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FI865187L - Menetelmä eukaryoottisen painolastiosan sisältävien fuusioproteiinien valmistamiseksi ja menetelmässä käyttökelpoisia tuotteita - Google Patents

Menetelmä eukaryoottisen painolastiosan sisältävien fuusioproteiinien valmistamiseksi ja menetelmässä käyttökelpoisia tuotteita Download PDF

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Publication number
FI865187L
FI865187L FI865187A FI865187A FI865187L FI 865187 L FI865187 L FI 865187L FI 865187 A FI865187 A FI 865187A FI 865187 A FI865187 A FI 865187A FI 865187 L FI865187 L FI 865187L
Authority
FI
Finland
Prior art keywords
eukaryotic
fusion proteins
proteins containing
products useful
preparing fusion
Prior art date
Application number
FI865187A
Other languages
English (en)
Swedish (sv)
Other versions
FI865187A0 (fi
FI93734B (fi
FI93734C (fi
Inventor
Paul Habermann
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI865187A0 publication Critical patent/FI865187A0/fi
Publication of FI865187L publication Critical patent/FI865187L/fi
Publication of FI93734B publication Critical patent/FI93734B/fi
Application granted granted Critical
Publication of FI93734C publication Critical patent/FI93734C/fi

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/815Protease inhibitors from leeches, e.g. hirudin, eglin
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/55IL-2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/70Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Plant Pathology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI865187A 1985-12-21 1986-12-18 Menetelmä eukaryoottisen painolastiosan sisältävien fuusioproteiinien valmistamiseksi ja menetelmässä käyttökelpoisia tuotteita FI93734C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE3545565 1985-12-21
DE3545565 1985-12-21
DE3636903 1986-10-30
DE19863636903 DE3636903A1 (de) 1985-12-21 1986-10-30 Fusionsproteine mit eukaryotischem ballastanteil

Publications (4)

Publication Number Publication Date
FI865187A0 FI865187A0 (fi) 1986-12-18
FI865187L true FI865187L (fi) 1987-06-22
FI93734B FI93734B (fi) 1995-02-15
FI93734C FI93734C (fi) 1995-05-26

Family

ID=25839208

Family Applications (1)

Application Number Title Priority Date Filing Date
FI865187A FI93734C (fi) 1985-12-21 1986-12-18 Menetelmä eukaryoottisen painolastiosan sisältävien fuusioproteiinien valmistamiseksi ja menetelmässä käyttökelpoisia tuotteita

Country Status (16)

