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ES8505211A1 - Mejoras introducidas en un metodo para la produccion de cefalosponica c. - Google Patents

Mejoras introducidas en un metodo para la produccion de cefalosponica c.

Info

Publication number
ES8505211A1
ES8505211A1 ES530294A ES530294A ES8505211A1 ES 8505211 A1 ES8505211 A1 ES 8505211A1 ES 530294 A ES530294 A ES 530294A ES 530294 A ES530294 A ES 530294A ES 8505211 A1 ES8505211 A1 ES 8505211A1
Authority
ES
Spain
Prior art keywords
cephalosporin
iii
phenyl
cephalosporium
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES530294A
Other languages
English (en)
Other versions
ES530294A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES8505211A1 publication Critical patent/ES8505211A1/es
Publication of ES530294A0 publication Critical patent/ES530294A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P35/00—Preparation of compounds having a 5-thia-1-azabicyclo [4.2.0] octane ring system, e.g. cephalosporin
    • C12P35/06—Cephalosporin C; Derivatives thereof

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Cephalosporin Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

PROCEDIMIENTO MEJORADO PARA PRODUCIR CEFALOSPORINA C.CONSISTE EN AGREGAR EN EL MEDIO NUTRITIVO DE CULTIVO DE UN MICROORGANISMO PRODUCTOR DE CEFALOSPORINA C COMO CEPHALOSPORIUM O CEPHALOSPORIUM ACREMONIUM, UN COMPUESTO DE FDRMULAS (I), (II), (III) O (IV) CON CONCENTRACIONES ENTRE 100 Y 3.000 PPM. SIENDO: R, R Y R INDEPENDIENTES ENTRE SI Y REPRESENTAN ALQUILO DE C 1 A 10 DE CADENA LINEAL O RAMIFICADA, FENILO O FENIL ALQUILO DE C 1 A 4; R, ALQUILO DE C 1 A 6 OPCIONALMENTE SUSTITUIDO POR GRUPOS HALOGENO, U -OR; R Y R, H O R; R, H, HIDROXI Y OTROS; R Y R, H O CL.
ES530294A 1983-03-07 1984-03-05 Mejoras introducidas en un metodo para la produccion de cefalosponica c. Granted ES530294A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/472,444 US4520101A (en) 1983-03-07 1983-03-07 Production of cephalosporin C

Publications (2)

Publication Number Publication Date
ES8505211A1 true ES8505211A1 (es) 1985-05-16
ES530294A0 ES530294A0 (es) 1985-05-16

Family

ID=23875534

Family Applications (1)

Application Number Title Priority Date Filing Date
ES530294A Granted ES530294A0 (es) 1983-03-07 1984-03-05 Mejoras introducidas en un metodo para la produccion de cefalosponica c.

Country Status (27)

Country Link
US (1) US4520101A (es)
JP (1) JPH069517B2 (es)
KR (1) KR910002861B1 (es)
AT (1) AT381723B (es)
AU (1) AU567142B2 (es)
BE (1) BE899086A (es)
CA (1) CA1209072A (es)
CH (1) CH661284A5 (es)
CY (1) CY1467A (es)
DE (1) DE3408194A1 (es)
DK (1) DK168451B1 (es)
ES (1) ES530294A0 (es)
FI (1) FI78733C (es)
FR (1) FR2545502B1 (es)
GB (1) GB2136000B (es)
GR (1) GR81804B (es)
HK (1) HK16189A (es)
IE (1) IE57096B1 (es)
IT (1) IT1175945B (es)
KE (1) KE3849A (es)
LU (1) LU85240A1 (es)
MY (1) MY8800129A (es)
NL (1) NL194830C (es)
PT (1) PT78205B (es)
SE (1) SE461470B (es)
SG (1) SG79688G (es)
ZA (1) ZA841602B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013053953A1 (en) * 2011-10-14 2013-04-18 Université de Liège Method for measuring beta-lactam antibiotics

