FI834771L - Kristalliserade kefem-syraadditionssalter och foerfarande foer deras framstaellning. - Google Patents

Kristalliserade kefem-syraadditionssalter och foerfarande foer deras framstaellning. Download PDF

Info

Publication number: FI834771L
Authority: FI; Finland
Prior art keywords: kristalserade; kefem; syraadditionssalter; foerfarande foer; och foerfarande
Prior art date: 1982-12-28

Application number

FI834771A

Other languages

English (en)

Other versions

FI76094C (fi

FI76094B (fi

FI834771A0 (fi

Inventor

Walter Dyrckheimer

Rudolf Lattrell

Original Assignee

Hoechst Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-12-28

Filing date

1983-12-23

Publication date

1984-06-29

1983-12-23 Application filed by Hoechst Ag filed Critical Hoechst Ag

1983-12-23 Publication of FI834771A0 publication Critical patent/FI834771A0/fi

1984-06-29 Publication of FI834771L publication Critical patent/FI834771L/fi

1988-05-31 Application granted granted Critical

1988-05-31 Publication of FI76094B publication Critical patent/FI76094B/fi

1988-09-09 Publication of FI76094C publication Critical patent/FI76094C/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cephalosporin Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

FI834771A 1982-12-28 1983-12-23 Foerfarande foer framstaellning av terapeutiskt anvaendbara kristallina 7-(2-(2-aminotiazol-4-yl)-2- syn-metoxiiminoacetamido)-3-((2,3-cyklopenteno-1-pyridino)-metyl)- cef-3-em-4-karboxylat-syraadditionssalter. FI76094C (fi)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE19823248281 DE3248281A1 (de)	1982-12-28	1982-12-28	Kristalisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE3248281		1982-12-28

Publications (4)

Publication Number	Publication Date
FI834771A0 FI834771A0 (fi)	1983-12-23
FI834771L true FI834771L (fi)	1984-06-29
FI76094B FI76094B (fi)	1988-05-31
FI76094C FI76094C (fi)	1988-09-09

Family

ID=6181953

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI834771A FI76094C (fi)	1982-12-28	1983-12-23	Foerfarande foer framstaellning av terapeutiskt anvaendbara kristallina 7-(2-(2-aminotiazol-4-yl)-2- syn-metoxiiminoacetamido)-3-((2,3-cyklopenteno-1-pyridino)-metyl)- cef-3-em-4-karboxylat-syraadditionssalter.

Country Status (28)

