FI824443L - 2-/4-/(4,4-dialkyl-2,6-piperidindion-1-yl)-butyl/-1-piperazinyl/pyrimidiner - Google Patents
2-/4-/(4,4-dialkyl-2,6-piperidindion-1-yl)-butyl/-1-piperazinyl/pyrimidinerInfo
- Publication number
- FI824443L FI824443L FI824443A FI824443A FI824443L FI 824443 L FI824443 L FI 824443L FI 824443 A FI824443 A FI 824443A FI 824443 A FI824443 A FI 824443A FI 824443 L FI824443 L FI 824443L
- Authority
- FI
- Finland
- Prior art keywords
- piperidindion
- pyrimidines
- piperazinyl
- dialkyl
- butyl
- Prior art date
Links
- 150000003230 pyrimidines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C55/00—Saturated compounds having more than one carboxyl group bound to acyclic carbon atoms
- C07C55/02—Dicarboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/86—Oxygen atoms
- C07D211/88—Oxygen atoms attached in positions 2 and 6, e.g. glutarimide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/84—Nitriles
- C07D213/85—Nitriles in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Anesthesiology (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/334,689 US4361565A (en) | 1981-12-28 | 1981-12-28 | 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyridines |
| US33468981 | 1981-12-28 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| FI824443A0 FI824443A0 (fi) | 1982-12-23 |
| FI824443L true FI824443L (fi) | 1983-06-29 |
| FI70892B FI70892B (fi) | 1986-07-18 |
| FI70892C FI70892C (fi) | 1986-10-27 |
Family
ID=23308356
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI824443A FI70892C (fi) | 1981-12-28 | 1982-12-23 | Foerfarande foer framstaellning av nya terapeutiskt anvaendbara 2-(4-/(4,4-dialkyl-2,6-piperidindion-1-yl) butyl/-1-piperazinyl)pyridiner |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US4361565A (fi) |
| JP (1) | JPS58118583A (fi) |
| KR (1) | KR880002011B1 (fi) |
| AT (1) | AT380880B (fi) |
| AU (1) | AU560667B2 (fi) |
| BE (1) | BE895505A (fi) |
| CA (1) | CA1237722A (fi) |
| CH (1) | CH653682A5 (fi) |
| CY (1) | CY1378A (fi) |
| DE (1) | DE3248138A1 (fi) |
| DK (1) | DK162284C (fi) |
| ES (1) | ES518511A0 (fi) |
| FI (1) | FI70892C (fi) |
| FR (1) | FR2518994B1 (fi) |
| GB (1) | GB2114121B (fi) |
| GR (1) | GR77101B (fi) |
| HK (1) | HK5188A (fi) |
| HU (1) | HU190827B (fi) |
| IE (1) | IE54620B1 (fi) |
| IT (1) | IT1158040B (fi) |
| KE (1) | KE3714A (fi) |
| LU (1) | LU84562A1 (fi) |
| NL (1) | NL8204974A (fi) |
| PT (1) | PT76037B (fi) |
| SE (1) | SE449748B (fi) |
| SG (1) | SG29687G (fi) |
| ZA (1) | ZA828546B (fi) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AT387221B (de) * | 1980-09-08 | 1988-12-27 | Bristol Myers Co | Verfahren zur herstellung des neuen |
| AT387773B (de) * | 1983-09-12 | 1989-03-10 | Bristol Myers Co | Verfahren zur herstellung von 1-heteroaryl-4-((2,5-pyrrolidindion-1-yl)aklyl) iperazin-derivaten |
| US4524206A (en) * | 1983-09-12 | 1985-06-18 | Mead Johnson & Company | 1-Heteroaryl-4-(2,5-pyrrolidinedion-1-yl)alkyl)piperazine derivatives |
| US4619930A (en) * | 1985-01-16 | 1986-10-28 | Bristol-Myers Company | Antipsychotic cyclic imide derivatives of 2-(4-butylpiperazin-1-yl)pyridines, compositions and use |
| CA1278792C (en) * | 1985-05-06 | 1991-01-08 | Joseph P. Yevich | Antipsychotic fused-ring pyridinylpiperazine derivatives |
| US4677104A (en) * | 1985-05-06 | 1987-06-30 | Bristol-Myers Company | Antipsychotic fused-ring pyridinylpiperazine derivatives |
| US4757073A (en) * | 1986-09-30 | 1988-07-12 | Bristol-Myers Company | Antipsychotic cyclic imide derivatives of 2-(4-butylipiperazin-1-yl) pyridines, compositions and use |
| WO1989004311A1 (en) * | 1987-11-12 | 1989-05-18 | American Home Products Corporation | Polycyclicamines with psychotropic activity |
| US4855430A (en) * | 1987-11-12 | 1989-08-08 | American Home Products Corporation | Polycyclicamine with psychotropic activity |
