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FI812046L - Foerfarande foer framstaellning av nya kefalosporiner med antibakteriell aktivitet - Google Patents

Foerfarande foer framstaellning av nya kefalosporiner med antibakteriell aktivitet

Info

Publication number
FI812046L
FI812046L FI812046A FI812046A FI812046L FI 812046 L FI812046 L FI 812046L FI 812046 A FI812046 A FI 812046A FI 812046 A FI812046 A FI 812046A FI 812046 L FI812046 L FI 812046L
Authority
FI
Finland
Prior art keywords
procedure
antibacterial activity
antibacterial
activity
Prior art date
Application number
FI812046A
Other languages
English (en)
Other versions
FI66876B (fi
FI66876C (fi
Inventor
David Alan Berges
George Lawrence Dunn
Original Assignee
Smithkline Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Corp filed Critical Smithkline Corp
Publication of FI812046L publication Critical patent/FI812046L/fi
Publication of FI66876B publication Critical patent/FI66876B/fi
Application granted granted Critical
Publication of FI66876C publication Critical patent/FI66876C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/247-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36Methylene radicals, substituted by sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI812046A 1980-07-03 1981-06-30 Foerfarande foer framstaellning av antibakteriellt aktiv 7beta(syn-2-metoxi-imino-2-(2-amino-4-tiazolyl)acetamido)-3-(1-(2-sulfaminoetyl)tetrazol-5-yltiometyl)-3-cefem-4-karboxylsyra FI66876C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/165,822 US4308267A (en) 1980-07-03 1980-07-03 7-[2-Alkoxyimino-2-(amino-thiazole)acetamido]-3-[1-(sulfaminoalkly)tetrazolthiomethyl]cephalosporins
US16582280 1980-07-03

Publications (3)

Publication Number Publication Date
FI812046L true FI812046L (fi) 1982-01-04
FI66876B FI66876B (fi) 1984-08-31
FI66876C FI66876C (fi) 1984-12-10

Family

ID=22600626

Family Applications (1)

Application Number Title Priority Date Filing Date
FI812046A FI66876C (fi) 1980-07-03 1981-06-30 Foerfarande foer framstaellning av antibakteriellt aktiv 7beta(syn-2-metoxi-imino-2-(2-amino-4-tiazolyl)acetamido)-3-(1-(2-sulfaminoetyl)tetrazol-5-yltiometyl)-3-cefem-4-karboxylsyra

Country Status (23)

Country Link
US (1) US4308267A (fi)
EP (1) EP0043713B1 (fi)
JP (1) JPS5745189A (fi)
KR (1) KR840002046B1 (fi)
AR (1) AR228606A1 (fi)
AT (1) ATE9585T1 (fi)
AU (1) AU547942B2 (fi)
CA (1) CA1151150A (fi)
DE (1) DE3166321D1 (fi)
DK (1) DK286981A (fi)
ES (1) ES503622A0 (fi)
FI (1) FI66876C (fi)
GR (1) GR74363B (fi)
HU (1) HU185934B (fi)
IE (1) IE51365B1 (fi)
IL (1) IL63206A (fi)
NO (1) NO812268L (fi)
NZ (1) NZ197573A (fi)
PH (1) PH17670A (fi)
PT (1) PT73292B (fi)
YU (1) YU162481A (fi)
ZA (1) ZA814484B (fi)
ZW (1) ZW15181A1 (fi)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4526977A (en) * 1981-10-07 1985-07-02 American Home Products Corporation 2-(3-Amino-5-isoxazolyl)-2-oxyimino-acetic acids

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4171362A (en) * 1975-10-30 1979-10-16 Smithkline Corporation 7-Acylamino-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins antibacterial compositions containing them and methods of treating bacterial infections with them
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
JPS52125188A (en) 1976-04-14 1977-10-20 Takeda Chem Ind Ltd Cephalosporin derivatives and their preparation
US4066762A (en) * 1976-07-12 1978-01-03 Smithkline Corporation Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid
DE2714880A1 (de) 1977-04-02 1978-10-26 Hoechst Ag Cephemderivate und verfahren zu ihrer herstellung
MC1259A1 (fr) 1978-05-30 1980-01-14 Hoffmann La Roche Derives acyles
US4220761A (en) * 1978-09-12 1980-09-02 Fujisawa Pharmaceutical Co., Ltd. 7-[Substituted oximinoacetamido]-3-[hydroxy alkyltetrazolo]cephalosporin derivatives

Also Published As

Publication number Publication date
PH17670A (en) 1984-11-02
ZW15181A1 (en) 1981-09-29
AR228606A1 (es) 1983-03-30
IE51365B1 (en) 1986-12-10
FI66876B (fi) 1984-08-31
DE3166321D1 (en) 1984-10-31
EP0043713B1 (en) 1984-09-26
NO812268L (no) 1982-01-04
KR840002046B1 (ko) 1984-11-06
KR830006310A (ko) 1983-09-20
NZ197573A (en) 1984-09-28
DK286981A (da) 1982-01-04
ES8203908A1 (es) 1982-04-01
AU7234381A (en) 1982-01-07
IE811481L (en) 1982-01-03
HU185934B (en) 1985-04-28
AU547942B2 (en) 1985-11-14
CA1151150A (en) 1983-08-02
ES503622A0 (es) 1982-04-01
ATE9585T1 (de) 1984-10-15
EP0043713A1 (en) 1982-01-13
FI66876C (fi) 1984-12-10
JPS5745189A (en) 1982-03-13
IL63206A (en) 1986-09-30
IL63206A0 (en) 1981-09-13
PT73292A (en) 1981-07-01
US4308267A (en) 1981-12-29
ZA814484B (en) 1982-07-28
GR74363B (fi) 1984-06-28
YU162481A (en) 1983-06-30
PT73292B (en) 1982-07-22

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: SMITHKLINE BECKMAN CORPORATION