FI931333L - Foerfarande foer framstaellning av formoterol och liknande foereningar - Google Patents

Foerfarande foer framstaellning av formoterol och liknande foereningar Download PDF

Info

Publication number: FI931333L
Authority: FI; Finland
Prior art keywords: foereningar; formoterol; foerfarande foer; foer framstaellning; och liknande
Prior art date: 1990-09-26

Application number

FI931333A

Other languages

English (en)

Other versions

FI111714B (fi

FI931333A0 (fi

Inventor

Jan William Trofast

Edib Jakupovic

Lena Katarina Maonsson

Original Assignee

Astra Ab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-09-26

Filing date

1993-03-25

Publication date

1993-04-22

1993-03-25 Application filed by Astra Ab filed Critical Astra Ab

1993-03-25 Publication of FI931333A0 publication Critical patent/FI931333A0/fi

1993-04-22 Publication of FI931333L publication Critical patent/FI931333L/fi

2003-09-15 Application granted granted Critical

2003-09-15 Publication of FI111714B publication Critical patent/FI111714B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/34—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups
- C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/14—Preparation of carboxylic acid amides by formation of carboxamide groups together with reactions not involving the carboxamide groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Saccharide Compounds (AREA)
Pyrrole Compounds (AREA)
Steroid Compounds (AREA)

FI931333A 1990-09-26 1993-03-25 Uusi menetelmä formoterolin ja lähisukuisten yhdisteiden valmistamiseksi FI111714B (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
SE9003057A SE9003057D0 (sv)	1990-09-26	1990-09-26	New process
SE9003057		1990-09-26
PCT/SE1991/000643 WO1992005147A1 (en)	1990-09-26	1991-09-25	New process for preparing formoterol and related compounds
SE9100643		1991-09-25

Publications (3)

Publication Number	Publication Date
FI931333A0 FI931333A0 (fi)	1993-03-25
FI931333L true FI931333L (fi)	1993-04-22
FI111714B FI111714B (fi)	2003-09-15

Family

ID=20380456

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI931333A FI111714B (fi)	1990-09-26	1993-03-25	Uusi menetelmä formoterolin ja lähisukuisten yhdisteiden valmistamiseksi

Country Status (28)

