FI20000038L - Tiadiazolyl- och oxadiazolylfenyloxazolidinoner som antibakteriella medel - Google Patents
Tiadiazolyl- och oxadiazolylfenyloxazolidinoner som antibakteriella medel Download PDFInfo
- Publication number
- FI20000038L FI20000038L FI20000038A FI20000038A FI20000038L FI 20000038 L FI20000038 L FI 20000038L FI 20000038 A FI20000038 A FI 20000038A FI 20000038 A FI20000038 A FI 20000038A FI 20000038 L FI20000038 L FI 20000038L
- Authority
- FI
- Finland
- Prior art keywords
- oxadiazolylphenyloxazolidinones
- thiadiazolyl
- antibacterial agents
- antibacterial
- agents
- Prior art date
Links
- OTZCEFOPYGRBFK-UHFFFAOYSA-N 4-(oxadiazol-4-yl)-3-phenyl-1,3-oxazolidin-2-one Chemical class O=C1OCC(C=2N=NOC=2)N1C1=CC=CC=C1 OTZCEFOPYGRBFK-UHFFFAOYSA-N 0.000 title 1
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 125000001113 thiadiazolyl group Chemical group 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5290797P | 1997-07-11 | 1997-07-11 | |
| US6474697P | 1997-11-07 | 1997-11-07 | |
| PCT/US1998/013437 WO1999002525A1 (en) | 1997-07-11 | 1998-07-08 | Thiadiazolyl and oxadiazolyl phenyl oxazolidinone antibacterial agents |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI20000038L true FI20000038L (sv) | 2000-03-10 |
| FI20000038A7 FI20000038A7 (sv) | 2000-03-10 |
Family
ID=26731233
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI20000038A FI20000038A7 (sv) | 1997-07-11 | 2000-01-10 | Tiadiazolyl- och oxadiazolylfenyloxazolidinoner som antibakteriella medel |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5977373A (sv) |
| EP (1) | EP0994874A1 (sv) |
| JP (1) | JP2002513424A (sv) |
| KR (1) | KR20010021645A (sv) |
| CN (1) | CN1211384C (sv) |
| AU (1) | AU729745B2 (sv) |
| CA (1) | CA2294293A1 (sv) |
| FI (1) | FI20000038A7 (sv) |
| NO (1) | NO316715B1 (sv) |
| NZ (1) | NZ502253A (sv) |
| WO (1) | WO1999002525A1 (sv) |
Families Citing this family (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE19755268A1 (de) * | 1997-12-12 | 1999-06-17 | Merck Patent Gmbh | Benzamidinderivate |
| DE69902526T2 (de) * | 1998-05-18 | 2003-04-03 | Pharmacia & Upjohn Co., Kalamazoo | Verbesserung der antibakteriellen wirkung von oxazolidinon durch arginin derivate |
| AU753988B2 (en) | 1998-06-05 | 2002-10-31 | Astrazeneca Ab | Oxazolidinone derivatives, process for their preparation and pharmaceutical compositions containing them |
| EP1102536B1 (de) * | 1998-08-04 | 2003-05-02 | Ciba SC Holding AG | Verwendung von Oxathiazolonen als Mikrobizide |
| CA2374383A1 (en) * | 1999-07-28 | 2001-02-08 | Pharmacia & Upjohn Company | Oxazolidinones and their use as antiinfectives |
| US6297242B1 (en) * | 1999-08-12 | 2001-10-02 | Ortho-Mcneil Pharmaceutical, Inc. | N-substituted amidine and guanidine oxazolidinone antibacterials and methods of use thereof |
| GB9928568D0 (en) | 1999-12-03 | 2000-02-02 | Zeneca Ltd | Chemical compounds |
| DE19962924A1 (de) | 1999-12-24 | 2001-07-05 | Bayer Ag | Substituierte Oxazolidinone und ihre Verwendung |
| US6552204B1 (en) * | 2000-02-04 | 2003-04-22 | Roche Colorado Corporation | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one |
| GB0009803D0 (en) | 2000-04-25 | 2000-06-07 | Astrazeneca Ab | Chemical compounds |
| DE10129725A1 (de) | 2001-06-20 | 2003-01-02 | Bayer Ag | Kombinationstherapie substituierter Oxazolidinone |
