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FI915826L - Farmaceutiska aemnen. - Google Patents

Farmaceutiska aemnen. Download PDF

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Publication number
FI915826L
FI915826L FI915826A FI915826A FI915826L FI 915826 L FI915826 L FI 915826L FI 915826 A FI915826 A FI 915826A FI 915826 A FI915826 A FI 915826A FI 915826 L FI915826 L FI 915826L
Authority
FI
Finland
Prior art keywords
aemnen
pharmaceutical
pharmaceutical aemnen
Prior art date
Application number
FI915826A
Other languages
English (en)
Other versions
FI101193B1 (fi
FI915826A0 (fi
FI101193B (fi
Inventor
James Joseph Holohan
Ieuan John Edwards
Robert Joseph Timko
Randy John Bradway
Arlene Clements
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26298105&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI915826(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from GB909027014A external-priority patent/GB9027014D0/en
Priority claimed from GB919115107A external-priority patent/GB9115107D0/en
Application filed by Ici Plc filed Critical Ici Plc
Priority to FI980376A priority Critical patent/FI980376A0/fi
Publication of FI915826A0 publication Critical patent/FI915826A0/fi
Publication of FI915826L publication Critical patent/FI915826L/fi
Priority to FI972528A priority patent/FI106021B/fi
Application granted granted Critical
Publication of FI101193B1 publication Critical patent/FI101193B1/fi
Publication of FI101193B publication Critical patent/FI101193B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/30Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/40Nitrogen atoms, not forming part of a nitro radical, e.g. isatin semicarbazone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2027Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • A61P11/06Antiasthmatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Inorganic Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI915826A 1990-12-12 1991-12-11 Menetelmä N-£4-£5-(syklopentyylioksikarbonyyli)amino-1-metyyli-indol-3 -yyli-metyyli|-3-metoksibentsoyyli|-2-metyylibentseenisulfonamidin fys ikaalista muotoa sisältävän farmaseuttisen koostumuksen valmistamiseks i FI101193B (fi)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI980376A FI980376A0 (fi) 1990-12-12 1991-12-11 N-/4-/5-(syklopentyylioksikarbonyyli)amino-1-metyyli-indol-3-yylimetyyli/-3-metoksibentsoyyli/-2-metyylibentseenisulfonamidin fysikaalista muotoa sisältävä farmaseuttinen koostumus
FI972528A FI106021B (fi) 1990-12-12 1997-06-13 Menetelmä N-[4-[5-(syklopentyylioksikarbonyyli)amino-1-metyyli-indol-3-yyli-metyyli]-3-metoksibentsoyyli]-2-metyylibentseenisulfonamidin fysikaalisen muodon valmistamiseksi

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB909027014A GB9027014D0 (en) 1990-12-12 1990-12-12 Pharmaceutical agents
GB919115107A GB9115107D0 (en) 1991-07-12 1991-07-12 Pharmaceutical agents

Publications (4)

Publication Number Publication Date
FI915826A0 FI915826A0 (fi) 1991-12-11
FI915826L true FI915826L (fi) 1992-03-31
FI101193B1 FI101193B1 (fi) 1998-05-15
FI101193B FI101193B (fi) 1998-05-15

Family

ID=26298105

Family Applications (1)

Application Number Title Priority Date Filing Date
FI915826A FI101193B (fi) 1990-12-12 1991-12-11 Menetelmä N-£4-£5-(syklopentyylioksikarbonyyli)amino-1-metyyli-indol-3 -yyli-metyyli|-3-metoksibentsoyyli|-2-metyylibentseenisulfonamidin fys ikaalista muotoa sisältävän farmaseuttisen koostumuksen valmistamiseks i

Country Status (30)

