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ES8306473A1 - Procedimiento para la obtencion de derivados del 3-amino-1 2-propandiol - Google Patents

Procedimiento para la obtencion de derivados del 3-amino-1 2-propandiol

Info

Publication number
ES8306473A1
ES8306473A1 ES514370A ES514370A ES8306473A1 ES 8306473 A1 ES8306473 A1 ES 8306473A1 ES 514370 A ES514370 A ES 514370A ES 514370 A ES514370 A ES 514370A ES 8306473 A1 ES8306473 A1 ES 8306473A1
Authority
ES
Spain
Prior art keywords
lower alkyl
amino
derivatives
compounds
propane diol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES514370A
Other languages
English (en)
Other versions
ES514370A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES514370A0 publication Critical patent/ES514370A0/es
Publication of ES8306473A1 publication Critical patent/ES8306473A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/12—Preparation of carboxylic acid amides by reactions not involving the formation of carboxamide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
    • C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
    • C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D265/20—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in position 4
    • C07D265/22—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18—Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/22—Radicals substituted by singly bound oxygen or sulfur atoms etherified

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 3-AMINO-1,2-PROPANDIOL. PARA OBTENER COMPUESTOS DE FORMULA (I), DONDE R REPRESENTA UN GRUPO ALQUILO INFERIOR-SULFONILAMINO Y ALK REPRESENTA LOS RADICALES DE FORMULAS (II) O (III), EN UN COMPUESTO DE FORMULA (IV), DONDE R REPRESENTA HIDROGENO O ALQUILO INFERIOR, SE INTRODUCE EL GRUPO ALQUILO INFERIOR-SULFONILO, MEDIANTE REACCION CON UN ACIDO ALCANO INFERIOR-SULFONICO CORRESPONDIENTE, OPCIONALMENTE EN PRESENCIA DE UN AGENTE DE CONDENSACION. ESTOS COMPUESTOS SE EMPLEAN COMO BLOQUEADORES DE LOS ~J-RECEPTORES, PARCIALMENTE DE EFICACIA CARDIOSELECTIVA, POR EJEMPLO PARA EL TRATAMIENTO DE IRREGULARIDADES EN EL RITMO CARDIACO, ANGINA PECTORIS E HIPERTONIA.
ES514370A 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1 2-propandiol Expired ES8306473A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH611880 1980-08-13

Publications (2)

Publication Number Publication Date
ES514370A0 ES514370A0 (es) 1983-06-01
ES8306473A1 true ES8306473A1 (es) 1983-06-01

Family

ID=4304561

Family Applications (8)

Application Number Title Priority Date Filing Date
ES504682A Granted ES504682A0 (es) 1980-08-13 1981-08-11 Procedimiento para la obtencion de derivados del 3-amino-1,2propandiol
ES514371A Granted ES514371A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, s-propandiol
ES514367A Expired ES8305691A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol
ES514366A Granted ES514366A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1,2-propandiol.
ES514365A Expired ES8305689A1 (es) 1980-08-13 1982-07-26 Procedimiento para obtencion de derivados del 3-amino-1,2- propandiol.
ES514369A Expired ES8305693A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol
ES514368A Granted ES514368A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol
ES514370A Expired ES8306473A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1 2-propandiol

Family Applications Before (7)

Application Number Title Priority Date Filing Date
ES504682A Granted ES504682A0 (es) 1980-08-13 1981-08-11 Procedimiento para la obtencion de derivados del 3-amino-1,2propandiol
ES514371A Granted ES514371A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, s-propandiol
ES514367A Expired ES8305691A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol
ES514366A Granted ES514366A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1,2-propandiol.
ES514365A Expired ES8305689A1 (es) 1980-08-13 1982-07-26 Procedimiento para obtencion de derivados del 3-amino-1,2- propandiol.
ES514369A Expired ES8305693A1 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol
ES514368A Granted ES514368A0 (es) 1980-08-13 1982-07-26 Procedimiento para la obtencion de derivados del 3-amino-1, 2-propandiol

Country Status (17)

Country Link
EP (1) EP0045964A1 (es)
JP (1) JPS5759842A (es)
KR (1) KR840002266B1 (es)
AR (6) AR231273A1 (es)
AU (1) AU543647B2 (es)
CA (1) CA1192221A (es)
DD (3) DD202691A5 (es)
DK (1) DK358381A (es)
ES (8) ES504682A0 (es)
FI (1) FI812465L (es)
GR (1) GR74992B (es)
HU (1) HU186342B (es)
IL (1) IL63539A (es)
NO (1) NO812736L (es)
NZ (1) NZ198020A (es)
PT (1) PT73511B (es)
ZA (1) ZA815554B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE58417B1 (en) * 1984-04-27 1993-09-22 Ici Plc Chemical derivatives
GB201101959D0 (en) * 2011-02-04 2011-03-23 Univ Nottingham Novel ether linked compoundsand improved treatments for cardiac and cardiovascular disease

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1398738A (en) * 1972-12-05 1975-06-25 Pfizer Ltd Propanolamine derivatives
FI791727A7 (fi) * 1978-06-05 1981-01-01 Ciba Geigy Ag Menetelmä N-alkyloitujen aminoalkoholien valmistamiseksi.
DD150456A5 (de) * 1979-03-01 1981-09-02 Ciba Geigy Ag Verfahren zur herstellung von derivaten des 3-amino-1,2-propandiols

Also Published As

Publication number Publication date
IL63539A (en) 1984-11-30
ZA815554B (en) 1982-08-25
AU543647B2 (en) 1985-04-26
ES514365A0 (es) 1983-04-16
AR231275A1 (es) 1984-10-31
ES8305694A1 (es) 1983-05-01
ES8301462A1 (es) 1982-12-01
IL63539A0 (en) 1981-11-30
PT73511B (en) 1983-07-06
ES8305690A1 (es) 1983-05-01
ES514371A0 (es) 1983-05-01
NO812736L (no) 1982-02-15
ES504682A0 (es) 1982-12-01
NZ198020A (en) 1985-04-30
AR231273A1 (es) 1984-10-31
AR231274A1 (es) 1984-10-31
ES514367A0 (es) 1983-04-16
AR229188A1 (es) 1983-06-30
AR231631A1 (es) 1985-01-31
DK358381A (da) 1982-02-14
ES8305691A1 (es) 1983-04-16
ES8305689A1 (es) 1983-04-16
GR74992B (es) 1984-07-12
ES8305692A1 (es) 1983-05-01
FI812465A7 (fi) 1982-02-14
ES514369A0 (es) 1983-05-01
KR830006173A (ko) 1983-09-17
ES514366A0 (es) 1983-05-01
AR231278A1 (es) 1984-10-31
DD202691A5 (de) 1983-09-28
HU186342B (en) 1985-07-29
DD202286A5 (de) 1983-09-07
KR840002266B1 (ko) 1984-12-14
ES514370A0 (es) 1983-06-01
AU7402081A (en) 1982-02-18
JPS5759842A (en) 1982-04-10
PT73511A (en) 1981-09-01
DD202532A5 (de) 1983-09-21
FI812465L (fi) 1982-02-14
ES8305693A1 (es) 1983-05-01
ES514368A0 (es) 1983-05-01
EP0045964A1 (de) 1982-02-17
CA1192221A (en) 1985-08-20

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