ES8705466A1 - Human endogenous cancer regulatory factors. - Google Patents
Human endogenous cancer regulatory factors.Info
- Publication number
- ES8705466A1 ES8705466A1 ES550833A ES550833A ES8705466A1 ES 8705466 A1 ES8705466 A1 ES 8705466A1 ES 550833 A ES550833 A ES 550833A ES 550833 A ES550833 A ES 550833A ES 8705466 A1 ES8705466 A1 ES 8705466A1
- Authority
- ES
- Spain
- Prior art keywords
- regulatory factors
- human endogenous
- endogenous cancer
- cancer regulatory
- range
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 4
- 201000011510 cancer Diseases 0.000 title abstract 4
- 102000037983 regulatory factors Human genes 0.000 title abstract 4
- 108091008025 regulatory factors Proteins 0.000 title abstract 4
- 239000002246 antineoplastic agent Substances 0.000 abstract 1
- 239000003638 chemical reducing agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 239000003104 tissue culture media Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4702—Regulators; Modulating activity
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Toxicology (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
Human endogenous cancer regulatory factors useful as anti-tumor agents having a molecular weight in the range from 17,000 to 30,000, and pharmaceutical compositions containing the same. The low-molecular-weight, human endogenous cancer regulatory factors of the present invention are obtained by growing human monocytic cells or cloned strains therefrom in a tissue culture medium to form human endogenous cancer regulatory factors having a molecular weight in the range from 50,000 to 92,000 and an isoelectric point in the pH range from 6.0 to 8.5, followed by treatment with a reducing agent and/or a protein denaturing agent.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP472185 | 1985-01-14 | ||
| JP13667085 | 1985-06-21 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8705466A1 true ES8705466A1 (en) | 1987-05-01 |
| ES550833A0 ES550833A0 (en) | 1987-05-01 |
Family
ID=26338538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES550833A Expired ES8705466A1 (en) | 1985-01-14 | 1986-01-13 | Human endogenous cancer regulatory factors. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0216929A1 (en) |
| KR (1) | KR870700072A (en) |
| DK (1) | DK436786A (en) |
| ES (1) | ES8705466A1 (en) |
| NO (1) | NO863657L (en) |
| PT (1) | PT81823B (en) |
| WO (1) | WO1986004069A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0193032A3 (en) * | 1985-02-13 | 1988-04-06 | Gesellschaft für Biotechnologische Forschung mbH (GBF) | Composition comprising or containing cytokinin, process for its preparation, dna sequence and its use |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8204382L (en) * | 1981-07-21 | 1983-01-22 | Hayashibara Biochem Lab | PUT TO MAKE MALCELLY FACTOR AND USE THEREOF |
| ZA834976B (en) * | 1982-07-30 | 1984-08-29 | Genentech Inc | Human lymphotoxin |
-
1986
- 1986-01-10 PT PT81823A patent/PT81823B/en not_active IP Right Cessation
- 1986-01-13 EP EP86900636A patent/EP0216929A1/en not_active Withdrawn
- 1986-01-13 KR KR1019860700634A patent/KR870700072A/en not_active Withdrawn
- 1986-01-13 ES ES550833A patent/ES8705466A1/en not_active Expired
- 1986-01-13 WO PCT/JP1986/000011 patent/WO1986004069A1/en not_active Ceased
- 1986-09-12 NO NO863657A patent/NO863657L/en unknown
- 1986-09-12 DK DK436786A patent/DK436786A/en not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES550833A0 (en) | 1987-05-01 |
| DK436786D0 (en) | 1986-09-12 |
| PT81823B (en) | 1987-11-30 |
| PT81823A (en) | 1986-02-01 |
| NO863657D0 (en) | 1986-09-12 |
| NO863657L (en) | 1986-09-12 |
| KR870700072A (en) | 1987-02-28 |
| EP0216929A1 (en) | 1987-04-08 |
| WO1986004069A1 (en) | 1986-07-17 |
| DK436786A (en) | 1986-09-12 |
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