Country Link
US (6) US5319097A (fi)
EP (1) EP0490648B1 (fi)
JP (1) JP2585495B2 (fi)
KR (2) KR0183027B1 (fi)
CN (2) CN1043405C (fi)
AP (1) AP285A (fi)
AT (1) ATE131048T1 (fi)
AU (1) AU656157B2 (fi)
BE (1) BE1004229A5 (fi)
CA (2) CA2056066C (fi)
CZ (1) CZ283181B6 (fi)
DE (2) DE69115229T2 (fi)
DK (1) DK0490648T3 (fi)
ES (1) ES2079589T3 (fi)
FI (1) FI101193B (fi)
FR (1) FR2670488B1 (fi)
GB (2) GB2251791B (fi)
GR (1) GR3018318T3 (fi)
HK (2) HK81397A (fi)
HU (2) HU213211B (fi)
IE (1) IE75348B1 (fi)
IL (1) IL100091A (fi)
IT (1) IT1256282B (fi)
MX (1) MX9102473A (fi)
MY (1) MY106315A (fi)
NZ (1) NZ240939A (fi)
PH (1) PH30928A (fi)
RU (1) RU2106140C1 (fi)
SK (2) SK279813B6 (fi)
TW (1) TW276181B (fi)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL100091A (en) * 1990-12-12 1998-08-16 Zeneca Ltd Pharmaceutical compositions containing a physical form of n-[4-[5-(cyclopentyloxycarbonyl)amino-1-methyl indol-3-yl-methyl]-2-methylbenzenesulpho-namide and process for their preparation
GB9119001D0 (en) * 1991-09-05 1991-10-23 Ici Plc Pharmaceutical agents
GR1001368B (el) * 1992-10-08 1993-10-29 Ici Plc Φαρμακευτικοί φορείς.
DE4235133A1 (de) * 1992-10-19 1994-04-21 Bayer Ag Kristallines (R)-(-)-2-Cycloheptyl-N-methylsulfonyl-[4-(2-chinolinyl-methoxy)-phenyl]-acetamid
DE9410461U1 (de) * 1994-07-01 1994-09-22 Merck Patent Gmbh, 64293 Darmstadt Mittel für die Röntgenfluoreszenzanalyse
US6279736B1 (en) 1995-04-19 2001-08-28 Capitol Specialty Plastics, Inc. Barrier pack having an absorbing agent applied to the interior of the pack
IN182496B (fi) * 1996-02-20 1999-04-17 Reddy Research Foundation
US6630496B1 (en) 1996-08-26 2003-10-07 Genetics Institute Llc Inhibitors of phospholipase enzymes
USRE43932E1 (en) 1997-07-18 2013-01-15 Novartis Ag Crystal modification of a N-phenyl-2-pyrimidineamine derivative, processes for its manufacture and its use
GB9723985D0 (en) * 1997-11-14 1998-01-14 Zeneca Ltd Pharmaceutical compositions
GB9726735D0 (en) * 1997-12-18 1998-02-18 Zeneca Ltd Pharmaceutical compositions
US6916841B2 (en) * 1998-02-25 2005-07-12 Genetics Institute, Llc Inhibitors of phospholipase enzymes
US6828344B1 (en) 1998-02-25 2004-12-07 Genetics Institute, Llc Inhibitors of phospholipase enzymes
US6500853B1 (en) 1998-02-28 2002-12-31 Genetics Institute, Llc Inhibitors of phospholipase enzymes
US6224907B1 (en) * 1998-03-06 2001-05-01 Alza Corporation Anti-asthma therapy
KR100283682B1 (ko) * 1998-07-14 2001-03-02 조정래 열풍건조장치
US6253463B1 (en) 1999-04-26 2001-07-03 Niro A/S Method of spray drying
IN191496B (fi) 1999-07-30 2003-12-06 Ranbaxy Lab Ltd
EP1216058A2 (en) * 1999-09-20 2002-06-26 Alza Corporation Process for lessening polymorphic conversion of a drug
DE10006139A1 (de) * 2000-02-11 2001-08-16 Merck Patent Gmbh Indol-3-yl-Derivate
IL139243A0 (en) * 2000-10-24 2001-11-25 Internat Specialty Products Is Ethanolate of zafirlukast, process for manufacture and pharmaceutical compositions thereof
IL140096A0 (en) * 2000-12-05 2002-02-10 Internat Specialty Products Is Process for preparation of zafirlukast
US6982251B2 (en) 2000-12-20 2006-01-03 Schering Corporation Substituted 2-azetidinones useful as hypocholesterolemic agents
US7071181B2 (en) 2001-01-26 2006-07-04 Schering Corporation Methods and therapeutic combinations for the treatment of diabetes using sterol absorption inhibitors
US20060287254A1 (en) * 2001-01-26 2006-12-21 Schering Corporation Use of substituted azetidinone compounds for the treatment of sitosterolemia
ATE331512T1 (de) 2001-01-26 2006-07-15 Schering Corp Verwendung azetidinone-substituierter verbindungen zur behandlung der sitosterolhämie