| US4880930A (en) * | 1987-11-30 | 1989-11-14 | New James S | Psychotropic acyclic amide derivatives |
| US5001130A (en) * | 1988-02-18 | 1991-03-19 | Bristol-Myers Company | Psychotropic heterobicycloalkylpiperazine derivatives |
| US5116970A (en) * | 1988-02-18 | 1992-05-26 | New James S | Psychotropic heterobicycloalkylpiperazine derivatives: 2. fused pyridazinones |
| US5098904A (en) * | 1990-06-27 | 1992-03-24 | Bristol-Myers Squibb Company | Cerebral function enhancing pyrimidinyl derivatives |
| ZA918221B (en) * | 1990-10-23 | 1992-06-24 | Akzo Nv | 4-(4-or 6-(trifluoromethyl-2-pyridinyl))-1-piperazinyl-alkyl substituted lactams |
| JPH06504279A (ja) * | 1990-12-24 | 1994-05-19 | メレルダウファーマス−ティカルズ インコーポレイテッド | 欝病及び躁病の治療におけるある種のグルタルイミド誘導体の用途 |
| SE9201138D0 (sv) * | 1992-04-09 | 1992-04-09 | Astra Ab | Novel phthalimidoalkylpiperazines |
| KR100581199B1 (ko) | 1998-06-19 | 2006-05-17 | 카이론 코포레이션 | 글리코겐 신타제 키나제 3의 억제제 |
| US7045519B2 (en) * | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| PL2159226T3 (pl) * | 2007-03-29 | 2017-02-28 | Joint-Stock Company "Obninsk Chemical Pharmaceutical Company" | Środek antyhistaminowy i antyalergiczny oraz sposób jego wytwarzania |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3398151A (en) * | 1966-02-01 | 1968-08-20 | Mead Johnson & Co | Azaspirodecanediones and azaspiroundecanediones |
| BE759371A (fr) * | 1969-11-24 | 1971-05-24 | Bristol Myers Co | Azaspirodecanediones heterocycliques et procedes pour leur preparation |
| US3976776A (en) * | 1972-12-06 | 1976-08-24 | Mead Johnson & Company | Tranquilizer process employing N-(heteroarcyclic)piperazinylalkylazaspiroalkanediones |
| US4182763A (en) * | 1978-05-22 | 1980-01-08 | Mead Johnson & Company | Buspirone anti-anxiety method |
| AU521110B2 (en) * | 1978-06-20 | 1982-03-18 | Synthelabo | Phenylpiperazine derivatives |
| US4305944A (en) * | 1980-09-08 | 1981-12-15 | Mead Johnson & Company | N-[(4-[3-cyano substituted pyridyl]piperazino)alkyl]-azaspirodecanediones |
-
1981
- 1981-12-28 US US06/334,689 patent/US4361565A/en not_active Expired - Fee Related
-
1982
- 1982-11-19 ZA ZA828546A patent/ZA828546B/xx unknown
- 1982-11-22 CA CA000416080A patent/CA1237722A/en not_active Expired
- 1982-12-02 AU AU91084/82A patent/AU560667B2/en not_active Ceased
- 1982-12-03 KR KR8205431A patent/KR880002011B1/ko not_active Expired
- 1982-12-08 GR GR70020A patent/GR77101B/el unknown
- 1982-12-22 IT IT49720/82A patent/IT1158040B/it active
- 1982-12-23 ES ES518511A patent/ES518511A0/es active Granted
- 1982-12-23 IE IE3068/82A patent/IE54620B1/en not_active IP Right Cessation
- 1982-12-23 FI FI824443A patent/FI70892C/fi not_active IP Right Cessation
- 1982-12-23 NL NL8204974A patent/NL8204974A/nl unknown
- 1982-12-23 DK DK573282A patent/DK162284C/da active
- 1982-12-23 JP JP57225099A patent/JPS58118583A/ja active Granted
- 1982-12-23 GB GB08236592A patent/GB2114121B/en not_active Expired
- 1982-12-23 AT AT0467682A patent/AT380880B/de not_active IP Right Cessation
- 1982-12-23 CY CY137882A patent/CY1378A/xx unknown
- 1982-12-24 FR FR8221751A patent/FR2518994B1/fr not_active Expired
- 1982-12-27 CH CH7565/82A patent/CH653682A5/de not_active IP Right Cessation
- 1982-12-27 SE SE8207426A patent/SE449748B/sv not_active IP Right Cessation
- 1982-12-27 HU HU824172A patent/HU190827B/hu not_active IP Right Cessation
- 1982-12-27 PT PT76037A patent/PT76037B/pt not_active IP Right Cessation
- 1982-12-27 DE DE19823248138 patent/DE3248138A1/de active Granted
- 1982-12-28 BE BE0/209827A patent/BE895505A/fr not_active IP Right Cessation
- 1982-12-29 LU LU84562A patent/LU84562A1/fr unknown
-
1987
- 1987-03-27 SG SG296/87A patent/SG29687G/en unknown
- 1987-03-31 KE KE3714A patent/KE3714A/xx unknown
-
1988
- 1988-01-21 HK HK51/88A patent/HK5188A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed | ||
| MM | Patent lapsed |
Owner name: BRISTOL-MYERS CO |