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB820422A (en) * 1957-01-30 1959-09-23 Ici Ltd Production of cephalosporin by fermentation
US3151240A (en) * 1960-09-27 1964-09-29 Bendix Corp Carrier signal attenuation as a function of two variables
FR1363594A (fr) * 1962-07-02 1964-06-12 Merck & Co Inc Procédé de production de céphalosporine c par fermentation
GB975394A (en) * 1962-07-25 1964-11-18 Farmaceutici Italia Cephalosporin c
GB1109362A (en) * 1964-04-10 1968-04-10 Nat Res Dev Improvements in fermentation processes for the production of antibiotics from emericellopsis-cephalosporium fungi
US3573296A (en) * 1968-07-01 1971-03-30 Bristol Myers Co Process for the preparation of 7-aminocephalosporanic acid
CH553850A (de) * 1970-01-21 1974-09-13 Ciba Geigy Ag Verfahren zur darstellung von fuer die gesteuerte biosynthese von cephalosporin c, geeigneten mangel-mutanten und deren verwendung zur gesteuerten biosynthese von cephalosporin c.
GB1400433A (en) * 1971-08-13 1975-07-16 Alfa Farmaceutici Spa Production of cephalosporin c
JPS5431077B2 (es) * 1971-11-15 1979-10-04
US3830809A (en) * 1972-08-25 1974-08-20 Bristol Myers Co Bis-dicyclohexylamine n-carbisobutoxycephalosporin c
US4059573A (en) * 1973-08-01 1977-11-22 Glaxo Laboratories Limited Extraction of N-blocked amino acids from aqueous media
DK385974A (es) * 1973-08-17 1975-04-28 Ciba Geigy Ag
JPS577719B2 (es) * 1973-09-28 1982-02-12
JPS577720B2 (es) * 1973-10-01 1982-02-12
US3932392A (en) * 1974-01-14 1976-01-13 Bristol-Myers Company Process for the preparation of 7-aminocephalosporanic acids
IT1042829B (it) * 1975-09-24 1980-01-30 Lorenzini Sas Inst Biochim Procedimento per la produzione di cefalosporina c
US4178210A (en) * 1977-03-07 1979-12-11 Massachusetts Institute Of Technology Accellular synthesis of cephalosporins
CA1102264A (en) * 1977-03-07 1981-06-02 Arnold L. Demain Acellular synthesis of cephalosporins
JPS54163880A (en) * 1978-04-26 1979-12-26 Glaxo Group Ltd Improvement in cephalosporin production

Also Published As

Publication number Publication date
SE8401235D0 (sv) 1984-03-06
KR910002861B1 (ko) 1991-05-06
HK16189A (en) 1989-03-03
IE57096B1 (en) 1992-04-22
IT8419892A0 (it) 1984-03-02
FI78733B (fi) 1989-05-31
DK168451B1 (da) 1994-03-28
JPS59173097A (ja) 1984-09-29
BE899086A (fr) 1984-09-06
US4520101A (en) 1985-05-28
PT78205B (en) 1986-08-05
NL194830B (nl) 2002-12-02
GB2136000A (en) 1984-09-12
DE3408194C2 (es) 1991-06-27
KE3849A (en) 1989-03-31
MY8800129A (en) 1988-12-31
LU85240A1 (fr) 1984-11-14
NL8400691A (nl) 1984-10-01
DK139484A (da) 1984-09-08
KR840008167A (ko) 1984-12-13
CA1209072A (en) 1986-08-05
CH661284A5 (de) 1987-07-15
GR81804B (es) 1984-12-12
SE461470B (sv) 1990-02-19
NL194830C (nl) 2003-04-03
IT1175945B (it) 1987-08-12
AU567142B2 (en) 1987-11-12
FI78733C (fi) 1989-09-11
FR2545502A1 (fr) 1984-11-09
FI840838A7 (fi) 1984-09-08
FR2545502B1 (fr) 1986-10-17
FI840838A0 (fi) 1984-03-02
AU2447884A (en) 1984-09-13
SE8401235L (sv) 1984-09-08
GB2136000B (en) 1986-09-10
ATA74384A (de) 1986-04-15
GB8405879D0 (en) 1984-04-11
AT381723B (de) 1986-11-25
CY1467A (en) 1989-07-21
DK139484D0 (da) 1984-02-29
ES530294A0 (es) 1985-05-16
DE3408194A1 (de) 1985-04-18
IE840536L (en) 1984-09-07
JPH069517B2 (ja) 1994-02-09
ZA841602B (en) 1984-10-31
PT78205A (en) 1984-04-01
SG79688G (en) 1989-03-23
IT8419892A1 (it) 1985-09-02

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20050207