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FI915488L - Kondenserade heterocykliska foereningar, deras framstaellning och anvaendning. - Google Patents

Kondenserade heterocykliska foereningar, deras framstaellning och anvaendning. Download PDF

Info

Publication number
FI915488L
FI915488L FI915488A FI915488A FI915488L FI 915488 L FI915488 L FI 915488L FI 915488 A FI915488 A FI 915488A FI 915488 A FI915488 A FI 915488A FI 915488 L FI915488 L FI 915488L
Authority
FI
Finland
Prior art keywords
kondenserade
heterocykliska
foereningar
deras framstaellning
framstaellning och
Prior art date
Application number
FI915488A
Other languages
English (en)
Other versions
FI915488A0 (fi
FI102965B (fi
FI102965B1 (fi
Inventor
Giichi Goto
Yuji Ishihara
Masaomi Miyamoto
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FI915488A0 publication Critical patent/FI915488A0/fi
Publication of FI915488L publication Critical patent/FI915488L/fi
Application granted granted Critical
Publication of FI102965B publication Critical patent/FI102965B/fi
Publication of FI102965B1 publication Critical patent/FI102965B1/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Containers Having Bodies Formed In One Piece (AREA)
  • Hydrogenated Pyridines (AREA)
FI915488A 1990-11-22 1991-11-21 Kondensoituneet heterosykliset yhdisteet, niiden valmistus ja käyttö FI102965B1 (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP31989790 1990-11-22
JP7028691 1991-01-14
JP20935891 1991-08-21
JP24376891 1991-09-24

Publications (4)

Publication Number Publication Date
FI915488A0 FI915488A0 (fi) 1991-11-21
FI915488L true FI915488L (fi) 1992-05-23
FI102965B FI102965B (fi) 1999-03-31
FI102965B1 FI102965B1 (fi) 1999-03-31

Family

ID=27465225

Family Applications (2)

Application Number Title Priority Date Filing Date
FI982436A FI982436A7 (fi) 1990-11-22 1991-11-21 Kondensoituneet heterosykliset yhdisteet
FI915488A FI102965B1 (fi) 1990-11-22 1991-11-21 Kondensoituneet heterosykliset yhdisteet, niiden valmistus ja käyttö

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FI982436A FI982436A7 (fi) 1990-11-22 1991-11-21 Kondensoituneet heterosykliset yhdisteet

Country Status (19)

Country Link
US (1) US5273974A (fi)
EP (1) EP0487071B1 (fi)
JP (1) JP2650537B2 (fi)
KR (1) KR100211437B1 (fi)
CN (1) CN1036458C (fi)
AT (1) ATE124695T1 (fi)
AU (1) AU643337B2 (fi)
CA (1) CA2055947C (fi)
DE (1) DE69111029T2 (fi)
DK (1) DK0487071T3 (fi)
ES (1) ES2074205T3 (fi)
FI (2) FI982436A7 (fi)
GR (1) GR3017366T3 (fi)
HU (2) HU214573B (fi)
IE (1) IE68346B1 (fi)
NO (1) NO179868C (fi)
NZ (1) NZ240676A (fi)
RU (1) RU2095361C1 (fi)
TW (1) TW197435B (fi)