Country Link
EP (1) EP0229998B1 (fi)
JP (2) JP2553058B2 (fi)
KR (1) KR950000301B1 (fi)
AT (1) ATE78296T1 (fi)
AU (1) AU599943B2 (fi)
CA (1) CA1339894C (fi)
DE (1) DE3636903A1 (fi)
DK (1) DK168823B1 (fi)
ES (1) ES2033678T3 (fi)
FI (1) FI93734C (fi)
GR (1) GR3005985T3 (fi)
HU (1) HU209747B (fi)
IE (1) IE58935B1 (fi)
IL (1) IL81018A (fi)
NO (1) NO175003C (fi)
PT (1) PT83973B (fi)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3545568A1 (de) * 1985-12-21 1987-07-16 Hoechst Ag Gm-csf-protein, seine derivate, herstellung solcher proteine und ihre verwendung
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
FR2643646B1 (fr) * 1989-02-27 1993-09-17 Pasteur Institut Expression de sequences de nucleotides codant pour des vesicules a gaz
CU22222A1 (es) * 1989-08-03 1995-01-31 Cigb Procedimiento para la expresion de proteinas heterologicas producidas de forma fusionada en escherichia coli, su uso, vectores de expresion y cepas recombinantes
DE3942580A1 (de) * 1989-12-22 1991-06-27 Basf Ag Verfahren zur herstellung von hirudin
DE4105480A1 (de) * 1991-02-21 1992-08-27 Boehringer Mannheim Gmbh Verbesserte aktivierung von rekombinanten proteinen
ATE264871T1 (de) 1996-07-26 2004-05-15 Aventis Pharma Gmbh Insulinderivate mit erhöhter zinkbindung
DE19825447A1 (de) 1998-06-06 1999-12-09 Hoechst Marion Roussel De Gmbh Neue Insulinanaloga mit erhöhter Zinkbildung
DE102006031955A1 (de) 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Verfahren zur Herstellung von Insulinanaloga mit dibasischem B-Kettenende
DE102006031962A1 (de) 2006-07-11 2008-01-17 Sanofi-Aventis Deutschland Gmbh Amidiertes Insulin Glargin
PT2349324T (pt) 2008-10-17 2017-12-06 Sanofi Aventis Deutschland Combinação de uma insulina e de um agonista do glp-1
WO2011058083A1 (de) 2009-11-13 2011-05-19 Sanofi-Aventis Deutschland Gmbh Pharmazeutische zusammensetzung umfassend einen glp-1-agonisten, ein insulin und methionin
SG10201500871TA (en) 2009-11-13 2015-04-29 Sanofi Aventis Deutschland Pharmaceutical composition comprising a glp-1 agonist and methionine
RS55378B1 (sr) 2010-08-30 2017-03-31 Sanofi Aventis Deutschland Upotreba ave0010 za proizvodnju leka za tretman diabetes mellitus tipa 2
US9821032B2 (en) 2011-05-13 2017-11-21 Sanofi-Aventis Deutschland Gmbh Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
HRP20151068T1 (hr) 2011-08-29 2016-01-01 Sanofi-Aventis Deutschland Gmbh Farmaceutska kombinacija za upotrebu za glikemijsku kontrolu kod pacijenata s dijabetesom tipa 2
AR087744A1 (es) 2011-09-01 2014-04-16 Sanofi Aventis Deutschland Composicion farmaceutica para uso en el tratamiento de una enfermedad neurodegenerativa
TWI758239B (zh) 2014-12-12 2022-03-21 德商賽諾菲阿凡提斯德意志有限公司 甘精胰島素/利司那肽固定比率配製劑
TWI748945B (zh) 2015-03-13 2021-12-11 德商賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患治療
TW201705975A (zh) 2015-03-18 2017-02-16 賽諾菲阿凡提斯德意志有限公司 第2型糖尿病病患之治療
KR20200080748A (ko) 2018-12-27 2020-07-07 주식회사 폴루스 음이온 교환 크로마토그래피를 이용한 인슐린 전구체의 정제방법
KR20200080747A (ko) 2018-12-27 2020-07-07 주식회사 폴루스 인슐린 전구체의 인슐린 효소 전환용 조성물 및 이를 이용하여 인슐린 전구체를 인슐린으로 전환하는 방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK108685A (da) * 1984-03-19 1985-09-20 Fujisawa Pharmaceutical Co Vaekstfaktor i
EP0158198A1 (en) * 1984-03-29 1985-10-16 Takeda Chemical Industries, Ltd. DNA and use thereof
GB8412517D0 (en) * 1984-05-16 1984-06-20 Nagai K Recombinant fusion proteins

Also Published As

Publication number Publication date
NO865192D0 (no) 1986-12-19
AU6676086A (en) 1987-06-25
JP2774260B2 (ja) 1998-07-09
NO175003C (no) 1994-08-17
ATE78296T1 (de) 1992-08-15
EP0229998A2 (de) 1987-07-29
DK168823B1 (da) 1994-06-20
NO865192L (no) 1987-06-22
JPS62167799A (ja) 1987-07-24
KR870006187A (ko) 1987-07-09
EP0229998A3 (en) 1988-08-03
IL81018A0 (en) 1987-03-31
CA1339894C (en) 1998-06-02
KR950000301B1 (ko) 1995-01-13
DE3636903A1 (de) 1987-07-02
IE58935B1 (en) 1993-12-01
IL81018A (en) 1992-03-29
JP2553058B2 (ja) 1996-11-13
DK619186D0 (da) 1986-12-19
PT83973A (de) 1987-01-01
ES2033678T3 (es) 1993-04-01
GR3005985T3 (fi) 1993-06-07
PT83973B (pt) 1989-07-31
HUT44614A (en) 1988-03-28
NO175003B (no) 1994-05-09
DK619186A (da) 1987-06-22
JPH08187089A (ja) 1996-07-23
FI865187A0 (fi) 1986-12-18
HU209747B (en) 1994-10-28
FI93734B (fi) 1995-02-15
AU599943B2 (en) 1990-08-02
EP0229998B1 (de) 1992-07-15
IE863334L (en) 1987-06-21
FI93734C (fi) 1995-05-26

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BB Publication of examined application
FG Patent granted

Owner name: HOECHST AKTIENGESELLSCHAFT

MA Patent expired