ES8402809A1 - Procedimiento para la preparacion de carbaciclinas. - Google Patents
Procedimiento para la preparacion de carbaciclinas.Info
- Publication number
- ES8402809A1 ES8402809A1 ES522632A ES522632A ES8402809A1 ES 8402809 A1 ES8402809 A1 ES 8402809A1 ES 522632 A ES522632 A ES 522632A ES 522632 A ES522632 A ES 522632A ES 8402809 A1 ES8402809 A1 ES 8402809A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- chem
- free
- carbon atoms
- functionally modified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/005—Analogues or derivatives having the five membered ring replaced by other rings
- C07C405/0075—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system
- C07C405/0083—Analogues or derivatives having the five membered ring replaced by other rings having the side-chains or their analogues or derivatives attached to a condensed ring system which is only ortho or peri condensed, e.g. carbacyclins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Polyesters Or Polycarbonates (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Indole Compounds (AREA)
- Saccharide Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Road Signs Or Road Markings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE CARBACICLINAS, DE FORMULA GENERAL (I).CONSISTE EN ESTERIFICAR, EN PRESENCIA DE UNA BASE, UN COMPUESTO DE FORMULA (II), EN LA QUE R2, R3, X, A, W, D Y E TIENEN LOS SIGNIFICADOS YA MENCIONADOS, CON UNA BVB-HALOGENOCETONA, DE FORMULA GENERAL (III), EN LA QUE R1 TIENE EL SIGNIFICADO YA MENCIONADO; Y HAL REPRESENTA LOS HALOGENOS CL O BR.DE APLICACION EN EL TRATAMIENTO TERAPEUTICO DE ANIMALES MAMIFEROS, INCLUIDO EL HOMBRE.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823221193 DE3221193A1 (de) | 1982-05-28 | 1982-05-28 | Neue carbacyclinester, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8402809A1 true ES8402809A1 (es) | 1984-03-01 |
| ES522632A0 ES522632A0 (es) | 1984-03-01 |
Family
ID=6165375
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES522632A Granted ES522632A0 (es) | 1982-05-28 | 1983-05-23 | Procedimiento para la preparacion de carbaciclinas. |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US4618626A (es) |
| EP (1) | EP0099850B1 (es) |
| JP (1) | JPS58225041A (es) |
| AT (1) | ATE70531T1 (es) |
| AU (1) | AU567877B2 (es) |
| CA (1) | CA1246557A (es) |
| CS (1) | CS240962B2 (es) |
| DD (1) | DD209806A5 (es) |
| DE (2) | DE3221193A1 (es) |
| DK (1) | DK207383A (es) |
| ES (1) | ES522632A0 (es) |
| FI (1) | FI831890L (es) |
| GR (1) | GR77466B (es) |
| HU (1) | HU190722B (es) |
| IE (1) | IE58301B1 (es) |
| IL (1) | IL68715A0 (es) |
| NO (1) | NO831908L (es) |
| ZA (1) | ZA833883B (es) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3225288A1 (de) * | 1982-07-02 | 1984-01-19 | Schering AG, 1000 Berlin und 4709 Bergkamen | Neue carbacycline, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| US4876279A (en) * | 1986-05-05 | 1989-10-24 | Merck & Co., Inc. | Antihypercholesterolemic compounds |
| GB2192395B (en) * | 1986-07-08 | 1990-11-14 | Kotobuki Seiyaku Co Ltd | Carbacyclin derivatives |
| US4730078A (en) * | 1987-05-13 | 1988-03-08 | G. D. Searle & Co. | Allenic prostacyclins |
| EP0410652B1 (en) * | 1989-07-27 | 1995-05-17 | Kabushiki Kaisha Ueno Seiyaku Oyo Kenkyujo | Use of 15-keto-prostanoic acid derivatives in the manufacture of a medicament for improvement of excretion of potassium ion |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3979440A (en) * | 1974-08-14 | 1976-09-07 | The Upjohn Company | Phenacyl-type esters of phenyl-substituted PGE-type compounds |