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TW263504B (fi) * 1991-10-03 1995-11-21 Pfizer
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TW218875B (fi) * 1992-03-09 1994-01-11 Takeda Pharm Industry Co Ltd
EP0567090B1 (en) 1992-04-24 2000-07-26 Takeda Chemical Industries, Ltd. Benzoxazepine derivatives as cholinesterase inhibitors
TW248556B (fi) * 1993-01-18 1995-06-01 Takeda Pharm Industry Co
US5620973A (en) * 1993-11-30 1997-04-15 Takeda Chemical Industries, Ltd. Tetracyclic condensed heterocyclic compounds and their use
US5656661A (en) * 1994-07-27 1997-08-12 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
JPH10506615A (ja) * 1994-07-27 1998-06-30 ザ、プロクター、エンド、ギャンブル、カンパニー 抗炎症剤として有用なジヒドロベンゾフラン及び関連化合物
US5684031A (en) * 1996-02-01 1997-11-04 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US5672620A (en) * 1996-02-01 1997-09-30 The Procter & Gamble Company Dihydrobenzofuran and related compounds useful as anti-inflammatory agents
US6251938B1 (en) 1996-12-18 2001-06-26 Teva Pharmaceutical Industries, Ltd., Phenylethylamine derivatives
JP4222632B2 (ja) 1996-12-18 2009-02-12 テバ・ファーマシューティカル・インダストリーズ・リミテッド アミノインダン誘導体
US5962535A (en) * 1997-01-17 1999-10-05 Takeda Chemical Industries, Ltd. Composition for alzheimer's disease
DE69802498T2 (de) * 1997-01-17 2002-07-04 Takeda Chemical Industries, Ltd. Idebenon enthaltendes kombinationspräparat zur alzheimer behandlung
AU6852898A (en) 1997-04-17 1998-11-11 Takeda Chemical Industries Ltd. Thermogenic composition and benzazepine thermogenics
RU2222815C2 (ru) * 1997-10-09 2004-01-27 Дексел Фарма Текнолоджис Элтиди. Лекарственная форма для доставки и непосредственного локализованного освобождения желаемого агента в желудочно-кишечном тракте животного и способ доставки желаемого агента в желудочно-кишечный тракт животного (варианты)
EP1042314B1 (en) * 1997-12-19 2003-03-19 G.D. Searle & Co. Method of preparing enantiomerically-enriched tetrahydrobenzothiepine oxides
US6500820B1 (en) 1998-04-23 2002-12-31 Takeda Chemical Industries, Ltd. Pharmaceutical composition for neurotrophic action
KR100648869B1 (ko) 1998-09-30 2007-02-28 다케다 야쿠힌 고교 가부시키가이샤 방광 배출력 개선제
EP1157989B1 (en) 1999-03-03 2004-09-22 Eisai Co., Ltd. Fluorides of 4-substituted piperidine derivatives
CA2414976A1 (en) * 2000-07-04 2002-01-10 Takeda Chemical Industries, Ltd. Gpr14 antagonistic agent
US20040053826A1 (en) * 2000-08-10 2004-03-18 Yoshio Matsumoto Uses of polypeptides
CN1317276C (zh) * 2000-09-29 2007-05-23 中国科学院上海药物研究所 一类吲哚基哌啶类化合物及其制备方法和用途
KR100614862B1 (ko) 2001-12-28 2006-08-22 다케다 야쿠힌 고교 가부시키가이샤 배뇨 장애 예방제/치료제
US20040010038A1 (en) * 2002-02-27 2004-01-15 Eran Blaugrund Propargylamino indan derivatives and propargylamino tetralin derivatives as brain-selective MAO inhibitors
NZ535880A (en) * 2002-04-16 2007-11-30 Schering Corp Tricyclic thrombin receptor antagonists
JP4675103B2 (ja) 2002-06-14 2011-04-20 富山化学工業株式会社 脳機能を改善する医薬組成物および脳機能を改善するための方法
KR100897642B1 (ko) 2002-12-20 2009-05-14 글락소 그룹 리미티드 신경 장애 치료용 벤즈아제핀 유도체
JPWO2006004201A1 (ja) * 2004-07-01 2008-04-24 エーザイ・アール・アンド・ディー・マネジメント株式会社 神経再生促進剤
US20080188510A1 (en) * 2005-05-23 2008-08-07 Eisai R & D Management Co., Ltd. Novel methods using zonisamide
ES2632638T3 (es) * 2005-12-09 2017-09-14 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Ladostigilo de baja dosis para el tratamiento de la deficiencia cognitiva
TW200744576A (en) * 2006-02-24 2007-12-16 Teva Pharma Propargylated aminoindans, processes for preparation, and uses thereof
AU2009272486A1 (en) * 2008-07-18 2010-01-21 Takeda Pharmaceutical Company Limited. Benzazepine derivatives and their use as hstamine H3 antagonists
CA2789014C (en) 2010-02-09 2019-01-15 Michela Gallagher Methods and compositions for improving cognitive function
US20140206667A1 (en) 2012-11-14 2014-07-24 Michela Gallagher Methods and compositions for treating schizophrenia
EP2968237A4 (en) 2013-03-15 2016-08-31 Univ Johns Hopkins METHOD AND COMPOSITIONS FOR IMPROVING COGNITIVE FUNCTION
ES2881081T3 (es) 2013-03-15 2021-11-26 Agenebio Inc Procedimientos y composiciones para mejorar la función cognitiva
CA2986598C (en) 2015-05-22 2023-09-26 Agenebio, Inc. Extended release pharmaceutical compositions of levetiracetam
CN109880635B (zh) * 2019-03-19 2021-02-02 石家庄晶奥量新材料有限公司 含有二苯并呋喃并含氧杂环类液晶化合物和组合物及应用

