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FI870818A7 - Från normala humana tjocktarmsceller erhållen vävnadsplasminogenaktivator. - Google Patents

Från normala humana tjocktarmsceller erhållen vävnadsplasminogenaktivator. Download PDF

Info

Publication number
FI870818A7
FI870818A7 FI870818A FI870818A FI870818A7 FI 870818 A7 FI870818 A7 FI 870818A7 FI 870818 A FI870818 A FI 870818A FI 870818 A FI870818 A FI 870818A FI 870818 A7 FI870818 A7 FI 870818A7
Authority
FI
Finland
Prior art keywords
normal human
plasminogen activator
human colon
tissue plasminogen
colon cells
Prior art date
Application number
FI870818A
Other languages
English (en)
Finnish (fi)
Other versions
FI870818L (fi
FI870818A0 (fi
Inventor
Joseph Feder
William Robert Tolbert
Thomas W Rademacher
Raymond A Dwek
Raj B Parekh
Original Assignee
Monsanto Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Co filed Critical Monsanto Co
Publication of FI870818A0 publication Critical patent/FI870818A0/fi
Publication of FI870818L publication Critical patent/FI870818L/fi
Publication of FI870818A7 publication Critical patent/FI870818A7/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • CCHEMISTRY; METALLURGY
    • C08ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08BPOLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Polymers & Plastics (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
FI870818A 1986-02-26 1987-02-25 Från normala humana tjocktarmsceller erhållen vävnadsplasminogenaktivator. FI870818A7 (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83408086A 1986-02-26 1986-02-26
US06/929,950 US4751084A (en) 1986-02-26 1986-11-12 Tissue plasminogen activator from normal human colon cells

Publications (3)

Publication Number Publication Date
FI870818A0 FI870818A0 (fi) 1987-02-25
FI870818L FI870818L (fi) 1987-08-27
FI870818A7 true FI870818A7 (sv) 1987-08-27

Family

ID=27125681

Family Applications (1)

Application Number Title Priority Date Filing Date
FI870818A FI870818A7 (sv) 1986-02-26 1987-02-25 Från normala humana tjocktarmsceller erhållen vävnadsplasminogenaktivator.

Country Status (8)

Country Link
US (1) US4751084A (sv)
KR (1) KR900007084B1 (sv)
AU (2) AU598792B2 (sv)
DK (1) DK96787A (sv)
FI (1) FI870818A7 (sv)
NO (1) NO870772L (sv)
NZ (1) NZ219398A (sv)
PT (1) PT84356B (sv)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5108909A (en) * 1985-03-22 1992-04-28 Chiron Corporation Expression of TPA in mammalian cells
DK623186A (da) * 1985-12-23 1987-08-26 Chiron Corp Polypeptid med vaevsplasminogen-aktivator-virkning
US4927630A (en) * 1986-02-26 1990-05-22 Monsanto Company Tissue plasminogen activator from normal human colon cells
US5132214A (en) * 1986-04-09 1992-07-21 Monsanto Company Large scale production of plasminogen activator from normal human colon cells
DK173067B1 (da) * 1986-06-27 1999-12-13 Univ Washington Humant erythropoietin-gen, fremgangsmåde til ekspression deraf i transficerede cellelinier, de transficerede cellelinier sa
US4889922A (en) * 1986-08-13 1989-12-26 Monsanto Co. Monoclonal antibody specific for human colon fibroblast-derived T-PA
US4891312A (en) * 1986-08-13 1990-01-02 Monsanto Company Monoclonal antibody specific for human colon fibroblast-derived t-PA
US4833085A (en) * 1986-08-13 1989-05-23 Monsanto Company Monoclonal antibody specific for human colon fibroblast-derived t-PA
JPH08840B2 (ja) * 1986-11-14 1996-01-10 興和株式会社 抗pciモノクローナル抗体、これを用いた抗pciの精製法及び免疫学的測定法
JPH03501921A (ja) * 1987-05-18 1991-05-09 インテグレイテッド・ジェネティクス・インク 改良タンパク質分子、並びにその製造及び活性化方法
WO1989005862A1 (en) * 1987-12-09 1989-06-29 Invitron Corporation Human cell life extension
US5210037A (en) * 1988-03-22 1993-05-11 Centocor Incorporated Method to enhance TPA production
WO1989009257A1 (en) * 1988-03-22 1989-10-05 Invitron Corporation METHOD TO ENHANCE tPA PRODUCTION
US5218092A (en) * 1988-09-29 1993-06-08 Kyowa Hakko Kogyo Co., Ltd. Modified granulocyte-colony stimulating factor polypeptide with added carbohydrate chains
US5130143A (en) * 1988-11-04 1992-07-14 The Research Foundation Of State University Of New York Use of a low affinity-heparin fraction in conjunction with t-pa for thrombolytic therapy
US5070021A (en) * 1989-01-10 1991-12-03 Monsanto Company Method of modifying oligosaccharide structure of tissue plasminogen activator
US5089409A (en) * 1989-09-28 1992-02-18 Monsanto Company Method of increasing specific activity of t-pa
US5100778A (en) * 1989-10-03 1992-03-31 Monsanto Company Oligosaccharide sequencing
US5284558A (en) * 1990-07-27 1994-02-08 University Of Iowa Research Foundation Electrophoresis-based sequencing of oligosaccharides
US5242688A (en) * 1990-12-24 1993-09-07 Eli Lilly And Company Method of treating thromboembolic disorders by administration of diglycosylated t-pa variants

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3904470A (en) * 1973-05-02 1975-09-09 Mitsui Petrochemical Ind Method for bonding rubber to plastics
US4190708A (en) * 1978-05-24 1980-02-26 Monsanto Company Production of urokinase
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
US4335215A (en) * 1980-08-27 1982-06-15 Monsanto Company Method of growing anchorage-dependent cells
IL68561A (en) * 1982-05-05 1991-01-31 Genentech Inc Preparation of polypeptide with human tissue plasminogen activator function,processes for making it,and dna and transformed cell intermediates thereof
JPS5951220A (ja) * 1982-08-02 1984-03-24 Asahi Chem Ind Co Ltd 新規なプラスミノ−ゲン・アクチベ−タ−およびその製法ならびにこれを含有する薬剤
US4537860A (en) * 1982-12-08 1985-08-27 Monsanto Company Static cell culture maintenance system
IE56716B1 (en) * 1983-01-19 1991-11-20 Genentech Inc Method for producing human tpa and expression vectors therefor
US4550080A (en) * 1984-06-05 1985-10-29 Asahi Kasei Kogyo Kabushiki Kaisha Process for the preparation of a plasminogen activator

Also Published As

Publication number Publication date
AU604425B2 (en) 1990-12-13
NO870772D0 (no) 1987-02-25
AU6922987A (en) 1987-08-27
FI870818L (fi) 1987-08-27
KR870008025A (ko) 1987-09-23
NO870772L (no) 1987-08-27
PT84356B (pt) 1989-10-04
DK96787A (da) 1987-10-23
US4751084A (en) 1988-06-14
AU4449289A (en) 1990-03-01
NZ219398A (en) 1990-02-26
FI870818A0 (fi) 1987-02-25
KR900007084B1 (ko) 1990-09-28
AU598792B2 (en) 1990-07-05
PT84356A (en) 1987-03-01
DK96787D0 (da) 1987-02-25

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Legal Events

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FD Application lapsed

Owner name: MONSANTO COMPANY