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ES8101072A1 - Un procedimiento para la preparacion de nuevas benzamidas sustituidas - Google Patents

Un procedimiento para la preparacion de nuevas benzamidas sustituidas

Info

Publication number
ES8101072A1
ES8101072A1 ES487379A ES487379A ES8101072A1 ES 8101072 A1 ES8101072 A1 ES 8101072A1 ES 487379 A ES487379 A ES 487379A ES 487379 A ES487379 A ES 487379A ES 8101072 A1 ES8101072 A1 ES 8101072A1
Authority
ES
Spain
Prior art keywords
group
alkyl
preparation
pharmaceutical compositions
compositions containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES487379A
Other languages
English (en)
Other versions
ES487379A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES8101072A1 publication Critical patent/ES8101072A1/es
Publication of ES487379A0 publication Critical patent/ES487379A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE BENZAMIDAS SUSTITUIDAS. CONSISTE EN HACER REACCIONAR EN ACIDO DE FORMULA GENERAL (I) O UN DERIVADO REACTIVO DEL MISMO CON UN COMPUESTO DE FORMULA (II). SE OBTIENE UN COMPUESTO DE FORMULA GENERAL (III). *FORMULA* REGULADORES DE LA FUNCION GASTROINTESTINAL.
ES487379A 1978-12-30 1979-12-28 Un procedimiento para la preparacion de nuevas benzamidas sustituidas Granted ES487379A0 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB7850380 1978-12-30
GB7909262 1979-03-15
GB7927831 1979-08-09

Publications (2)

Publication Number Publication Date
ES8101072A1 true ES8101072A1 (es) 1980-12-01
ES487379A0 ES487379A0 (es) 1980-12-01

Family

ID=27260652

Family Applications (1)

Application Number Title Priority Date Filing Date
ES487379A Granted ES487379A0 (es) 1978-12-30 1979-12-28 Un procedimiento para la preparacion de nuevas benzamidas sustituidas

Country Status (14)

Country Link
US (5) US4273778A (es)
EP (3) EP0081054B1 (es)
AR (1) AR225301A1 (es)
AT (1) ATE24320T1 (es)
AU (2) AU527837B2 (es)
CA (2) CA1218062A (es)
DE (3) DE2967642D1 (es)
DK (1) DK553979A (es)
ES (1) ES487379A0 (es)
IE (2) IE49736B1 (es)
IL (1) IL59004A0 (es)
MX (1) MX6255E (es)
NZ (1) NZ192476A (es)
ZA (1) ZA797054B (es)