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US4208417A (en) * 1978-06-29 1980-06-17 Pharmindustrie Indole derivatives and their use as anxiolytics
DK623586A (da) * 1985-12-27 1987-06-28 Eisai Co Ltd Piperidinderivater eller salte deraf og farmaceutiske kompositioner indeholdende forbindelserne
KR910006138B1 (ko) * 1986-09-30 1991-08-16 에자이 가부시끼가이샤 환상아민 유도체
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FR2640266B2 (fr) * 1988-07-12 1992-07-10 Synthelabo Derives de (hydroxy-1 piperidinyl-2 alkyl) indolones-2, quinoleinones-2, benzo(b)azepinones-2 et benzimidazolones-2, leur preparation et leur application en therapeutique
JP2969359B2 (ja) * 1989-01-13 1999-11-02 武田薬品工業株式会社 環状アミン化合物
CA2023492A1 (en) * 1989-08-31 1991-03-01 Barry Clifford Lange Herbicidal glutarimides
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Also Published As

Publication number Publication date
ES2074205T3 (es) 1995-09-01
FI915488A0 (fi) 1991-11-21
AU643337B2 (en) 1993-11-11
KR100211437B1 (ko) 1999-08-02
FI982436L (fi) 1998-11-10
JPH05140149A (ja) 1993-06-08
DE69111029D1 (de) 1995-08-10
FI102965B (fi) 1999-03-31
HU913643D0 (en) 1992-02-28
FI982436A0 (fi) 1998-11-10
US5273974A (en) 1993-12-28
CN1036458C (zh) 1997-11-19
HUT59676A (en) 1992-06-29
JP2650537B2 (ja) 1997-09-03
DK0487071T3 (da) 1995-10-30
FI102965B1 (fi) 1999-03-31
NO914558D0 (no) 1991-11-21
CA2055947C (en) 2002-03-12
NO179868B (no) 1996-09-23
NO179868C (no) 1997-01-02
RU2095361C1 (ru) 1997-11-10
FI982436A7 (fi) 1998-11-10
DE69111029T2 (de) 1995-12-14
AU8804591A (en) 1992-05-28
CA2055947A1 (en) 1992-05-23
EP0487071B1 (en) 1995-07-05
HU214573B (hu) 2000-04-28
NZ240676A (en) 1993-05-26
GR3017366T3 (en) 1995-12-31
IE914053A1 (en) 1992-06-03
CN1062143A (zh) 1992-06-24
IE68346B1 (en) 1996-06-12
ATE124695T1 (de) 1995-07-15
TW197435B (fi) 1993-01-01
EP0487071A1 (en) 1992-05-27
HU211130A9 (en) 1995-10-30
KR920009823A (ko) 1992-06-25
NO914558L (no) 1992-05-25

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