ES8402659A1 - Procedimiento para determinar un ligando en una muestra de analisis liquida. - Google Patents
Procedimiento para determinar un ligando en una muestra de analisis liquida.Info
- Publication number
- ES8402659A1 ES8402659A1 ES518738A ES518738A ES8402659A1 ES 8402659 A1 ES8402659 A1 ES 8402659A1 ES 518738 A ES518738 A ES 518738A ES 518738 A ES518738 A ES 518738A ES 8402659 A1 ES8402659 A1 ES 8402659A1
- Authority
- ES
- Spain
- Prior art keywords
- specific binding
- binding assay
- ligand
- homogeneous specific
- labels
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000159 protein binding assay Methods 0.000 title abstract 4
- 230000009870 specific binding Effects 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 238000004458 analytical method Methods 0.000 title 1
- 239000003446 ligand Substances 0.000 abstract 4
- 102000004190 Enzymes Human genes 0.000 abstract 3
- 108090000790 Enzymes Proteins 0.000 abstract 3
- 230000027455 binding Effects 0.000 abstract 2
- 239000000427 antigen Substances 0.000 abstract 1
- 102000036639 antigens Human genes 0.000 abstract 1
- 108091007433 antigens Proteins 0.000 abstract 1
- 239000003153 chemical reaction reagent Substances 0.000 abstract 1
- -1 e.g. Substances 0.000 abstract 1
- 230000005670 electromagnetic radiation Effects 0.000 abstract 1
- 239000007788 liquid Substances 0.000 abstract 1
- 239000011159 matrix material Substances 0.000 abstract 1
- 239000007787 solid Substances 0.000 abstract 1
- 239000000758 substrate Substances 0.000 abstract 1
- 230000000007 visual effect Effects 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Finger-Pressure Massage (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Steroid Compounds (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Adhesives Or Adhesive Processes (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
PROCEDIMIENTO PARA DETERMINAR UN LIGANDO EN UNA MUESTRA DE ANALISIS LIQUIDA.COMPRENDE LAS ETAPAS DE: A) PONER EN CONTACTO LA MUESTRA CON UN DISPOSITIVO DE ENSAYO QUE COMPRENDE UN ELEMENTO SOPORTE SOLIDO INCORPORADO CON UN ASOCIADO DE LIGACION PARA DICHO LIGANDO Y CON UN CONJUGADO DEL LIQUIDO, O UN ANALOGO DE LIGACION DEL MISMO, QUIMICAMENTE ACOPLADO CON UN AGENTE MARCADOR SIENDO DETECTABLE EL AGENTE MARCADOR POR UNA SEÑAL ELECTROMAGNETICA QUE ES DISTINGUIBLE CUANDO EL CONJUGADO MARCADO ES LIGADO POR EL ASOCIADO DE LIGACION EN COMPARACION CUANDO NO ESLIGADO DE ESTE MODO Y B) MEDIR DICHA SEÑAL SOBRE EL ELEMENTO SOPORTE SIN SEPARAR FISICAMENTE EL CONJUGADO MARCADO QUE ESTA LIGADO POR EL ASOCIADO DE LIGACION DEL CONJUGADO MARCADO QUE ESTA LIGADO POR EL ASOCIADO DE LIGACION DEL CONJUGADO MARCADO QUE ESTA SIN LIGAR.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20237880A | 1980-10-30 | 1980-10-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES518738A0 ES518738A0 (es) | 1984-02-01 |
| ES8402659A1 true ES8402659A1 (es) | 1984-02-01 |
Family
ID=22749630
Family Applications (6)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES506689A Expired ES8305498A1 (es) | 1980-10-30 | 1981-10-29 | Perfeccionamientos en dispositivos de ensayo para determinar un ligante en una muestra liquida. |
| ES518737A Granted ES518737A0 (es) | 1980-10-30 | 1982-12-31 | Procedimiento de lignificacion para preparar un dispositivo de ensayo de analisis de ligacion especifica homogeneo. |
| ES518735A Expired ES8402657A1 (es) | 1980-10-30 | 1982-12-31 | Procedimiento de incorporacion multiple para preparar un dispositivo de ensayo de analisis de ligacion especifica homogeneo. |
| ES518738A Expired ES8402659A1 (es) | 1980-10-30 | 1982-12-31 | Procedimiento para determinar un ligando en una muestra de analisis liquida. |
| ES518739A Expired ES8402660A1 (es) | 1980-10-30 | 1982-12-31 | Perfeccionamientos en dispositivos de ensayo analiticos de capas multiples para detectar un ligando en una muestra liquida. |
