ES546285A0 - Un metodo para preparar 6-cloro-n-metil-2,3,4,5-tetrahidro- 1h-3-benzazepina - Google Patents

Un metodo para preparar 6-cloro-n-metil-2,3,4,5-tetrahidro- 1h-3-benzazepina

Info

Publication number: ES546285A0
Authority: ES; Spain
Prior art keywords: benzazepine; tetrahydro; chlorine; methyl; preparing
Prior art date: 1984-09-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

ES546285A

Other languages

English (en)

Other versions

ES8609266A1 (es

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

SmithKline Beecham Corp

Original Assignee

SmithKline Beecham Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-09-05

Filing date

1985-08-20

Publication date

1986-09-01

1985-08-20 Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp

1986-09-01 Publication of ES8609266A1 publication Critical patent/ES8609266A1/es

1986-09-01 Publication of ES546285A0 publication Critical patent/ES546285A0/es

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other In-Based Heterocyclic Compounds (AREA)

ES546285A 1984-09-05 1985-08-20 Un metodo para preparar 6-cloro-n-metil-2,3,4,5-tetrahidro- 1h-3-benzazepina Expired ES8609266A1 (es)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US06/647,552 US4541954A (en)	1984-09-05	1984-09-05	Method for preparing 6-chloro-N-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine

Publications (2)

Publication Number	Publication Date
ES8609266A1 ES8609266A1 (es)	1986-09-01
ES546285A0 true ES546285A0 (es)	1986-09-01

Family

ID=24597406

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ES546285A Expired ES8609266A1 (es)	1984-09-05	1985-08-20	Un metodo para preparar 6-cloro-n-metil-2,3,4,5-tetrahidro- 1h-3-benzazepina

Country Status (19)

Country	Link
US (1)	US4541954A (es)
EP (1)	EP0174118A3 (es)
JP (1)	JPS6168469A (es)
KR (1)	KR860002470A (es)
AU (1)	AU581918B2 (es)
CA (1)	CA1244017A (es)
DK (1)	DK379985A (es)
EG (1)	EG17149A (es)
ES (1)	ES8609266A1 (es)
FI (1)	FI853255L (es)
GR (1)	GR852041B (es)
HU (1)	HU194181B (es)
IL (1)	IL76100A0 (es)
NO (1)	NO853255L (es)
NZ (1)	NZ213141A (es)
PH (1)	PH20796A (es)
PT (1)	PT81018B (es)
ZA (1)	ZA856268B (es)
ZW (1)	ZW13385A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
WO1993000811A1 (en) *	1991-07-01	1993-01-21	The General Hospital Corporation	Invertebrate phenylethanolamine transporter and the use thereof
DE69218587T2 (de) *	1991-12-06	1997-08-14	Yuasa Battery Co Ltd	Dünne batterie und monolitische dünne batterie
US6953787B2 (en)	2002-04-12	2005-10-11	Arena Pharmaceuticals, Inc.	5HT2C receptor modulators
PL2332921T3 (pl)	2003-06-17	2016-08-31	Arena Pharm Inc	Chlorowodorek 8-chloro-1-metylo-2,3,4,5-tetrahydro-1H-3-benzazepiny
CA2888392A1 (en)	2003-06-17	2005-03-03	Arena Pharmaceuticals, Inc.	Processes for preparing 3-benzazepines
EP2149562A1 (en)	2004-12-21	2010-02-03	Arena Pharmaceuticals, Inc.	method of preparing (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine hydrochloride hemihydrate
SG158168A1 (en)	2004-12-23	2010-01-29	Arena Pharm Inc	5ht2c receptor modulator compositions and methods of use
EP2518053A1 (en) *	2006-04-03	2012-10-31	Arena Pharmaceuticals, Inc.	Process for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
US8299241B2 (en) *	2006-12-05	2012-10-30	Arena Pharmaceuticals, Inc.	Processes for preparing (R)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1H-3-benzazepine and intermediates thereof
EP2288585A1 (en) *	2008-03-04	2011-03-02	Arena Pharmaceuticals, Inc.	Processes for the preparation of intermediates related to the 5-ht2c agonist (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine
EP2443080A2 (en)	2009-06-18	2012-04-25	Arena Pharmaceuticals, Inc.	Process for the preparation of 5-ht2c receptor agonists
WO2011153206A1 (en)	2010-06-02	2011-12-08	Arena Pharmaceuticals, Inc.	Processes for the preparation of 5-ht2c receptor agonists
MX2013002421A (es)	2010-09-01	2013-05-17	Arena Pharm Inc	Sales no hidroscopicas de agonistas de 5-ht2c.
EP2939677A1 (en)	2010-09-01	2015-11-04	Arena Pharmaceuticals, Inc.	Administration of lorcaserin to indviduals with renal impairment
EP3485878A1 (en)	2010-09-01	2019-05-22	Arena Pharmaceuticals, Inc.	Modified-release dosage forms of 5-ht2c agonists useful for weight management
WO2012030938A1 (en)	2010-09-01	2012-03-08	Arena Pharmaceuticals, Inc.	Salts of lorcaserin with optically active acids
WO2014058441A1 (en)	2012-10-09	2014-04-17	Arena Pharmaceuticals, Inc.	Method of weight management

