FI20000354L - Perhydro-1H-pyrido/1,2-a/pyratsiinijohdannaiset - Google Patents

Perhydro-1H-pyrido/1,2-a/pyratsiinijohdannaiset Download PDF

Info

Publication number: FI20000354L
Authority: FI; Finland
Prior art keywords: perhydro; pyrido; pyrazine derivatives; pyrazine; derivatives
Prior art date: 1991-02-27

Application number

FI20000354A

Other languages

English (en)

Swedish (sv)

Other versions

FI112865B (fi

Inventor

Gene Michael Bright

Kishor Amratlal Desai

Thomas Francis Seeger

Original Assignee

Pfizer

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1991-02-27

Filing date

2000-02-17

Publication date

2000-02-17

2000-02-17 Application filed by Pfizer filed Critical Pfizer

2000-02-17 Publication of FI20000354L publication Critical patent/FI20000354L/fi

2004-01-30 Application granted granted Critical

2004-01-30 Publication of FI112865B publication Critical patent/FI112865B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Chemical Kinetics & Catalysis (AREA)
Psychiatry (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Biomedical Technology (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

FI20000354A 1991-02-27 2000-02-17 Perhydro-1H-pyrido[1,2-a]pyratsiinijohdannaiset FI112865B (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US07/661,791 US5157034A (en)	1991-02-27	1991-02-27	Neuroleptic perhydro-1H-pyrido[1,2-a]pyrazines
US66179191		1991-02-27
PCT/US1991/008378 WO1992015580A1 (en)	1991-02-27	1991-11-18	NEUROLEPTIC PERHYDRO-1H-PYRIDO[1,2-a]PYRAZINES
US9108378		1991-11-18

Publications (2)

Publication Number	Publication Date
FI20000354L true FI20000354L (fi)	2000-02-17
FI112865B FI112865B (fi)	2004-01-30

Family

ID=24655130

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
FI933753A FI105030B (fi)	1991-02-27	1993-08-26	Menetelmä terapeuttisesti käyttökelpoisten raseemisten tai optisesti aktiivisten 2-(bentso[d]isoksatsol- ja -iso-tiatsol-3-yyli)-perhydro-1H-pyrido[1,2-a]-pyratsiinijohdannaisten valmistamiseksi
FI20000354A FI112865B (fi)	1991-02-27	2000-02-17	Perhydro-1H-pyrido[1,2-a]pyratsiinijohdannaiset
FI20030361A FI114214B (fi)	1991-02-27	2003-03-11	Perhydro-1H-pyrido[1,2-a]pyratsiinijohdannaiset

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
FI933753A FI105030B (fi)	1991-02-27	1993-08-26	Menetelmä terapeuttisesti käyttökelpoisten raseemisten tai optisesti aktiivisten 2-(bentso[d]isoksatsol- ja -iso-tiatsol-3-yyli)-perhydro-1H-pyrido[1,2-a]-pyratsiinijohdannaisten valmistamiseksi

Family Applications After (1)

Application Number	Title	Priority Date	Filing Date
FI20030361A FI114214B (fi)	1991-02-27	2003-03-11	Perhydro-1H-pyrido[1,2-a]pyratsiinijohdannaiset

Country Status (24)