Country	Link
EP (1)	EP0550612B1 (fi)
JP (1)	JP2801401B2 (fi)
KR (1)	KR0179639B1 (fi)
AT (1)	ATE134990T1 (fi)
AU (1)	AU652386B2 (fi)
BG (1)	BG61605B1 (fi)
CA (1)	CA2091343C (fi)
CZ (1)	CZ284256B6 (fi)
DE (1)	DE69117768T2 (fi)
DK (1)	DK0550612T3 (fi)
EE (1)	EE02979B1 (fi)
ES (1)	ES2084831T3 (fi)
FI (1)	FI111714B (fi)
GR (1)	GR3020134T3 (fi)
HK (1)	HK52297A (fi)
HU (1)	HU214054B (fi)
IE (1)	IE74387B1 (fi)
IS (1)	IS1684B (fi)
LT (1)	LT3813B (fi)
LV (1)	LV10770B (fi)
NO (1)	NO301709B1 (fi)
PL (1)	PL166434B1 (fi)
PT (1)	PT99051B (fi)
RU (1)	RU2079486C1 (fi)
SE (1)	SE9003057D0 (fi)
SG (1)	SG43150A1 (fi)
SK (1)	SK22793A3 (fi)
WO (1)	WO1992005147A1 (fi)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6866839B2 (en)	1991-04-05	2005-03-15	Sepracor Inc.	Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
US6299863B1 (en)	1992-04-03	2001-10-09	Sepracor Inc.	Aerosol formulations containing micronized optically pure (R,R) formoterol for bronchodilating therapy
US5795564A (en) *	1991-04-05	1998-08-18	Sepracor, Inc.	Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol
US5629200A (en) *	1993-11-18	1997-05-13	Daicel Chemical Industries, Ltd.	Production of optically active 2-amino-1-phenylethanol derivatives by asymetrical assimilation
SE9404080L (sv) *	1993-12-28	1995-06-29	Ciba Geigy Ag	Förfarande för framställning av en optiskt ren enantiomer av formoterol
US6040344A (en) *	1996-11-11	2000-03-21	Sepracor Inc.	Formoterol process
JP2001503772A (ja) *	1996-11-11	2001-03-21	セプラクール，インコーポレイテッド	フォルモテロールの光学的に純粋な異性体の製造方法
US6303145B2 (en)	1999-05-10	2001-10-16	Sepracor Inc.	(S,R) formoterol methods and compositions
AR028948A1 (es)	2000-06-20	2003-05-28	Astrazeneca Ab	Compuestos novedosos
DE10290562D2 (de) *	2001-02-22	2004-04-29	Universitaetsklinikum Charite	Zielkomplex als Mittel zur Hemmung von Tumorzellen und zur Stimulierung der Angiogenese
US6472563B1 (en)	2001-11-09	2002-10-29	Sepracor Inc.	Formoterol tartrate process and polymorph
TWI359675B (en)	2003-07-10	2012-03-11	Dey L P	Bronchodilating β-agonist compositions
TW200738634A (en)	2005-08-02	2007-10-16	Astrazeneca Ab	New salt
WO2008035380A2 (en) *	2006-09-19	2008-03-27	Natco Pharma Limited	An improved process for the preparation of high purity formoterol and its pharmaceutically acceptable salts
TW200825084A (en)	2006-11-14	2008-06-16	Astrazeneca Ab	New compounds 521
CA2703762A1 (en) *	2007-10-29	2009-05-07	Generics [Uk] Limited	Novel chromatography methods
BRPI0822693A2 (pt)	2008-05-13	2015-07-07	Astrazeneca Ab	Derivados de quinuclidina como antagonistas do receptor muscarínico m3
CN101921200B (zh) *	2009-06-16	2014-01-15	上海医药工业研究院	一种n-苄基-1-(4-甲氧基苯基)-2-丙胺的制备方法
WO2011061527A1 (en)	2009-11-17	2011-05-26	Astrazeneca Ab	Combinations comprising a glucocorticoid receptor modulator for the treatment of respiratory diseases
CN115368250B (zh) *	2022-09-02	2024-07-26	博诺康源(北京)药业科技有限公司	拆分福莫特罗手性中间体的方法
CN117682969A (zh) *	2023-07-31	2024-03-12	浙江理工大学	一种福莫特罗中间体的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE2305092A1 (de)	1972-02-05	1973-08-16	Yamanouchi Pharma Co Ltd	Alpha-aminomethylbenzylalkoholderivate
GB1468156A (en) *	1973-07-19	1977-03-23	Ici Ltd	Phenylethylamine derivatives
JPS643121A (en)	1987-06-25	1989-01-06	Mitsubishi Kasei Corp	Remedy for endometriosis
ES2005492A6 (es)	1987-12-23	1989-03-01	Lasa Lab	Procedimiento de obtencion de n-(2-hidroxi-5-(1-hidroxi-2((2- (4-metoxifenil)-1metiletil)amino)etil)fenil)foramida (i).

