ES8202822A1 - Procedure for obtaining a benzotiazine derivative (Machine-translation by Google Translate, not legally binding) - Google Patents
Procedure for obtaining a benzotiazine derivative (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES8202822A1 ES8202822A1 ES496877A ES496877A ES8202822A1 ES 8202822 A1 ES8202822 A1 ES 8202822A1 ES 496877 A ES496877 A ES 496877A ES 496877 A ES496877 A ES 496877A ES 8202822 A1 ES8202822 A1 ES 8202822A1
- Authority
- ES
- Spain
- Prior art keywords
- benzotiazine
- translation
- procedure
- obtaining
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- ICSNLGPSRYBMBD-UHFFFAOYSA-N 2-aminopyridine Chemical compound NC1=CC=CC=N1 ICSNLGPSRYBMBD-UHFFFAOYSA-N 0.000 abstract 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 abstract 2
- WYURNTSHIVDZCO-UHFFFAOYSA-N Tetrahydrofuran Chemical compound C1CCOC1 WYURNTSHIVDZCO-UHFFFAOYSA-N 0.000 abstract 2
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 abstract 1
- 230000001476 alcoholic effect Effects 0.000 abstract 1
- 150000008064 anhydrides Chemical class 0.000 abstract 1
- 230000003110 anti-inflammatory effect Effects 0.000 abstract 1
- 238000006243 chemical reaction Methods 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- RIFGWPKJUGCATF-UHFFFAOYSA-N ethyl chloroformate Chemical compound CCOC(Cl)=O RIFGWPKJUGCATF-UHFFFAOYSA-N 0.000 abstract 1
- 238000005755 formation reaction Methods 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 238000007069 methylation reaction Methods 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 229910052708 sodium Inorganic materials 0.000 abstract 1
- 239000011734 sodium Substances 0.000 abstract 1
- YLQBMQCUIZJEEH-UHFFFAOYSA-N tetrahydrofuran Natural products C=1C=COC=1 YLQBMQCUIZJEEH-UHFFFAOYSA-N 0.000 abstract 1
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for obtaining a benzotiazine cderivate. Consists of the formation reaction of the mixed anhydride of 2-carboximetilsacarina with ethyl chlorocarbonate in tetrahydrofuran and in the presence of triethylline, at temperature between 0c and 10c, followed by the reaction with 2-aminopyridine to obtain 2- (N-2- piridilcarbamoil) metilsacarin, which is subjected to an expansion of heterocicle in dimethyl sulfoxide and in presence of sodium alcoxide, followed by an N-methylation with methyl yodide in alcoholic medium and in the presence of an alkaline base. These compounds have pharmacological applications for their analyzes anti-inflammatory activity. (Machine-translation by Google Translate, not legally binding)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES496877A ES496877A0 (en) | 1980-11-14 | 1980-11-14 | PROCEDURE FOR OBTAINING A BENZOTIAZINE DERIVATIVE |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES496877A ES496877A0 (en) | 1980-11-14 | 1980-11-14 | PROCEDURE FOR OBTAINING A BENZOTIAZINE DERIVATIVE |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES8202822A1 true ES8202822A1 (en) | 1982-02-16 |
| ES496877A0 ES496877A0 (en) | 1982-02-16 |
Family
ID=8481394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES496877A Granted ES496877A0 (en) | 1980-11-14 | 1980-11-14 | PROCEDURE FOR OBTAINING A BENZOTIAZINE DERIVATIVE |
Country Status (1)
| Country | Link |
|---|---|
| ES (1) | ES496877A0 (en) |
-
1980
- 1980-11-14 ES ES496877A patent/ES496877A0/en active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| ES496877A0 (en) | 1982-02-16 |
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