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FI930984L - Specifika bindningsaemne - Google Patents

Specifika bindningsaemne Download PDF

Info

Publication number
FI930984L
FI930984L FI930984A FI930984A FI930984L FI 930984 L FI930984 L FI 930984L FI 930984 A FI930984 A FI 930984A FI 930984 A FI930984 A FI 930984A FI 930984 L FI930984 L FI 930984L
Authority
FI
Finland
Prior art keywords
specific binding
binding subject
subject
specific
binding
Prior art date
Application number
FI930984A
Other languages
English (en)
Other versions
FI113873B (fi
FI930984A0 (fi
Inventor
Martine Elisa Verhoeyen
Original Assignee
Unilever Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Unilever Nv filed Critical Unilever Nv
Publication of FI930984L publication Critical patent/FI930984L/fi
Publication of FI930984A0 publication Critical patent/FI930984A0/fi
Application granted granted Critical
Publication of FI113873B publication Critical patent/FI113873B/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • C07K16/464—Igs containing CDR-residues from one specie grafted between FR-residues from another
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pretreatment Of Seeds And Plants (AREA)
  • Nonmetallic Welding Materials (AREA)
FI930984A 1990-09-07 1993-03-05 Menetelmä valmistaa muotoiltua ihmisen vasta-ainetta tai muotoiltua ihmisen vasta-ainefragmenttia, DNA-sekvenssejä, plasmidi ja pysyvä isäntäsolulinja FI113873B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB9019553 1990-09-07
GB909019553A GB9019553D0 (en) 1990-09-07 1990-09-07 Specific binding agents
GB9101511 1991-09-05
PCT/GB1991/001511 WO1992004380A1 (en) 1990-09-07 1991-09-05 Specific binding agents

Publications (3)

Publication Number Publication Date
FI930984L true FI930984L (fi) 1993-03-05
FI930984A0 FI930984A0 (fi) 1993-03-05
FI113873B FI113873B (fi) 2004-06-30

Family

ID=10681827

Family Applications (2)

Application Number Title Priority Date Filing Date
FI930984A FI113873B (fi) 1990-09-07 1993-03-05 Menetelmä valmistaa muotoiltua ihmisen vasta-ainetta tai muotoiltua ihmisen vasta-ainefragmenttia, DNA-sekvenssejä, plasmidi ja pysyvä isäntäsolulinja
FI20011739A FI114611B (fi) 1990-09-07 2001-08-31 Muotoiltu ihmisen vasta-aine tai muotoiltu ihmisen vasta-ainefragmentti

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI20011739A FI114611B (fi) 1990-09-07 2001-08-31 Muotoiltu ihmisen vasta-aine tai muotoiltu ihmisen vasta-ainefragmentti

Country Status (18)

Country Link
US (2) US6204366B1 (fi)
EP (1) EP0483961B1 (fi)
JP (2) JP3514456B2 (fi)
KR (1) KR930702526A (fi)
AT (1) ATE233279T1 (fi)
AU (1) AU653167B2 (fi)
BG (1) BG60716B1 (fi)
CA (1) CA2090961C (fi)
DE (1) DE69133200T2 (fi)
DK (1) DK0483961T3 (fi)
ES (1) ES2193129T3 (fi)
FI (2) FI113873B (fi)
GB (1) GB9019553D0 (fi)
HU (2) HU9300609D0 (fi)
NO (2) NO314595B1 (fi)
RO (1) RO113432B1 (fi)
UA (1) UA46691C2 (fi)
WO (1) WO1992004380A1 (fi)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4124480B2 (ja) 1991-06-14 2008-07-23 ジェネンテック・インコーポレーテッド 免疫グロブリン変異体
US6800738B1 (en) 1991-06-14 2004-10-05 Genentech, Inc. Method for making humanized antibodies
WO1994004679A1 (en) * 1991-06-14 1994-03-03 Genentech, Inc. Method for making humanized antibodies
US5869619A (en) * 1991-12-13 1999-02-09 Xoma Corporation Modified antibody variable domains
CA2507749C (en) * 1991-12-13 2010-08-24 Xoma Corporation Methods and materials for preparation of modified antibody variable domains and therapeutic uses thereof
WO1994011508A2 (en) * 1992-11-13 1994-05-26 Cancer Research Fund Of Contra Costa Polypeptides with specificity for neoplasias, kit, and diagnostic, vaccination, and therapeutic methods
US5804187A (en) 1992-11-16 1998-09-08 Cancer Research Fund Of Contra Costa Modified antibodies with human milk fat globule specificity
US6281335B1 (en) * 1993-10-08 2001-08-28 Coulter Corporation Hybridoma and anti-KC-4 humanized monoclonal antibody
DE69332930T2 (de) * 1992-11-16 2004-02-26 Cancer Research Fund Of Contra Costa, Walnut Creek Peptide mit breiter neoplastischer spezifizität
US5792852A (en) * 1992-11-16 1998-08-11 Cancer Research Fund Of Contra Costa Polynucleotides encoding modified antibodies with human milk fat globule specificity
JPH07203974A (ja) * 1994-01-13 1995-08-08 Tosoh Corp 癌特異的ムチンを認識する抗体の遺伝子断片等
EP0781847A1 (en) * 1995-11-06 1997-07-02 MERCK PATENT GmbH Humanized monoclonal antibody
CN1294517A (zh) * 1997-11-14 2001-05-09 欧洲细胞技术有限公司 具有合成可变区和修饰特异性的免疫球蛋白分子
GB2360771A (en) * 2000-03-28 2001-10-03 Antisoma Res Ltd Compounds for targeting
WO2001074905A1 (en) * 2000-04-03 2001-10-11 Antisoma Research Limited Compounds for targeting
WO2002078613A2 (en) * 2001-04-02 2002-10-10 Purdue Pharma L.P. Immunoglobulin construct containing anti-mucin variable domain sequences for eliciting an anti-idiotype anti-tumor response
GB0200657D0 (en) * 2002-01-12 2002-02-27 Antisoma Plc Cancer treatment
CA2488441C (en) * 2002-06-03 2015-01-27 Genentech, Inc. Synthetic antibody phage libraries
AU2003256566A1 (en) * 2002-07-16 2004-02-02 Stuart Bussell Methods to construct multimeric dna and polymeric protein sequences as direct fusions or with linkers
KR20060069825A (ko) * 2003-08-01 2006-06-22 제넨테크, 인크. 제한된 다양성을 갖는 항체 ｃｄｒ 폴리펩티드 서열
GB0519398D0 (en) * 2005-09-23 2005-11-02 Antisoma Plc Biological materials and uses thereof
EP1957531B1 (en) 2005-11-07 2016-04-13 Genentech, Inc. Binding polypeptides with diversified and consensus vh/vl hypervariable sequences
US20070237764A1 (en) * 2005-12-02 2007-10-11 Genentech, Inc. Binding polypeptides with restricted diversity sequences
CA2814652C (en) 2010-10-13 2021-05-18 Janssen Biotech, Inc. Human oncostatin m antibodies and methods of use
US20140079722A1 (en) * 2011-03-09 2014-03-20 Centrose, Llc Extracellular targeted drug conjugates
RU2493165C1 (ru) * 2012-02-28 2013-09-20 Общество с ограниченной ответственностью "Технофарма" Наноантитело, специфически связывающее белок muc1, способ детекции белка muc1 с помощью наноантител
RU2018102251A (ru) 2012-04-30 2019-02-21 Байотера, Инк. СПОСОБЫ β-ГЛЮКАНОВОЙ ИММУНОТЕРАПИИ