Country	Link
US (1)	US4609653A (fi)
EP (1)	EP0112550B1 (fi)
JP (1)	JPH0723382B2 (fi)
KR (1)	KR910000420B1 (fi)
AR (1)	AR245133A1 (fi)
AT (1)	ATE50261T1 (fi)
AU (1)	AU562714B2 (fi)
CA (1)	CA1235690A (fi)
CS (2)	CS241070B2 (fi)
DD (1)	DD215552A5 (fi)
DE (2)	DE3248281A1 (fi)
DK (1)	DK166211C (fi)
DZ (1)	DZ592A1 (fi)
ES (1)	ES8407495A1 (fi)
FI (1)	FI76094C (fi)
GR (1)	GR79444B (fi)
HU (1)	HU191385B (fi)
IE (1)	IE56488B1 (fi)
IL (1)	IL70544A (fi)
MA (1)	MA19990A1 (fi)
NO (1)	NO834824L (fi)
NZ (1)	NZ206704A (fi)
OA (1)	OA07622A (fi)
PH (1)	PH19269A (fi)
PT (1)	PT77896B (fi)
SU (1)	SU1292668A3 (fi)
YU (1)	YU43200B (fi)
ZA (1)	ZA839593B (fi)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3118732A1 (de) *	1981-05-12	1982-12-02	Hoechst Ag, 6000 Frankfurt	Cephalosporinderivate und verfahren zu ihrer herstellung
JPS60142987A (ja) *	1983-12-29	1985-07-29	Mochida Pharmaceut Co Ltd	セフアロスポリン誘導体
DE150507T1 (de) *	1983-12-29	1987-02-26	Mochida Pharmaceutical Co., Ltd., Tokio/Tokyo	Cephalosporinverbindungen, verfahren zu ihrer herstellung und pharmazeutishe praeparate.
JPS60169486A (ja) *	1984-02-10	1985-09-02	Yamanouchi Pharmaceut Co Ltd	７−アミノ−３−置換メチル−３−セフエム−４−カルボン酸およびその低級アルキルシリル誘導体の製造法
JPH0649707B2 (ja) *	1985-03-01	1994-06-29	第一製薬株式会社	３−ピリジニウムメチルセフエム誘導体
US4840945A (en) *	1985-04-01	1989-06-20	Mochida Pharmaceutical Co., Ltd.	Cephalosporin derivatives
US5244891A (en) *	1985-08-05	1993-09-14	Bristol-Myers Squibb Company	Injectable compositions of cefepime dihydrochloride hydrate
JPS63132893A (ja) *	1986-11-25	1988-06-04	Mochida Pharmaceut Co Ltd	新規セフアロスポリン誘導体、その製法およびそれらを有効成分とする抗菌剤
US4880798A (en) *	1986-11-25	1989-11-14	Mochida Pharmaceutical Co., Ltd.	Cephalosporin derivatives
DE3706020A1 (de) *	1987-02-25	1988-09-08	Hoechst Ag	Kristallisierte cephem-saeureadditionssalze und verfahren zu ihrer herstellung
DE4440141A1 (de) *	1994-11-10	1996-05-15	Hoechst Ag	Neue kristalline Cephem-Säureadditionssalze und Verfahren zu ihrer Herstellung
TW526202B (en)	1998-11-27	2003-04-01	Shionogi & Amp Co	Broad spectrum cephem having benzo[4,5-b]pyridium methyl group of antibiotic activity
DE60205882D1 (de) *	2001-04-23	2005-10-06	Shionogi & Co	Sulfat von cephemverbindung
AU2003275682A1 (en) *	2002-10-29	2004-05-25	Shionogi And Co., Ltd.	Crystal of inorganic acid salt of cephem compound
CN101172982B (zh) *	2006-11-03	2011-06-08	河北凯盛医药科技有限公司	一种硫酸头孢匹罗的制备方法
WO2008056221A2 (en) *	2006-11-06	2008-05-15	Orchid Chemicals & Pharmaceuticals Limited	Crystalline sulfate salt of cephalosporin antibiotic
CN101104621A (zh) *	2007-05-08	2008-01-16	深圳信立泰药业股份有限公司	制备高纯度硫酸头孢匹罗的工艺
CN101284840B (zh) *	2008-05-29	2012-07-04	管小明	硫酸头孢匹罗的合成方法
CN103044455B (zh) *	2011-10-17	2015-04-01	苏州中联化学制药有限公司	硫酸头孢匹罗混粉的返工方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS523091A (en) *	1975-06-23	1977-01-11	Takeda Chem Ind Ltd	A prcess for preparing cephalosporins
DE3019838A1 (de) *	1979-05-25	1980-12-04	Glaxo Group Ltd	Zwischenprodukte zur verwendung bei der herstellung von cephalosporin-antibiotika
AU540382B2 (en) *	1979-10-02	1984-11-15	Glaxo Group Limited	7(2-(2-aminothiazol-4-yl)-2-(2-carboxy prop-2-oxyimino) acetamido)-3-(1-pyridiniummethyl) ceph-3-em-4-carboxylate
ES8306160A1 (es) *	1981-04-03	1983-05-01	Fujisawa Pharmaceutical Co	"procedimiento para preparar un nuevo compuesto de cefem".
DE3118732A1 (de) *	1981-05-12	1982-12-02	Hoechst Ag, 6000 Frankfurt	Cephalosporinderivate und verfahren zu ihrer herstellung

