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ES8701177A1 - Procedimiento para preparar derivados de pirazol-(1,5a)piri-dina - Google Patents

Procedimiento para preparar derivados de pirazol-(1,5a)piri-dina

Info

Publication number
ES8701177A1
ES8701177A1 ES544773A ES544773A ES8701177A1 ES 8701177 A1 ES8701177 A1 ES 8701177A1 ES 544773 A ES544773 A ES 544773A ES 544773 A ES544773 A ES 544773A ES 8701177 A1 ES8701177 A1 ES 8701177A1
Authority
ES
Spain
Prior art keywords
formula
procedure
dina
piri
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES544773A
Other languages
English (en)
Other versions
ES544773A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kyorin Pharmaceutical Co Ltd
Original Assignee
Kyorin Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kyorin Pharmaceutical Co Ltd filed Critical Kyorin Pharmaceutical Co Ltd
Publication of ES544773A0 publication Critical patent/ES544773A0/es
Publication of ES8701177A1 publication Critical patent/ES8701177A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE PIRAZOL-1,5-APIRIDINA, DE FORMULA (I). COMPRENDE LA REACCION DE CONDENSACION DE UN COMPUESTO DE FORMULA (II) CON UN REACTIVO DE GRIGNARD, DE FORMULA XMGR3; SEGUIDA DE HIDROLISIS DEL PRODUCTO RESULTANTE PARA OBTENER EL COMPUESTO DE FORMULA (I), EN LA QUE R1 REPRESENTA C1-6; R2 ES HIDROGENO, ALQUILO O CICLOALQUILO C1-6; R3 ES ALQUILO C1-6 O ALILO, Y R5 ES HIDROGENO, METILO O METOXI. LA CONDENSACION SE LLEVA A CABO EN MEZCLA DE ETER ETILICO Y BENCENO SECOS, A TEMPERATURA PROXIMA A LA AMBIENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE ENFERMEDADES ALERGICAS.
ES544773A 1983-03-14 1985-07-01 Procedimiento para preparar derivados de pirazol-(1,5a)piri-dina Expired ES8701177A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP58041958A JPS59167590A (ja) 1983-03-14 1983-03-14 ピラゾロ〔１，５−ａ〕ピリジン誘導体、その製法及びそれを含有する治療剤

Publications (2)

Publication Number Publication Date
ES544773A0 ES544773A0 (es) 1986-11-16
ES8701177A1 true ES8701177A1 (es) 1986-11-16

Family

ID=12622693

Family Applications (3)

Application Number Title Priority Date Filing Date
ES530574A Expired ES8603474A1 (es) 1983-03-14 1984-03-14 Procedimiento para preparar derivados de pirazol 1,5-a-piridina
ES544773A Expired ES8701177A1 (es) 1983-03-14 1985-07-01 Procedimiento para preparar derivados de pirazol-(1,5a)piri-dina
ES552547A Expired ES8705439A1 (es) 1983-03-14 1986-02-28 Procedimiento para preparar derivados de pirazol-(1,5-a)piridina

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES530574A Expired ES8603474A1 (es) 1983-03-14 1984-03-14 Procedimiento para preparar derivados de pirazol 1,5-a-piridina

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES552547A Expired ES8705439A1 (es) 1983-03-14 1986-02-28 Procedimiento para preparar derivados de pirazol-(1,5-a)piridina

Country Status (10)

Country Link
US (1) US4578392A (es)
EP (1) EP0118916B1 (es)
JP (1) JPS59167590A (es)
KR (1) KR910001135B1 (es)
CA (1) CA1244434A (es)
DE (1) DE3465308D1 (es)
DK (1) DK160277C (es)
ES (3) ES8603474A1 (es)
HU (1) HU191249B (es)
NO (1) NO160442C (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01153633A (ja) * 1987-12-10 1989-06-15 Kyorin Pharmaceut Co Ltd 経皮吸収製剤
JPH01153634A (ja) * 1987-12-10 1989-06-15 Kyorin Pharmaceut Co Ltd 吸入剤
JPH0225418A (ja) * 1988-07-14 1990-01-26 Kyorin Pharmaceut Co Ltd イブジラスト脂肪乳剤およびその製造方法
TW200517114A (en) 2003-10-15 2005-06-01 Combinatorx Inc Methods and reagents for the treatment of immunoinflammatory disorders
AU2004292445B2 (en) 2003-11-21 2010-02-04 Zalicus Inc. Methods and reagents for the treatment of inflammatory disorders
RU2008122978A (ru) 2005-11-09 2009-12-20 Комбинаторкс, Инкорпорейтед (Us) Способы, композиции и наборы для лечения медицинских состояний
JP5352452B2 (ja) * 2006-06-06 2013-11-27 メディシノバ， インコーポレイテッド 置換ピラゾロ［１，５−ａ］ピリジン化合物およびその使用方法
WO2010021681A2 (en) * 2008-08-18 2010-02-25 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5154583A (en) * 1974-11-01 1976-05-13 Kyorin Seiyaku Kk Shinkipirazoro * 1 55a * pirijinjudotaino seizoho
US4097483A (en) * 1974-11-01 1978-06-27 Kyorin Pharmaceutical Co., Ltd. Pyrazolo 1,5-a!pyridines

Also Published As

Publication number Publication date
NO160442B (no) 1989-01-09
CA1244434A (en) 1988-11-08
ES530574A0 (es) 1985-12-16
DK160277C (da) 1991-07-22
ES552547A0 (es) 1987-05-01
DE3465308D1 (en) 1987-09-17
EP0118916A3 (en) 1985-06-05
KR840008152A (ko) 1984-12-13
NO160442C (no) 1989-04-19
EP0118916A2 (en) 1984-09-19
DK160277B (da) 1991-02-18
EP0118916B1 (en) 1987-08-12
ES544773A0 (es) 1986-11-16
DK136784D0 (da) 1984-02-29
NO840969L (no) 1984-09-17
US4578392A (en) 1986-03-25
JPH0559117B2 (es) 1993-08-30
DK136784A (da) 1984-09-15
JPS59167590A (ja) 1984-09-21
ES8705439A1 (es) 1987-05-01
HU191249B (en) 1987-01-28
ES8603474A1 (es) 1985-12-16
KR910001135B1 (ko) 1991-02-25

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970612