Families Citing this family (99)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59004A0 (en) * 1978-12-30 1980-03-31 Beecham Group Ltd Substituted benzamides their preparation and pharmaceutical compositions containing them
FR2476088A2 (fr) * 1979-01-16 1981-08-21 Delalande Sa Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique
US4424358A (en) 1979-01-16 1984-01-03 Delalande S.A. β-3-Amino nor-tropane compounds
US4350691A (en) * 1979-12-20 1982-09-21 Beecham Group Limited Certain azabicyclocarboxamides and compositions containing same
US4416683A (en) * 1980-09-16 1983-11-22 Eli Lilly And Company Benzamides, compositions and agricultural method
US5086184A (en) * 1980-09-16 1992-02-04 Dowelanco N-heterocyclic benzamides
US4943634A (en) * 1980-09-16 1990-07-24 Eli Lilly And Company N-heterocyclic benzamides
FR2493848B2 (fr) 1980-11-07 1986-05-16 Delalande Sa Nouveaux derives des nor-tropane et granatane, leur procede de preparation et leur application en therapeutique
ZA818221B (en) * 1980-12-12 1982-10-27 Beecham Group Plc Pharmaceutical compounds
US4430435A (en) 1980-12-24 1984-02-07 Burroughs Wellcome Co. Assay system
EP0057536A1 (en) * 1981-01-26 1982-08-11 Beecham Group Plc Pharmaceutically active compounds
US4353922A (en) * 1981-03-13 1982-10-12 Syntex (U.S.A.) Inc. Anticholinergic bronchodilators
EP0067565A1 (en) * 1981-06-16 1982-12-22 Beecham Group Plc Pharmaceutically active compounds
EP0067615B1 (en) * 1981-06-17 1986-01-08 Beecham Group Plc Alkylthio derivatives of azabicyclobenzamides, their preparation and pharmaceutical compositions
EP0069481A1 (en) * 1981-06-17 1983-01-12 Beecham Group Plc Azabicycloalkyl benzamides, process for their preparation and pharmaceutical compositions containing them
EP0068699A1 (en) * 1981-06-22 1983-01-05 Beecham Group Plc Decahydroquinolyl benzamides, process for their preparation and pharmaceutical compositions containing them
EP0068700A1 (en) * 1981-06-29 1983-01-05 Beecham Group Plc Azobicycloalkylbenzamides, process for their preparation and pharmaceutical compositions containing them
EP0069482A1 (en) * 1981-06-29 1983-01-12 Beecham Group Plc Azabicycloalkyl benzamides, process for their preparation and pharmaceutical compositions containing them
GB2111479A (en) * 1981-10-01 1983-07-06 Beecham Group Plc Benzamides
EP0083737A1 (en) * 1981-12-15 1983-07-20 Beecham Group Plc N-azabicycloalkane benzamides, process for their preparation and pharmaceutical compositions containing them
EP0093488A3 (en) * 1982-03-18 1984-05-23 Beecham Group Plc Nortropyl benzopyrrolinone compounds, process for their preparation and pharmaceutical compositions containing them
ZA832549B (en) * 1982-04-14 1988-09-28 Beecham Group Plc Pharmaceutically active compounds
CA1223873A (en) * 1982-04-14 1987-07-07 Francis D. King Pharmaceutically active compounds
DE3368061D1 (en) * 1982-05-11 1987-01-15 Beecham Group Plc Azabicycloalkane derivatives, their preparation and medicaments containing them
AU1508183A (en) * 1982-06-04 1983-12-08 Beecham Group Plc Benzamide and anilide derivatives of 8-azabicyclo-(3.2.1)- -octane
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
EP0099194A3 (en) * 1982-07-03 1984-04-11 Beecham Group Plc Novel benzamides
JPS5936675A (ja) * 1982-07-13 1984-02-28 サンド・アクチエンゲゼルシヤフト 二環性複素環式カルボン酸アザビシクロアルキルエステルまたはアミド
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EP0102195A3 (en) * 1982-08-03 1984-04-11 Beecham Group Plc Substituted aza bicycloalkyl derivatives with dopamine antagonist activity
EP0126087A1 (en) * 1982-09-24 1984-11-28 Beecham Group Plc Amino-azabicycloalkyl derivatives as dopamine antagonists
GB8302483D0 (en) * 1983-01-29 1983-03-02 Beecham Group Plc Compounds
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GB8317597D0 (en) * 1983-06-29 1983-08-03 Beecham Group Plc Pharmaceutical compounds
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CH664567A5 (de) * 1983-08-26 1988-03-15 Sandoz Ag Aromatische carbonsaeure- und sulfonsaeureester oder -amide.
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FR2446823A1 (fr) * 1979-01-16 1980-08-14 Delalande Sa Nouveaux derives du nor-tropane, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
CA1218062A (en) 1987-02-17
IE49737B1 (en) 1985-12-11
US4273778A (en) 1981-06-16
DE2967692D1 (de) 1989-12-14
DK553979A (da) 1980-08-15
DE2966476D1 (en) 1984-01-12
EP0081054A3 (en) 1983-08-24
EP0081054A2 (en) 1983-06-15
EP0081054B1 (en) 1986-12-17
EP0013138B1 (en) 1983-12-07
US4336259A (en) 1982-06-22
US4705858A (en) 1987-11-10
AU543825B2 (en) 1985-05-02
EP0220339A1 (en) 1987-05-06
NZ192476A (en) 1982-09-14
CA1220473A (en) 1987-04-14
IE49736B1 (en) 1985-12-11
US4544660A (en) 1985-10-01
AU527837B2 (en) 1983-03-24
ZA797054B (en) 1980-12-31
MX6255E (es) 1985-02-15
EP0220339B1 (en) 1989-11-08
IL59004A0 (en) 1980-03-31
ATE24320T1 (de) 1987-01-15
DE2967642D1 (de) 1987-01-29
AU9135182A (en) 1983-03-10
ES487379A0 (es) 1980-12-01
EP0013138A1 (en) 1980-07-09
US4599420A (en) 1986-07-08
AU5425579A (en) 1980-07-03
IE792524L (en) 1980-06-30
AR225301A1 (es) 1982-03-15

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