| ES518736A Granted ES518736A0 (es) | 1980-10-30 | 1982-12-31 | Procedimiento de complejo preformado para la preparacion de un dispositivo de ensayo de analisis de ligacion especifica homogeneo. |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES506689A Expired ES8305498A1 (es) | 1980-10-30 | 1981-10-29 | Perfeccionamientos en dispositivos de ensayo para determinar un ligante en una muestra liquida. |
| ES518737A Granted ES518737A0 (es) | 1980-10-30 | 1982-12-31 | Procedimiento de lignificacion para preparar un dispositivo de ensayo de analisis de ligacion especifica homogeneo. |
| ES518735A Expired ES8402657A1 (es) | 1980-10-30 | 1982-12-31 | Procedimiento de incorporacion multiple para preparar un dispositivo de ensayo de analisis de ligacion especifica homogeneo. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES518739A Expired ES8402660A1 (es) | 1980-10-30 | 1982-12-31 | Perfeccionamientos en dispositivos de ensayo analiticos de capas multiples para detectar un ligando en una muestra liquida. |
| ES518736A Granted ES518736A0 (es) | 1980-10-30 | 1982-12-31 | Procedimiento de complejo preformado para la preparacion de un dispositivo de ensayo de analisis de ligacion especifica homogeneo. |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0051213B1 (es) |
| JP (1) | JPS57103055A (es) |
| AT (1) | ATE26187T1 (es) |
| AU (1) | AU530707B2 (es) |
| CA (1) | CA1183450A (es) |
| DE (1) | DE3176039D1 (es) |
| DK (1) | DK157328C (es) |
| ES (6) | ES8305498A1 (es) |
| FI (1) | FI75677C (es) |
| GR (1) | GR82308B (es) |
| IE (1) | IE52848B1 (es) |
| IL (1) | IL63333A (es) |
| NO (1) | NO161703C (es) |
| ZA (1) | ZA814949B (es) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4390343A (en) * | 1981-07-06 | 1983-06-28 | Miles Laboratories, Inc. | Multilayer analytical element having an impermeable radiation diffusing and blocking layer |
| US4468469A (en) * | 1981-11-04 | 1984-08-28 | Miles Laboratories, Inc. | Substituted phenylacetic acids and salts as TBP blocking agents in iodothyronine immunoassays |
| DE3362399D1 (en) * | 1982-05-24 | 1986-04-10 | Miles Lab | Improved homogeneous binding assay method and reagent system, test kit and test device therefor |
| US4435504A (en) * | 1982-07-15 | 1984-03-06 | Syva Company | Immunochromatographic assay with support having bound "MIP" and second enzyme |
| US4622293A (en) * | 1983-07-05 | 1986-11-11 | Miles Laboratories, Inc. | Iodothyronine immunoassays employing HMS as TBP blocking agent |
| JPH0672884B2 (ja) * | 1985-10-17 | 1994-09-14 | コニカ株式会社 | 分析素子 |
| JPH0672885B2 (ja) * | 1985-10-17 | 1994-09-14 | コニカ株式会社 | 分析素子 |
| US5763262A (en) * | 1986-09-18 | 1998-06-09 | Quidel Corporation | Immunodiagnostic device |
| JPS63133065A (ja) * | 1986-11-25 | 1988-06-04 | Konica Corp | 生物活性物質の安定化方法 |
| JPH01280253A (ja) * | 1988-01-28 | 1989-11-10 | Konica Corp | 免疫学的多層分析素子及び分析方法 |
| US5059522A (en) * | 1988-08-18 | 1991-10-22 | Wayne Lawrence G | Intrinsic enzyme dot blot immunoassay or indentification of microorganisms |
| DE4422884A1 (de) * | 1994-06-30 | 1996-01-04 | Merck Patent Gmbh | Feststoffverdünnte Standards und Verfahren zur Herstellung einer Standardlösung |
| US6315264B1 (en) | 1999-02-05 | 2001-11-13 | Gerald Baker | Fast-closing stepping actuator for a valve member |
| US6152167A (en) * | 1999-02-11 | 2000-11-28 | Cooper Cameron | Valve actuator with emergency shutdown feature |
| JP4896869B2 (ja) | 2005-03-03 | 2012-03-14 | 積水メディカル株式会社 | 免疫測定法及びその試薬 |
| DE102006009516B4 (de) * | 2006-02-28 | 2007-12-06 | Analyticon Biotechnologies Ag | Testvorrichtung, Herstellungsverfahren dafür und Testverfahren |
| JP7286070B2 (ja) * | 2021-01-31 | 2023-06-05 | 株式会社バランス・イースト | 検査システム、検査方法、プログラム、およびコンピュータが読み取り可能な記憶媒体 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3641235A (en) * | 1968-11-01 | 1972-02-08 | Miles Lab | Immunological reagent and process for making same |