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607679D0 (en) * 1986-03-27 1986-04-30 Winter G P Recombinant dna product
EP0341252B1 (en) * 1987-01-07 1997-11-19 Imperial Cancer Research Technology Limited Human polymorphic epithelial mucin polypeptides for use in therapy and diagnosis
DE3853515T3 (de) * 1987-05-21 2005-08-25 Micromet Ag Multifunktionelle proteine mit vorbestimmter zielsetzung.
JPH03503120A (ja) * 1988-02-08 1991-07-18 ジョン　ミュア　キャンサー　アンド　エージング　インスティチュート　ディビジョン　オブ　ジョン　ミュア　メモリアル　ホスピタル ヒトのガン細胞における新規なムチン様糖蛋白質表面抗原に特異的なモノクローナル抗体
JPH04501719A (ja) * 1988-11-10 1992-03-26 インペリアル・キヤンサー・リサーチ・テクノロジー・リミテツド ポリペプチド
JPH02273195A (ja) * 1988-11-17 1990-11-07 Univ Melbourne ヒト多型性上皮ムチンと反応するモノクローナル抗体
US5075219A (en) * 1989-04-05 1991-12-24 John Muir Cancer & Aging Institute Monoclonal antibody which recognizes a specific glycoprotein of a human milk-fat globule membrane mucin antigen and said mucin antigen
WO1991007500A1 (en) * 1989-11-17 1991-05-30 Unilever Plc Specific binding agents

Also Published As

Publication number Publication date
AU653167B2 (en) 1994-09-22
FI114611B (fi) 2004-11-30
JP3514456B2 (ja) 2004-03-31
NO930825D0 (no) 1993-03-05
KR930702526A (ko) 1993-09-09
US6204366B1 (en) 2001-03-20
DE69133200D1 (de) 2003-04-03
DK0483961T3 (da) 2003-06-23
ES2193129T3 (es) 2003-11-01
FI113873B (fi) 2004-06-30
JPH06500468A (ja) 1994-01-20
GB9019553D0 (en) 1990-10-24
WO1992004380A1 (en) 1992-03-19
NO315239B1 (no) 2003-08-04
DE69133200T2 (de) 2003-11-20
NO930825L (no) 1993-05-05
RO113432B1 (ro) 1998-07-30
CA2090961A1 (en) 1992-03-08
HU9300609D0 (en) 1993-05-28
ATE233279T1 (de) 2003-03-15
BG97607A (bg) 1994-03-31
JP2003061689A (ja) 2003-03-04
CA2090961C (en) 2004-01-20
NO314595B1 (no) 2003-04-14
NO20014822D0 (no) 2001-10-04
AU8495391A (en) 1992-03-30
FI930984A0 (fi) 1993-03-05
NO20014822L (no) 1993-05-05
HUT67796A (en) 1995-04-28
UA46691C2 (uk) 2002-06-17
EP0483961A1 (en) 1992-05-06
BG60716B1 (en) 1996-01-31
US20020086978A1 (en) 2002-07-04
EP0483961B1 (en) 2003-02-26

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MA Patent expired