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ES8704446A1 - Procedimiento para la preparacion de derivados de all-cis-1,3,5-triamino-2,4,6-trihidrociclohexano - Google Patents

Procedimiento para la preparacion de derivados de all-cis-1,3,5-triamino-2,4,6-trihidrociclohexano

Info

Publication number
ES8704446A1
ES8704446A1 ES551485A ES551485A ES8704446A1 ES 8704446 A1 ES8704446 A1 ES 8704446A1 ES 551485 A ES551485 A ES 551485A ES 551485 A ES551485 A ES 551485A ES 8704446 A1 ES8704446 A1 ES 8704446A1
Authority
ES
Spain
Prior art keywords
alkyl
groups
triamino
cis
alkyl groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES551485A
Other languages
English (en)
Other versions
ES551485A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Vifor International AG
Original Assignee
Laboratorien Hausmann AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratorien Hausmann AG filed Critical Laboratorien Hausmann AG
Publication of ES551485A0 publication Critical patent/ES551485A0/es
Publication of ES8704446A1 publication Critical patent/ES8704446A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/383—Cycloaliphatic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C07C215/30—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE ALL-CIS-1,3,5-TRIAMINO-2,4,6-TRIHIDROCICLOHEXANO, DE FORMULA GENERAL (I), Y SUS SALES ACIDAS INORGANICAS U ORGANICAS FARMACOLOGICAMENTE USUALES Y SUS SALES CUATERNARIAS DE AMONIO. COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, SE HIDROGENA CATALITICAMENTE LA TRINITROFLOROGLUCINA O SU SAL METALICA MONOALCALINA; SEGUNDA, EL PRODUCTO OBTENIDO SE ALQUILA O ACILIZA EN FORMA DE AMINA LIBRE O DE SU SAL; Y POR ULTIMO, SE ALQUILA EN SU CASO EL PRODUCTO OBTENIDO, ESPECIALMENTE EL PRODUCTO DE ALQUILACION, EN LOS CORRESPONDIENTES COMPUESTOS MONO, DI O TRICUATERNARIOS. DE APLICACION EN LA PREPARACION DE PRODUCTOS FARMACEUTICOS PARA UTILIZACION TERAPEUTICA EN LOS CASOS DE EXCESO DE HIERRO EN EL CUERPO ANIMAL O DEL HOMBRE.
ES551485A 1985-02-02 1986-01-31 Procedimiento para la preparacion de derivados de all-cis-1,3,5-triamino-2,4,6-trihidrociclohexano Expired ES8704446A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19853503614 DE3503614A1 (de) 1985-02-02 1985-02-02 All-cis-1,3,5-triamino-2,4,6-cyclohexantriol-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische praeparate

Publications (2)

Publication Number Publication Date
ES551485A0 ES551485A0 (es) 1987-04-16
ES8704446A1 true ES8704446A1 (es) 1987-04-16

Family

ID=6261535

Family Applications (1)

Application Number Title Priority Date Filing Date
ES551485A Expired ES8704446A1 (es) 1985-02-02 1986-01-31 Procedimiento para la preparacion de derivados de all-cis-1,3,5-triamino-2,4,6-trihidrociclohexano

Country Status (13)

Country Link
US (1) US4794197A (es)
EP (1) EP0190676B1 (es)
JP (1) JP2519205B2 (es)
KR (1) KR900006133B1 (es)
AR (1) AR242177A1 (es)
AT (1) ATE41654T1 (es)
AU (1) AU589156B2 (es)
CA (1) CA1289963C (es)
DE (2) DE3503614A1 (es)
ES (1) ES8704446A1 (es)
GR (1) GR860301B (es)
IN (1) IN166368B (es)
PT (1) PT81955B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH679742A5 (es) * 1990-01-09 1992-04-15 Byk Gulden Lomberg Chem Fab
DE4028139A1 (de) * 1990-09-05 1992-03-12 Hausmann Ag Labor Verwendung der komplexe radioaktiver metallionen mit all-cis-1,3,5-triamino-2,4,6-cyclohexantriol und seinen derivaten fuer roentgendiagnostische zwecke und in der tumortherapie sowie zur herstellung von mitteln fuer roentgendiagnostische zwecke und fuer die tumortherapie
US6673537B1 (en) 1992-08-19 2004-01-06 Board Of Regents, University Of Nebraska-Lincoln Promoters from chlorella virus genes providing for expression of genes in prokaryotic and eukaryotic hosts
US5563328A (en) 1992-08-19 1996-10-08 Board Of Regents, University Of Nebraska-Lincoln Promoters from chlorella virus genes providing for expression of genes in prokaryotic and eukaryotic hosts
FR2779711B1 (fr) * 1998-06-12 2000-07-07 Commissariat Energie Atomique Procede de separation des cations lanthanides trivalents par complexation selective
US7057073B2 (en) * 2003-08-04 2006-06-06 Regents Of The University Of California Synthesis of trinitrophloroglucinol and triaminotrinitrobenzene (TATB)
EP2849804A1 (en) 2012-05-18 2015-03-25 Bayer Pharma Aktiengesellschaft Bis azainositol heavy metal complexes for x-ray imaging
EP2796152A1 (en) 2013-04-25 2014-10-29 Bayer Pharma Aktiengesellschaft Unsymmetrical Bis Azainositol Hafnium Complexes for X-Ray Imaging
EP2873670A1 (en) 2013-11-14 2015-05-20 Bayer Pharma Aktiengesellschaft Bis azainositol zirconium complexes for X-ray imaging

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR694M (es) 1959-10-08 1961-07-24
FR1522204A (fr) * 1963-01-21 1968-04-26 Upjohn Co Actinamine et ses dérivés et leur procédé de fabrication
US3496196A (en) * 1965-10-02 1970-02-17 Tanabe Pharm Co Ltd 4,6-diazido-4,6-dideoxy-myo-inositol tetraacylates
DE2360176A1 (de) * 1973-12-03 1975-06-05 Basf Ag Verfahren zur herstellung von 2,4,6- substituierten cyclohexan-1,3,5-triolen
DE2537682C2 (de) * 1975-08-23 1984-02-02 Basf Ag, 6700 Ludwigshafen Epoxy-cyclohexen - Derivate

Also Published As

Publication number Publication date
US4794197A (en) 1988-12-27
AU589156B2 (en) 1989-10-05
IN166368B (es) 1990-04-21
ES551485A0 (es) 1987-04-16
AR242177A1 (es) 1993-03-31
KR900006133B1 (ko) 1990-08-24
PT81955A (en) 1986-03-01
PT81955B (pt) 1988-07-01
JPS61210058A (ja) 1986-09-18
CA1289963C (en) 1991-10-01
EP0190676B1 (de) 1989-03-22
JP2519205B2 (ja) 1996-07-31
AU5285986A (en) 1986-10-16
EP0190676A1 (de) 1986-08-13
DE3662520D1 (en) 1989-04-27
ATE41654T1 (de) 1989-04-15
DE3503614C2 (es) 1987-11-26
KR860006432A (ko) 1986-09-11
DE3503614A1 (de) 1986-08-07
GR860301B (en) 1986-06-02

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20041004