Country	Link
US (1)	US5157034A (fi)
EP (1)	EP0573467B1 (fi)
JP (1)	JP2546770B2 (fi)
KR (1)	KR0163413B1 (fi)
AT (1)	ATE123284T1 (fi)
AU (1)	AU652422B2 (fi)
CA (2)	CA2163274C (fi)
DE (2)	DE69110135T2 (fi)
DK (1)	DK0573467T3 (fi)
ES (1)	ES2073914T3 (fi)
FI (3)	FI105030B (fi)
HU (1)	HU216637B (fi)
IE (1)	IE67190B1 (fi)
IL (2)	IL101021A (fi)
MX (1)	MX9200803A (fi)
MY (1)	MY108185A (fi)
NO (1)	NO300847B1 (fi)
NZ (1)	NZ241739A (fi)
PT (1)	PT100160B (fi)
RU (1)	RU2090565C1 (fi)
TW (1)	TW207540B (fi)
WO (1)	WO1992015580A1 (fi)
YU (1)	YU48311B (fi)
ZA (1)	ZA921405B (fi)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA2101252C (en) *	1991-02-27	1998-02-17	Frank J. Urban	Process for preparing trans-piperidine-2,5- dicarboxylates
CA2138018C (en) *	1992-06-16	1998-01-27	Frank J. Urban	Process and intermediates for bis-aza-bicyclic anxiolytic agents
WO1996010570A1 (en) *	1994-09-30	1996-04-11	Pfizer Inc.	NEUROLEPTIC 2,7-DISUBSTITUTED PERHYDRO-1H-PYRIDO[1,2-a]PYRAZINES
US6231833B1 (en)	1999-08-05	2001-05-15	Pfizer Inc	2,7-substituted octahydro-1H-pyrido[1,2-A]pyrazine derivatives as ligands for serotonin receptors
MX9702350A (es) *	1994-09-30	1997-06-28	Pfizer	Derivados 2,7-sustituidos de octahidro-1h-pirido (1,2-a) pirazina.
PA8469101A1 (es) *	1998-04-09	2000-09-29	Pfizer Prod Inc	Ligandos azabiciclicos de receptores 5ht1
UA62015C2 (en) *	1998-12-28	2003-12-15	Pfizer Prod Inc	Benzoizoxazol derivatives, a pharmaceutical composition (variants) based thereon (variants) and a method for treatment (variants)
DE19960204A1 (de) *	1999-12-14	2001-06-28	Aventis Pharma Gmbh	Substituierte Norlbornylamino-Derivate, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
PL378749A1 (pl) *	2003-03-12	2006-05-15	Pfizer Products Inc.	Azabicykliczne pochodne pirydyloksymetylowe i benzoizoksazolowe
KR101120414B1 (ko)	2003-04-24	2012-04-12	인사이트 코포레이션	메탈로프로테아제의 억제제로서의 아자 스피로 알칸 유도체
US7910108B2 (en) *	2006-06-05	2011-03-22	Incyte Corporation	Sheddase inhibitors combined with CD30-binding immunotherapeutics for the treatment of CD30 positive diseases
JP6440625B2 (ja)	2012-11-14	2018-12-19	ザ・ジョンズ・ホプキンス・ユニバーシティー	精神分裂病を処置するための方法および組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4681938A (en) *	1984-08-27	1987-07-21	Ciba-Geigy Corporation	Novel polycyclic hydrazones of rifamycins, their manufacture, and their pharmaceutical compositions for treating tuberculosis
US4831031A (en) *	1988-01-22	1989-05-16	Pfizer Inc.	Aryl piperazinyl-(C2 or C4) alkylene heterocyclic compounds having neuroleptic activity
US4957916A (en) *	1988-08-05	1990-09-18	Janssen Pharmaceutica N.V.	Antipsychotic 3-piperazinylbenzazole derivatives
MX19222A (es) *	1989-01-23	1993-12-01	Pfizer	Agentes ansioliticos bis-aza-biciclicos

1991
- 1991-02-27 US US07/661,791 patent/US5157034A/en not_active Expired - Lifetime
- 1991-11-18 DK DK92904861.9T patent/DK0573467T3/da active
- 1991-11-18 KR KR1019930702554A patent/KR0163413B1/ko not_active Expired - Fee Related
- 1991-11-18 DE DE69110135T patent/DE69110135T2/de not_active Expired - Fee Related
- 1991-11-18 AT AT92904861T patent/ATE123284T1/de not_active IP Right Cessation
- 1991-11-18 CA CA002163274A patent/CA2163274C/en not_active Expired - Fee Related
- 1991-11-18 RU RU9193045711A patent/RU2090565C1/ru not_active IP Right Cessation
- 1991-11-18 HU HU9302427A patent/HU216637B/hu unknown
- 1991-11-18 DE DE9190206U patent/DE9190206U1/de not_active Expired - Lifetime
- 1991-11-18 CA CA002101518A patent/CA2101518C/en not_active Expired - Fee Related
- 1991-11-18 EP EP92904861A patent/EP0573467B1/en not_active Expired - Lifetime
- 1991-11-18 WO PCT/US1991/008378 patent/WO1992015580A1/en not_active Ceased
- 1991-11-18 ES ES92904861T patent/ES2073914T3/es not_active Expired - Lifetime
- 1991-11-18 JP JP4505183A patent/JP2546770B2/ja not_active Expired - Fee Related
- 1991-11-18 AU AU12599/92A patent/AU652422B2/en not_active Ceased
1992
- 1992-01-21 TW TW081100420A patent/TW207540B/zh active
- 1992-02-20 IL IL10102192A patent/IL101021A/en not_active IP Right Cessation
- 1992-02-20 IL IL11232595A patent/IL112325A/xx not_active IP Right Cessation
- 1992-02-25 PT PT100160A patent/PT100160B/pt not_active IP Right Cessation
- 1992-02-25 MX MX9200803A patent/MX9200803A/es not_active IP Right Cessation
- 1992-02-26 ZA ZA921405A patent/ZA921405B/xx unknown
- 1992-02-26 IE IE920601A patent/IE67190B1/en not_active IP Right Cessation
- 1992-02-26 MY MYPI92000318A patent/MY108185A/en unknown
- 1992-02-26 YU YU19892A patent/YU48311B/sh unknown
- 1992-02-26 NZ NZ24173992A patent/NZ241739A/en not_active IP Right Cessation
1993
- 1993-08-26 NO NO933049A patent/NO300847B1/no unknown
- 1993-08-26 FI FI933753A patent/FI105030B/fi not_active IP Right Cessation
2000
- 2000-02-17 FI FI20000354A patent/FI112865B/fi not_active IP Right Cessation
2003
- 2003-03-11 FI FI20030361A patent/FI114214B/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
AU652422B2 (en)	1994-08-25
IE67190B1 (en)	1996-03-06
DK0573467T3 (da)	1995-10-09
PT100160B (pt)	1999-09-30
RU2090565C1 (ru)	1997-09-20
NO933049L (no)	1993-08-26
KR930703315A (ko)	1993-11-29
MY108185A (en)	1996-08-30
FI933753A0 (fi)	1993-08-26
FI114214B (fi)	2004-09-15
ES2073914T3 (es)	1995-08-16
FI20030361L (fi)	2003-03-11
DE9190206U1 (de)	1993-10-14
US5157034A (en)	1992-10-20
NO300847B1 (no)	1997-08-04
JPH06500120A (ja)	1994-01-06
ATE123284T1 (de)	1995-06-15
TW207540B (fi)	1993-06-11
KR0163413B1 (ko)	1998-12-01
FI112865B (fi)	2004-01-30
JP2546770B2 (ja)	1996-10-23
CA2163274A1 (en)	1992-08-28
DE69110135D1 (de)	1995-07-06
EP0573467B1 (en)	1995-05-31
EP0573467A1 (en)	1993-12-15
IL101021A (en)	1996-03-31
MX9200803A (es)	1992-08-31
NZ241739A (en)	1994-07-26
CA2163274C (en)	1999-02-09
CA2101518A1 (en)	1992-08-28
IL112325A0 (en)	1995-03-30
CA2101518C (en)	1997-11-25
HUT66965A (en)	1995-01-30
WO1992015580A1 (en)	1992-09-17
YU48311B (sh)	1998-05-15
DE69110135T2 (de)	1995-10-19
IL112325A (en)	1997-08-14
AU1259992A (en)	1992-10-06
ZA921405B (en)	1993-08-26
HU216637B (hu)	1999-07-28
FI105030B (fi)	2000-05-31
IE920601A1 (en)	1992-09-09
NO933049D0 (no)	1993-08-26
PT100160A (pt)	1993-05-31
FI933753L (fi)	1993-08-26
YU19892A (sh)	1994-11-15
HU9302427D0 (en)	1993-11-29