1982
- 1982-12-28 DE DE19823248281 patent/DE3248281A1/de not_active Withdrawn
1983
- 1983-12-21 AT AT83112862T patent/ATE50261T1/de not_active IP Right Cessation
- 1983-12-21 DE DE8383112862T patent/DE3381201D1/de not_active Expired - Lifetime
- 1983-12-21 HU HU834391A patent/HU191385B/hu unknown
- 1983-12-21 EP EP83112862A patent/EP0112550B1/de not_active Expired - Lifetime
- 1983-12-22 NZ NZ206704A patent/NZ206704A/xx unknown
- 1983-12-22 IE IE3045/83A patent/IE56488B1/en not_active IP Right Cessation
- 1983-12-23 AU AU22893/83A patent/AU562714B2/en not_active Expired
- 1983-12-23 CA CA000444281A patent/CA1235690A/en not_active Expired
- 1983-12-23 FI FI834771A patent/FI76094C/fi not_active IP Right Cessation
- 1983-12-26 IL IL70544A patent/IL70544A/xx not_active IP Right Cessation
- 1983-12-26 YU YU2511/83A patent/YU43200B/xx unknown
- 1983-12-26 KR KR1019830006181A patent/KR910000420B1/ko not_active Expired
- 1983-12-26 SU SU833680600A patent/SU1292668A3/ru active
- 1983-12-26 ES ES528401A patent/ES8407495A1/es not_active Expired
- 1983-12-26 AR AR83295233A patent/AR245133A1/es active
- 1983-12-27 ZA ZA839593A patent/ZA839593B/xx unknown
- 1983-12-27 PT PT77896A patent/PT77896B/pt unknown
- 1983-12-27 MA MA20211A patent/MA19990A1/fr unknown
- 1983-12-27 CS CS839974A patent/CS241070B2/cs unknown
- 1983-12-27 DD DD83258690A patent/DD215552A5/de unknown
- 1983-12-27 US US06/565,867 patent/US4609653A/en not_active Expired - Lifetime
- 1983-12-27 PH PH30034A patent/PH19269A/en unknown
- 1983-12-27 DK DK600183A patent/DK166211C/da not_active IP Right Cessation
- 1983-12-27 GR GR73352A patent/GR79444B/el unknown
- 1983-12-27 NO NO834824A patent/NO834824L/no unknown
- 1983-12-28 DZ DZ837035A patent/DZ592A1/fr active
- 1983-12-28 JP JP58252285A patent/JPH0723382B2/ja not_active Expired - Lifetime
- 1983-12-28 OA OA58195A patent/OA07622A/xx unknown
1991
- 1991-12-30 CS CS914157A patent/CS415791A3/cs unknown

Also Published As

Publication number	Publication date
ES528401A0 (es)	1984-09-16
EP0112550A2 (de)	1984-07-04
DK166211C (da)	1993-08-16
DK166211B (da)	1993-03-22
IL70544A0 (en)	1984-03-30
FI76094C (fi)	1988-09-09
YU43200B (en)	1989-04-30
EP0112550A3 (en)	1985-09-18
KR840007016A (ko)	1984-12-04
NO834824L (no)	1984-06-29
PH19269A (en)	1986-02-21
AR245133A1 (es)	1993-12-30
JPS59130888A (ja)	1984-07-27
CS997483A2 (en)	1985-07-16
HUT34211A (en)	1985-02-28
DE3381201D1 (de)	1990-03-15
NZ206704A (en)	1986-04-11
CA1235690A (en)	1988-04-26
AU2289383A (en)	1984-07-05
ATE50261T1 (de)	1990-02-15
DE3248281A1 (de)	1984-06-28
GR79444B (fi)	1984-10-30
ES8407495A1 (es)	1984-09-16
PT77896B (de)	1986-04-21
HU191385B (en)	1987-02-27
MA19990A1 (fr)	1984-07-01
FI76094B (fi)	1988-05-31
DK600183A (da)	1984-06-29
US4609653A (en)	1986-09-02
DD215552A5 (de)	1984-11-14
CS415791A3 (en)	1992-07-15
IL70544A (en)	1987-01-30
IE56488B1 (en)	1991-08-14
KR910000420B1 (ko)	1991-01-25
PT77896A (de)	1984-01-01
DK600183D0 (da)	1983-12-27
ZA839593B (en)	1984-08-29
SU1292668A3 (ru)	1987-02-23
AU562714B2 (en)	1987-06-18
JPH0723382B2 (ja)	1995-03-15
EP0112550B1 (de)	1990-02-07
OA07622A (fr)	1985-03-31
DZ592A1 (fr)	2004-09-13
FI834771A0 (fi)	1983-12-23
IE833045L (en)	1984-06-28
CS241070B2 (en)	1986-03-13
YU251183A (en)	1986-06-30

