FI906008A0 - Förfarande för stabilisering av en vattenhaltig blandning av heterocyklisk förening - Google Patents
Förfarande för stabilisering av en vattenhaltig blandning av heterocyklisk föreningInfo
- Publication number
- FI906008A0 FI906008A0 FI906008A FI906008A FI906008A0 FI 906008 A0 FI906008 A0 FI 906008A0 FI 906008 A FI906008 A FI 906008A FI 906008 A FI906008 A FI 906008A FI 906008 A0 FI906008 A0 FI 906008A0
- Authority
- FI
- Finland
- Prior art keywords
- methionine
- stabilizing
- heterocyclic compound
- stabilized
- aqueous mixture
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title abstract 2
- 230000000087 stabilizing effect Effects 0.000 title abstract 2
- 150000002391 heterocyclic compounds Chemical class 0.000 title 1
- FFEARJCKVFRZRR-UHFFFAOYSA-N L-Methionine Natural products CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 abstract 2
- 239000000935 antidepressant agent Substances 0.000 abstract 2
- 229940005513 antidepressants Drugs 0.000 abstract 2
- 238000002360 preparation method Methods 0.000 abstract 2
- FFEARJCKVFRZRR-SCSAIBSYSA-N D-methionine Chemical compound CSCC[C@@H](N)C(O)=O FFEARJCKVFRZRR-SCSAIBSYSA-N 0.000 abstract 1
- 229930182818 D-methionine Natural products 0.000 abstract 1
- 239000004470 DL Methionine Substances 0.000 abstract 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 abstract 1
- 229930195722 L-methionine Natural products 0.000 abstract 1
- UEQUQVLFIPOEMF-UHFFFAOYSA-N Mianserin Chemical compound C1C2=CC=CC=C2N2CCN(C)CC2C2=CC=CC=C21 UEQUQVLFIPOEMF-UHFFFAOYSA-N 0.000 abstract 1
- 229960000836 amitriptyline Drugs 0.000 abstract 1
- KRMDCWKBEZIMAB-UHFFFAOYSA-N amitriptyline Chemical compound C1CC2=CC=CC=C2C(=CCCN(C)C)C2=CC=CC=C21 KRMDCWKBEZIMAB-UHFFFAOYSA-N 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229930182817 methionine Natural products 0.000 abstract 1
- 229960004452 methionine Drugs 0.000 abstract 1
- 235000006109 methionine Nutrition 0.000 abstract 1
- 229960003955 mianserin Drugs 0.000 abstract 1
- 229960001785 mirtazapine Drugs 0.000 abstract 1
- RONZAEMNMFQXRA-UHFFFAOYSA-N mirtazapine Chemical compound C1C2=CC=CN=C2N2CCN(C)CC2C2=CC=CC=C21 RONZAEMNMFQXRA-UHFFFAOYSA-N 0.000 abstract 1
- 150000002978 peroxides Chemical class 0.000 abstract 1
- -1 septiline Chemical compound 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/20—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurosurgery (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP89203092 | 1989-12-06 | ||
| EP89203092 | 1989-12-06 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI906008A0 true FI906008A0 (sv) | 1990-12-05 |
| FI906008L FI906008L (sv) | 1991-06-07 |
| FI97689B FI97689B (sv) | 1996-10-31 |
| FI97689C FI97689C (sv) | 1997-02-10 |
Family
ID=8202518
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI906008A FI97689C (sv) | 1989-12-06 | 1990-12-05 | Förfarande för stabilisering av en vattenhaltig blandning av heterocyklisk förening |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5082864A (sv) |
| EP (1) | EP0431663B1 (sv) |
| JP (1) | JP2977912B2 (sv) |
| KR (1) | KR0185377B1 (sv) |
| AT (1) | ATE99943T1 (sv) |
| AU (1) | AU628768B2 (sv) |
| CA (1) | CA2030773C (sv) |
| DE (1) | DE69005992T2 (sv) |
| DK (1) | DK0431663T3 (sv) |
| ES (1) | ES2062310T3 (sv) |
| FI (1) | FI97689C (sv) |
| IE (1) | IE63985B1 (sv) |
| NZ (1) | NZ236332A (sv) |
| PT (1) | PT96096B (sv) |
| ZA (1) | ZA909568B (sv) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USH1591H (en) * | 1992-10-09 | 1996-09-03 | Fulcher; John | Preparation of flavor-enhanced reduced calorie fried foods |