MEP27808A (en) * 2001-01-26 2010-10-10 Schering Corp Combinations of peroxisome proliferator-activated receptor (ppar) activator(s) and sterol absorption inhibitor(s) and treatments for vascular indications
CA2453182A1 (en) * 2001-07-10 2003-01-23 Meredith L. Greene Crystalline thiazine oxazolidinones
CA2455050C (en) * 2001-08-15 2007-02-20 Pharmacia & Upjohn Company Crystals including a malic acid salt of n-[2-(diethylamino) ethyl]-5-[(5-fluoro-2-oxo-3h-indole-3-ylidene) methyl]-2, 4-dimethyl-1h-pyrrole-3-carboxamide, processes for its preparation and compositions thereof
JP2005504091A (ja) 2001-09-21 2005-02-10 シェーリング コーポレイション ステロール吸収阻害剤としてアゼチジノンを用いる黄色腫の処置
US7053080B2 (en) * 2001-09-21 2006-05-30 Schering Corporation Methods and therapeutic combinations for the treatment of obesity using sterol absorption inhibitors
AR040588A1 (es) * 2002-07-26 2005-04-13 Schering Corp Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa
WO2004043457A1 (en) 2002-11-06 2004-05-27 Schering Corporation Cholesterol absorptions inhibitors for the treatment of autoimmune disorders
US7459442B2 (en) * 2003-03-07 2008-12-02 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
MXPA05009501A (es) * 2003-03-07 2005-10-18 Schering Corp Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia.
CA2517571C (en) * 2003-03-07 2011-07-05 Schering Corporation Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof
EP1606287B1 (en) 2003-03-07 2013-10-02 Merck Sharp & Dohme Corp. Substituted azetidinone compounds, formulations and uses thereof for the treatment of hypercholesterolemia
US20090317476A1 (en) * 2003-07-31 2009-12-24 Robinson Cynthia B Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
US20050026882A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a leukotriene receptor antagonist for treatment of asthma or chronic obstructive pulmonary disease
US20050113410A1 (en) * 2003-11-03 2005-05-26 Mark Tawa Pharmaceutical salts of zafirlukast
MY142017A (en) * 2004-03-19 2010-08-16 Nestec Sa Composition comprising all essential nutrients of a fruit or a plant material with increased stability and bioavailability and process of forming the same
ITMI20041032A1 (it) * 2004-05-24 2004-08-24 Neuroscienze S C A R L Compositi farmaceutici
EP1855651A4 (en) * 2005-03-03 2011-06-15 Elan Pharma Int Ltd NANOPARTICLE COMPOSITIONS OF HETEROCYCLIC AMID DERIVATIVES
US20070197467A1 (en) * 2006-02-06 2007-08-23 Srinivasulu Rangineni Zafirlukast compositions
US20090012146A1 (en) * 2007-07-02 2009-01-08 Giridhar Reddy Buggana Solubility-enhanced pharmaceutical compositions comprising zafirlukast
JP2010535234A (ja) * 2007-07-30 2010-11-18 オースペックス・ファーマシューティカルズ・インコーポレイテッド 置換インドール
US20090149662A1 (en) * 2007-12-05 2009-06-11 Raghupathi Reddy Anumula Processes for preparing zafirlukast
WO2014012954A1 (en) 2012-07-18 2014-01-23 Takeda Gmbh Treatment of partly controlled or uncontrolled severe asthma
WO2015110394A1 (en) 2014-01-22 2015-07-30 Takeda Gmbh Treatment of partly controlled or uncontrolled severe asthma with a pde4 inhibitor (and in combination with a leukotriene modifier)
PT109030B (pt) * 2015-12-15 2019-09-25 Hovione Farmaciência, S.A. Preparação de partículas inaláveis de zafirlucaste
BR112019015721A2 (pt) 2017-01-30 2020-03-24 Western New England University Inibidores de tiol isomerases e uso dos mesmos
US10752585B2 (en) 2017-12-28 2020-08-25 Council Of Scientific & Industrial Research Process for the preparation of Zafirlukast and analogs thereof
US12403122B2 (en) 2021-05-19 2025-09-02 Quercis Pharma AG Method for treating amyotrophic lateral sclerosis using quercetin-containing compositions
WO2023214391A1 (en) 2022-05-06 2023-11-09 Quercis Pharma AG Method for treating cancers and neurological diseases using quercetin-containing compositions

