FI906084A0 - Menetelmä uusien terapeuttisesti käyttökelpoisten 5-(2-metyyli-4,4,4-trifluoributyylikarbamoyyli)indolijohdannaisten valmistamiseksi - Google Patents

Menetelmä uusien terapeuttisesti käyttökelpoisten 5-(2-metyyli-4,4,4-trifluoributyylikarbamoyyli)indolijohdannaisten valmistamiseksi

Info

Publication number: FI906084A0
Authority: FI; Finland
Prior art keywords: trifluorobutylcarbamoyl; methyl; preparation; therapeutically useful; indole derivatives
Prior art date: 1989-12-11

Application number

FI906084A

Other languages

English (en)

Swedish (sv)

Other versions

FI906084L (fi

FI95029B (fi

FI95029C (fi

Inventor

Robert Toms Jacobs

Original Assignee

Ici Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-12-11

Filing date

1990-12-11

Publication date

1990-12-11

1990-12-11 Application filed by Ici Plc filed Critical Ici Plc

1990-12-11 Publication of FI906084A0 publication Critical patent/FI906084A0/fi

1991-06-12 Publication of FI906084L publication Critical patent/FI906084L/fi

1995-08-31 Publication of FI95029B publication Critical patent/FI95029B/fi

1995-12-11 Application granted granted Critical

1995-12-11 Publication of FI95029C publication Critical patent/FI95029C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
- C07C211/02—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C211/15—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Immunology (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Indole Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

FI906084A 1989-12-11 1990-12-11 Menetelmä uusien terapeuttisesti käyttökelpoisten 5-(2-metyyli-4,4,4-trifluoributyylikarbamoyyli)indolijohdannaisten valmistamiseksi FI95029C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
GB898927981A GB8927981D0 (en)	1989-12-11	1989-12-11	Carbamoyl derivative
GB8927981		1989-12-11

Publications (4)

Publication Number	Publication Date
FI906084A0 true FI906084A0 (fi)	1990-12-11
FI906084L FI906084L (fi)	1991-06-12
FI95029B FI95029B (fi)	1995-08-31
FI95029C FI95029C (fi)	1995-12-11

Family

ID=10667774

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI906084A FI95029C (fi)	1989-12-11	1990-12-11	Menetelmä uusien terapeuttisesti käyttökelpoisten 5-(2-metyyli-4,4,4-trifluoributyylikarbamoyyli)indolijohdannaisten valmistamiseksi

Country Status (31)