| IL107887A (en) * | 1992-12-08 | 2003-07-06 | Ambi Inc | Stabilized lanthionine containing bacteriocin compositions |
| US6197830B1 (en) | 1995-09-22 | 2001-03-06 | Bruce M. Frome | Method for achieving relief from sympathetically mediated pain |
| EP0813873B1 (en) * | 1996-06-19 | 2002-02-13 | Akzo Nobel N.V. | Pharmaceutical composition comprising mirtazapine and one or more selective serotonin reuptake inhibitors |
| IL121076A (en) * | 1996-06-19 | 2000-10-31 | Akzo Nobel Nv | Pharmaceutical combinations comprising mirtazapine and one or more selective serotonin reuptake inhibitors |
| TW587938B (en) * | 1997-03-27 | 2004-05-21 | Akzo Nobel Nv | Pharmaceutical composition for the treatment and/or prophylaxis of psychotic disorder |
| DE69913116T2 (de) * | 1998-04-02 | 2004-06-03 | Akzo Nobel N.V. | Orale flüssige lösung enthaltend das antidepressivum mirtazapine |
| US6211171B1 (en) | 1998-05-19 | 2001-04-03 | Dalhousie University | Use of antidepressants for local analgesia |
| US6495534B2 (en) | 2000-05-15 | 2002-12-17 | Pharmacia & Upjohn Spa | Stabilized aqueous suspensions for parenteral use |
| AU2002237847A1 (en) * | 2001-02-12 | 2002-08-28 | Akzo Nobel N.V | Methods for improving the treatment of major depression by genotyping for the gene for apolipoproteine e4 |
| US6399310B1 (en) | 2001-02-12 | 2002-06-04 | Akzo Nobel N.V. | Methods for improving the therapeutic response of humans having major depression and carrying the gene for apolipoprotein E4 |
| US20030105082A1 (en) * | 2001-12-03 | 2003-06-05 | Murphy Greer Marechal | Methods for improving the therapeutic response of humans having major depression and carrying the gene for apolipoprotein E4 |
| US20050215552A1 (en) * | 2002-05-17 | 2005-09-29 | Gadde Kishore M | Method for treating obesity |
| CA2522708C (en) | 2003-04-29 | 2013-05-28 | Orexigen Therapeutics, Inc. | Compositions for affecting weight loss |
| US7838029B1 (en) * | 2003-07-31 | 2010-11-23 | Watson Laboratories, Inc. | Mirtazapine solid dosage forms |
| JP2007517901A (ja) * | 2004-01-13 | 2007-07-05 | デューク・ユニバーシティー | 体重の減少に作用する鎮痙剤及び抗精神病剤の組成物 |
| US20060039866A1 (en) * | 2004-08-20 | 2006-02-23 | Cypress Bioscience, Inc. | Method for treating sleep-related breathing disorders |
| EP1796635A2 (en) * | 2004-09-14 | 2007-06-20 | Molecular Therapeutics, Inc. | D-methionine formulation with improved biopharmaceutical properties |
| US20060122127A1 (en) * | 2004-11-17 | 2006-06-08 | Cypress Bioscience, Inc. | Methods for reducing the side effects associated with mirtzapine treatment |
| ES2761812T3 (es) * | 2005-11-22 | 2020-05-21 | Nalpropion Pharmaceuticals Inc | Composición y métodos de aumento de la sensibilidad a la insulina |
| CA2637359A1 (en) * | 2006-01-17 | 2007-07-26 | The Regents Of The University Of Colorado | Central administration of stable formulations of therapeutic agents for cns conditions |
| US8916195B2 (en) | 2006-06-05 | 2014-12-23 | Orexigen Therapeutics, Inc. | Sustained release formulation of naltrexone |
| KR101971218B1 (ko) | 2006-11-09 | 2019-08-27 | 오렉시젠 세러퓨틱스 인크. | 신속하게 용해되는 중간층을 포함하는 층상의 약제학적 제형 |
| AU2007319472B2 (en) | 2006-11-09 | 2013-01-17 | Nalpropion Pharmaceuticals Llc | Methods Of Administering Weight Loss Medications |
| EP2167096A4 (en) * | 2007-06-13 | 2010-07-14 | Cypress Bioscience Inc | IMPROVING TOLERANCE TO MIRTAZAPINE AND A SECOND ACTIVE INGREDIENT BY THE COMBINED USE OF THEM |
| WO2009158114A1 (en) * | 2008-05-30 | 2009-12-30 | Orexigen Therapeutics, Inc. | Methods for treating visceral fat conditions |
