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FI862629L - Foerfarande foer framstaellning av en injicerbar loesning faerdig foer anvaendning och innehaollande en antitumoerantracyklinlykosid. - Google Patents

Foerfarande foer framstaellning av en injicerbar loesning faerdig foer anvaendning och innehaollande en antitumoerantracyklinlykosid. Download PDF

Info

Publication number
FI862629L
FI862629L FI862629A FI862629A FI862629L FI 862629 L FI862629 L FI 862629L FI 862629 A FI862629 A FI 862629A FI 862629 A FI862629 A FI 862629A FI 862629 L FI862629 L FI 862629L
Authority
FI
Finland
Prior art keywords
foer
injicerbar
faerdig
antitumoerantracyklinlykosid
loesning
Prior art date
Application number
FI862629A
Other languages
English (en)
Other versions
FI862629A0 (fi
FI86800B (fi
FI86800C (fi
Inventor
Gaetano Gatti
Diego Oldani
Giuseppe Bottoni
Carlo Confalonieri
Luciano Gambini
Ponti Roberto De
Original Assignee
Erba Farmitalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10583216&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=FI862629(L) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Erba Farmitalia filed Critical Erba Farmitalia
Publication of FI862629A0 publication Critical patent/FI862629A0/fi
Publication of FI862629L publication Critical patent/FI862629L/fi
Publication of FI86800B publication Critical patent/FI86800B/fi
Application granted granted Critical
Publication of FI86800C publication Critical patent/FI86800C/fi

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20Carbocyclic rings
    • C07H15/24Condensed ring systems having three or more rings
    • C07H15/252Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Saccharide Compounds (AREA)
FI862629A 1985-08-02 1986-06-19 Menetelmä injektoitavan, käyttövalmiin, steriilin, pyrogeenivapaan antrasykliiniglykosidiliuoksen valmistamiseksi FI86800C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858519452A GB8519452D0 (en) 1985-08-02 1985-08-02 Injectable solutions
GB8519452 1985-08-02

Publications (4)

Publication Number Publication Date
FI862629A0 FI862629A0 (fi) 1986-06-19
FI862629L true FI862629L (fi) 1987-02-03
FI86800B FI86800B (fi) 1992-07-15
FI86800C FI86800C (fi) 1999-10-28

Family

ID=10583216

Family Applications (1)

Application Number Title Priority Date Filing Date
FI862629A FI86800C (fi) 1985-08-02 1986-06-19 Menetelmä injektoitavan, käyttövalmiin, steriilin, pyrogeenivapaan antrasykliiniglykosidiliuoksen valmistamiseksi

Country Status (34)