| US4705806A (en) * | 1978-02-13 | 1987-11-10 | Morton Jr Douglas R | Prostacyclin analogs |
| US4238414A (en) * | 1978-02-13 | 1980-12-09 | The Upjohn Company | 2-Decarboxy-2-aminomethyl-6a-carba-PGI2 compounds |
| DE3104044A1 (de) * | 1981-02-02 | 1982-08-26 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Neue prostacyclin-derivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
| GR77976B (es) * | 1982-03-12 | 1984-09-25 | Schering Ag |
-
1982
- 1982-05-28 DE DE19823221193 patent/DE3221193A1/de not_active Withdrawn
-
1983
- 1983-05-10 DK DK207383A patent/DK207383A/da not_active Application Discontinuation
- 1983-05-17 IL IL68715A patent/IL68715A0/xx unknown
- 1983-05-20 AU AU14813/83A patent/AU567877B2/en not_active Ceased
- 1983-05-20 DD DD83251139A patent/DD209806A5/de unknown
- 1983-05-23 ES ES522632A patent/ES522632A0/es active Granted
- 1983-05-25 CS CS833698A patent/CS240962B2/cs unknown
- 1983-05-26 JP JP58091648A patent/JPS58225041A/ja active Granted
- 1983-05-26 GR GR71466A patent/GR77466B/el unknown
- 1983-05-26 FI FI831890A patent/FI831890L/fi not_active Application Discontinuation
- 1983-05-26 IE IE124283A patent/IE58301B1/en not_active IP Right Cessation
- 1983-05-27 AT AT83730052T patent/ATE70531T1/de not_active IP Right Cessation
- 1983-05-27 DE DE8383730052T patent/DE3382479D1/de not_active Expired - Lifetime
- 1983-05-27 EP EP83730052A patent/EP0099850B1/en not_active Expired - Lifetime
- 1983-05-27 ZA ZA833883A patent/ZA833883B/xx unknown
- 1983-05-27 NO NO831908A patent/NO831908L/no unknown
- 1983-05-27 HU HU831891A patent/HU190722B/hu unknown
- 1983-05-27 CA CA000429033A patent/CA1246557A/en not_active Expired
-
1985
- 1985-09-16 US US06/777,535 patent/US4618626A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HU190722B (en) | 1986-10-28 |
| CS369883A2 (en) | 1985-06-13 |
| AU567877B2 (en) | 1987-12-10 |
| JPS58225041A (ja) | 1983-12-27 |
| ZA833883B (en) | 1984-04-25 |
| US4618626A (en) | 1986-10-21 |
| DE3221193A1 (de) | 1983-12-01 |
| IL68715A0 (en) | 1983-09-30 |
| EP0099850B1 (en) | 1991-12-18 |
| ATE70531T1 (de) | 1992-01-15 |
| DE3382479D1 (de) | 1992-01-30 |
| CA1246557A (en) | 1988-12-13 |
| FI831890A7 (fi) | 1983-11-29 |
| NO831908L (no) | 1983-11-29 |
| FI831890A0 (fi) | 1983-05-26 |
| ES522632A0 (es) | 1984-03-01 |
| DK207383A (da) | 1983-11-29 |
| IE831242L (en) | 1983-11-28 |
| JPH0355461B2 (es) | 1991-08-23 |
| AU1481383A (en) | 1983-12-01 |
| GR77466B (es) | 1984-09-24 |
| DD209806A5 (de) | 1984-05-23 |
| IE58301B1 (en) | 1993-10-06 |
| FI831890L (fi) | 1983-11-29 |
| CS240962B2 (en) | 1986-03-13 |
| EP0099850A1 (en) | 1984-02-01 |
| DK207383D0 (da) | 1983-05-10 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES8300090A1 (es) | "procedimiento para la preparacion de derivados de carbaciclina". | |
| IE870586L (en) | Cyclodextrin clathrates of carbacyclin derivatives. | |
| ES8402809A1 (es) | Procedimiento para la preparacion de carbaciclinas. | |
| ES8304056A1 (es) | "procedimiento para la preparacion de derivados de carbaciclina". | |
| EP0069049A3 (en) | Delta-8,9-prostaglandin derivatives, process for their preparation and their use as medicaments | |
| ZA85985B (en) | Novel carbacyclins,process for the preparation thereof,and their use as medicinal agents | |
| GR3002075T3 (en) | 4-hydroxy-4-(substituted alkenyl)-cyclohexane carboxylic acid |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19970519 |