[go: up one dir, main page]

ES8406063A1 - Un procedimiento para la preparacion de una amida de un dipeptido l-aspartil-d-aminoacido. - Google Patents

Un procedimiento para la preparacion de una amida de un dipeptido l-aspartil-d-aminoacido.

Info

Publication number
ES8406063A1
ES8406063A1 ES521764A ES521764A ES8406063A1 ES 8406063 A1 ES8406063 A1 ES 8406063A1 ES 521764 A ES521764 A ES 521764A ES 521764 A ES521764 A ES 521764A ES 8406063 A1 ES8406063 A1 ES 8406063A1
Authority
ES
Spain
Prior art keywords
preparation
aminoacido
aspartil
amida
dipeptide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES521764A
Other languages
English (en)
Other versions
ES521764A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Corp Belgium
Pfizer Corp SRL
Original Assignee
Pfizer Corp Belgium
Pfizer Corp SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Corp Belgium, Pfizer Corp SRL filed Critical Pfizer Corp Belgium
Publication of ES521764A0 publication Critical patent/ES521764A0/es
Publication of ES8406063A1 publication Critical patent/ES8406063A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C07K5/06113—Asp- or Asn-amino acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/801—Peptide sweetners

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Seasonings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Apparatus For Radiation Diagnosis (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
  • Joints Allowing Movement (AREA)
  • Discharging, Photosensitive Material Shape In Electrophotography (AREA)
  • Manufacturing Of Electrical Connectors (AREA)
  • Coupling Device And Connection With Printed Circuit (AREA)
  • Detergent Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UNA AMIDA DE UN DEPEPTIDO L-ASPARTIL-D-AMINOACIDO.CONSIST E EN: A) HACER REACCIONAR UNA SAL DE ADICION DE ACIDO DEL ANHIDRIDO L-ASPARTICO DE FORMULA (II) CON UNA AMIDA DE UN D-AMINOACIDO DE FORMULA (III); Y B) CRISTALIZAR EL DIPEPTIDO L-ASPARTIL-D-AMINOACIDO RESULTANTE DE FORMULA (I) CON EL ACIDO SU/FONICO DE FORMULA (IV), DONDE A ES HIDROGENO O HIDROXI; Y R ES UN GRUPO DE FORMULA (V); UNO DE R, R, R Y R ES ALQUILO C 1 A 4 Y LOS RESTANTES HIDROGENO O ALQUILO C 1 A 4; X ES 0, S, SO, SO2, Y OTROS; M ES ), 1, 2, 3, O 4; N, P Y Q SON 0,1, 2 O 3, CON LA CONDICION QUE N B P NO SEA MAYOR QUE 3; R ES HIDROGENO, METILO O CLORO; Y R ES HIDROGENO O METILO.TIENE APLICACION POR SUS PROPIEDADES EDULCORANTES.
ES521764A 1981-09-08 1983-04-22 Un procedimiento para la preparacion de una amida de un dipeptido l-aspartil-d-aminoacido. Expired ES8406063A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/300,366 US4375430A (en) 1981-09-08 1981-09-08 Processes for preparation, isolation and purification of dipeptide sweeteners

Publications (2)

Publication Number Publication Date
ES521764A0 ES521764A0 (es) 1984-07-01
ES8406063A1 true ES8406063A1 (es) 1984-07-01

Family

ID=23158792

Family Applications (3)

Application Number Title Priority Date Filing Date
ES515545A Granted ES515545A0 (es) 1981-09-08 1982-09-07 "un procedimiento para la purificacion o aislamiento de una amida de un dipeptido l-aspartil-d-aminoacido".
ES521764A Expired ES8406063A1 (es) 1981-09-08 1983-04-22 Un procedimiento para la preparacion de una amida de un dipeptido l-aspartil-d-aminoacido.
ES521765A Granted ES521765A0 (es) 1981-09-08 1983-04-22 Un procedimiento para la preparacion de una amida de un dipeptido l-aspartil-d-aminoacido.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES515545A Granted ES515545A0 (es) 1981-09-08 1982-09-07 "un procedimiento para la purificacion o aislamiento de una amida de un dipeptido l-aspartil-d-aminoacido".

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES521765A Granted ES521765A0 (es) 1981-09-08 1983-04-22 Un procedimiento para la preparacion de una amida de un dipeptido l-aspartil-d-aminoacido.

Country Status (19)