Country	Link
EP (1)	EP0432984B1 (fi)
JP (1)	JPH0822849B2 (fi)
KR (1)	KR100192999B1 (fi)
CN (1)	CN1025786C (fi)
AP (1)	AP192A (fi)
AT (1)	ATE163641T1 (fi)
AU (1)	AU642182B2 (fi)
BG (2)	BG50606A3 (fi)
CA (1)	CA2031897C (fi)
CZ (1)	CZ614690A3 (fi)
DE (1)	DE69032083T2 (fi)
DK (1)	DK0432984T3 (fi)
ES (1)	ES2112832T3 (fi)
FI (1)	FI95029C (fi)
GB (2)	GB8927981D0 (fi)
GR (1)	GR3026279T3 (fi)
HR (1)	HRP930326B1 (fi)
HU (2)	HU210441B (fi)
IE (1)	IE904448A1 (fi)
IL (1)	IL96621A (fi)
MY (1)	MY106363A (fi)
NO (1)	NO174198C (fi)
PL (2)	PL167449B1 (fi)
PT (1)	PT96154B (fi)
RO (1)	RO108562B1 (fi)
RU (1)	RU2002740C1 (fi)
SI (1)	SI9012330A (fi)
SK (1)	SK278528B6 (fi)
TW (1)	TW219329B (fi)
YU (1)	YU48218B (fi)
ZA (1)	ZA909898B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2063479T3 (es) *	1990-05-04	1995-01-01	Ciba Geigy Ag	Indoles substituidos.
GB9020338D0 (en) *	1990-09-18	1990-10-31	Lilly Industries Ltd	Pharmaceutical compounds
GB9026425D0 (en) *	1990-12-05	1991-01-23	Ici Plc	Process
GB9026427D0 (en) *	1990-12-05	1991-01-23	Ici Plc	Chemical process
GB9119001D0 (en) *	1991-09-05	1991-10-23	Ici Plc	Pharmaceutical agents
ES2050611B1 (es) *	1992-10-08	1994-12-16	Ici Plc	Una nueva forma fisica de un derivado de carbamoilindol con propiedades antagonistas de leucotrienos.
GR1001368B (el) *	1992-10-08	1993-10-29	Ici Plc	Φαρμακευτικοί φορείς.
EP0781283B1 (en) *	1994-09-16	2001-06-06	Takeda Chemical Industries, Ltd.	Triazolopyridazines process and intermediates for their preparation and their use as medicaments
US7166638B2 (en) *	2003-05-27	2007-01-23	Nicox S.A.	Statin derivatives
KR20070091607A (ko) *	2004-10-12	2007-09-11	디코드 제네틱스, 아이엔씨.	폐쇄성 동맥 질환용의 설폰아미드 주변 치환된바이사이클릭 화합물
NZ560513A (en) *	2005-02-25	2010-07-30	Ono Pharmaceutical Co	Indole compound and use thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4524152A (en) *	1982-12-30	1985-06-18	Pennwalt Corporation	1-Cyano-3-(fluoroalkyl)guanidines for lowering blood pressure
GB8623429D0 (en) *	1985-10-17	1986-11-05	Ici America Inc	Carboximide derivatives
US4837235A (en) *	1985-10-17	1989-06-06	Ici Americas Inc.	Indole and indazole keto sulphones as leukotriene antagonists
MY103259A (en) *	1987-04-15	1993-05-29	Ici America Inc	Aliphatic carboxamides
GB8906032D0 (en) *	1988-04-14	1989-04-26	Ici America Inc	Hetera-aliphatic carboxamides
GB9026425D0 (en) *	1990-12-05	1991-01-23	Ici Plc	Process

1989
- 1989-12-11 GB GB898927981A patent/GB8927981D0/en active Pending
1990
- 1990-12-10 HU HU908137A patent/HU210441B/hu not_active IP Right Cessation
- 1990-12-10 RU SU04831920A patent/RU2002740C1/ru not_active IP Right Cessation
- 1990-12-10 SI SI9012330A patent/SI9012330A/sl unknown
- 1990-12-10 SK SK6146-90A patent/SK278528B6/sk unknown
- 1990-12-10 GB GB9026797A patent/GB2238790B/en not_active Revoked
- 1990-12-10 RO RO146517A patent/RO108562B1/ro unknown
- 1990-12-10 DK DK90313373T patent/DK0432984T3/da active
- 1990-12-10 DE DE69032083T patent/DE69032083T2/de not_active Expired - Lifetime
- 1990-12-10 EP EP90313373A patent/EP0432984B1/en not_active Expired - Lifetime
- 1990-12-10 AP APAP/P/1990/000230A patent/AP192A/en active
- 1990-12-10 ZA ZA909898A patent/ZA909898B/xx unknown
- 1990-12-10 PL PL90304868A patent/PL167449B1/pl unknown
- 1990-12-10 BG BG095502A patent/BG50606A3/xx unknown
- 1990-12-10 YU YU233090A patent/YU48218B/sh unknown
- 1990-12-10 ES ES90313373T patent/ES2112832T3/es not_active Expired - Lifetime
- 1990-12-10 IL IL9662190A patent/IL96621A/en not_active IP Right Cessation
- 1990-12-10 AT AT90313373T patent/ATE163641T1/de not_active IP Right Cessation
- 1990-12-10 CZ CS906146A patent/CZ614690A3/cs not_active IP Right Cessation
- 1990-12-10 AU AU67917/90A patent/AU642182B2/en not_active Ceased
- 1990-12-10 BG BG093426A patent/BG60015B2/bg unknown
- 1990-12-10 IE IE444890A patent/IE904448A1/en not_active IP Right Cessation
- 1990-12-10 CA CA002031897A patent/CA2031897C/en not_active Expired - Fee Related
- 1990-12-10 NO NO905327A patent/NO174198C/no unknown
- 1990-12-10 MY MYPI90002157A patent/MY106363A/en unknown
- 1990-12-10 PL PL90288184A patent/PL166516B1/pl unknown
- 1990-12-11 JP JP2419290A patent/JPH0822849B2/ja not_active Expired - Lifetime
- 1990-12-11 CN CN90110406A patent/CN1025786C/zh not_active Expired - Lifetime
- 1990-12-11 KR KR1019900020547A patent/KR100192999B1/ko not_active Expired - Lifetime
- 1990-12-11 FI FI906084A patent/FI95029C/fi not_active IP Right Cessation
- 1990-12-11 PT PT96154A patent/PT96154B/pt not_active IP Right Cessation
- 1990-12-20 TW TW079110705A patent/TW219329B/zh not_active IP Right Cessation
1993
- 1993-03-11 HR HRP-2330/90A patent/HRP930326B1/xx not_active IP Right Cessation
1995
- 1995-06-12 HU HU95P/P00183P patent/HU210877A9/hu unknown
1998
- 1998-03-05 GR GR980400270T patent/GR3026279T3/el unknown