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CH481110A (de) *	1967-02-17	1969-11-15	Geigy Ag J R	Verfahren zur Herstellung von 1,2,4,5-Tetrahydro-3-azepinen
GB1118688A (en) *	1967-02-17	1968-07-03	Scherico Ltd	Novel benzazepines and process for making same
US4251660A (en) *	1978-08-10	1981-02-17	Smithkline Corporation	Method for preparing tetrahydroisoquinolines
US4200754A (en) *	1979-02-02	1980-04-29	Smithkline Corporation	Method for preparing 7,8-dichloro-1,2,3,4-tetrahydroisoquinoline
EP0080779B1 (en) *	1981-11-27	1986-07-16	Smithkline Beckman Corporation	3-benzazepines as alpha-2 antagonists
IE53962B1 (en) *	1981-11-27	1989-04-26	Smithkline Beckman Corp	3-benzazepines as alpha-2 antagonists
ZA827887B (en) *	1981-11-27	1983-11-30	Smithkline Beckman Corp	Pharmaceutical compositions and method of producing alpha2 antagonism

1984
- 1984-09-05 US US06/647,552 patent/US4541954A/en not_active Expired - Fee Related
1985
- 1985-08-14 EP EP85305780A patent/EP0174118A3/en not_active Ceased
- 1985-08-15 IL IL76100A patent/IL76100A0/xx unknown
- 1985-08-19 ZA ZA856268A patent/ZA856268B/xx unknown
- 1985-08-19 NO NO853255A patent/NO853255L/no unknown
- 1985-08-19 NZ NZ213141A patent/NZ213141A/xx unknown
- 1985-08-19 PH PH32660A patent/PH20796A/en unknown
- 1985-08-19 CA CA000488976A patent/CA1244017A/en not_active Expired
- 1985-08-20 ZW ZW133/85A patent/ZW13385A1/xx unknown
- 1985-08-20 JP JP60183788A patent/JPS6168469A/ja active Pending
- 1985-08-20 ES ES546285A patent/ES8609266A1/es not_active Expired
- 1985-08-21 AU AU46481/85A patent/AU581918B2/en not_active Ceased
- 1985-08-21 DK DK379985A patent/DK379985A/da not_active Application Discontinuation
- 1985-08-21 HU HU853190A patent/HU194181B/hu unknown
- 1985-08-22 GR GR852041A patent/GR852041B/el unknown
- 1985-08-22 KR KR1019850006061A patent/KR860002470A/ko not_active Withdrawn
- 1985-08-23 FI FI853255A patent/FI853255L/fi not_active Application Discontinuation
- 1985-08-23 PT PT81018A patent/PT81018B/pt unknown
- 1985-09-04 EG EG545/85A patent/EG17149A/xx active

Also Published As

Publication number	Publication date
PT81018A (en)	1985-09-01
IL76100A0 (en)	1985-12-31
PT81018B (en)	1987-06-24
FI853255A7 (fi)	1986-03-06
PH20796A (en)	1987-04-14
DK379985D0 (da)	1985-08-21
AU4648185A (en)	1986-03-13
US4541954A (en)	1985-09-17
ZW13385A1 (en)	1985-11-20
FI853255L (fi)	1986-03-06
AU581918B2 (en)	1989-03-09
JPS6168469A (ja)	1986-04-08
EG17149A (en)	1989-06-30
KR860002470A (ko)	1986-04-26
GR852041B (es)	1985-12-19
HU194181B (en)	1988-01-28
ES8609266A1 (es)	1986-09-01
FI853255A0 (fi)	1985-08-23
CA1244017A (en)	1988-11-01
NZ213141A (en)	1988-07-28
HUT38617A (en)	1986-06-30
EP0174118A2 (en)	1986-03-12
NO853255L (no)	1986-03-06
ZA856268B (en)	1986-07-30
DK379985A (da)	1986-03-06
EP0174118A3 (en)	1986-12-30

Publication	Publication Date	Title
ES548135A0 (es)	1986-11-16	Un procedimiento para preparar dioxafosforinanos
ES551518A0 (es)	1987-07-01	Un procedimiento para preparar aril-hidroxamatos
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ES549713A0 (es)	1987-06-16	Un procedimiento para preparar 1,4-dihidropiridinas
ES546285A0 (es)	1986-09-01	Un metodo para preparar 6-cloro-n-metil-2,3,4,5-tetrahidro- 1h-3-benzazepina
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ES549095A0 (es)	1987-01-16	Un metodo para producir derivados de bromodicloroimidazol.
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