Country Link
US (1) US4946831A (fi)
JP (1) JPH0655667B2 (fi)
KR (1) KR920001773B1 (fi)
CN (1) CN1064531C (fi)
AT (1) AT397463B (fi)
BE (1) BE905202A (fi)
BG (1) BG60425B2 (fi)
CA (1) CA1291037C (fi)
CH (2) CH690490C2 (fi)
CS (1) CS277561B6 (fi)
CY (1) CY1592A (fi)
DE (1) DE3621844C2 (fi)
DK (1) DK167557B1 (fi)
ES (1) ES8801580A1 (fi)
FI (1) FI86800C (fi)
FR (1) FR2585569B1 (fi)
GB (2) GB8519452D0 (fi)
GR (1) GR861556B (fi)
HK (1) HK93990A (fi)
HU (1) HU196123B (fi)
IE (1) IE59297B1 (fi)
IL (1) IL79129A (fi)
IT (1) IT1204906B (fi)
NL (2) NL191507C (fi)
NO (1) NO170913C (fi)
NZ (1) NZ216604A (fi)
PH (1) PH22332A (fi)
PT (1) PT82865B (fi)
RU (2) RU1837883C (fi)
SE (1) SE466383C (fi)
SG (1) SG80690G (fi)
UA (1) UA29383C2 (fi)
YU (1) YU44788B (fi)
ZA (1) ZA864792B (fi)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5124317A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.P.A. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5124318A (en) * 1985-08-02 1992-06-23 Farmitalia Carlo Erba S.R.L. Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
US5977082A (en) * 1985-08-02 1999-11-02 Pharmacia & Upjohn Company Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
CN1058391C (zh) * 1986-12-05 2000-11-15 卡洛埃尔巴意大利农业公司 已制成的可用的注射用蒽环苷类抗癌剂的溶液
FI883337L (fi) * 1987-07-16 1989-01-17 Bristol Myers Co Icke-vattenloesningar av doxorubicinhydroklorin.
FI883338A7 (fi) * 1987-07-16 1989-01-17 Bristol Myers Squibb Co Doksorubisiinihydrokloridin vesiliuoksia
DE3801178A1 (de) * 1988-01-18 1989-07-27 Hoechst Ag Stabilisierte trockenzubereitung zytostatisch wirksamer anthracyclin-antibiotika und verfahren zu ihrer herstellung
JPH02200636A (ja) * 1988-12-05 1990-08-08 Bristol Myers Squibb Co ドキソルビシン非水溶液
FI895733A7 (fi) * 1988-12-05 1990-06-06 Bristol Myers Squibb Co Doksorubisiinin vesiliuoksia
GB9200247D0 (en) * 1992-01-07 1992-02-26 Erba Carlo Spa Pharmaceutical compositions containing polymer derivative-bound anthracycline glycosides and a method for their preparation
DE19544532C2 (de) * 1995-11-29 1997-12-11 Pharma Dynamics Gmbh Verfahren zum Herstellen eines Doxorubicin-Lyophilisats
SI0848009T1 (en) * 1996-12-16 2000-12-31 Pharmachemie B.V. A process for preparing epirubicin or acid addition salts thereof from daunorubicin
US6471943B1 (en) 1996-12-30 2002-10-29 Battelle Pulmonary Therapeutics, Inc. Formulation and method for treating neoplasms by inhalation
US20090253220A1 (en) * 2003-10-28 2009-10-08 Sukanta Banerjee Absorbing Biomolecules into Gel-Shell Beads
JP2008513519A (ja) * 2005-05-11 2008-05-01 シコール インコーポレイティド 安定した凍結乾燥されたアントラサイクリングリコシド
WO2013063286A1 (en) * 2011-10-25 2013-05-02 Nektar Therapeutics Treatment of patients suffering from cancer
CN102614118B (zh) * 2012-03-15 2014-04-30 北京协和药厂 注射用盐酸表柔比星制剂的制备方法及制剂

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU33730B (en) * 1967-04-18 1978-02-28 Farmaceutici Italia Process for preparing a novel antibiotic substance and salts thereof
GB1457632A (en) * 1974-03-22 1976-12-08 Farmaceutici Italia Adriamycins
GB1500421A (en) * 1975-01-22 1978-02-08 Farmaceutici Italia Optically active anthracyclinones
US4039663A (en) * 1975-03-19 1977-08-02 Societa' Farmaceutici Italia S.P.A. Daunomycins, process for their uses and intermediates
FR2314726A1 (fr) * 1975-06-16 1977-01-14 Rhone Poulenc Ind Nouveaux derives du naphtagene, leur preparation et les compositions qui les contiennent
GB1511559A (en) * 1975-09-26 1978-05-24 Farmaceutici Italia Anthracycline glycosides
FR2397425A1 (fr) * 1977-07-11 1979-02-09 Rhone Poulenc Ind Nouveaux derives de la daunorubicine, leur preparation et les compositions qui les contiennent
DE2738656A1 (de) * 1977-08-26 1979-03-08 Microbial Chem Res Found Anthracyclinglycoside, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
GB2007645B (en) * 1977-10-17 1982-05-12 Stanford Res Inst Int Benzyl anthracyclines and pharmaceutical compositions containing them
US4177264A (en) * 1977-10-17 1979-12-04 Sri International N-benzyl anthracyclines
FR2430425A1 (fr) * 1978-07-07 1980-02-01 Rhone Poulenc Ind Nouveaux derives de la daunorubicine, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2433027A1 (fr) * 1978-08-08 1980-03-07 Rhone Poulenc Ind Nouveau procede de preparation de derives de la doxorubicine
US4325947A (en) * 1981-05-12 1982-04-20 Farmitalia Carlo Erba S.P.A. 4-Demethoxy-4'-deoxydoxorubicin
US4438105A (en) * 1982-04-19 1984-03-20 Farmaitalia Carlo Erba S.P.A 4'-Iododerivatives of anthracycline glycosides
US4464529A (en) * 1982-07-20 1984-08-07 Sri International Analogues of morpholinyl daunorubicin and morpholinyl doxorubicin
JPS6092212A (ja) * 1983-10-26 1985-05-23 Kyowa Hakko Kogyo Co Ltd ドキソルビシン塩の製剤
CN1058391C (zh) * 1986-12-05 2000-11-15 卡洛埃尔巴意大利农业公司 已制成的可用的注射用蒽环苷类抗癌剂的溶液

