioner
FI882538A7 (fi) Antiallergiska och antiinflammatoriska dihydropyridiner.
FI930860L (fi) Tropolonderivat och farmaceutiska kompositioner saerav foer avvaerjning och behandling av iskemiska sjukdomar
FI924713L (fi) Foerfarande foer saollning av proteinpartner och anvaendning av dessa
FI925692A7 (fi) Foerfarande och anordning foer testning och oevervakning av majoritetsroestning
FI971376A0 (fi) Trofinin och trofininmedlande proteiner
FI925453L (fi) Lipasderivat stimulerade av maenniskans gallsalter och farmaceutiska aemnen innehaollande daerav
FI933376A0 (fi) 4-amino-3-acylkinolinderivater och deras anvaendning som inhibitorer avmagsyrasekretion

Legal Events

Date Code Title Description
FD Application lapsed