FI920036A0 - 6-(hydroxinaftyl-1-etyl)-4-hydroxi -3,4,5,6-tetrahydro-2h-pyran-2-oner och motsvarande hydroxisyror. - Google Patents

6-(hydroxinaftyl-1-etyl)-4-hydroxi -3,4,5,6-tetrahydro-2h-pyran-2-oner och motsvarande hydroxisyror.

Info

Publication number: FI920036A0
Authority: FI; Finland
Prior art keywords: hydroxisyror; hydroxinaftyl; oner; pyran; tetrahydro
Prior art date: 1989-07-04

Application number

FI920036A

Other languages

English (en)

Other versions

FI920036A7 (fi

Inventor

Christopher Norman Lewis

Alan Hornsby Davidson

Christopher David Floyd

Jonathan Philip Dickens

Original Assignee

British Bio Technology

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-07-04

Filing date

1990-07-04

Publication date

1992-01-03

1990-07-04 Application filed by British Bio Technology filed Critical British Bio Technology

1992-01-03 Publication of FI920036A0 publication Critical patent/FI920036A0/fi

1992-01-03 Publication of FI920036A7 publication Critical patent/FI920036A7/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/732—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/66—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
- C07C69/73—Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
- C07C69/738—Esters of keto-carboxylic acids or aldehydo-carboxylic acids
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/16—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D309/28—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/30—Oxygen atoms, e.g. delta-lactones

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Cardiology (AREA)
Urology & Nephrology (AREA)
Diabetes (AREA)
Hematology (AREA)
Obesity (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Pyrane Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Medicinal Preparation (AREA)

FI920036A 1989-07-04 1990-07-04 6-(hydroksinaftyyli-1-etyyli)-4-hydroksi-3,4,5,6-tetrahydro-2H-pyran-2 -onit ja vastaavat hydroksihapot FI920036A7 (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB898915280A GB8915280D0 (en)	1989-07-04	1989-07-04	Compounds
PCT/GB1990/001030 WO1991000280A1 (en)	1989-07-04	1990-07-04	6-(hydronaphtyl-1-ethyl)-4-hydroxy-3,4,5,6-tetrahydro-2h-pyran-2-ones and the corresponding hydroxy acids

Publications (2)

Publication Number	Publication Date
FI920036A0 true FI920036A0 (fi)	1992-01-03
FI920036A7 FI920036A7 (fi)	1992-01-03

Family

ID=10659493

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI920036A FI920036A7 (fi)	1989-07-04	1990-07-04	6-(hydroksinaftyyli-1-etyyli)-4-hydroksi-3,4,5,6-tetrahydro-2H-pyran-2 -onit ja vastaavat hydroksihapot

Country Status (14)

Country	Link
US (1)	US5308864A (fi)
EP (1)	EP0480986A1 (fi)
JP (1)	JPH04506523A (fi)
KR (1)	KR920703563A (fi)
AU (1)	AU631909B2 (fi)
CA (1)	CA2060212A1 (fi)
FI (1)	FI920036A7 (fi)
GB (1)	GB8915280D0 (fi)
HU (1)	HUT62254A (fi)
IE (1)	IE902417A1 (fi)
NO (1)	NO920057L (fi)
NZ (1)	NZ234369A (fi)
PT (1)	PT94584A (fi)
WO (1)	WO1991000280A1 (fi)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9111192D0 (en) *	1991-05-23	1991-07-17	British Bio Technology	Synthetic process
GB9115773D0 (en) *	1991-07-22	1991-09-04	British Bio Technology	Synthetic process
GB9126144D0 (en) *	1991-12-10	1992-02-12	British Bio Technology	Compounds
GB9208790D0 (en) *	1992-04-23	1992-06-10	British Bio Technology	Compounds
NZ250609A (en) *	1992-12-28	1995-07-26	Sankyo Co	Hexahydronaphthalene esters and ring closed lactones; preparation and medicaments
WO1997031628A1 (en) *	1996-02-28	1997-09-04	Innapharma, Inc.	Peptidomimetics for the treatment of hiv infection
US5925672A (en) *	1996-12-06	1999-07-20	Neurosciences Research Foundation, Inc.	Methods of treating mental diseases, inflammation and pain
AU1683000A (en) *	1998-12-10	2000-06-26	Kaneka Corporation	Process for producing simvastatin
US20050113445A1 (en) *	2003-02-20	2005-05-26	Daniele Piomelli	Methods of treating mental diseases, inflammation and pain