Publication	Publication Date	Title
FI842601A0 (fi)	1984-06-28	Utdelningsanordning och uppteckningsapparat.
FI834430L (fi)	1984-06-08	Haorfaergningsfoerfarande och faergningskompositionsfoerpackning.
FI832997A7 (fi)	1983-08-22	Vattenloesliga sampolymerer, deras framstaellning och anvaendning
FI830752L (fi)	1983-09-09	Karboxialkyldipeptider, foerfaranden foer deras framstaellning och farmaceutiska blandningar innehaollande dessa
FI831591A0 (fi)	1983-05-09	Azolylmetyloxiraner, deras framstaellningsfoerfarande och dessa innehaollande fungicider
FI843299L (fi)	1984-08-21	Tuggummikomposition och soetningsfoerfarande.
FI830378L (fi)	1983-08-07	Pyrazoloxaziner, -tiaziner, -kinoliner, foerfarande foer deras framstaellning och deras anvaendninglaekemedel
FI834137A7 (fi)	1984-05-17	Bensodiazepinreceptoraktiva foereningar och foerfarande foer deras framstaellning.
FI833398A0 (fi)	1983-09-22	Termiticidala atraktantfoereningar, kompositioner och foerfarande foer deras anvaendning
FI834888A0 (fi)	1983-12-30	Gonadoliberinderivat, foerfarande foer deras framstaellning och farmaceutiska och veterinaermedicinblandningar framstaellda daerav
FI824126L (fi)	1984-05-31	Foerfarande i laonghaolbergborrning och borrstaongsystem.
FI840967L (fi)	1984-03-09	Modifierat polyisocyanuratskum och framstaellningsfoerfarande.
FI832930L (fi)	1984-02-17	Aptitreducerande trifluormetylfenyltetrahydropyridiner, foerfarande foer deras framstaellning och farmaceutiska kompositioner
FI834771L (fi)	1984-06-29	Kristalliserade kefem-syraadditionssalter och foerfarande foer deras framstaellning.
FI842376A0 (fi)	1984-06-12	Monoskopisk och stereoskopisk televisionsapparat.
FI834711A7 (fi)	1984-06-24	Kefalosporinderivat och deras framstaellningsfoerfarande.
FI834710A7 (fi)	1984-06-24	Kefalosporinderivat och foerfarande foer deras framstaellning.
FI831790A0 (fi)	1983-05-20	Piperazinderivat, deras framstaellning och dessa innehaollande farmaceutiska foereningar
FI833647A7 (fi)	1984-04-08	Fenyl-indenderivat, deras syraadditionssalt och foerfarande foer deras framstaellning
FI834041L (fi)	1984-05-07	Bismaleimid innehaollande, vaermehaerdbara kompositioner och polymerer
FI830297A0 (fi)	1983-01-27	Benzotiennylallylaminer, foerfarande foer deras producering och deras anvaendning saosom laekemedel
FI831367A0 (fi)	1983-04-21	Pleuromutillinderivat, deras framstaellningsfoerfarande och farmaceutiska anvaendning
FI834112L (fi)	1984-05-13	Isoindolderivat, deras framstaellning och anvaendning
FI840477L (fi)	1984-02-06	Foerfarande och styrsanordning foer en hydraulisk pulsgenerator.
FI833292L (fi)	1984-03-26	Piperidinderivat, deras framstaellning och anvaendning

Legal Events

Date	Code	Title	Description
2004-08-31	MA	Patent expired	Owner name: AVENTIS PHARMA DEUTSCHLAND GMBH