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FI872646L - Hydrofoba cis-platinakomplex, vilka funktionellt inkorporerats i liposomer. - Google Patents

Hydrofoba cis-platinakomplex, vilka funktionellt inkorporerats i liposomer. Download PDF

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Publication number
FI872646L
FI872646L FI872646A FI872646A FI872646L FI 872646 L FI872646 L FI 872646L FI 872646 A FI872646 A FI 872646A FI 872646 A FI872646 A FI 872646A FI 872646 L FI872646 L FI 872646L
Authority
FI
Finland
Prior art keywords
complex
platinum
liposomer
inkorporerats
hydrofoba
Prior art date
Application number
FI872646A
Other languages
English (en)
Other versions
FI85492C (fi
FI85492B (fi
FI872646A0 (fi
Inventor
Abdul R Khokhar
Gabriel Lopez-Berestein
Roman Perez-Soler
Original Assignee
Univ Texas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27120836&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI872646(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Texas filed Critical Univ Texas
Publication of FI872646A0 publication Critical patent/FI872646A0/fi
Publication of FI872646L publication Critical patent/FI872646L/fi
Application granted granted Critical
Publication of FI85492B publication Critical patent/FI85492B/fi
Publication of FI85492C publication Critical patent/FI85492C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F17/00—Metallocenes
    • C07F17/02—Metallocenes of metals of Groups 8, 9 or 10 of the Periodic Table

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Cosmetics (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
FI872646A 1985-10-18 1987-06-15 Foerfarande foer framstaellning av vid antitumoer kemoterapi anvaendbara hydrofoba platina(ii) fyrkoordinatkomplex. FI85492C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US78875085A 1985-10-18 1985-10-18
US78875085 1985-10-18
US91459186 1986-10-07
US06/914,591 US5041581A (en) 1985-10-18 1986-10-07 Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
PCT/US1986/002181 WO1987002364A1 (en) 1985-10-18 1986-10-17 Hydrophobic cis-platinum complexes efficiently incorporated into liposomes
US8602181 1986-10-17

Publications (4)

Publication Number Publication Date
FI872646A0 FI872646A0 (fi) 1987-06-15
FI872646L true FI872646L (fi) 1987-06-15
FI85492B FI85492B (fi) 1992-01-15
FI85492C FI85492C (fi) 1992-04-27

Family

ID=27120836

Family Applications (1)

Application Number Title Priority Date Filing Date
FI872646A FI85492C (fi) 1985-10-18 1987-06-15 Foerfarande foer framstaellning av vid antitumoer kemoterapi anvaendbara hydrofoba platina(ii) fyrkoordinatkomplex.

Country Status (10)

Country Link
US (3) US5041581A (fi)
EP (1) EP0248036B1 (fi)
KR (1) KR900003094B1 (fi)
AT (1) ATE77384T1 (fi)
CA (1) CA1312616C (fi)
DE (1) DE3685751T2 (fi)
DK (1) DK307787A (fi)
FI (1) FI85492C (fi)
IL (1) IL80349A (fi)
WO (1) WO1987002364A1 (fi)

