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ES8308326A1 - Procedimiento para la preparacion de amidobenzamidas. - Google Patents

Procedimiento para la preparacion de amidobenzamidas.

Info

Publication number
ES8308326A1
ES8308326A1 ES513792A ES513792A ES8308326A1 ES 8308326 A1 ES8308326 A1 ES 8308326A1 ES 513792 A ES513792 A ES 513792A ES 513792 A ES513792 A ES 513792A ES 8308326 A1 ES8308326 A1 ES 8308326A1
Authority
ES
Spain
Prior art keywords
group
amidobenzamides
procedure
preparation
pyridyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES513792A
Other languages
English (en)
Other versions
ES513792A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi SA
Original Assignee
Sanofi SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8113420A external-priority patent/FR2509305B1/fr
Priority claimed from FR8119967A external-priority patent/FR2515181A1/fr
Priority claimed from FR8123084A external-priority patent/FR2518097A1/fr
Application filed by Sanofi SA filed Critical Sanofi SA
Publication of ES513792A0 publication Critical patent/ES513792A0/es
Publication of ES8308326A1 publication Critical patent/ES8308326A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE AMIDOBENZAMIDAS. SE HACE REACCIONAR LA 2-(5-DIMETILAMINOMETILFURAN-2-ILMETILTIO) ETILAMINA CON UN DERIVADO FUNCIONAL DE UN ACIDO BENZOICO DE FORMULA GENERAL (II), EN UN DISOLVENTE ORGANICO A UNA TEMPERATURA COMPRENDIDA ENTRE 0 C Y LA DE EBULLICION DEL DISOLVENTE UTILIZADO. EL PRODUCTO OBTENIDO (I) SE TRANSFORMA EN LAS SALES CORRESPONDIENTES FARMACEUTICAMENTE ACEPTABLES. A REPRESENTA EL GRUPO CO O SO<2 Y B ES UN GRUPO ALQUILO CON 1 A 6 ATOMOS DE CARBONO, UN GRUPO FENILO, UN GRUPO PIRIDILO, UN GRUPO PIRIDILO 1-OXIDO UN GRUPO PIRAZINILO O UN GRUPO TIENILO.
ES513792A 1981-07-08 1982-07-07 Procedimiento para la preparacion de amidobenzamidas. Expired ES8308326A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR8113420A FR2509305B1 (fr) 1981-07-08 1981-07-08 Benzamides, procede pour leur preparation et compositions pharmaceutiques les renfermant
FR8119967A FR2515181A1 (fr) 1981-10-23 1981-10-23 Amidobenzamides, procede pour leur preparation et compositions pharmaceutiques les renfermant
FR8123084A FR2518097A1 (fr) 1981-12-10 1981-12-10 Amidobenzamide, procede pour sa preparation et compositions pharmaceutiques la renfermant

Publications (2)

Publication Number Publication Date
ES513792A0 ES513792A0 (es) 1983-08-16
ES8308326A1 true ES8308326A1 (es) 1983-08-16

Family

ID=27251063

Family Applications (1)

Application Number Title Priority Date Filing Date
ES513792A Expired ES8308326A1 (es) 1981-07-08 1982-07-07 Procedimiento para la preparacion de amidobenzamidas.

Country Status (17)

Country Link
US (1) US4439444A (es)
EP (1) EP0069664B1 (es)
AR (1) AR231288A1 (es)
AU (1) AU547405B2 (es)
CA (1) CA1190927A (es)
DD (1) DD202433A5 (es)
DE (1) DE3262870D1 (es)
DK (1) DK305982A (es)
ES (1) ES8308326A1 (es)
FI (1) FI822408A7 (es)
GR (1) GR76007B (es)
HU (1) HU189599B (es)
IL (1) IL66227A (es)
NO (1) NO822122L (es)
NZ (1) NZ201197A (es)
PT (1) PT75209B (es)
YU (1) YU149482A (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2531706A1 (fr) * 1982-08-13 1984-02-17 Sanofi Sa Benzamides, leurs sels, procede pour leur preparation et compositions pharmaceutiques les renfermant
GB8422461D0 (en) * 1984-09-05 1984-10-10 Wyeth John & Brother Ltd Pyridine derivatives
US4912101A (en) * 1987-03-13 1990-03-27 Fujirebio Kabushiki Kaisha 4-aminomethyl-pyridyl-2-oxy derivatives having anti-ulcer activity
GB8921792D0 (en) * 1989-09-27 1989-11-08 May & Baker Ltd New compositions of matter
EP0673925A4 (en) * 1992-11-20 1996-04-03 Kaken Pharma Co Ltd ACETAMIDE DERIVATIVES.
NZ565255A (en) * 2005-06-22 2010-04-30 Plexxikon Inc Pyrrolo[2,3-b] pyridine derivatives as protein kinase inhibitors
WO2008063888A2 (en) 2006-11-22 2008-05-29 Plexxikon, Inc. Compounds modulating c-fms and/or c-kit activity and uses therefor
AU2010232670B2 (en) 2009-04-03 2015-07-09 F. Hoffmann-La Roche Ag Propane- I-sulfonic acid {3- [5- (4 -chloro-phenyl) -1H-pyrrolo [2, 3-b] pyridine-3-carbonyl] -2, 4-difluoro-pheny l } -amide compositions and uses thereof
US8329724B2 (en) 2009-08-03 2012-12-11 Hoffmann-La Roche Inc. Process for the manufacture of pharmaceutically active compounds
MA33975B1 (fr) 2009-11-06 2013-02-01 Plexxikon Inc Composés et méthodes de modulation des kinases et leurs indications d'emploi
HUE040136T2 (hu) 2011-02-07 2019-02-28 Plexxikon Inc Vegyületek és eljárások kináz modulációra és azok indikációi
US9150570B2 (en) 2012-05-31 2015-10-06 Plexxikon Inc. Synthesis of heterocyclic compounds
EP4196793A1 (en) 2020-08-11 2023-06-21 Université de Strasbourg H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2835695A1 (de) * 1977-08-29 1979-03-15 Yamanouchi Pharma Co Ltd Neue heterocyclische verbindungen, verfahren zu ihrer herstellung und arzneimittel, die diese enthalten
JPS5681578A (en) * 1979-12-07 1981-07-03 Shionogi & Co Ltd Novel thioalkyl amide derivative

Also Published As

Publication number Publication date
CA1190927A (en) 1985-07-23
DK305982A (da) 1983-01-09
IL66227A0 (en) 1982-11-30
US4439444A (en) 1984-03-27
AU547405B2 (en) 1985-10-17
PT75209A (fr) 1982-08-01
DE3262870D1 (en) 1985-05-09
FI822408A0 (fi) 1982-07-07
NZ201197A (en) 1985-01-31
NO822122L (no) 1983-01-10
PT75209B (fr) 1984-06-27
AU8513482A (en) 1983-01-13
DD202433A5 (de) 1983-09-14
FI822408L (fi) 1983-01-09
ES513792A0 (es) 1983-08-16
EP0069664A1 (fr) 1983-01-12
EP0069664B1 (fr) 1985-04-03
GR76007B (es) 1984-08-03
HU189599B (en) 1986-07-28
IL66227A (en) 1985-07-31
YU149482A (en) 1984-12-31
AR231288A1 (es) 1984-10-31
FI822408A7 (fi) 1983-01-09

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