Also Published As

Publication number	Publication date
JPH0770061A (ja)	1995-03-14
CA2031897A1 (en)	1991-06-12
HUT56345A (en)	1991-08-28
DE69032083T2 (de)	1998-07-16
BG50606A3 (bg)	1992-09-15
DE69032083D1 (de)	1998-04-09
HK1003830A1 (en)	1998-11-06
ZA909898B (en)	1991-08-28
GB8927981D0 (en)	1990-02-14
IE904448A1 (en)	1991-06-19
YU233090A (sh)	1993-05-28
TW219329B (fi)	1994-01-21
CN1025786C (zh)	1994-08-31
FI906084L (fi)	1991-06-12
GB2238790A (en)	1991-06-12
KR100192999B1 (ko)	1999-06-15
DK0432984T3 (da)	1998-11-30
JPH0822849B2 (ja)	1996-03-06
PT96154B (pt)	1998-05-29
PL166516B1 (pl)	1995-05-31
AU642182B2 (en)	1993-10-14
HU210877A9 (en)	1995-09-28
PL167449B1 (pl)	1995-09-30
MY106363A (en)	1995-05-30
EP0432984A2 (en)	1991-06-19
ATE163641T1 (de)	1998-03-15
AU6791790A (en)	1991-06-13
CA2031897C (en)	2001-12-18
SK614690A3 (en)	1997-08-06
AP9000230A0 (en)	1991-01-31
EP0432984A3 (en)	1992-04-22
CZ282068B6 (cs)	1997-05-14
IL96621A0 (en)	1991-09-16
CZ614690A3 (en)	1997-05-14
IL96621A (en)	1994-11-28
HRP930326B1 (en)	1998-12-31
ES2112832T3 (es)	1998-04-16
SI9012330A (en)	1997-12-31
HU210441B (en)	1995-04-28
NO905327D0 (no)	1990-12-10
KR910011780A (ko)	1991-08-07
FI95029B (fi)	1995-08-31
BG60015B2 (bg)	1993-06-30
SK278528B6 (en)	1997-08-06
RO108562B1 (ro)	1994-06-30
EP0432984B1 (en)	1998-03-04
PT96154A (pt)	1991-09-30
AP192A (en)	1992-06-30
YU48218B (sh)	1997-08-22
CN1053604A (zh)	1991-08-07
GB9026797D0 (en)	1991-01-30
NO174198B (no)	1993-12-20
GB2238790B (en)	1993-06-30
FI95029C (fi)	1995-12-11
RU2002740C1 (ru)	1993-11-15
HRP930326A2 (en)	1996-06-30
NO174198C (no)	1994-04-06
HU908137D0 (en)	1991-06-28
PL288184A1 (en)	1992-04-21
NO905327L (no)	1991-06-12
GR3026279T3 (en)	1998-06-30

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Legal Events

Date	Code	Title	Description
1994-03-23	GB	Transfer or assigment of application	Owner name: ZENECA LIMITED
1995-08-02	BB	Publication of examined application
2004-08-31	MM	Patent lapsed	Owner name: ZENECA LIMITED