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4293496A (en) *	1980-02-04	1981-10-06	Merck & Co., Inc.	6(R)-[2-(8-Hydroxy-2,6-dimethylpolyhydronaphthyl-1)-ethyl]-4(R)-hydroxy-3,4,5,6-tetrahydro-2H-pyran-2-ones
AU548996B2 (en) *	1980-02-04	1986-01-09	Merck & Co., Inc.	Tetrahydro-2h-pyran-2-one derivatives
US4444784A (en) *	1980-08-05	1984-04-24	Merck & Co., Inc.	Antihypercholesterolemic compounds
CA1327360C (en) *	1983-11-14	1994-03-01	William F. Hoffman	Oxo-analogs of mevinolin-like antihypercholesterolemic agents
US4668699A (en) *	1985-08-05	1987-05-26	Merck & Co., Inc.	Novel HMG-CoA reductase inhibitors
US4771071A (en) *	1986-05-05	1988-09-13	Merck & Co., Inc.	Antihypercholesterolemic compounds
US4661483A (en) *	1986-05-05	1987-04-28	Merck & Co., Inc.	Antihypercholesterolemic lactone compounds, compositions and use
PT85109A (en) *	1986-06-23	1987-07-01	Merck & Co Inc	Process for the preparation of hydroxy-tetrahydropyranone derivatives or corresponding ring opened dihydroxy acids which are hmg-coa reductase inhibitors

1989
- 1989-07-04 GB GB898915280A patent/GB8915280D0/en active Pending
1990
- 1990-07-04 HU HU9222A patent/HUT62254A/hu unknown
- 1990-07-04 AU AU60322/90A patent/AU631909B2/en not_active Ceased
- 1990-07-04 JP JP2510204A patent/JPH04506523A/ja active Pending
- 1990-07-04 KR KR1019920700007A patent/KR920703563A/ko not_active Withdrawn
- 1990-07-04 IE IE241790A patent/IE902417A1/en unknown
- 1990-07-04 FI FI920036A patent/FI920036A7/fi not_active Application Discontinuation
- 1990-07-04 CA CA002060212A patent/CA2060212A1/en not_active Abandoned
- 1990-07-04 NZ NZ234369A patent/NZ234369A/xx unknown
- 1990-07-04 EP EP90910793A patent/EP0480986A1/en not_active Withdrawn
- 1990-07-04 US US07/773,657 patent/US5308864A/en not_active Expired - Fee Related
- 1990-07-04 WO PCT/GB1990/001030 patent/WO1991000280A1/en not_active Ceased
- 1990-07-04 PT PT94584A patent/PT94584A/pt not_active Application Discontinuation
1992
- 1992-01-03 NO NO92920057A patent/NO920057L/no unknown

Also Published As

Publication number	Publication date
US5308864A (en)	1994-05-03
KR920703563A (ko)	1992-12-18
WO1991000280A1 (en)	1991-01-10
NO920057L (no)	1992-03-03
NZ234369A (en)	1991-10-25
CA2060212A1 (en)	1991-01-05
HUT62254A (en)	1993-04-28
NO920057D0 (no)	1992-01-03
EP0480986A1 (en)	1992-04-22
AU631909B2 (en)	1992-12-10
HU9200022D0 (en)	1992-07-28
PT94584A (pt)	1991-04-18
IE902417A1 (en)	1991-06-19
FI920036A7 (fi)	1992-01-03
GB8915280D0 (en)	1989-08-23
JPH04506523A (ja)	1992-11-12
AU6032290A (en)	1991-01-17

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Legal Events

Date	Code	Title	Description
1995-01-31	FD	Application lapsed