| GB0118407D0 (en) * | 2001-07-27 | 2001-09-19 | Cipla Ltd | Oxazolidinone derivatives as antibacterial agents |
| WO2004026848A1 (en) * | 2002-09-20 | 2004-04-01 | Lupin Limited | Oxazolidinone derivatives, process for their preperation and their use as antimycobacterial agents |
| DE10300111A1 (de) | 2003-01-07 | 2004-07-15 | Bayer Healthcare Ag | Verfahren zur Herstellung von 5-Chlor-N-({(5S)-2-oxo-3-[4-(3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl}-methyl)-2-thiophencarboxamid |
| WO2005019213A1 (en) * | 2003-08-22 | 2005-03-03 | Pharmacia & Upjohn Company Llc | N-aryl-2-cyanooxazolidinones and their derivatives |
| DE10355461A1 (de) | 2003-11-27 | 2005-06-23 | Bayer Healthcare Ag | Verfahren zur Herstellung einer festen, oral applizierbaren pharmazeutischen Zusammensetzung |
| KR100854211B1 (ko) | 2003-12-18 | 2008-08-26 | 동아제약주식회사 | 신규한 옥사졸리디논 유도체, 그의 제조방법 및 이를유효성분으로 하는 항생제용 약학 조성물 |
| DE102004062475A1 (de) * | 2004-12-24 | 2006-07-06 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit modifizierter Freisetzung |
| EP1685841A1 (en) | 2005-01-31 | 2006-08-02 | Bayer Health Care Aktiengesellschaft | Prevention and treatment of thromboembolic disorders |
| DE102005045518A1 (de) | 2005-09-23 | 2007-03-29 | Bayer Healthcare Ag | 2-Aminoethoxyessigsäure-Derivate und ihre Verwendung |
| DE102005047558A1 (de) * | 2005-10-04 | 2008-02-07 | Bayer Healthcare Ag | Kombinationstherapie substituierter Oxazolidinone zur Prophylaxe und Behandlung von cerebralen Durchblutungsstörungen |
| EP1934208B1 (de) | 2005-10-04 | 2011-03-23 | Bayer Schering Pharma Aktiengesellschaft | Neue polymorphe form von 5-chlor-n-({ ( 5s )-2-0x0-3-[4-( 3-oxo-4-morpholinyl)-phenyl]-1,3-oxazolidin-5-yl} -methyl)-2-thiophencarboxamid |
| DE102005047561A1 (de) | 2005-10-04 | 2007-04-05 | Bayer Healthcare Ag | Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung |
| EP2072514A1 (en) * | 2007-12-17 | 2009-06-24 | Ferrer Internacional, S.A. | 1(2)H-tetrazol-5-yl-phenyl-oxazolidinones as antibacterial agents |
| TW201043618A (en) | 2009-03-10 | 2010-12-16 | Sanofi Aventis | Intermediate compound for synthesizing pharmaceutical agent and production method thereof |
| CN101619061B (zh) * | 2009-08-11 | 2014-12-17 | 沈阳药科大学 | 氰基吡啶基取代的噁唑烷酮类化合物 |
| US8916567B2 (en) | 2009-11-04 | 2014-12-23 | Universal Technology Alliance, Inc. | Certain crystalline hydrates, pharmaceutical compositions thereof and methods for preparation and use thereof |
| CN102190656B (zh) * | 2010-03-16 | 2014-03-26 | 山东轩竹医药科技有限公司 | 含有五元杂环的噁唑烷酮抗菌素 |
| UA112876C2 (uk) * | 2011-09-29 | 2016-11-10 | Сюаньчжу Фарма Ко., Лтд. | Біарилгетероциклзаміщені оксазолідинонові антибактеріальні засоби |
| CN104364240B (zh) * | 2012-06-08 | 2017-02-22 | 四川贝力克生物技术有限责任公司 | 一种用于预防或治疗分支杆菌疾病的药物 |
| US9862710B2 (en) | 2013-03-15 | 2018-01-09 | Istituto Euro Mediterraneo Di Scienza E Tecnologia | 1,2,4-oxadiazol compounds active against gram-positive pathogens |
| WO2014141218A1 (en) * | 2013-03-15 | 2014-09-18 | Università Degli Studi Di Milano - Bicocca | Novel 1, 2, 4-oxadiazol compounds active against gram-positive pathogens |
| ITRM20130155A1 (it) * | 2013-03-15 | 2014-09-16 | I E Me S T Istituto Euro Mediter Raneo Di Scien | Nuovi composti 1,2,4-ossadiazolici attivi contro patogeni gram-positivi. |
