FI873060A7 - Modifierad vävnads-plasmin-aktivator. - Google Patents

Modifierad vävnads-plasmin-aktivator. Download PDF

Info

Publication number: FI873060A7
Authority: FI; Finland
Prior art keywords: modified tissue; plasmin activator; tissue plasmin; activator; modified
Prior art date: 1986-07-11

Application number

FI873060A

Other languages

English (en)

Finnish (fi)

Other versions

FI873060L (fi

FI873060A0 (fi

Inventor

Per Bruno Wallen

Bo Anders Norrman

Bjorn Andersen Nexo

Original Assignee

Novo Nordisk As

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-07-11

Filing date

1987-07-10

Publication date

1988-01-12

1987-07-10 Application filed by Novo Nordisk As filed Critical Novo Nordisk As

1987-07-10 Publication of FI873060A0 publication Critical patent/FI873060A0/fi

1988-01-12 Publication of FI873060L publication Critical patent/FI873060L/fi

1988-01-12 Publication of FI873060A7 publication Critical patent/FI873060A7/sv

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
- C12N9/6456—Plasminogen activators
- C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
- C12Y304/21—Serine endopeptidases (3.4.21)
- C12Y304/21069—Protein C activated (3.4.21.69)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Zoology (AREA)
General Health & Medical Sciences (AREA)
Wood Science & Technology (AREA)
Genetics & Genomics (AREA)
Biomedical Technology (AREA)
Biochemistry (AREA)
Medicinal Chemistry (AREA)
General Engineering & Computer Science (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Diabetes (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Hematology (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Molecular Biology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Enzymes And Modification Thereof (AREA)
Peptides Or Proteins (AREA)

FI873060A 1986-07-11 1987-07-10 Modifierad vävnads-plasmin-aktivator. FI873060A7 (sv)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US88435786A	1986-07-11	1986-07-11

Publications (3)

Publication Number	Publication Date
FI873060A0 FI873060A0 (fi)	1987-07-10
FI873060L FI873060L (fi)	1988-01-12
FI873060A7 true FI873060A7 (sv)	1988-01-12

Family

ID=25384445

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI873060A FI873060A7 (sv)	1986-07-11	1987-07-10	Modifierad vävnads-plasmin-aktivator.

Country Status (5)

Country	Link
EP (1)	EP0253582A1 (sv)
JP (1)	JPS63119675A (sv)
DK (1)	DK345087A (sv)
FI (1)	FI873060A7 (sv)
NO (1)	NO872875L (sv)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5108909A (en) *	1985-03-22	1992-04-28	Chiron Corporation	Expression of TPA in mammalian cells
ZA869626B (en) *	1985-12-23	1987-10-28	Chiron Corp	Peptide plasminogen activators
SE8702562L (sv) *	1987-06-18	1988-12-19	Kabigen Ab	Nya fibrinolytiska enzymer
DK395288D0 (da) *	1988-07-15	1988-07-15	Novo Industri As	Proteiner
US5108901A (en) *	1988-09-02	1992-04-28	Genentech, Inc.	Tissue plasminogen activator having zymogenic or fibrin specific properties
US5714145A (en) *	1988-09-02	1998-02-03	Genentech, Inc.	Tissue plasminogen activator having zymogenic or fibrin specific properties
US5262170A (en) *	1988-09-02	1993-11-16	Genentech, Inc.	Tissue plasminogen activator having zymogenic or fibrin specific properties and substituted at amino acid positions 296-299, DNA molecules encoding them, vectors, and host cells
ES2107041T3 (es) *	1992-06-03	1997-11-16	Genentech Inc	Variantes de activador de plasminogeno tisular obtenidos por glicosilacion, que presentan propiedades terapeuticas.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GR79202B (sv) *	1982-05-05	1984-10-22	Genentech Inc
US4753879A (en) *	1984-08-27	1988-06-28	Biogen N.V.	Modified tissue plasminogen activators

1987
- 1987-07-06 DK DK345087A patent/DK345087A/da not_active Application Discontinuation
- 1987-07-10 FI FI873060A patent/FI873060A7/sv not_active Application Discontinuation
- 1987-07-10 EP EP87306099A patent/EP0253582A1/en not_active Withdrawn
- 1987-07-10 JP JP62171303A patent/JPS63119675A/ja active Pending
- 1987-07-10 NO NO872875A patent/NO872875L/no unknown

Also Published As

Publication number	Publication date
DK345087D0 (da)	1987-07-06
AU7554687A (en)	1988-01-14
EP0253582A1 (en)	1988-01-20
AU608232B2 (en)	1991-03-28
NO872875D0 (no)	1987-07-10
FI873060L (fi)	1988-01-12
DK345087A (da)	1988-01-12
NO872875L (no)	1988-01-12
FI873060A0 (fi)	1987-07-10
JPS63119675A (ja)	1988-05-24

Publication	Publication Date	Title
DE69012888D1 (de)	1994-11-03	Plasminogenaktivator.
FI870898A0 (fi)	1987-03-02	Kirurgisk reparationsanordning.
FI873700A0 (fi)	1987-08-26	Kirurgisk protes.
NO901158D0 (no)	1990-03-13	Blodtrykk-overvaakningskateter.
DE3879990D1 (de)	1993-05-13	Chirurgische agraffe.
FI891182A0 (fi)	1989-03-13	Kirurgisk hopsyningsanordning.
FI892076L (fi)	1989-05-02	Kirurgiskt faeste.
DE58906349D1 (de)	1994-01-20	Endoskop.
DE3676760D1 (de)	1991-02-14	Poly-kringle-plasminogenaktivator.
FI875020A7 (sv)	1988-05-21	Terapeutiska ämnen.
DK96787D0 (da)	1987-02-25	Human vaevs-plasminogenaktivator
NO911234L (no)	1991-03-26	Innsmekkbar aktivatorhendel.
FI831484A7 (sv)	1983-11-06	Plasminogen aktivator för mänskovävnad.
DE3763226D1 (de)	1990-07-19	Verankerung.
FI893833A7 (fi)	1990-03-01	Rekombinant aktivator foer naturliga doedarceller.
DE68901887D1 (de)	1992-07-30	Gewebedilatatoren.
NO871883L (no)	1987-11-09	Fremgangsmaate for rensing av enkelt- og dobbeltkjedet vevplasminogenaktivator.
DE68902969D1 (de)	1992-10-29	Gewebe-berieselungsloesung.
FI873060A7 (sv)	1988-01-12	Modifierad vävnads-plasmin-aktivator.
FI883943A0 (fi)	1988-08-26	Modifierade plasminogen-aktivatorer.
FI873879L (fi)	1987-09-08	Lymfocyter aktiverande polypeptider.
NO871477L (no)	1987-10-12	Fremgangsmaate for fremstilling av human plasminogenaktivator.
DE3860318D1 (de)	1990-08-23	Gewebe-schlitzgeraet.
FI881903A0 (fi)	1988-04-22	Kirurgisk slutningsanordning..
IT1227884B (it)	1991-05-14	Attivatore per osteoblasto

Legal Events

Date	Code	Title	Description
2004-08-31	FA	Application withdrawn [patent]	Owner name: NOVO NORDISK A/S