1990
- 1990-09-26 SE SE9003057A patent/SE9003057D0/xx unknown
1991
- 1991-09-25 AT AT91917624T patent/ATE134990T1/de not_active IP Right Cessation
- 1991-09-25 KR KR1019930700901A patent/KR0179639B1/ko not_active Expired - Lifetime
- 1991-09-25 DE DE69117768T patent/DE69117768T2/de not_active Expired - Lifetime
- 1991-09-25 DK DK91917624.8T patent/DK0550612T3/da active
- 1991-09-25 RU RU9193005269A patent/RU2079486C1/ru active
- 1991-09-25 HU HU9300867A patent/HU214054B/hu unknown
- 1991-09-25 JP JP3516242A patent/JP2801401B2/ja not_active Expired - Lifetime
- 1991-09-25 SK SK22793A patent/SK22793A3/sk unknown
- 1991-09-25 SG SG1996004479A patent/SG43150A1/en unknown
- 1991-09-25 PL PL91298237A patent/PL166434B1/pl unknown
- 1991-09-25 CZ CZ93442A patent/CZ284256B6/cs not_active IP Right Cessation
- 1991-09-25 WO PCT/SE1991/000643 patent/WO1992005147A1/en not_active Ceased
- 1991-09-25 ES ES91917624T patent/ES2084831T3/es not_active Expired - Lifetime
- 1991-09-25 CA CA002091343A patent/CA2091343C/en not_active Expired - Lifetime
- 1991-09-25 AU AU86520/91A patent/AU652386B2/en not_active Expired
- 1991-09-25 PT PT99051A patent/PT99051B/pt not_active IP Right Cessation
- 1991-09-25 IS IS3756A patent/IS1684B/is unknown
- 1991-09-25 EP EP91917624A patent/EP0550612B1/en not_active Expired - Lifetime
- 1991-09-26 IE IE337391A patent/IE74387B1/en not_active IP Right Cessation
1993
- 1993-03-23 NO NO931058A patent/NO301709B1/no not_active IP Right Cessation
- 1993-03-24 BG BG97576A patent/BG61605B1/bg unknown
- 1993-03-25 FI FI931333A patent/FI111714B/fi not_active IP Right Cessation
- 1993-08-10 LV LVP-93-1025A patent/LV10770B/en unknown
- 1993-12-30 LT LTIP1715A patent/LT3813B/lt not_active IP Right Cessation
1994
- 1994-11-23 EE EE9400425A patent/EE02979B1/xx unknown
1996
- 1996-05-31 GR GR960401514T patent/GR3020134T3/el unknown
1997
- 1997-04-24 HK HK52297A patent/HK52297A/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
HU214054B (en)	1997-12-29
JPH06501262A (ja)	1994-02-10
KR0179639B1 (ko)	1999-05-15
IS3756A7 (is)	1992-03-27
GR3020134T3 (en)	1996-08-31
FI111714B (fi)	2003-09-15
BG61605B1 (bg)	1998-01-30
CZ284256B6 (cs)	1998-10-14
NO931058L (no)	1993-03-23
HU9300867D0 (en)	1993-06-28
SK22793A3 (en)	1993-07-07
HUT65912A (en)	1994-07-28
FI931333A0 (fi)	1993-03-25
LV10770B (en)	1996-04-20
SE9003057D0 (sv)	1990-09-26
JP2801401B2 (ja)	1998-09-21
CZ44293A3 (en)	1994-01-19
ES2084831T3 (es)	1996-05-16
IS1684B (is)	1998-02-24
ATE134990T1 (de)	1996-03-15
SG43150A1 (en)	1997-10-17
IE913373A1 (en)	1992-04-08
LT3813B (en)	1996-03-25
PT99051B (pt)	1999-02-26
EP0550612A1 (en)	1993-07-14
EP0550612B1 (en)	1996-03-06
IE74387B1 (en)	1997-07-30
AU8652091A (en)	1992-04-15
CA2091343A1 (en)	1992-03-27
LTIP1715A (en)	1995-07-25
DE69117768T2 (de)	1996-08-29
AU652386B2 (en)	1994-08-25
DK0550612T3 (da)	1996-07-22
DE69117768D1 (de)	1996-04-11
WO1992005147A1 (en)	1992-04-02
RU2079486C1 (ru)	1997-05-20
HK52297A (en)	1997-05-02
CA2091343C (en)	2002-07-09
EE02979B1 (et)	1997-04-15
NO301709B1 (no)	1997-12-01
LV10770A (lv)	1995-08-20
PT99051A (pt)	1992-08-31
PL166434B1 (pl)	1995-05-31
BG97576A (bg)	1994-03-31
NO931058D0 (no)	1993-03-23

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Legal Events

Date	Code	Title	Description
2011-11-25	MA	Patent expired