| IT1006557B (it) * | 1971-09-08 | 1976-10-20 | Bagshawe Kenneth Dawson | Cella di reazione particolarmente utile in prove di radioimmunita |
| SE388694B (sv) * | 1975-01-27 | 1976-10-11 | Kabi Ab | Sett att pavisa ett antigen exv i prov av kroppvetskor, med utnyttjande av till porost berarmaterial bundna eller adsorberande antikroppar |
| IN142734B (es) * | 1975-04-28 | 1977-08-20 | Miles Lab | |
| US4094647A (en) * | 1976-07-02 | 1978-06-13 | Thyroid Diagnostics, Inc. | Test device |
| DE2733380A1 (de) * | 1977-07-23 | 1979-02-08 | Behringwerke Ag | Immunologisches analysenverfahren |
| US4160008A (en) * | 1978-01-26 | 1979-07-03 | Miles Laboratories, Inc. | Multilayered test device for determining the presence of a liquid sample component, and method of use |
| AU531777B2 (en) * | 1978-04-05 | 1983-09-08 | Syva Co. | Label/solid conjugate immunoassay system |
| DE2924249C2 (de) * | 1978-06-22 | 1989-04-27 | Miles, Inc., Elkhart, Ind., Us | Spezifische bindungs-untersuchungsmethode zur bestimmung eines liganden in einem fluessigen medium und reagentien zur durchfuehrung dieser methode |
| US4258001A (en) * | 1978-12-27 | 1981-03-24 | Eastman Kodak Company | Element, structure and method for the analysis or transport of liquids |
| FR2458070A1 (fr) * | 1979-05-28 | 1980-12-26 | Compiegne Inst Technol Surf Ac | Dispositif pour l'identification et le dosage de substances biochimiques antigeniques dans les fluides biologiques |
-
1981
- 1981-07-14 CA CA000381675A patent/CA1183450A/en not_active Expired
- 1981-07-16 IL IL63333A patent/IL63333A/xx not_active IP Right Cessation
- 1981-07-20 ZA ZA814949A patent/ZA814949B/xx unknown
- 1981-09-08 AU AU75047/81A patent/AU530707B2/en not_active Ceased
- 1981-10-15 NO NO813483A patent/NO161703C/no unknown
- 1981-10-22 AT AT81108681T patent/ATE26187T1/de not_active IP Right Cessation
- 1981-10-22 EP EP81108681A patent/EP0051213B1/en not_active Expired
- 1981-10-22 DE DE8181108681T patent/DE3176039D1/de not_active Expired
- 1981-10-28 FI FI813369A patent/FI75677C/fi not_active IP Right Cessation
- 1981-10-29 ES ES506689A patent/ES8305498A1/es not_active Expired
- 1981-10-29 IE IE2537/81A patent/IE52848B1/en not_active IP Right Cessation
- 1981-10-29 JP JP56172169A patent/JPS57103055A/ja active Granted
- 1981-10-29 DK DK478481A patent/DK157328C/da not_active IP Right Cessation
- 1981-10-29 GR GR66379A patent/GR82308B/el unknown
-
1982
- 1982-12-31 ES ES518737A patent/ES518737A0/es active Granted
- 1982-12-31 ES ES518735A patent/ES8402657A1/es not_active Expired
- 1982-12-31 ES ES518738A patent/ES8402659A1/es not_active Expired
- 1982-12-31 ES ES518739A patent/ES8402660A1/es not_active Expired
- 1982-12-31 ES ES518736A patent/ES518736A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| NO813483L (no) | 1982-05-03 |
| FI75677B (fi) | 1988-03-31 |
| ES518739A0 (es) | 1984-02-01 |
| ES8402662A1 (es) | 1984-02-01 |
| IE812537L (en) | 1982-04-30 |
| ES518735A0 (es) | 1984-02-01 |
| ES8402657A1 (es) | 1984-02-01 |
| FI813369L (fi) | 1982-05-01 |
| ES8402658A1 (es) | 1984-02-01 |
| GR82308B (es) | 1984-12-13 |
| ES518738A0 (es) | 1984-02-01 |
| ES506689A0 (es) | 1983-04-01 |
| DK478481A (da) | 1982-05-01 |
| ES518736A0 (es) | 1984-02-01 |
| JPH0235261B2 (es) | 1990-08-09 |
| DK157328B (da) | 1989-12-11 |
| AU530707B2 (en) | 1983-07-28 |
| ES8402660A1 (es) | 1984-02-01 |
| IL63333A0 (en) | 1981-10-30 |
| EP0051213A1 (en) | 1982-05-12 |
| DK157328C (da) | 1990-05-07 |
| NO161703C (no) | 1989-09-13 |
| JPS57103055A (en) | 1982-06-26 |
| ATE26187T1 (de) | 1987-04-15 |
| EP0051213B1 (en) | 1987-03-25 |
| CA1183450A (en) | 1985-03-05 |
| FI75677C (fi) | 1988-07-11 |
| NO161703B (no) | 1989-06-05 |
| IL63333A (en) | 1986-01-31 |
| AU7504781A (en) | 1982-06-10 |
| ZA814949B (en) | 1982-09-29 |
| IE52848B1 (en) | 1988-03-30 |
| ES518737A0 (es) | 1984-02-01 |
| DE3176039D1 (en) | 1987-04-30 |
| ES8305498A1 (es) | 1983-04-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19961130 |