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US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5434256A (en) * 1988-11-22 1995-07-18 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
JP2001501173A (ja) * 1996-08-23 2001-01-30 アルザ コーポレイション シスプラチン化合物を含有するリポソーム
US5843475A (en) * 1996-12-06 1998-12-01 Board Of Regents, The University Of Texas System Delivery and activation through liposome incorporation of diaminocyclohexane platinum (II) complexes
US6548541B1 (en) * 1999-04-21 2003-04-15 Unitech Pharmaceuticals, Inc. Carboplatin analogs for cancer treatment
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US9186322B2 (en) 2002-08-02 2015-11-17 Insmed Incorporated Platinum aggregates and process for producing the same
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US7879351B2 (en) * 2002-10-29 2011-02-01 Transave, Inc. High delivery rates for lipid based drug formulations, and methods of treatment thereof
US7160908B2 (en) * 2003-03-04 2007-01-09 Unitech Pharmaceuticals, Inc. Dynamic anticancer platinum compounds
US20070160656A1 (en) * 2003-05-02 2007-07-12 Dziewiszek Krzysztof J Lipid platinum complexes and methods of use thereof
US20080107721A1 (en) * 2003-05-20 2008-05-08 Jonathan Lewis Combination Chemotherapy Comprising A Liposomal Platinum Complex
AU2003233586A1 (en) * 2003-05-20 2005-01-21 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising capecitabine and a liposomal platinum complex
CA2526289A1 (en) * 2003-05-20 2004-12-02 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising 5-fluorouracil or a derivative thereof and a liposomal platinum complex
AU2003239510A1 (en) * 2003-05-20 2005-01-21 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising gemcitabine and a liposomal platinum complex
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US20070065522A1 (en) * 2004-03-18 2007-03-22 Transave, Inc. Administration of high potency platinum compound formulations by inhalation
EP1729786A4 (en) * 2004-03-18 2008-03-26 Transave Inc ADMINISTRATION OF CISPLATIN BY INHALATION
US20060034906A1 (en) * 2004-05-21 2006-02-16 Transave, Inc. Treatment of lung diseases and pre-lung disease conditions
KR20070089693A (ko) * 2004-11-08 2007-08-31 트랜세이브, 인코포레이티드 지질-기재 플래티넘 화합물 제형을 복막내 투여하여 암을치료하는 방법
US8895717B2 (en) 2005-04-15 2014-11-25 The Board Of Regents Of The University Of Texas System Delivery of siRNA by neutral lipid compositions
CN1913508B (zh) * 2005-08-08 2010-05-05 华为技术有限公司 基于正交频分复用的信号调制方法及其调制装置
US9107824B2 (en) 2005-11-08 2015-08-18 Insmed Incorporated Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
WO2007056264A2 (en) * 2005-11-08 2007-05-18 Transave, Inc. Methods of treating cancer with high potency lipid-based platinum compound formulations administered intraperitoneally
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WO2008137717A1 (en) 2007-05-04 2008-11-13 Transave, Inc. Compositions of multicationic drugs for reducing interactions with polyanionic biomolecules and methods and uses thereof
US9114081B2 (en) 2007-05-07 2015-08-25 Insmed Incorporated Methods of treating pulmonary disorders with liposomal amikacin formulations
US9333214B2 (en) 2007-05-07 2016-05-10 Insmed Incorporated Method for treating pulmonary disorders with liposomal amikacin formulations
US9119783B2 (en) 2007-05-07 2015-09-01 Insmed Incorporated Method of treating pulmonary disorders with liposomal amikacin formulations
FR2945946B1 (fr) 2009-05-29 2011-08-26 Univ Victor Segalen Bordeaux 2 Formulations a compartiments multiples a base de molecules ou macromolecules amphiphiles fonctionnelles
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Also Published As

Publication number Publication date
FI85492C (fi) 1992-04-27
KR870700631A (ko) 1987-12-30
DK307787D0 (da) 1987-06-17
FI85492B (fi) 1992-01-15
US5178876A (en) 1993-01-12
ATE77384T1 (de) 1992-07-15
US5186940A (en) 1993-02-16
CA1312616C (en) 1993-01-12
FI872646A0 (fi) 1987-06-15
DK307787A (da) 1987-08-17
IL80349A (en) 1991-06-30
US5041581A (en) 1991-08-20
IL80349A0 (en) 1987-01-30
EP0248036B1 (en) 1992-06-17
DE3685751T2 (de) 1993-02-04
KR900003094B1 (ko) 1990-05-07
DE3685751D1 (de) 1992-07-23
EP0248036A1 (en) 1987-12-09
WO1987002364A1 (en) 1987-04-23

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Owner name: BOARD OF REGENTS