Publication	Publication Date	Title
MX9202838A (es)	1993-02-01	Imidazo[1,5-a]quinoxalinas.
NL300250I1 (nl)	2007-02-01	Chinuclidinederivaten.
DK0680488T3 (da)	1999-01-25	2,6-Diaminopurinderivater
FI962155L (fi)	1996-05-22	Uudet 9-hydroksipyrido (1,2-a) pyrimidin-4-onieetterijohdannaiset
MX9205145A (es)	1993-04-01	Nuevos derivados heterociclicos.
FI924160A7 (fi)	1993-03-19	Benzanilidderivat
NO922182L (no)	1992-12-04	Krystallinske oksatiolan-derivater
FI923314L (fi)	1993-01-26	Substituerade cyklopropylamino-1,3,5-triaziner
DE69201748D1 (de)	1995-04-27	Pyrazinderivate.
DE69114654D1 (de)	1995-12-21	Fluorierte Diazabicycloalkan-Derivate.
FI20000354L (fi)	2000-02-17	Perhydro-1H-pyrido/1,2-a/pyratsiinijohdannaiset
FI971310L (fi)	1997-03-27	2,7-substituoituja oktahydro-1H-pyrido/1,2-a/pyratsiinijohdannaisia
FI923290L (fi)	1993-01-20	Imidazo(2,1-b)bensotiazol-3-acetamidderivat
FI920394L (fi)	1992-08-02	3-kinuklidinderivat.
FI864891A7 (fi)	1987-06-21	Foerfarande foer framstaellning av 6,7,8,9-tetrahydro-10-metylpyrido/1,2-a/indol-9-aminer och deras derivat.
FI941377L (fi)	1994-03-24	Neuroleptisiä 2-substituoituja perhydro-1-H-pyrido/1,2-a/-pyratsiineja
FI925258A7 (fi)	1993-05-27	Foerfarande foer framstaellning av 2-substituerade 4,6-dialkoxipyrimidiner
DE69122555D1 (de)	1996-11-14	2,4-Dihydroxyadipinsäurederivate
FI943999A7 (fi)	1995-03-03	Pyrido(1,2,3-d,e)(1,3,4)bentsoksadiatsiinijohdannaisia
FI931794L (fi)	1993-10-23	Monokvaternaera 2,16-bispiperidinylandrostanderivat
FI922443A0 (fi)	1992-05-27	Framstaellning av 6-0-alkylelsamicin-a -derivat.
FI935657L (fi)	1993-12-16	Foerfarande foer framstaellning av 3,4-dihydroxi-5-nitrobensaldehyd
FI923201L (fi)	1993-01-16	3,4-dehyropiperidinderivat
DE69411093D1 (de)	1998-07-23	Pyrazin-derivate
MX9202291A (es)	1992-11-01	Derivados carboxamido-(3,2n)-carbociclico-2-amino tetralinas.

Legal Events

Date	Code	Title	Description
2007-05-31	MA	Patent expired