Also Published As

Publication number Publication date
GR861556B (en) 1986-10-17
JPH0655667B2 (ja) 1994-07-27
HK93990A (en) 1990-11-23
NL300011I1 (nl) 2000-10-02
NO170913C (no) 2003-10-10
AU5885886A (en) 1987-02-12
FR2585569B1 (fr) 1990-01-19
CY1592A (en) 1992-04-03
DK167557B1 (da) 1993-11-22
KR920001773B1 (ko) 1992-03-02
SE8602743L (sv) 1987-02-03
CN1064531C (zh) 2001-04-18
KR870001828A (ko) 1987-03-28
CH668911A5 (de) 1989-02-15
GB8614800D0 (en) 1986-07-23
PH22332A (en) 1988-07-29
FR2585569A1 (fr) 1987-02-06
FI862629A0 (fi) 1986-06-19
BG60425B2 (bg) 1995-03-31
NO862587L (no) 1987-02-03
DE3621844A1 (de) 1987-03-05
DK306286A (da) 1987-02-03
NO170913B (no) 1992-09-21
IE59297B1 (en) 1994-02-09
PT82865A (en) 1986-07-01
IT8620917A0 (it) 1986-06-26
SE8602743D0 (sv) 1986-06-19
YU103586A (en) 1988-04-30
IE861598L (en) 1987-02-02
CS470886A3 (en) 1992-11-18
IL79129A0 (en) 1986-09-30
DK306286D0 (da) 1986-06-27
BE905202A (fr) 1987-02-02
SE466383B (sv) 1992-02-10
GB2178311B (en) 1989-10-11
PT82865B (pt) 1989-01-17
GB8519452D0 (en) 1985-09-11
HUT42326A (en) 1987-07-28
YU44788B (en) 1991-02-28
RU2110263C1 (ru) 1998-05-10
ZA864792B (en) 1988-02-24
US4946831A (en) 1990-08-07
RU1837883C (ru) 1993-08-30
CA1291037C (en) 1991-10-22
AU598197B2 (en) 1990-06-21
NL191507B (nl) 1995-04-18
NZ216604A (en) 1989-10-27
IL79129A (en) 1992-03-29
ES8801580A1 (es) 1988-02-16
AT397463B (de) 1994-04-25
DE3621844C2 (de) 1994-02-17
HU196123B (en) 1988-10-28
NO862587D0 (no) 1986-06-26
SG80690G (en) 1990-11-23
FI86800B (fi) 1992-07-15
SE466383C (sv) 1996-02-19
NL191507C (nl) 2000-02-16
NL8601698A (nl) 1987-03-02
CS277561B6 (en) 1993-03-17
JPS6248629A (ja) 1987-03-03
CH690490C2 (de) 2000-09-29
ATA176886A (de) 1993-09-15
IT1204906B (it) 1989-03-10
FI86800C (fi) 1999-10-28
CH668911C1 (de) 2000-05-31
ES556291A0 (es) 1988-02-16
UA29383C2 (uk) 2000-11-15
GB2178311A (en) 1987-02-11
CN86104283A (zh) 1987-01-28

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Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: PHARMACIA & UPJOHN S.P.A.

GB Transfer or assigment of application

Owner name: PHARMACIA & UPJOHN S.P.A.

SPCG Supplementary protection certificate granted

Spc suppl protection certif: L164

Extension date: 20110618

FG Patent granted

Owner name: PHARMACIA ITALIA S.P.A.

MA Patent expired
PC Transfer of assignment of patent

Owner name: PFIZER ITALIA S.R.L.

Free format text: PFIZER ITALIA S.R.L.