| EP2523557B1 (en) | 2010-01-11 | 2019-09-25 | Nalpropion Pharmaceuticals, Inc. | Methods of providing weight loss therapy in patients with major depression |
| PT2858640T (pt) | 2012-06-06 | 2020-06-30 | Nalpropion Pharmaceuticals Llc | Composição para utilização num método de tratamento de excesso de peso e obesidade em doentes com alto risco cardiovascular |
| KR101652081B1 (ko) | 2014-12-30 | 2016-08-30 | 김인호 | 전극보일러 급탕시스템 |
| ES2874549T3 (es) | 2015-02-27 | 2021-11-05 | Dechra Ltd | Estimulación del apetito, control de la pérdida de peso, y tratamiento de la anorexia en perros y gatos |
| KR20170001494A (ko) | 2015-06-26 | 2017-01-04 | 김인호 | 전극보일러 전류제어시스템 |
| CN108853042B (zh) * | 2018-09-20 | 2021-03-26 | 北京哈三联科技有限责任公司 | 一种米氮平冻干口崩片及其制备方法和应用 |
| GR1009883B (el) * | 2019-06-07 | 2020-12-11 | Λαμδα Φαρμακευτικα Εργαστηρια Εφαρμοσμενης Ερευνας Και Αναπτυξης Α.Ε. | Ποσιμα φαρμακευτικα διαλυματα που περιλαμβανουν υδροχλωρικη νορτριπτυλινη |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2082910A (en) * | 1980-08-28 | 1982-03-17 | Berk Pharmaceuticals Ltd | Anti-depressant compositions |
| US4603131A (en) * | 1982-04-26 | 1986-07-29 | Bernstein Joel E | Method and composition for treating and preventing irritation of the mucous membranes of the nose |
| DE3247676A1 (de) * | 1982-12-23 | 1984-06-28 | A. Nattermann & Cie GmbH, 5000 Köln | Galenische form fuer amitriptylinoxid und verfahren zur herstellung |
-
1990
- 1990-11-20 AT AT90203064T patent/ATE99943T1/de not_active IP Right Cessation
- 1990-11-20 EP EP90203064A patent/EP0431663B1/en not_active Expired - Lifetime
- 1990-11-20 DK DK90203064.2T patent/DK0431663T3/da active
- 1990-11-20 DE DE90203064T patent/DE69005992T2/de not_active Expired - Lifetime
- 1990-11-20 ES ES90203064T patent/ES2062310T3/es not_active Expired - Lifetime
- 1990-11-22 IE IE422690A patent/IE63985B1/en not_active IP Right Cessation
- 1990-11-23 CA CA002030773A patent/CA2030773C/en not_active Expired - Fee Related
- 1990-11-28 ZA ZA909568A patent/ZA909568B/xx unknown
- 1990-12-03 US US07/621,480 patent/US5082864A/en not_active Expired - Lifetime
- 1990-12-04 NZ NZ236332A patent/NZ236332A/en unknown
- 1990-12-05 PT PT96096A patent/PT96096B/pt not_active IP Right Cessation
- 1990-12-05 AU AU67798/90A patent/AU628768B2/en not_active Ceased
- 1990-12-05 FI FI906008A patent/FI97689C/sv active IP Right Grant
- 1990-12-05 KR KR1019900019904A patent/KR0185377B1/ko not_active Expired - Fee Related
- 1990-12-06 JP JP2413592A patent/JP2977912B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0431663A1 (en) | 1991-06-12 |
| ES2062310T3 (es) | 1994-12-16 |
| IE904226A1 (en) | 1991-06-19 |
| US5082864A (en) | 1992-01-21 |
| AU6779890A (en) | 1991-06-13 |
| EP0431663B1 (en) | 1994-01-12 |
| PT96096B (pt) | 1998-02-27 |
| DE69005992T2 (de) | 1994-05-05 |
| KR910011250A (ko) | 1991-08-07 |
| ATE99943T1 (de) | 1994-01-15 |
| FI906008L (sv) | 1991-06-07 |
| DE69005992D1 (de) | 1994-02-24 |
| AU628768B2 (en) | 1992-09-17 |
| FI97689B (sv) | 1996-10-31 |
| IE63985B1 (en) | 1995-06-28 |
| FI97689C (sv) | 1997-02-10 |
| CA2030773A1 (en) | 1991-06-07 |
| ZA909568B (en) | 1991-09-25 |
| JP2977912B2 (ja) | 1999-11-15 |
| DK0431663T3 (da) | 1994-03-07 |
| CA2030773C (en) | 2001-07-24 |
| KR0185377B1 (ko) | 1999-05-01 |
| NZ236332A (en) | 1992-07-28 |
| PT96096A (pt) | 1991-09-30 |
| JPH05262651A (ja) | 1993-10-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BB | Publication of examined application | ||
| FG | Patent granted |
Owner name: AKZO N.V. |
|
| PC | Transfer of assignment of patent |
Owner name: N.V. ORGANON Free format text: N.V. ORGANON |