Country Link
US (1) US4375430A (es)
EP (1) EP0074249B1 (es)
JP (1) JPS5857350A (es)
AT (1) ATE8879T1 (es)
AU (1) AU534082B2 (es)
CA (1) CA1238903A (es)
DE (1) DE3260543D1 (es)
DK (1) DK155947C (es)
ES (3) ES515545A0 (es)
FI (1) FI76352C (es)
GR (1) GR76704B (es)
IE (1) IE53795B1 (es)
IL (1) IL66739A (es)
MX (1) MX155762A (es)
NO (1) NO161123C (es)
NZ (1) NZ201816A (es)
PT (1) PT75519B (es)
YU (1) YU43277B (es)
ZA (1) ZA826522B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4855454A (en) * 1980-01-21 1989-08-08 Pfizer Inc. Branched amides of L-aspartyl-D-amino acid dipeptides
US4465626A (en) * 1981-09-08 1984-08-14 Pfizer Inc. Process for preparation, isolation and purification of dipeptide sweeteners
CA1276394C (en) * 1984-07-13 1990-11-13 John M. Janusz Alpha-l-aspartyl-d-phenylglycine esters and amides useful as high intensity sweeteners
CA1276395C (en) * 1984-07-13 1990-11-13 John M. Janusz Oxa-fenchyl esters and amides of alpha-l-aspartyl-d- phenylglycine
EP0199257A3 (en) * 1985-04-15 1988-08-10 General Foods Corporation L-aminodicarboxylic acid esters and an edible composition containing same as sweeteners
US4572799A (en) * 1985-04-15 1986-02-25 General Foods Corporation L-Aminodicarboxylic acid amides
US4935355A (en) * 1986-04-15 1990-06-19 Synthetech, Inc. Preparation of dipeptides
US4758443A (en) * 1986-06-18 1988-07-19 General Foods Corporation Thietanyl-substituted amides and use thereof as sweeteners
US4855455A (en) * 1988-01-22 1989-08-08 W. R. Grace & Co.-Conn. Preparation of amino acid derivatives
US5283357A (en) * 1988-03-14 1994-02-01 Mitsui Toatsu Chemicals, Incorporated Separation method of α-l-aspartyl-l-phenylalanine methyl ester
DE502005007959D1 (de) * 2004-10-14 2009-10-01 Wilex Ag Verfahren zur reinigung von 3-hydroxy-amidino-phenylalanin-derivaten durch ausfällung und umkristallisation eines salzes mit einer aromatischen sulfonsäure

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA909254A (en) * 1969-12-30 1972-09-05 Ariyoshi Yasuo METHOD OF PURIFYING LOWER ALKYL OF .alpha.-L-ASPARTYL-L-PHENYLALANINE

Also Published As

Publication number Publication date
CA1238903A (en) 1988-07-05
FI76352B (fi) 1988-06-30
IL66739A0 (en) 1982-12-31
EP0074249B1 (en) 1984-08-08
ES8406064A1 (es) 1984-07-01
ATE8879T1 (de) 1984-08-15
DK155947C (da) 1989-11-13
PT75519A (en) 1982-10-01
EP0074249A1 (en) 1983-03-16
FI76352C (fi) 1988-10-10
MX155762A (es) 1988-04-25
DE3260543D1 (en) 1984-09-13
ES521764A0 (es) 1984-07-01
NO161123B (no) 1989-03-28
DK155947B (da) 1989-06-05
JPS5857350A (ja) 1983-04-05
FI823072A0 (fi) 1982-09-06
ES8308304A1 (es) 1983-08-16
YU43277B (en) 1989-06-30
NO161123C (no) 1989-07-05
JPS6318959B2 (es) 1988-04-20
ZA826522B (en) 1983-07-27
IL66739A (en) 1985-07-31
IE53795B1 (en) 1989-02-15
PT75519B (en) 1985-11-25
DK399182A (da) 1983-03-09
AU534082B2 (en) 1984-01-05
US4375430A (en) 1983-03-01
YU201382A (en) 1985-04-30
IE822175L (en) 1983-03-08
NO823002L (no) 1983-03-09
ES515545A0 (es) 1983-08-16
GR76704B (es) 1984-08-29
AU8808782A (en) 1983-05-05
NZ201816A (en) 1985-05-31
ES521765A0 (es) 1984-07-01
FI823072L (fi) 1983-03-09

Similar Documents

Publication Publication Date Title
ES8406063A1 (es) Un procedimiento para la preparacion de una amida de un dipeptido l-aspartil-d-aminoacido.
DK600483D0 (da) Fremgangsmade til fremstilling af phosphonomethylerede aminosyrer
SE8502315L (sv) Forbettrat transamineringsforfarande for framstellning av aminosyror
ES2032052T3 (es) Procedimiento para la obtencion de n,n-(dibenzohexatrienilen) ureas.
JPS5218886A (en) Production of amino acids by fermentation process
AR241137A2 (es) "procedimiento para preparar beta-metilen-2 o 3-tiofenetanamina".
ES2066413T3 (es) Procedimiento para la purificacion de n,n-dietilmandelamida.
AR240829A2 (es) Procedimiento para aislar levamisol de tetramisol
FR2584719B1 (fr) Procede de preparation des derives n-methyles du lysergol et du methoxy-10a lumilysergol
JPS523899A (en) Method of concentrating food solution
ES2000879A6 (es) Un procedimiento para preparar una sal de acido inorganico de cloruro de n-(1(s)-etoxicarbonil-3-fenilpropil)-l-alanilo
ES8103042A1 (es) Un procedimiento para preparar lactamas biciclicas
FI871761A7 (fi) Menetelmä L-aminohappojen valmistamiseksi transaminaation avulla.
ES8303330A1 (es) "procedimiento de preparacion del n-(1-propil-2-pirrolidinilmetil)-2-metoxi-5-sulfamoil-benzamida".
JPS52136190A (en) Purification of cephalosporin derivatives
ES524265A0 (es) Procedimiento para la obtencion de la n- (acido-2-amino-4-(metiltio) butirico) amida del acido (2-fenil)butirico.
JPS52100421A (en) Purification of glutathione
JPS53146800A (en) Polybenzimidazolone having pendant sulfonic acid groups, its preparation and selective permeable membranes
JPS51138646A (en) Process for purification of styrene sulfonic metal salt
JPS52154593A (en) Preparation of l-sulfur-containing amino acid
SE8200835L (en) Frame for house boat - has detachable transportable sections and pontoons, assembled laterally using fixtures

Legal Events

Date Code Title Description
PC1A Transfer granted