| CN105153143A (zh) * | 2015-10-23 | 2015-12-16 | 河北大学 | 一种含噁二唑/噻二唑的硫脲嘧啶衍生物及其制备方法和应用 |
| MX2018006474A (es) * | 2015-12-02 | 2018-08-01 | Syngenta Participations Ag | Derivados de oxadiazol microbicidas. |
| BR112018067426B1 (pt) * | 2016-03-01 | 2022-10-04 | Basf Se | Compostos da fórmula i, mistura, composição agroquímica, uso dos compostos e método para combater fungos nocivos fitopatogênicos |
| CN111320618A (zh) * | 2018-12-17 | 2020-06-23 | 好医生药业集团有限公司 | 一类新型抗葡萄球菌的小分子化合物及其制法和用途 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4948801A (en) * | 1988-07-29 | 1990-08-14 | E. I. Du Pont De Nemours And Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
| US5254577A (en) * | 1988-07-29 | 1993-10-19 | The Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives useful as antibacterial agents |
| US5130316A (en) * | 1988-07-29 | 1992-07-14 | Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazlidinyl arylbenzene derivatives useful as antibacterial agents |
| US5043443A (en) * | 1988-07-29 | 1991-08-27 | Du Pont Merck Pharmaceutical Company | Aminomethyloxooxazolidinyl arylbenzene derivatives |
| KR100257418B1 (ko) * | 1991-11-01 | 2000-05-15 | 로렌스 티. 마이젠헬더 | 치환된 아릴-및 헤테로아릴-페닐옥사졸리디논 |
| SK283420B6 (sk) * | 1992-05-08 | 2003-07-01 | Pharmacia & Upjohn Company | Antimikrobiálne oxazolidinóny obsahujúce substituované diazínové skupiny |
| US5688792A (en) * | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
| CZ231497A3 (cs) * | 1995-02-03 | 1998-08-12 | Pharmacia & Upjohn Company | Antimikrobiální fenyloxazolidinony substituované heteroaromatickým kruhem |
| US5968962A (en) * | 1995-09-01 | 1999-10-19 | Pharmacia & Upjohn Company | Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings |
| MY116093A (en) * | 1996-02-26 | 2003-11-28 | Upjohn Co | Azolyl piperazinyl phenyl oxazolidinone antimicrobials |
-
1998
- 1998-07-08 NZ NZ502253A patent/NZ502253A/en unknown
- 1998-07-08 WO PCT/US1998/013437 patent/WO1999002525A1/en not_active Ceased
- 1998-07-08 EP EP98932933A patent/EP0994874A1/en not_active Withdrawn
- 1998-07-08 KR KR1020007000203A patent/KR20010021645A/ko not_active Ceased
- 1998-07-08 US US09/111,995 patent/US5977373A/en not_active Expired - Fee Related
- 1998-07-08 CN CNB98806846XA patent/CN1211384C/zh not_active Expired - Fee Related
- 1998-07-08 CA CA002294293A patent/CA2294293A1/en not_active Abandoned
- 1998-07-08 AU AU82713/98A patent/AU729745B2/en not_active Ceased
- 1998-07-08 JP JP50871199A patent/JP2002513424A/ja not_active Withdrawn
-
2000
- 2000-01-10 NO NO20000125A patent/NO316715B1/no not_active IP Right Cessation
- 2000-01-10 FI FI20000038A patent/FI20000038A7/sv not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| EP0994874A1 (en) | 2000-04-26 |
| CA2294293A1 (en) | 1999-01-21 |
| US5977373A (en) | 1999-11-02 |
| NO20000125L (no) | 2000-03-10 |
| NO20000125D0 (no) | 2000-01-10 |
| AU729745B2 (en) | 2001-02-08 |
| AU8271398A (en) | 1999-02-08 |
| JP2002513424A (ja) | 2002-05-08 |
| WO1999002525A1 (en) | 1999-01-21 |
| NO316715B1 (no) | 2004-04-13 |
| FI20000038A7 (sv) | 2000-03-10 |
| NZ502253A (en) | 2001-06-29 |
| KR20010021645A (ko) | 2001-03-15 |
| CN1211384C (zh) | 2005-07-20 |
| CN1261889A (zh) | 2000-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MA | Patent expired |