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607294D0 (en) * 1985-04-17 1986-04-30 Ici America Inc Heterocyclic amide derivatives
IL100091A (en) * 1990-12-12 1998-08-16 Zeneca Ltd Pharmaceutical compositions containing a physical form of n-[4-[5-(cyclopentyloxycarbonyl)amino-1-methyl indol-3-yl-methyl]-2-methylbenzenesulpho-namide and process for their preparation
GB9027018D0 (en) * 1990-12-12 1991-01-30 Ici Plc Heterocyclic compounds

Also Published As

Publication number Publication date
CA2056066A1 (en) 1992-06-13
CA2056066C (en) 2002-04-02
ATE131048T1 (de) 1995-12-15
FI101193B1 (fi) 1998-05-15
IT1256282B (it) 1995-11-29
JPH04266824A (ja) 1992-09-22
AP9100340A0 (en) 1992-01-31
IL100091A (en) 1998-08-16
CZ283181B6 (cs) 1998-01-14
JP2585495B2 (ja) 1997-02-26
ES2079589T3 (es) 1996-01-16
IE914310A1 (en) 1992-06-17
IE75348B1 (en) 1997-08-27
DE69115229T2 (de) 1996-05-09
HK81397A (en) 1997-06-27
NZ240939A (en) 1994-05-26
CN1043405C (zh) 1999-05-19
US5612367A (en) 1997-03-18
HU913865D0 (en) 1992-02-28
ITMI913324A0 (it) 1991-12-11
MX9102473A (es) 1992-06-01
ITMI913324A1 (it) 1993-06-11
US5993859A (en) 1999-11-30
KR920011493A (ko) 1992-07-24
CA2319308A1 (en) 1992-06-13
US6143775A (en) 2000-11-07
KR970005014A (ko) 1997-01-29
US5482963A (en) 1996-01-09
GB9126354D0 (en) 1992-02-12
AP285A (en) 1993-09-23
FI915826A0 (fi) 1991-12-11
GB2251791A (en) 1992-07-22
GB2251791B (en) 1995-05-17
IL100091A0 (en) 1992-08-18
HU213211B (en) 1997-03-28
GB9418154D0 (en) 1994-10-26
GB2280606A (en) 1995-02-08
FI101193B (fi) 1998-05-15
EP0490648B1 (en) 1995-12-06
AU656157B2 (en) 1995-01-27
TW276181B (fi) 1996-05-21
EP0490648A1 (en) 1992-06-17
FR2670488B1 (fr) 1994-01-28
CA2319308C (en) 2001-08-21
FR2670488A1 (fr) 1992-06-19
DE69115229D1 (de) 1996-01-18
HUT61281A (en) 1992-12-28
CS375691A3 (en) 1992-06-17
US5504216A (en) 1996-04-02
DK0490648T3 (da) 1996-05-06
CN1105705C (zh) 2003-04-16
HU211126A9 (en) 1995-10-30
CN1243827A (zh) 2000-02-09
HK81597A (en) 1997-06-27
SK279814B6 (sk) 1999-04-13
KR0183027B1 (ko) 1999-05-01
DE4140858A1 (de) 1992-06-17
CN1062291A (zh) 1992-07-01
MY106315A (en) 1995-04-29
GR3018318T3 (en) 1996-03-31
KR100207802B1 (ko) 1999-07-15
BE1004229A5 (fr) 1992-10-13
RU2106140C1 (ru) 1998-03-10
US5319097A (en) 1994-06-07
SK279813B6 (sk) 1999-04-13
PH30928A (en) 1997-12-23
GB2280606B (en) 1995-05-17
AU8899491A (en) 1992-06-18

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Owner name: ZENECA LIMITED

MA Patent expired